The Research Front Several scientists affiliated with Providence Saint John’s Health Center have published notable research papers in recent months.
JUNE 27 JWCI Fellowship Graduation Private residence
JULY 4 Will Rogers 5K, 10K Run Pacific Palisades
OCT. 19 Providence Saint John’s Health Center Gala Beverly Hilton Hotel
For more information on these and other upcoming events, please contact Tess Csiszar at 310-829-8168 or Theresa.Csiszar@stjohns.org
Dave S.B. Hoon, PhD, professor and director of the department of translational molecular medicine at the John Wayne Cancer Institute (JWCI), is among the co-authors of a paper published in January in the journal Cell identifying a protein called ubiquilin-4 as a biomarker of genetic instability. The study, part of an international research collaborative that includes Tel Aviv University, found that ubiquilin-4 defends human DNA from damage, such as radiation or toxins in the air or food. However, too much ubiquilin-4 is harmful. In tumors, rising levels of the protein accelerate a tumor’s progression and make it resistant to cancer treatment. Measuring ubiquilin-4 may help doctors predict a patient’s response to chemotherapy or radiation.
Car Culture Valet and visitor parking rates have been increased at Providence Saint John’s Health Center. The adjustments were made because the former rates were below other parking fees in the area, leading people visiting other facilities to use the Saint John’s parking areas and reducing space for Saint John’s visitors.
SAINT JOHN'S MAGAZINE
Venkata Yenugonda, PhD, associate professor at the department of translational neurosciences and neurotherapeutics and director of the drug discovery and nanomedicine research program at JWCI, recently published a study showing that his proprietary, highly selective nicotine receptor desensitizing small molecule (a smoking cessation drug called VMY-2-95) can also decrease selfadministration of cocaine and methamphetamine in rat models. The drug and its analogs are promising candidates for development into treatments for a variety of addictions, such as tobacco, alcohol and stimulants. The study appears in the European Journal of Pharmacology.
46-60: 61-75: INCREASING 31-45: INCREASING FROM $9 TO $10 INCREASING FROM $11 TO $13 FROM $7 TO $8
THE NEW RATES: 16-30: INCREASING FROM $5 TO $6 0-15 MINUTES: STILL FREE
76-90: INCREASING FROM $13 TO $15 91 OR MORE: INCREASING FROM $16 TO $18