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Sodium dichromate (cas 10588-01-9) MSDS MSDS CAS SYNONYMS

:

Dichromic acid, disodium salt

: :

10588-01-9 * Bichromate de sodium * Bichromate of soda * Disodium dichromate * Natriumbichromaat * Natriumdichromaat * Natriumdichromat * Sodio (dicromato di) * Sodium bichromate * Sodium dichromate(VI) * Sodium dichromate * Sodium(dichromate de)

Catalog of Chemical Suppliers, Buyers, Custom Synthesis Companies And Equipment Manufacturers [ Dichromic acid, disodium salt 10588-01-9 ]

*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER

: HX7700000

CHEMICAL NAME

: Dichromic acid, disodium salt

CAS REGISTRY NUMBER

: 10588-01-9

LAST UPDATED

: 199806

DATA ITEMS CITED

: 52

MOLECULAR FORMULA

: Cr2-O7.2Na

MOLECULAR WEIGHT

: 261.98

WISWESSER LINE NOTATION : NA2 CR2-O7 COMPOUND DESCRIPTOR

: Tumorigen Mutagen Reproductive Effector Human

SYNONYMS/TRADE NAMES : * Bichromate de sodium * Bichromate of soda * Disodium dichromate * Natriumbichromaat


* Natriumdichromaat * Natriumdichromat * Sodio (dicromato di) * Sodium bichromate * Sodium dichromate(VI) * Sodium dichromate * Sodium(dichromate de)

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST

: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE

: Oral

SPECIES OBSERVED

: Human - child

DOSE/DURATION

: 50 mg/kg

TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1-

1959-

Volume(issue)/page/year: 22,291,1980

TYPE OF TEST

: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE

: Oral

SPECIES OBSERVED

: Human - child

DOSE/DURATION

: 250 mg/kg

TOXIC EFFECTS : Lungs, Thorax, or Respiration - cough Gastrointestinal - nausea or vomiting Skin and Appendages - sweating REFERENCE : AUPJB7 Australian Paediatric Journal. (Royal Childrens Hospital, Parkville, Vic., Australia) V.1-

1965- Volume(issue)/page/year: 21,65,1985

TYPE OF TEST

: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE

: Oral

SPECIES OBSERVED

: Rodent - rat

DOSE/DURATION

: 50 mg/kg

TOXIC EFFECTS : liver - other changes Kidney, Ureter, Bladder - other changes REFERENCE :


GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 22(8),38,1978

TYPE OF TEST

: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE

: Subcutaneous

SPECIES OBSERVED

: Rodent - rat

DOSE/DURATION

: 80 mg/kg

TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1-

1981- Volume(issue)/page/year: 4,75,1984

TYPE OF TEST

: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE

: Intravenous

SPECIES OBSERVED

: Rodent - mouse

DOSE/DURATION

: 26200 ug/kg

TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep. Ger.) V.1-5, 1975-76. Discontinued. Volume(issue)/page/year: 1,1,1975

TYPE OF TEST

: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE

: Intravenous

SPECIES OBSERVED

: Rodent - rabbit

DOSE/DURATION

: 18400 ug/kg

TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep. Ger.) V.1-5, 1975-76. Discontinued. Volume(issue)/page/year: 1,1,1975

TYPE OF TEST

: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE

: Administration onto the skin

SPECIES OBSERVED

: Rodent - guinea pig

DOSE/DURATION

: 335 mg/kg

TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1-

1960- Volume(issue)/page/year:


11,201,1965

TYPE OF TEST

: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE

: Intraperitoneal

SPECIES OBSERVED

: Rodent - guinea pig

DOSE/DURATION

: 335 mg/kg

TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1-

1960- Volume(issue)/page/year:

11,201,1965

TYPE OF TEST

: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE

: Subcutaneous

SPECIES OBSERVED

: Rodent - guinea pig

DOSE/DURATION

: 23 mg/kg

TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1330,1935

TYPE OF TEST

: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE

: Intravenous

SPECIES OBSERVED

: Amphibian - frog

DOSE/DURATION

: 196 mg/kg

TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.41898- Volume(issue)/page/year: 62,330,1939

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST

: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE

: Oral

SPECIES OBSERVED

: Mammal - dog

DOSE/DURATION

: 7280 mg/kg/2Y-C

TOXIC EFFECTS : Cardiac - changes in coronary arteries REFERENCE :


GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 19(6),35,1975

TYPE OF TEST

: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE

: Oral

SPECIES OBSERVED

: Mammal - pig

DOSE/DURATION

: 3438 ug/kg/39W-C

TOXIC EFFECTS : Cardiac - other changes REFERENCE : CUTOEX Current Toxicology. (Nova Science Publishers, Inc., 6080 Jericho Turnpike, Suite 207, Commack, NY 11725) V.1

1993-

Volume(issue)/page/year: 1,221,1993

** TUMORIGENIC DATA **

TYPE OF TEST

: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE

: Inhalation

SPECIES OBSERVED

: Rodent - rat

DOSE/DURATION

: 252 ug/m3/78W-I

TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors REFERENCE : TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1-

1973- Volume(issue)/page/year: 42,219,1986

TYPE OF TEST

: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE

: Intrapleural

SPECIES OBSERVED

: Rodent - rat

DOSE/DURATION

: 160 mg/kg/69W-I

TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors REFERENCE : AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1-

1960- Volume(issue)/page/year:

5,445,1962

** REPRODUCTIVE DATA **

TYPE OF TEST

: TDLo - Lowest published toxic dose


ROUTE OF EXPOSURE

: Intraperitoneal

SPECIES OBSERVED

: Rodent - rat

DOSE

: 20 mg/kg

SEX/DURATION

: male 8 week(s) pre-mating

TOXIC EFFECTS : Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - other effects on male Endocrine - androgenic REFERENCE : HETOEA Human & Experimental Toxicology. (Macmillan Press Ltd., Brunel Road, Houndmills, Basingstoke, Hampshire, RG21 2XS, UK) V.9- 1990Volume(issue)/page/year: 11,255,1992

** MUTATION DATA **

TYPE OF TEST

: Mutation in microorganisms

TEST SYSTEM

: Bacteria - Salmonella typhimurium

DOSE/DURATION

: 35 ug/plate

REFERENCE : CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1-

1980-

Volume(issue)/page/year: 9,611,1988

TYPE OF TEST

: Mutation in microorganisms

TEST SYSTEM

: Bacteria - Salmonella typhimurium

DOSE/DURATION

: 30 ug/plate

REFERENCE : PCBRD2 Progress in Clinical and Biological Research. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1-

1975- Volume(issue)/page/year:

109,453,1982

TYPE OF TEST

: DNA repair

TEST SYSTEM

: Bacteria - Bacillus subtilis

DOSE/DURATION

: 50 mmol/L

REFERENCE : TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1-

1977- Volume(issue)/page/year: 7,439,1981

TYPE OF TEST

: Mutation in microorganisms

TEST SYSTEM

: Bacteria - Escherichia coli

DOSE/DURATION

: 5 ug/plate

REFERENCE :


MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1-

1964- Volume(issue)/page/year: 412,17,1998

TYPE OF TEST

: DNA repair

TEST SYSTEM

: Bacteria - Escherichia coli

DOSE/DURATION

: 200 nmol/plate

REFERENCE : JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1-

1975/76-

Volume(issue)/page/year: 9,287,1982

TYPE OF TEST

: DNA repair

TEST SYSTEM

: Bacteria - Bacillus subtilis

DOSE/DURATION

: 50 mmol/L

REFERENCE : TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1-

1977- Volume(issue)/page/year: 7,439,1981

TYPE OF TEST

: Cytogenetic analysis

TEST SYSTEM

: Human Lymphocyte

DOSE/DURATION

: 2 umol/L

REFERENCE : CARYAB Caryologia. (Via G. LaPira 4, 50121 Florence, Italy) V.1-

1948-

Volume(issue)/page/year: 33,239,1980

TYPE OF TEST

: Morphological transformation

TEST SYSTEM

: Rodent - rat Cells - not otherwise specified

DOSE/DURATION

: 300 nmol/L

REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1-

1964- Volume(issue)/page/year: 198,115,1988

TYPE OF TEST

: DNA damage

ROUTE OF EXPOSURE

: Intraperitoneal

TEST SYSTEM

: Rodent - rat

DOSE/DURATION

: 20 mg/kg

REFERENCE : JBCHA3 Journal of Biological Chemistry. (428 E. Preston St., Baltimore, MD 21202) V.1-

1905- Volume(issue)/page/year: 256,3623,1981

TYPE OF TEST

: DNA damage

TEST SYSTEM

: Rodent - rat Liver

DOSE/DURATION

: 300 umol/L

REFERENCE :


MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1-

1964- Volume(issue)/page/year: 189,69,1987

TYPE OF TEST

: DNA damage

TEST SYSTEM

: Rodent - rat Cells - not otherwise specified

DOSE/DURATION

: 500 umol/L

REFERENCE : FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20-

1982- Volume(issue)/page/year:

31,271,1993

TYPE OF TEST

: Cytogenetic analysis

TEST SYSTEM

: Rodent - hamster Ovary

DOSE/DURATION

: 250 ug/L

REFERENCE : TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1-

1973- Volume(issue)/page/year: 17,219,1980

TYPE OF TEST

: Sister chromatid exchange

TEST SYSTEM

: Rodent - hamster Ovary

DOSE/DURATION

: 250 ug/L

REFERENCE : TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1-

1973- Volume(issue)/page/year: 17,219,1980

*** REVIEWS ***

ACGIH TLV-TWA 0.05 mg(Cr)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997

ACGIH TLV-Confirmed human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997

IARC Cancer Review:Human Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1-

1972- Volume(issue)/page/year: 49,49,1990


IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1-

1972- Volume(issue)/page/year: 23,205,1980

IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1-

1972- Volume(issue)/page/year: 49,49,1990

IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1-

1972- Volume(issue)/page/year: 2,100,1973

IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1-

1972- Volume(issue)/page/year: 23,205,1980

IARC Cancer Review:Group 1 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1-

1972- Volume(issue)/page/year: 49,49,1990

TOXICOLOGY REVIEW FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 9,105,1971

TOXICOLOGY REVIEW 85DHAX "Medical and Biologic Effects of Environmental Pollutants Series," Washington, DC, National Academy of Sciences, 1972-77 Volume(issue)/page/year: Cr,22,1974

*** U.S. STANDARDS AND REGULATIONS ***

EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1-

1936- Volume(issue)/page/year:

54,7740,1989

MSHA STANDARD-air:TWA 0.5 mg(Cr)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices


(BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,35,1971

OSHA PEL (Gen Indu):CL 0.1 mg(CrO3)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994

OSHA PEL (Construc):CL 0.1 mg(CrO3)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994

OSHA PEL (Shipyard):CL 0.1 mg(CrO3)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993

OSHA PEL (Fed Cont):CL 0.1 mg(CrO3)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO CHROMIUM(VI)-air:10H CA TWA 0.001 mg(Cr)/m3 REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M0073 No. of Facilities: 7838 (estimated) No. of Industries: 85 No. of Occupations: 64 No. of Employees: 44269 (estimated)

NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M0073 No. of Facilities: 11523 (estimated)


No. of Industries: 118 No. of Occupations: 82 No. of Employees: 136313 (estimated) No. of Female Employees: 24542 (estimated)

*** STATUS IN U.S. ***

EPA GENETOX PROGRAM 1988, Positive: Histidine reversion-Ames test

EPA TSCA Section 8(b) CHEMICAL INVENTORY

EPA TSCA Section 8(d) unpublished health/safety studies

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

NTP 7th Annual Report on Carcinogens, 1992 : known to be carcinogenic

*** END OF RECORD ***


Sodium dichromate (cas 10588-01-9) MSDS  

Sodium dichromate (cas 10588-01-9) MSDS

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