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Reactive Distillation Process for Free Radical Halogenation Inventors:

Patent Number: Issue Date:

Barnum, Chris S.; Blaisdell, Charles T. 5,449,801 September 12, 1995

Docket Number: UD00-03

The present invention relates to a process for the selective, high-yield halogenation of particular silyl, phenyl, or carbonyl compounds under reactive distillation conditions which doesn’t require recycling of the starting material. Use of Hydrostatic Pressure to Inhibit and Reverse Protein Aggregation and Facilitate Protein Refolding Inventors:

Serial Number: Filing Date:

Robinson, Anne S.; Robinson, Clifford R.; Foguel, Debora; Silva, Jerson L. 10/673,000 September 26, 2003

Docket Number: UD00-01

A novel approach is described for reversing aggregation and increasing refolding by application of hydrostatic pressure. A protein of interest in an aggregated, or inclusion body, or other non-native or inactive state is subjected to high hydrostatic pressure. This treatment dissociates the aggregated protein to states (or conformations) competent for refolding and results in increased formation of native protein once pressure is released. The technique can facilitate conversion of non-native proteins, including inclusion bodies and aggregates, to native proteins without addition of chaotropic agents, changes in buffer, or large-scale dilution of reagents required for traditional refolding methods.


INVENTIONS - Technologies Available for Licensing

Support Mesoporous Carbon Ultrafiltration Membrane and Process for Making the Same Inventors:

Patent Number: Issue Date:

Strano, Michael; Foley, Henry C.; Agarwal, Hans 6,719,147 April 13, 2004

Docket Number: UD00-04

A novel supported mesoporous carbon ultrafiltration membrane and process for producing the same. The membranes comprise a mesoporous carbon layer that exists both within and external to the porous support. A liquid polymer precursor composition comprising both carbonizing and non-carbonizing templating polymers is deposited on the porous metal support. The coated support is then heated in an inert-gas atmosphere to pyrolyze the polymeric precursor and form a mesoporous carbon layer on and within the support. An Undergraduate Teaching Lab: Transient Heat Conduction Using Thermocouples, Thermochromic Liquid Crystals, and Numerical Simulation Inventors:

Patent Number: Issue Date:

Prasad, Ajay K.; Stahl, Roger 6,783,368 August 31, 2004

Docket Number: UD00-10

This is a novel experiment to demonstrate transient heat conduction for undergraduate students. The experiment provides a visual appreciation of temperature contours, along with quantitative measurements. Students also perform a numerical simulation of the transient conduction problem and compare results with the experiment.

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