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N a t u r a l M e d

A p o t h e c a r y ,

I n c .


Te s t o s t e r o n e - C o r t i s o l - E s t r o g e n

Hormonal     chaos?    If  your   around  the  age  of  forty  you  may  think  the  only  hormonal  chaos  going  on  is  happening  to  the   opposite  sex.    A  common   misconcep;on  is   that  females  are  the  only  ones   that  go  through  “the  change”  during   their  40’s   and  50’s.    Studies  show  that  70%  of  the  general  public  believes  that  men  experience  a  mid-­‐life  stage  similar  to  menopause   in  women.     When  these  mid-­‐life  stages   affect   women   they   experience  physical  symptoms   that  are   very  no;ceable  and   last  anywhere  from  months   to  5   years,   where  men   experience   subtle  changes   over  a   longer   period  of   ;me   (anywhere   from  10-­‐15  years).  So  while  the  days  of   high  school   and  puberty  are   long  gone  and  while  you  may   feel  stable  hormonally   there  is  a  good  chance  that  you  are  entering  or  experiencing  andropause.       Andropause   technically   describes   the   progressive   decline   in   androgen   produc;on.     During   andropause   there   are   three   main   changes   that  occur   almost   like   a   chain   reac;on,  there   is   a   drop   in   testosterone   levels,   an   increase  in   Sex   Hormone   Binding   Globulin   (SHBG),   and   an   increase   in   produc;on   of   aromatase.     When   it   comes   to   hormones   one   important   thing   to   understand   is   what’s   available  and   what  isn’t.    More  than  95%  of   hormones   found  in  the   blood   are   bound   to   circula;ng   proteins   and   in   this   bound   state,   they   are  unable  to   fit  into   receptors.     Therefore,   these  hormones   will  not  be  delivered  to  ;ssues  and  are  considered  inac;ve,  or  non-­‐ bioavailable  and  flushed  out  of  the  system.     While  andropause  is   part  of   the  natural  aging  process   the  side   effects   from  hormone  imbalance   may   cause  a  disrup;on   in  living  a   quality  and  fulfilling  daily  life.    Testosterone  replacement  helps,  not   only  with  symptoms,  but  also  decreases  disease  risks   that  are  usually  associated  with  the  aging   process,  such  as,  heart   disease  and   diabetes.       With   this   handout  our   goal  is   to  provide  you   with: • • • •

The roles  of  hormones  in  men. Explain  responsible  testosterone  replacement  and  what  it  will  and  won’t  do  for  you.   Explain  the  difference  between  blood  and  saliva  tes;ng  when  looking  at  hormone  levels. Condi;ons  to  consider  when  beginning  treatment  and  what  to  expect.

We  hope  you  find   this  informa;on  useful  and  understand  that  we  are  here  to  help  you  and  your  physician  achieve  the   best  results.     We  look  forward  to  working  with  you  and  please  do  not  hesitate  to  contact   us  if  you   have  any  ques;ons  or   if   we  can  assist  you  in  any  other  way.


Testosterone  to  men  is   like   estrogen   to  women,  and  it  is   men’s   most  crucial   hormone.    This   hormone  provides   males   with   the   typical  masculine  traits   like   more   body   hair,   and   a   deeper   voice   and   is   very   important   in  the  development   and   maintenance   of  male  reproduc;ve  ;ssues  and  characteris;cs   such   as   sex   drive,  stamina,  and  needed  to  produce  erec;ons.     While  it   does   help  to  bulk  up   and  build   muscle,   testosterone   can   be   a   “fat   buster”   as   it   increases   metabolism   and   helps   with  the  release  of   fat   from   fat   cells   and  prevents   the  body   from  storing   excess  fat.    Also  responsible  for  aiding  in  several   metabolic  func;ons   including   bone  forma;on,   liver  func;on,   prostate  gland   growth  and  produc;on   of   blood  cells   in  bone   marrow.     This   single   hormone   is   extremely   important   for   everyday   func;oning  of  a  male   throughout  his   life.    The  body   naturally   produces   testosterone   through  a   few   steps.   These   steps   involve   several   hormones   being   released   through   different  glands:

   The  hypothalamus  begins  the  process  by  releasing  Gonadotropin-­‐releasing  Hormone  (GnRH)  to  the  pituitary  gland.  The  pituitary  gland  releases  Luteinizing  Hormone  (LH)  and  Follicle  S;mula;ng  Hormone  (FSH)  Together  LH  and  FSH  travel  to  the  testes  LH  binds  to  Leydig  receptors  in  the  testes  and  FSH  binds  to  Follicle  S;mula;ng  Hormone  receptors.  The  body  begins  to  produce  testosterone   This  process  provides  the  body  with  natural  levels  of  testosterone.  The  body  will  also  trigger  signals  to  stop  releasing   testosterone  when  levels  are  normal.  This  allows  for  feedback  loop  to  trigger  the  body  to  produce  or  stop  producing   testosterone.    Testosterone  begins  to  decrease  very  slowly  beginning  around  the  age  of  30,  and  by  the  age  of  50   testosterone  levels  have  usually  dropped  by  about  40%  from  peak  levels  of  younger  years.    

Benefits of testosterone include: • Significant increase  in  libido  (sex  drive  and  sex  desire). • Improvement  in  the  quality  and  frequency  of  erec;ons,  and  strength  of  orgasm. • Increase  in  muscle  mass  and  strength. • Increase  in  bone  density  above  the  fracture  threshold  and  in  the  spine. • Decrease  in  midsec;on  fat. • Improvement  in  mental  func;on  (cri;cal  thinking  and  decision  making),  and  verbal  fluency. • Improved  athle;c  agility  and  performance,  and  restora;on  of  compe;;ve  edge. • Increased  endurance.   • Improvement  in  lipid  profile  (decreased  triglycerides,  increased  HDLs,  lowered  LDLs). • Improvement  in  blood  sugar  control  (testosterone  decreases  insulin  resistance,  which  can  cause  type  2  diabetes). • Improvement  in  an  overall  sense  of  well-­‐being  and  friendliness.   • Decreased  anger,  irritability,  sadness,  ;redness,  and  nervousness.

SYMPTOMS FROM TO MUCH OR TOO LITTLE... Testosterone Deficiency Anemia Bone Loss Decreased  Libido Decreased  Immunity Depression Erec;le  Dysfunc;on Fa;gue

Fuzzy Thinking Hair  Loss Heart  Palpita;on Incon;nence   Lack  Of  Mo;va;on Loss  Of  Muscle  Tone Memory  Problems

Muscle Weakness Osteoporosis Reduced  Orgasm  Intensity Sleep  Disturbances Thinning  Skin

Testosterone Excess Acne Anxiousness Aggressiveness Impulsivity

Increased Libido Mood  Swings Rage Deepening  Of  The  Voice

What can you do now to help with testosterone levels? • Exercise regularly!    Exercise  increases  the  body’s  produc;on  of  testosterone,  decreases  belly  fat  which  reduces   aroma;za;on  (which  is  an  over  conversion  of  estrogen).    Lowers  your  blood  pressure,  improves  circula;on  all  of   which  helps  with  erec;le  dysfunc;on.     • Lose  weight!    Estrogen  loves  fat  cells  and  the  more  fat  you  carry  you  will  likely  have  more  aromatase  that  will  covert   the  testosterone  into  estrogen. • Take  a  well  balanced,  quality  mul;vitamin.    Talk  to  your  prescriber  or  pharmacist  about  whether  supplementa;on   of  saw  palmeco,  or  extra  support  with  zinc,  vitamin  c,  vitamin  e,  and/or  selenium  will  be  beneficial. • Reduce  your  stress  levels.    While  this  may  be  next  to  impossible,  work  on  stress  management.    Stress  will  affect   testosterone  levels  but  it  also  can  exasperate  sexual  dysfunc;on  and  will  wreak  havoc  on  your  adrenals  and   endocrine  system.  

What will testosterone not make you do? Over the   last  few  years,  testosterone  replacement  therapy  has  received  bad  publicity   largely   due  to  concerns   of   abuse  –  especially  among  athletes  and  bodybuilders.    Testosterone  replacement  when  used   responsibly   is  intended  to   produce   and  maintain  the   concentra;ons  of   testosterone,  without  providing   unnecessary   and  poten;ally   dangerous   excess.    Doses   should   be  individually   tailored  to   alleviate   andropausal   symptoms   without   causing  side  effects   or   safety   concerns.  When   using   testosterone  responsibly  it  will  not: • • • •

Help you  bench  press  more  than  your  workout  partner.   Allow  you  to  par;cipate  in  bodybuilding  compe;;ons. Return  your  randiness  to  that  of  an  18  year-­‐old. Allow  you  to  recapture  your  lost  youth.



C o r t i s o l


E s t r o g e n

DHEA The  hormone  DHEA   (Dehydroepiandrosterone)   comes   from   the  adrenal  gland  and  acts   as   the  precursor  to  many  steroid  hormones,   including   cor;sol,  estrogen,  and  testosterone.   The  body  uses  DHEA  to  make  androgens  and  estrogens,  the  male  and  female  sex  hormones.   DHEA  levels  peak   at  about  age   25,  then  go   down   steadily   as   you  get   older.  People  who  are   70,   for  example,  tend  to   have  DHEA   levels   about   80%  lower  than  young  adults.    Lower  than   normal  levels   of  DHEA  have  been  associated  with  osteoporosis,  heart  disease,  memory   loss,   and  breast  cancer.  There  is  no  proof  that  low   levels   of  DHEA  cause  these  condi;ons,  or  that   taking   DHEA   can   help   prevent   them.   When   natural   DHEA   produc;on   declines   supplementa;on   can   improve   erec;le   dysfunc;on   symptoms,   orgasmic   func;on,   sexual   desire,  and  overall   sexual  sa;sfac;on.    Studies   also   show   DHEA   supplementa;on   can  also   show   improvements   in   bone   density   as   well   as   improving   aging   skin;   like   increased   skin   thickness,  improved  skin  hydra;on,  and  decreased  facial  skin  pigmenta;on.

Cortisol   Cor;sol  is   a   steroid   hormone  secreted   by  the  adrenal  cortex,   located  on  top  of   both  kidneys.   Your   pituitary   gland,   located  in  the  brain,  determines  how  much  cor;sol  is  released;  this   can  vary  from  one  person  to  the   next.  The   benefits  of   cor;sol  include  blood  pressure  management,  reduced  inflamma;on,  and  a   stronger  immune  system.  This   stress-­‐figh;ng   hormone   converts   protein   into   fuel   when   you're   under   physical   or   psychological   stress   evoked   by   trauma;c   events.   Once   your   brain   no   longer   perceives   a   situa;on   as   threatening,   your   cor;sol   levels   return   to   normal.     When   the  adrenal   glands   become  fa;gued,   they   may   produce   lower   amounts   of   cor;sol,   resul;ng   in   a   chronic  low   level  of   cor;sol   in   the   blood.   Low   levels   of   cor;sol   can  result  in  chronic   fa;gue  and  can   also   lead  to  a   disease  of  the  endocrine  system  known  as   Addison's   disease.      Low   levels  of  cor;sol  may  also   lead  to  reduced  thyroid   func;on,  mild  depression,  inflamma;on,  and  lowered  immune  func;on.

Estrogen   Men   require   a   small   amount   of   estrogen   for   a   healthy   heart,   brain   func;on,  bones,  and  libido.     Estrogen  and  testosterone  are  held  in   balance,  but   as   testosterone   levels   drop   during   andropause,   estrogen   produc;on   either   increases   or   remains   steady,   causing   an   imbalance  in   hormones.     Increases   in   estrogen  produc;on  may  be  from  aging,  diet  and  weight,  nutri;onal  deficiencies,   and/or   excessive   alcohol   use.     When   hormone   levels   become  imbalanced   and   testosterone  levels  drop  too  low,  estrogen  acaches  to  the  receptor  sites  on   cells   that   are  normally   occupied   by   testosterone.   High   estrogen   levels   in   men   may   eventually   lead  to   diabetes   or   heart   disease,  problems   with   infer;lity,  erec;le   dysfunc;on,  and  other  symptoms  associated  with  low  testosterone.

Have symptoms but unsure what to do next? Talk   to  your  prescriber  about  your  symptoms  and  looking   at   your   testosterone  levels.     Most   physicians   do   a   blood   test   to   measure   hormones   levels   which   is   fine   when   you   are  just  looking  at  testosterone.    We  have  some  prescribers   that  find  it  beneficial  to  do  saliva   testing.    More  than  95%   of   hormones   found  in   the   blood  are  bound   to   circulating   proteins  and  in  this   bound  state,  they  are  unable  to  fit  into   receptors.    Therefore,  these  hormones  will  not  be  delivered   to  tissues   and  are  considered  inactive,  or  non-­‐bioavailable.     The   bound   hormones   that   are  measured   in  blood   testing   are   too   large  to   pass   through   the   cell   membranes   of   the   salivary   glands.     Only   the   unbound   hormones   may   pass  

through into  the  saliva.      These  hormones  are  going  to   be,   the   “free”   or   bioavailable   hormones   that   are   going  to  be  delivered  to  the  receptors  in   the  tissue  of   the   body.     This   concentration   of   free   hormones   is   going   to   show   a   more   clinically   significant   result   of   hormones   levels,  thus  making  saliva   testing  far  more   superior.     Saliva   tests   are   very   stable   and   can   be   collected  in  the  privacy  of   your  own  home,  stored   at   room   temperature,   and   are   stable   for   an   extended   period   of  time.    For  information  about  saliva   testing   or  information   on   what  labs  to  request  when   talking   to  your  prescriber  feel  free  to  contact  us.  

We are here for you!

Looking for  an  easy   and  alterna;ve  approach  to  your  testosterone  replacement?  NaturalMed  Apothecary   is  your   answer.    Since  all  of   our  medica;ons  are  made   specifically  for   you,  we  are  able   to  work   closely   with  your  prescribing   physician  to  create  the  proper  dosage  form  and  strength   for  you.    If  you  are  looking  for   a  natural  “hormone   friendly”   doctor,  please  contact   us  for  a  referral  list.    We  find  most  insurance  companies  cover  testosterone  replacement.    You   may  also  use  your  flexible  spending  account  or  Health  Savings  Account.

DOSING MADE EASY! Forget about  dousing   yourself   in  a   half   jar   of   testosterone  for  you  to  notice  a  difference.    If   testosterone   replacement  is  an  option  for  you  we  have   many   dosing  options   to  fit  your  lifestyle!     From  topicals   to  rapid   dissolve  tablets  we  are  more  than  happy  to  accommodate  to  make  it  easy  and  cost  effective!

212 N.  Park  Avenue    |    Herrin,  IL  62948 (Located  directly  across  from  Bryan  Furniture  in  downtown  Herrin) Phone:    (618)  942-­‐6900    |    Toll  Free:    (877)  768-­‐7853    |    Fax:    (618)  942-­‐7600

Hours:  Monday  -­‐  Thursday:    8:30  a.m.-­‐  5:00  p.m.    |    Friday:    8:30  a.m.  -­‐  4:00  p.m. Closed  Daily  For  Lunch:    12:30  p.m.  -­‐  1:30  p.m.

Profile for NaturalMed Apothecary

Andropause & Low Testosterone  

What is andropause and what solutions can NaturalMed Apothecary offer you!

Andropause & Low Testosterone  

What is andropause and what solutions can NaturalMed Apothecary offer you!