PWJ - PAINWeek Journal Vol 9, Q1 | 2021

Page 61

short cuts

Are some flare-ups of

urologic chronic pelvic pain syndrome (ucpps) caused by pollen? Pollen levels were compared in


Frozen shoulder— adhesive capsulitis—

Exercise is often recommended

for patients with low back pain (LBP).

is a common, painful fibroproliferative tissue fibrosis affecting 2.4 out of

In a review of



people per year. from an overall group of

From 65 studies with




34 studies with

in 8 studies, and assessed every 2 weeks for 1 year as part of MAPP: Multidisciplinary Approach to the study of Chronic Pelvic Pain. 1 to 2 days after pollen counts exceeded a threshold, the odds of a symptom flare increased by

22% 33%


did not provide a mechanism of benefit for exercise in people with chronic LBP.

Of the remaining studies, most provided >1 mechanism, from which

30 three


were included in pairwise meta-analyses and 39 studies with

2736 participants

in all patients with UCPPS, and


in network meta-analyses.

Only intra-articular corticosteroid was

associated with statistical and clinical superiority compared with other interventions in the short-term for pain and function.3

unique mechanisms

were identified and grouped into 5 themes: neuromuscular, n=105 (44%); psychosocial, n=8 (36%); neurophysiological, n=22 (9%); cardiometabolic, n=15 (6%); and tissue healing, n=12 (5%).5

in those with allergies.1


commonly co-occur in those with multiple sclerosis (MS).

A review of 8 studies and


Does early improvement in 1 affect the other 2?

patients patients compared opioids given alone, nitrous oxide given alone, and intranasal ketamine given with nitrous oxide to determine analgesic properties of ketamine.

The end result: treatment with IV ketamine in analgesic doses of 0.1 to 0.2 mg/kg was at least as effective as opioids administered alone in pain reduction.2

with fibromyalgia—mean age 52, 94% female—completed 14 days of actigraphy to determine how activity affected their sleep. Average activity intervals (12:00–3:00p, 3:00–6:00p and 6:00–9:00p) were studied.


increased physical activity in the afternoon and early evening caused sleep disturbance, especially in individuals with higher pain levels.4


with MS, 86% women, participated in an 8-week self-management (n = 69) or education (n = 85) intervention via telephone. Early ↓ in depressive symptoms = overall ↓ in pain/fatigue impact (P<.01). Early ↓ in fatigue = overall ↓ in depressive symptom severity (P=.04) but not pain interference. Early ↓ in pain interference did not reduce the other 2 symptoms.6

1.  2.  3.  4.  5.  6.