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Annual report 2011 Steno Diabetes Center


Table of contents

Table of contents 5

From the Director

9

Clinical Activities

15

Biomedical Research

21

Health Promotion Center

27

Education

31

Outreach and Consultation Activities

35

Business Support

41

Awards, Dissertations, Publications

3


From the Director

By John J. Nolan

From the Director

5


From the Director

From the Director The past year has been a period of strategic

range of European partners. This was an important

transition

The

milestone for research at Steno. Each project is

organization is focused around the activities of the

focused on prevention (prevention of progression

four centers who are working closely together on

to type 2 diabetes; prevention of progression

translational research, treatment, and prevention:

of the earliest stages of renal complications of

Patient Care, Research, Health Promotion, and

diabetes) directly in line with our strategic focus.

and

development

for

Steno.

Education. This configuration allows Steno to focus on the complete spectrum of diabetes from

The coming year will not be without challenges,

earliest risk through to long-standing diabetes

but we will strive to maintain our status as a world-

with complications, while ensuring that results are

leader within diabetes treatment and prevention

directly implemented to improve patient care and

and aim to strengthen further our national and

management as well as targeting new approaches

international partnerships and collaborations.

to disease prevention. I would like to extend my appreciation to all the An important milestone in 2011 was the development

staff at Steno, to our collaborating partners, to

and launch of the Steno 2020 Aspiration Strategy.

the Steno Management team, and to our Board of

The strategy actively contributes to the fulfilment

Directors for their support. Finally, I would also

of Steno’s vision which is characterised by Superior

like to extend my thanks to our Patient Panel and

quality of care, Full-cycle care and prevention,

to all the patients at Steno who have been and will

Global presence and recognition, and People and

continue to be the focus of our efforts and goals

organisational development. These cornerstones

for the future.

anchor our overall focus, while also ensuring that we are creating an inspiring, productive work environment.

In late 2011, the EU Seventh Framework Programme (FP7) awarded Steno Diabetes Center with two major research consortium grants totalling 11 million Euros. The grants (DEXLIFE and PRIORITY) will run over the next 3-5 years and involve a wide

6

John J. Nolan, MD FRCPI FRCP(Ed) Director and CEO


From the Director

Aspiration strategy 2020

Superior quality of care

Full-cycle care and prevention

We will excel in clinical care

We will develop solutions for both

through our clinics, the use

care and prevention of diabetes

of modern technologies, and improved methods for patient education.

through research in health promotion, understanding of early disease, complications and novel approaches to clinical care.

Global presence and recognition We will extend Steno’s educational message through

People and organisational development We will develop Steno’s

local Steno hubs in high-

organisation through leadership,

prevalence countries, as well as

attraction and retention of talent

through web-based approaches and through international

and a culture marked by the joy of high performance.

research partnerships.

7


Clinical Activities

Clinical Activities

9


Clinical Activities

Clinical Activities The Patient Care Center at Steno was established in 1932 and was dedicated to the treatment of patients with diabetes and to investigate and gain knowledge on diabetes treatment. This is still the

Fig. 1 - Patient population at Steno In 2011, Steno had around 6000 patients in total and of these, 740 were new patients.

case and Steno has developed into a large outpatient clinic with expert knowledge on diabetes patient management and care.

The patient base is primarily from the Capital region of Copenhagen (90%). The center serves as an integrated part of the public health care system

2300

and is under contract with the Capital region. The remaining 10% of patients seen at the center are

3700

referred from other regions of Denmark.

The clinical staff of 90 in the center includes doctors, nurses, dieticians, secretaries, podiatrists, and

lab

technicians.

The

clinical

services

offered include eye screening, which is closely linked with the Capital Regions Department of Ophthalmology, and a podiatry services including

Type 1 diabetes

Type 2 diabetes

an external orthopedic consultant. These expertise areas, together with dieticians and lab technicians, ensure optimal treatment and consultation for all patient management issues.

if the treatment goals are met, the patients are referred to their own doctor.

Patient care at Steno includes both type 1 and type 2 diabetes patients. Type 1 patients are followed lifelong at Steno. Patients with type 2 diabetes are referred from general practitioners for work-up including screening for complications, diabetes education, and optimizing of the medical treatment. This usually lasts from 6–8 months and

10

Steno has operated a completely electronic medical record system since 2001, strongly enhancing team-based patient care, and supporting quality assurance and audit.


Clinical Activities

Fig. 2 - Outpatients at Steno Steno Diabetes Center has team-based patient care where patients can receive care of feet and eyes, get dietary advice, and a general check-up in one visit. Steno conducts over 20.000 outpatient visits a year including 10,000 physician visits as well as the following consultations:

4000 3200 2000 500 380

Table 1 - Steno’s performance over the last 3 years In order to ensure a high quality of patient treatment and management, Steno uses the National Committee of Quality Assurance (NCQA) system as a reference.The below table outlines Steno’s performance over the last 3 years and compared to the NCQA standard.

NCQA Standard

2009

Type 1 diabetes Type 2 diabetes

2010

2011

HbA1c > 9,0 %

≤ 15%

20.8

21.1

22.2

21.6

20.8

19.9

HbA1c < 7,0 %

> 40%

14.3

23.9

14.2

23.9

15.5

25.4

HbA1c < 8,0 %

> 60%

46.3

54.3

45.5

55.3

49.0

56.7

BP > 140/90

≤ 35%

7.9

9.1

6.6

8.4

7.2

8.5

BP < 130/80

> 25%

29.2

28.5

29.5

26.0

30.4

25.5

Eyes screenings

> 60%

69.9

74.1

67.1

68.7

66.0

68.4

Smoking status assessed

> 80%

46.9

50.3

52.2

53.9

93.7

93.1

LDL chol > 3,3 mmol/l

≤ 37%

10.2

6.8

13.6

8.6

15.3

9.4

LDL chol < 2,6 mmol/l

> 36%

64.2

80.9

57.8

74.0

52.1

73.2

Renal assessment

> 80%

90.9

96.0

91.3

95.2

91.9

96.5

Feet examined

> 80%

68.4

71.7

80.0

83.3

84.2

85.7

HbA1c: Glycated haemoglobin (average plasma glucose concentration)

BP: Blood Pressure

LDL Chol: LDL Cholesterol

11


Clinical Activities

Clinical Biochemical and Physiology Lab The Patient Care Center includes a Clinical

EN ISO 15189:2008) and the iLAC (International

Biochemical and Physiology Lab which provides

quality example).

biochemistry service to the outpatient clinic as well as diabetes relevant clinical physiology

As an integrated part of the lab, lab technicians train

investigations.

patients in using blood glucose measurements. Patients can also have their devices checked as

The lab is accredited under the Danish DANAK

well as to take their own blood pressure at home

organization

with standardized equipment from the lab.

(Standard

of

Accrediation:

DS/

Fig. 3 - Standard of Accrediation The activity in the biochemistry department totaled 360,000 investigations. The graph contains an overview of the analysis performed in 2011, including the consulting activity provided by the lab.

12


Clinical Activities

Research in the Patient Care Center The research run directly by the staff of the

are collaborating on other projects addressing

outpatient clinic is closely related to improvement

education and treatment of type 2 diabetes and

of treatment quality. In 2010 and 2011 these

research aiming to optimize the use of social

projects focused on ways and methods of reducing

networks for patients with type 1 diabetes.

HbA1c among patients with HbA1c above 75 mmol/mol (9 %). Additionally, staff from the clinic

Table 2 - Active projects in 2011 Patients seen in the outpatient clinic are also offered participation in various clinical research projects. The active projects in 2011 included:.

Title

Improvement of poorly controlled diabetes in younger adults through Guided Self Determination

Number of patients enrolled

200

Does use of periodical Continous Glucose Measurement (CGM) improve HbA1c in poorly regulated type1 diabetes patients (Adult and Adolescent)

160 Adult 20 Adolescent

Improvement of blood glucose control in patient with foot ulcers

60

13


Biomedical Research

Biomedical Research

15


Biomedical Research

Biomedical Research Complications Research group

The group is also partnering on another EU-

It is our ambition that patients with diabetes will live longer lives without complications. Over the past year, the group has worked to combine our interest in new biomarkers for early detection of diabetic complications, such as renal and cardiovascular complications, with our experience in preventing and treating diabetic renal disease.

funded project, SYSKID (Systems Biology in Kidney disease). The objective of this project is to study different new techniques for measurement of genetic and non-genetic markers and see if combining them provides an overview of the mechanisms leading to chronic kidney diseases, the dominating cause of renal failure in the Western world.

Together with an international collaboration of 15 European partners, the group has developed a study where patients with an elevated risk for future renal disease are identified with a new urinary proteomic analysis, developed by one of the partners, and are randomized to aldosterone blockade or placebo in addition to usual treatment. The study, called PRIORITY (eu-priority.org) was funded by the European Commission in December 2011 and will be coordinated by Steno.

Studies with biomarkers such as vitamin D and uric acid have suggested that these markers are also of relevance and may provide new targets for optimized treatment which the group is exploring further in current and future studies. Although one single marker may provide insight into disease pathophysiology,

the

combination

of

many

markers may provide even better information for greater understanding and prognostic impact.

16

Even the right clinical treatment will not work if patients are not taking their medication. Therefore, in collaboration with the epidemiology group and the Health Promotion Center at Steno, the complications group is trying to unravel the challenges related to improving patient adherence.


Biomedical Research

Priority Study - European Commission in December 2011 at Steno Diabetes Center

Epidemiology Research The main achievement for the Epidemiology group in 2011 was the conclusion of the clinical examinations in the ADDITION-PRO study. This study follows participants who were found to have elevated diabetes risk or impaired glucose regulation between 2001 and 2006. The followup examination allowed us to assess how many had progressed to diabetes in the meantime, and what their diabetes and cardiovascular risk status was. Between 2009 and 2011, 2143 participants were seen at Steno and in 3 different centres in Jutland. There are four ongoing PhD projects

A second research line in the Epidemiology group is register-based research. A clear highlight in this area in 2011 was the publication in Diabetologia of a paper describing the occurrence of different types of cancer among patients with diabetes according to their insulin use status. This study was based on linkage of the Danish diabetes register and the Danish cancer register and showed that the association between insulin use and cancer is strongest at the point of therapy initiation and tapers off in the subsequent years. The project continues and will look more precisely into dosage and insulin subtypes.

based on ADDITION-PRO, focusing on central fat distribution, arterial stiffness, physical activity and

The group worked in close collaboration with Novo

proteomics.

Nordisk and the Steno Patient Care Center on the

17


Biomedical Research

Diabetes World Tour project, which evaluated the occurrence of undiagnosed diabetes and undetected cardiovascular risk and retinopathy among over 8,000 individuals in the United Arab Emirates, Saudi Arabia, Algeria, and Portugal.

In 2011 the Epidemiology group contributed to 50 publications, with 7 of those in journals with an

Fig. 4 - Clinical Research Unit activities The activities at the clinical research unit are divided into three areas: Investigator initiated intervention studies, Pharmaceutical initiated intervention studies, and observational studies. We have the expertise in-house to coordinate every aspect of single and multi-center trials from concept development to protocol design, execution, close-out, and data analysis.

impact factor greater than 7. Fifteen of the articles included a group member as first or last author. Group

members

taught

different

audiences,

ranging from undergraduate students in Denmark

Pharmaceutical Studies

to diabetologists in India. Teaching occurred at 16 sites in 6 countries. The group supervised ongoing projects from 8 Masters and PhD students. There were 28 poster and oral presentations at 16 conferences and meetings.

Observational Studies

Investigator-initiated Studies

Clinical Research The vision for the Clinical Research Unit (CRU) is to facilitate collaboration between internal research groups at Steno and external research collaborators. We strive to create and maintain an

infrastructure

based

on

superior

quality

and efficiency â&#x20AC;&#x201C; in patient care, in our working environment, and in research data collection and analysis. Our ultimate goal is to promote and expand the expertise around patient oriented clinical research at Steno Diabetes Center and in Denmark.

18

Our collaborators include Danish and International diabetes

researchers,

14

pharmaceutical

companies, Good Clinical Practice units at the surrounding Universities, several national and international

Clinical

Research

Organisations

(CROs), and external laboratories and pharmacies.


Biomedical Research

The Clinical Research Unit at Steno consists of 3 medical doctors, 6 nurses, 6 lab technicians, and 2 study coordinators.

The

realm

of

all

Our next steps, together with the Patient Care

aspects of diabetes treatment and prevention

Center and other Steno researchers, will take us

with

of

further into exploring the interaction between

focus

glycaemia

in

studies

areas type

executed

such 1

as:

and

include

Treatment

diabetes;

artery and bone mineralisation and the major

Understanding and preventing hypoglycaemia;

challenge of obstructive sleep apnea, which seems

Cardiovascular

to be present in every third patient with type 2

disease

type

and

2 risk

factors;

Neuropathy; and, Obstructive sleep apnea.

diabetes referred to Steno Diabetes Center.

19


Health Promotion Center

Health Promotion Center

21


Health Promotion Center

Health Promotion Center Steno Health Promotion Center, launched in

3. Development of people’s competence to

June 2009, has three overall focus areas: Patient

take action and control their own life as

education, prevention, and health promotion.

well as their living conditions

The center aims at establishing cross-disciplinary

4. Acknowledging the context in which

cooperation with partners at Steno as well as with

people live and to include this in the

external institutions in Denmark and abroad. The

intervention carried out

focus is on research with a potential to influence “real life” practices.

Research at the Steno Health Promotion

5. Increasing equity in health by paying attention also to the least resourceful members of the community

Center is based on five principles: During 2011 more than 15 different projects have 1. Active involvement of the target group as a basis for development of ownership and sustainable health promoting change 2. A positive and broad concept of

22

been initiated. Due to this increase of activity and substantial external funding during 2011, the number of overall staff is now at 35, covering a broad range of academic fields such as public

health, which focuses on the person as a

health,

anthropology,

psychology,

whole instead of just the disease

social science and design.

pedagogy,


Health Promotion Center

Health Promotion

Steno plays an active role in the World Diabetes

Research regarding this focus area included

Foundation

funded

Vida

Nueva

project

on

gestational diabetes in Barranquilla, Colombia.

the following activities in 2011: • Pre-diabetes – prevention among people at risk

Collaborating together with local health authorities and three local universities, along with the HJELT Institute at the University of Finland, the project

• Gestational diabetes • Schools and families as health promoters

aims to detect and manage gestational diabetes and develop compatible research projects.

The research field of pre-diabetes is focused on finding real-life diet and exercise interventions

The health promotion projects on young

to prevent type 2 diabetes. In collaboration

people, families and schools are centered

with colleagues at University of Aarhus, Steno conducted

a

pilot

project

among

general

practitioners in Denmark. The results identified a number of limitations to this approach which will allow us to explore alternative approaches in settings such as municipality prevention centers and local communities.

around the following approaches: 1. use of innovative technologies and aesthetic learning processes; 2. use of cultural meetings 3. collaboration between schools and communities

Project ”PULSE” In 2011, the Novo Nordisk Foundation funded a new collaborative project between Steno and the Experimentarium in Copenhagen. The project, called PULSE, focuses on family interaction and education as a key component for improved health. The activities will focus on children and young people as being

PULSE Innovative health promotion exhibitions engaging families: A cross-disciplinary development and research project

the catalysts for change in the family and community at large. The project collaborators include Kenyatta University, Roskilde University, the Municipality

of Gentofte, the University

of Southern Denmark, and The University of Copenhagen.

A pulse is rhythmical, a beat of the heart, a movement. PULSE is an innovative research-based exhibition concept combining state-of-the-art exhibition methodologies and health promotion. The name PULSE reflects the exhibition’s goals of learning, fun and improving health.

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Health Promotion Center

Patient Education

• Development of health educational

Research on patient preferences, psychosocial health,

social

network,

social

support

and

diabetes related behaviors inform all other areas

interventions in the Type 2 Clinic at the Steno Patient Care Center • Use of innovative and participatory methods in consultations concerning medical

of research for patient education. The focus in

compliance among type 2 patients with poor

2011 has been on participation, dialogue and the

glycemic control

development of competences among diabetes

• Psychosocial health and diabetes

patients. Research has also been conducted on the

• Educational activities for HCPs, policy makers,

learning processes, theories and methods among

decision makers and others working within

health care professionals engaged in participatory

the field of diabetes

patient education. Next Steps: During 2012 the focus will be to

In 2011 the Patient Education research

test and further revise the tools developed for

activities included:

participatory patient education and to establish

• Survey on patients’ preferences, social

and consolidate the research area of psycho-

network, activation and perceptions of

social dimensions of diabetes.

perceived care

Tools for patient education Tools developed in 2011 for implementation in clinical settings, available online at www.steno.dk

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Health Promotion Center

Prevention

This approach received external funding from

In 2011 research in prevention included the

the Nordea Foundation for implementation on the Danish island of Bornholm. The objective of

following areas: • Work place and work force health promotion • Supersettings as a new prevention approach in local communities

the 4-year project will be to facilitate a healthy life among families with small children through a synergetic partnership between media (TV2 Bornholm),

In the area of workplace one focus point has been on a literature review, exploring the main literature for the last 30 years with a specific focus on technology and health promotion, behavior approaches and leadership and health promotion.

local

supermarkets,

schools,

and

daycares. The project is a collaboration with the Capital Region’s Research Centre for Health and Prevention, the research group MENU at Aalborg University, the municipality of Bornholm, local NGO’s and Steno.

The review was one of the cornerstones in Health

During 2012 the focus for the group will be to

Promotion – do we need an upgrade” organized

develop and test the intervention approach within

in collaboration with the National Research

the Bornholm supersetting project and to initiate

Centre for the Working Environment.

similar projects in two other Danish municipalities

the

international

seminar

“Workplace

One of

the outcomes of this seminar was to establish an

(Odsherred and Vejle).

international workforce health promotion research network which is a collaboration between Steno, the National Research Centre for the Working Environment, and Copenhagen Business School.

Steno

is

also

collaborating

with

selected

communities in developing new and innovative solutions that are referred to as supersettingapproaches. A supersetting implies broad, crosssectoral collaboration and ownership as well as long-term commitment, context-sensitivity, and evidence-based decision making.

25


Education

Education

27


Education

Education Through education of endocrinologists, diabetes teams, and other health care professionals (HCP) Steno Education Center is disseminating the

developing countries. The courses were held in China, India, and Turky (600 participants). • A newly-developed course in quality

clinical competencies, front-line research results,

assurance of clinical data in diabetes was held

and patient focused treatment and care practices

in India (60 participants).

from Steno.

Performed through state-of-the-art knowledge sharing at seminars, symposiums, and workshops,

• Two international courses in Practical Diabetology hosted in Denmark (100 participants). • One international course on nursing in the near east (80 participants).

the teaching faculty is a multidisciplinary diabetes team from Steno Diabetes Center, ensuring that all key core competencies necessary for optimal treatment of diabetes are covered.

National courses: • A course for general practitioners held in collaboration with the Danish medical association

Steno Education Center conducts educational programs on: • Team based diabetes management drawing on Steno Diabetes Center’s expertise and

• Two nurse-led courses in collaboration with the University College of Sjælland. • Several nurse courses for Danish nurses in primary health care.

experience • Updates and symposiums on diabetes management and frontline diabetes research

Next Steps: The future focus areas for the Steno Education Center will be building international

• Nurse-led practical diabetes course for HCP

HUBs for teaching locally, developing e-learning

• Clinical quality assurance programs for

programs to ease accessibility, as well as continuing

diabetes clinics using the unique Steno

our collaboration with local partners on quality

Quality Assurance Tool (SQAT)

assurance of clinical care to enhance patient care and management of diabetes globally.

Activities in 2011 included: International courses: • Frontiers symposium in Copenhagen (170 participants). • Eight Steno Training and Application of Resources (STAR) courses for education in

28


Outreach and Consultation Activities

Outreach and Consultation Activities

31


Outreach and Consultation Activities

Outreach and Consultation Activities Activities in 2011

The Danish Society for Endocriniology, Chairman-elect

Peter Rossing, MD, DMSc

Danish National Indicator Project, Chairman

Peter Rossing, MD, DMSc

Advisory Board on Health Promotion, Danish Prevention Foundation

Bjarne Bruun Jensen, PhD

Danish Guidelines for Treatment of Type II Diabetes, Member

Peter Rossing, MD, DMSc

World Health Organization, Development of “Health 2020,” Advisor

Bjarne Bruun Jensen, PhD

University College Metropol, Copenhagen, Board of Directors

Bjarne Bruun Jensen, PhD

Capital Region Advisory Board for Diabetes, Member

Thomas Almdal, MD, DMSc

Capital Region advisory Board for Endocrinology, Member

Thomas Almdal, MD, DMSc

National Prevention and Health Promotion Council, Member

Board of the Danish Hypertension Society, Member

EURADIA task force to develop European Platform for Clinical Research in Diabetes, Chairman

32

Responsible

Ingrid Willaing, PhD

Peter Rossing, MD, DMSc

John J. Nolan, MD FRCPI FRCP(Ed)


Outreach and Consultation Activities

Steno Symposium May 2011

Participation and dialogue in patient

160 doctors from 26 countries attended the

education

Steno Symposium from 25th-27th of May 2011,

On 29th November, Steno Health Promotion Center

which focused on the latest research within early

and the Danish Association for Nurses hosted

detection, prevention, and treatment of diabetes

a conference focused on patient education and

complications.

communication around chronic diseases such as diabetes. More than 300 researchers and other

The symposium, which ran over 2 days, had a

health professionals attended the conference

program focusing on clinical research that can

in Copenhagen to share knowledge and best

be easily applied in daily practice. The theme

practices on ways to improve participation and

throughout the program was prevention and

dialogue in patient education.

detection of complications, as early as possible,

Theatre and Health Promotion among

with the use of existing and new methods.

Children EUPHA meeting with Copenhagen School of

A two-day international symposium on â&#x20AC;&#x153;Theatre

Global Health

as a Setting for Health Promotion among Childrenâ&#x20AC;?

On 10 November Steno Health Promotion Center

was hosted by Steno in December 2011. The

and

Health,

symposium brought together 30 researchers and

University of Copenhagen, hosted a pre-conference

practitioners in order to explore the potential of

session in connection with the European Public

this new field and to plan for future collaboration.

Copenhagen

School

of

Global

Health Conference (EUPHA). The themes focused on the social determinants influencing prevention and control of non-communicable diseases and the research needed to support these.

33


Business Support

Business Support

35


Business Support

Business Support Fig. 5 - External funding 2011 Steno has been extremely successful in 2011 to attract external funding to support research activities. This funding has been obtained from public and private grant awards based on applications for research projects and network and collaborations.

Funding

Focus on Quality

In 2011, Steno Diabetes Centerâ&#x20AC;&#x2122;s total funding

Quality is a key focus area at Steno and as a

was DKK 176 million (EUR 23.7 million) stemming

consequence we highly prioritise developing and

from three major sources: The Capital Region

anchoring our Quality Management System. We

of Copenhagen, The Novo Nordisk Foundation,

are committed to continuously measure, evaluate

and Novo Nordisk A/S. The majority of funding

and adjust our performance in our ambition to

from these three sources is governed by fixed

meet the highest standards. This not only relates

contracts ensuring the operation of patient care,

to meeting end-points in standards for diabetes

educational activities, research activities, as well

care but that quality is part of everything we do.

as administrative support functions. As recognition of our efforts, we are proud to announce that in November 2011, we were awarded an accreditation according to the Danish Health Care Quality Programme (DDKM) by IKAS.

36


Business Support

Table 3 - Major foundings sources 2011 Overview of major funding sources and type of projects at Steno in 2011:

Grant

Title

Role

Duration

EU FP7

DEXLIFE Mechanisms of prevention of type 2 diabetes by lifestyle intervention in subjects with pre-diabetes of at high-risk for progression,

Coordinator

2012-2015

EU FP7

PRIORITY Proteomic prediction and Renin angiotensin aldosterone system Inhibition prevention Of early diabetic nephRopathy In TYpe 2 diabetic patients with normoalbuminuria,

Coordinator

2012-2017

EU FP7

SysKID, Cellular and molecular mechanisms of the development of chronic kidney disease,

Partner

2009-2014

The Danish Government (Southern Region)

Developing methods for patient education across diagnosis and in development of competence of health professionals,

Principal Investigator

2010-2012

The Danish Ministry of Health

Self-management and care for young adults with poorly regulated type 1 diabetes,

Principal Investigator

2009-2012

Danish Heart Association

Researching methods for communicating healthy lifestyles to children and adults,

Principal Investigator

2010-11

Danish Heart Association

Researching insights on young people’s understanding of health and risk factors,

Principal Investigator

2010-11

The City of Copenhagen

Evaluation of the city’s prevention efforts focused on the health of over-weight children,

Principal Investigator

2012-2013

Lundbeck Foundation

LUCAMP, Centre for Applied Medical Genomics in personalised disease prediction, prevention and care,

Partner

2009-2013

Novo Nordisk Foundation

PULSE: ”Innovative health promotion exhibitions engaging families: A cross-disciplinary development and research project,”

Partner

2012-2016

Nordea Foundation

Supersetting project, Bornholm

Partner

2011-2015

37


Business Support

Fig 6 - Headcount 2011, by contract type

People Steno

Diabetes

A large number of employees join Steno on a Center

currently

has

272

employees, of which 57 (21%) are externally affiliated. There was an overall growth in 2011 of 7,5% (within all employee groups) and this was

limited-time basis, typically to write PhD theses or for clinical or project rotations. To a large extent, this employee group has been and will continue to be a talent pipeline for Steno.

generally attributed to expanding the qualitative research areas and the introduction of new core

There are 18 managers at Steno Diabetes Center, of

functions.

which six are members of the management team. The past year saw a number of new initiatives

Steno Diabetes Center is a stable organization with very low employee turnover (average unwanted separation equals 0,8% of average permanent staff) and a high degree of employee engagement. In 2011, the average score on the annual employee satisfaction survey (eVoice) was 4,23 on a fivepoint scale, which indicates a strong commitment.

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regarding the alignment of people processes, leadership and talent development introduced by linking people and organizational development to the overall strategy, planning for implementation of Performance Management, and building a leadership development platform.


Awards, Dissertations, Publications

Awards, Dissertations, Publications

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Awards, Dissertations, Publications

Awards, Dissertations, Publications Awards Steno ranked as 39th best research institution in the world Steno Diabetes Center was ranked as the 39th best research institution in the world and the second best in Denmark by the world-renowned Scimago Institutions Rankings (SIR). The report, made public in December 2011, is the most comprehensive ranking of research institutions.

42

It

covers

institutions

with

more

than

100

publications and includes in total 3042 institutions that together are responsible for more than 80% of worldwide scientific output. The Excellence Rate indicates which percentage of an institutionâ&#x20AC;&#x2122;s scientific output is included into the set formed by the 10% of the most cited papers in their respective scientific fields. The ranking documents the high quality of research performed at Steno.


Awards, Dissertations, Publications

“Best Poster Award” at EASD For the second year in a row, a researcher at Steno won the best poster award at the 47th EASD (European Association for the Study of Diabetes) Annual Meeting in Lisbon, 12-16 September 2011. The poster, by Ingrid Wallaing, was entitled ”Patients with type 2 diabetes prefer education based on participation and development of competences over information”.

PhD theses

Master’s Degree Dissertations

1. Louise Lundby Christensen, MD: Carotid

1. Maiken Bang Hansen: Causes of Death among

intima-media thickness in type 2 diabetes – metholdological considerations and effects of interventions. University of Copenhagen, June 2011. 2. Kasper Ascanius Pilgaard, MD: Developmental Programming of Type 2 Diabetes. Novel Epidemiological and Mechanistic Insights from Danish cohort Studies. University of Copenhagen, June 2011.

Diabetes Patients. University of Copenhagen. 2. Stine Byberg: Sleep Duration and Markers of Glucose Homeostasis. University of Copenhagen. 3. Stine Kolind Krogsgaard. Repeatability and reproducibility of two measurements of arterial stiffness: Pulse wave velocity and augmentation index. University of Copenhagen.

3. Martin Friedrichsen: Is insulin resistance related to molecular events in skeletal muscle? – Integrative analyses of insulin signaling and inflammation. University of Copenhagen, June 2011. Professor Jørn Nerup, DMSc, Steno Diabetes Center, Gentofte, Denmark. 2011 4. Bruselius-Jensen, M. The poetic perspective of school lunches—the possibility of involving children in school meals. Roskilde University.

43


Awards, Dissertations, Publications

Publications Steno published over 80 peer-reviewed articles in 2011. Please visit www.stenodiabetescenter.com for a complete list and the link to pub med.

Fig 6 - Number of publication by impact factor 2008-2011

44


Awards, Dissertations, Publications

Fig 7 - Number of Publications by Year

45


Steno Diabetes Center is a world leading institution within diabetes care and prevention. Steno is owned by Novo Nordisk A/S and is a not for profit organisation working in partnership with the Danish healthcare system. Steno treats around 6000 people with diabetes.


2011 Steno Annual Report 15 March