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==== ==== Have you taken any Antidepressants while pregnant? Is your newborn child suffering from birth defects? Find out how to receive financial compensation by calling 1-888-641-2991 1-888-641-2991 ==== ====

Paxil, a popular antidepressant has been linked to birth defects - specifically heart problems - in children whose mothers took the drug during their first trimester of pregnancy. Because of this known birth defect risk, women and doctors have been warned to avoid Paxil during pregnancy. Paxil - known generically as paroxetine - was brought to market by GlaxoSmithKline in 1992, and by 2006, Paxil was the fifth most-commonly prescribed antidepressant in the US, with more than 19.7 million prescriptions. Paxil is part of a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs). SSRIs affect serotonin levels in the brain, a chemical neurotransmitter. In a healthy person, serotonin is produced in the brain on an ongoing basis and in response to pleasure-giving experiences. In September 2005, the FDA and GlaxoSmithKline alerted doctors about a new study on major birth defects seen in babies born to women who took the antidepressant Paxil during the first trimester of pregnancy. In the study - conducted by the drug maker - of more than 3,500 pregnant women, Paxil was linked to twice as many major birth defects as other antidepressants. Most of the birth defects seen in the study were heart related; the most common heart malformations were ventricular septal defects, which are holes between the heart's two main pumping chambers. The FDA said GlaxoSmithKline would be updating the Paxil label's precautions section to include data from this study. In December 2005, the FDA again announced that it was requiring GlaxoSmithKline to add additional warnings about Paxil birth defects to the drug's prescribing information. At the same time, the FDA said it had also moved Paxil to another pregnancy category. The FDA had previously classified the Paxil birth defect risk as Category C (Risk of Fetal Harm Cannot be Ruled Out). The new Paxil labeling now classified the birth defect risk as Category D (Positive Evidence of Fetal Risk). The FDA took the action because the early results of two more studies showed that women who took Paxil during the first three months of pregnancy were about one and a half to two times as likely to have a baby with a heart defect as women who received other antidepressants or women in the general population. In general, these types of defects ranged in severity from those that were minor and resolved without treatment to those that caused serious symptoms and needed to be repaired surgically. Doctors have been advised to discuss the potential risk of birth defects with patients taking Paxil who plan to become pregnant or are in their first three months of pregnancy. Physicians have also been cautioned to consider discontinuing Paxil (and switching to another antidepressant if indicated) in these patients.


Women need to be aware that Paxil should usually not be taken during pregnancy. Women taking Paxil who are pregnant or plan to become pregnant need to talk to their physicians about the potential risks of taking the drug during pregnancy. However, patients taking Paxil should not stop taking it without speaking with their doctor. If you wish to learn more about Paxil and birth defects, please visit the-feed-store.com to read more articles on this subject.

More more information on Paxil related birth defects you can go to the following websites; The Feed Store [http://www.the-feed-store.com/defectivedrugsrss.asp?feedid=531] or YourLawyer.Com

Article Source: http://EzineArticles.com/?expert=Jeff_Goldstein

==== ==== Have you taken any Antidepressants while pregnant? Is your newborn child suffering from birth defects? Find out how to receive financial compensation by calling 1-888-641-2991 1-888-641-2991 ==== ====

Is your child suffering from birth defects due to taking an anti depressant while pregnant?  

Have you or a loved one taken anti depressants while pregnant and had a child born with birth defects? Call 1-888-641-2991 for financial com...