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BIMEDA OFFERS AN EFFECTIVE, ECONOMICAL BOVINE RESPIRATORY DISEASE TREATMENT ALTERNATIVE In these days of uncertain profit margins in the cattle business, it is refreshing to know that cattle with bovine respiratory disease (BRD) and other ailments can be treated with a time-proven, yet less expensive alternative to the newer, very expensive drugs now available. This treatment is Bimeda’s Sustain III®. Sustain III® is a sustained-release oral bolus containing 32.1 grams of sulfamethazine. 1 bolus provides adequate sulfamethazine to treat 200 lbs. of body weight. Boluses are scored to allow dosing at 100 lb. increments. Therapeutic blood levels are reached within 6 hours of administration and persist for 72 hours, so one treatment lasts 3 days! Sustain III® is labeled for treatment of Bacterial Pneumonia and BRD caused by bacteria (Pasteurella spp.), Colibacillosis (E. coli), Necrotic pododermatitis (Foot Rot), Calf Diphtheria Fusobacterium necrophorum, and Acute Metritis caused by Streptococcus spp. SEE THE CHART ON THE FOLLOWING PAGE COMPARING THE COST OF TREATMENT OF COMMONLY AVAILABLE ANTIBIOTICS.

Page 1 of 2 Sustain III is a registered trademark of Bimeda, Inc.


Comparison of Leading Antibiotic Treatments Cost to Treat a 600 lb Calf for Respiratory Disease Product

Antibiotic

Manufacturer

Dosage Form

Dosage Route

Drug Concentration

Unit Size

Unit Price*

Dosage/Treatment Schedule

Total Dosage to Treat 600 lb

Cost to Treat 600 lb

Withdrawal Time

A180®

danofloxacin mesylate

Pfizer Animal Health

Injectable

SC

180 mg/mL

250 mL

$289.95

1.5 mL/100 lb once, 2nd dose 48 hours later

9.0 mL x 2

$20.88

4 days

Baytril® 100

enrofloxacin

Bayer Animal Health

Injectable

SC

100 mg/mL

250 mL

$189.95

3.4 mL - 5.7 mL/100 lb

20.4 mL - 34.2 mL

$15.50 - $25.99

28 days

Draxxin®

tulathromycin

Pfizer Animal Health

Injectable

SC

100 mg/mL

100 mL

$399.95

1.1 mL/100 lb

6.6 mL

$26.40

18 days

Excede®

ceftiofur crystalline free acid

Pfizer Animal Health

Injectable

SC

200 mg/mL

100 mL

$186.95

1.5 mL/100 lb

9.0 mL

$16.83

13 days

Excenel® RTU

ceftiofur hydrochloride

Pfizer Animal Health

Injectable

IM,SC

50 mg/mL

100 mL

$72.95

1.0 mL – 2.0 mL/100 lb daily for three days

18.0 mL – 36.0 mL

$13.13 - $26.26

3 days

Micotil® 300

tilmicosin

Elanco Animal Health

Injectable

SC

300 mg/mL

250 mL

$349.95

1.5 mL/100 lb

9.0 mL

$12.60

28 days

Naxcel®

ceftiofur sodium

Pfizer Animal Health

Injectable

IM,SC

50 mg/mL

4 g - 80 mL

$69.95

1.0 mL - 2.0 mL/100 lb daily for three days

18.0 mL - 36.0 mL

$15.74 - $31.48

4 days

Nuflor®

florfenicol

Intervet Schering-Plough

Injectable

IM,SC

300 mg/mL

500 mL

$238.00

IM - 3 mL/100 lb, 2nd dose 48 hours later SC - 6 mL/100 lb

18.0 mL x 2 36.0 mL

$17.14 $17.14

28 days - IM 38 days - SC

Nuflor Gold®

florfenicol

Intervet Schering-Plough

Injectable

SC

300 mg/mL

500 mL

$249.00

SC - 6 mL/100 lb

36.0 mL

$17.93

44 days

Resflor Gold®

florfenicol

Intervet Schering-Plough

Injectable

SC

300 mg/mL

500 mL

$266.00

SC - 6 mL/100 lb

36.0 mL

$19.15

38 days

Polyflex®

ampicillin

Ft. Dodge Animal Health

Injectable

IM

25 g

25 g

$45.49

2.0 mg - 5.0 mg/lb daily for three days

3.6 g - 9.0 g

$6.55 - $16.38

6 days

Sustain III® Cattle Bolus

sulfamethazine

Bimeda, Inc.

Bolus

Oral

32.1 g

50 Count

$63.95

1 bolus/200 lb

3 boluses

$3.84

12 days

* Retail prices obtained from internet sites on March 23, 2010. A180, Draxxin, Excede, Excenel RTU and Naxcel are registered trademarks of Pfizer Inc. Baytril 100 is a registered trademark of Bayer Animal Health. Micotil is a registered trademark of Elanco Animal Health. Nuflor, Nuflor Gold and Resflor Gold are registered trademarks of Intervet International B.V. or affiliated companies or licensors. Polyflex is a registered trademark of Ft. Dodge Animal Health Sustain III is a registered trademark of Bimeda, Inc.

Bimeda, Inc. • One Tower Lane, Suite 2250, Oakbrook Terrace, IL 60181 USA Toll Free Tel.: (888) 524-6332 / Toll Free Fax.: (877) 888-7035 sales@bimedaus.com / www.bimeda.com

The information contained in this chart is for general information purposes only. The information is provided by Bimeda, Inc., and while we endeavour to keep the information current, up to date and correct, we make no representations or warranties of any kind, express or implied, about the completeness, accuracy, reliability, suitability, or availability with respect to the information, products, or graphics. Any reliance you place on such information is therefore strictly at your own risk. In no event shall we be liable for any loss or damage including without limitation, indirect or consequential loss or damage, or loss or damage whatsoever arising from loss of profits arising out of, or in connection with the information.

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