OriginAI HCLS - Solution Brief

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OriginAI® Infrastructure Solutions for Healthcare and Life Sciences

Pre-validated, high-performance solutions to accelerate discovery, care, and operations

Overview

By 2030, artificial intelligence (AI) could unlock a US$868 billion opportunity¹ for healthcare and life science (HCLS) organizations, driving innovations ranging from AI-powered trial management and precision medicine to next-generation patient care. Complex regulations, fragmented data, and security pose the biggest challenges to AI adoption, leading many organizations to acquire their own AI infrastructure.

To turn AI potential into meaningful outcomes, HCLS organizations need trusted partners that can deliver compliant, high-performance infrastructure and simplify AI operations. Penguin Solutions has a proven track record in regulated industries, providing the reliability, performance, and flexibility needed to operationalize AI at scale. OriginAI by Penguin Solutions builds on this expertise, offering a complete AI infrastructure solution that accelerates time-to-insight while ensuring compliance and operational excellence.

Key Features

Pre-validated AI infrastructure architectures: Tailored to regulated HCLS workloads to speed deployment and reduce risk

Modular framework: Designed to scale compute, storage, and fabric as data and use cases grow

Intelligent software and services: Maintain and optimize peak training and inference infrastructure performance

End-to-end lifecycle management: Accelerate time-to-value and ensure operational efficiency from deployment to ongoing support

AI in HCLS: Opportunities, realities,

and roadblocks

Improving patient care and business operations requires converting data into actionable decisions, which is made possible with the right AI infrastructure foundation. The healthcare industry generates approximately 30% of the world’s total data volume2, yet many organizations struggle to make data usable across clinical, research, and operational workflows. Those investing in modern high-performance computing (HPC) infrastructure are best positioned to operationalize AI, scale safely, and realize value.

Generative AI investments are set to triple by 2026 and could unlock up to $382B in potential savings by 2027 through intelligent automation3—provided companies build the infrastructure needed to support regulated, performance-intensive workloads.

Even with this momentum, life sciences research, healthcare delivery, and clinical operations organizations face four persistent barriers:

Data fragmentation and interoperability gaps that slow insight generation.

Security, privacy, and compliance pressures tied to sensitive or regulated data.

Workflow and integration challenges that delay clinical or research adoption.

How OriginAI solves HCLS challenges

Limited in-house expertise to deploy and manage large-scale AI or HPC environments.

OriginAI is an AI factory infrastructure solution built upon proven, pre-defined AI infrastructure architectures backed by Penguin Solutions ICE ClusterWare™ intelligent management software and expert services. Together, this solution helps HCLS organizations design, build, deploy, and manage AI infrastructure.

Pre-validated, scalable reference architectures integrate compute, storage, and networking to overcome fragmented or siloed data. These proven architectures reduce deployment risks, leading to faster time-to-insight and better data utilization for our customers.

Secure, on-premises configurations are designed for regulated workloads with documented deployment patterns, directly addressing privacy and compliance complexity. Customers can maintain data governance and sovereignty while meeting stringent compliance standards.

Intelligent infrastructure management via our ICE ClusterWare software platform provides cluster health and performance monitoring and tuning that tackle potential degradations head-on. As a result, your IT team can spend less time managing infrastructure and more time on higher value work such as optimizing service delivery for healthcare providers, driving projects that improve clinical and administrative workflows, and supporting initiatives that measurably impact patient outcomes.

Expert lifecycle services spanning the design, build, deploy, and manage phases bridge skills and resource gaps within your organization while delivering simplified operations and peace of mind. The result: Optimized performance that increases your ROI.

Real-world impact

A recent survey of more than 600 HCLS professionals found that over 80% believe AI will revolutionize the field in the next three to five years.4 Meanwhile, leading organizations are already achieving measurable results. OriginAI empowers companies to realize these benefits, enabling high-impact workloads that accelerate insight and improve outcomes across research, clinical, and operational domains.

Life sciences

Drug discovery, genomics, and multiomics research move faster, shortening time-to-market for new therapies.

Tangible results include:

Healthcare delivery

More efficient scheduling and patient care, medical imaging analysis, patient risk stratification, and predictive care models means more personalized treatment.

Operational and workflow efficiency

Automation and decision support streamline clinical and research processes, reduce manual effort, and allow teams to focus on high-value work.

Significantly accelerated discovery and diagnostic workflows, helping teams reach insights sooner.

Substantially improved accuracy across clinical and research outcomes, fostering more reliable data, more precise insights, and ultimately, better patient care.

Drastically reduced operational complexity and optimized cost efficiencies through streamlined processes and intelligent resource allocation.

Future-ready scalability that adapts seamlessly to rapidly evolving AI and HPC workloads, ensuring sustained innovation and competitive advantage.

OriginAI features for HCLS organizations

OriginAI combines powerful infrastructure, intelligent management, and expert services to accelerate AI-driven discovery and clinical innovation in healthcare and life sciences.

Flexible, high-performance infrastructure

OriginAI delivers AI infrastructure designed to power innovative HCLS research and clinical workflows. With multiple compute options—including Penguin Solutions, NVIDIA Platform, and Dell Technologies servers—organizations can choose the platforms that best fit their needs. Pre-validated network and storage designs also provide reliable, scalable performance, helping teams train models faster, run advanced inference, and turn data into actionable insights.

ICE ClusterWare intelligent cluster management software

ICE ClusterWare rapidly transforms raw infrastructure into high-performing AI clusters, providing continuous, proactive performance management for maximum efficiency and reliability in HCLS workflows, such as gene analysis, trend mapping, and image classification. Its intelligent automation simplifies the administration of clusters while enabling seamless scaling of nodes as your AI initiatives grow, all while ensuring consistent performance for critical research and clinical applications.

End-to-end cluster management and optimization services

At the core of OriginAI is the complete Penguin Solutions cluster lifecycle services model—design, build, deploy, and manage—that augments your team’s capabilities with proven expertise in increasing infrastructure ROI and AI effectiveness. With field-tested experience and specialized technology, Penguin Solutions services accelerate time-to-value, ensure peak performance, and enable AI initiatives to grow and evolve.

For HCLS this means faster research insights, more efficient clinical workflows, and the confidence that critical data and systems remain secure and compliant.

Why Penguin Solutions?

HCLS executives face mounting pressure to accelerate innovation by speeding up the pace of discovery improving patient outcomes, and operating more efficiently—all while managing costs and ensuring compliance. Success requires more than solid data and advanced algorithms; it also demands purpose-built AI infrastructure designed for the unique challenges and complexity of HCLS.

Penguin Solutions brings unparalleled AI infrastructure experience with more than 3.3 billion hours of GPU runtime management, over 89,000 GPUs deployed, and strategic partnerships with industry leaders such as NVIDIA and Dell. This expertise translates into faster deployments, higher reliability, and peak performance for HCLS AI workloads. With Penguin Solutions OriginAI, HCLS organizations are better equipped to turn the potential of AI into practical, productive, and profitable outcomes.

Ready to transform AI potential into measurable outcomes? Schedule a session with our infrastructure experts to scope your requirements, develop your implementation roadmap, and accelerate your results.

Resources

1.https://www.strategyand.pwc.com/de/en/industries/pharma-life-sciences/ai-healthcare-revolution.html

2. https://www.sciencedirect.com/science/article/pii/S2414644724000034#bib0001

3. https://my.idc.com/research/viewtoc.jsp?containerId=US52217524

4.https://blogs.nvidia.com/blog/ai-healthcare-life-sciences-survey-2025/

Contact Us

For sales queries, pl ease contact sales@penguinsolutions.com

To learn more about OriginAI and other Pen guin So lution s products, please visit: ww w.penguinsolution s.com

© 2025 Penguin Solutions, Inc. All rights reserved. Penguin Solutions, Penguin Computing, OriginAI, and ICE ClusterWare are trademarks or registered trademarks of Penguin Solutions. All other product names, trademarks, and registered trademarks are the property of their respective owners. All company, product, and service names used in this document are for identification purposes only. Use of these names, tradem arks, and brands does not imply endorsement.

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