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To be presented by:

Professor Yildiz Bayazitoglu Harry S. Cameron Chair Professor Department of Mechanical Engineering and Materials Science Rice University, Houston, Texas, USA April 3, 2013 4:10 – 5:00 p.m. Room 202, CAIN Mechanical Engineering Building Texas A&M University

Professor Yildiz Bayazitoglu joined Rice University in 1977, and, since 1996, has been Harry S. Cameron Chair Professor of Mechanical Engineering. Previously, she was an assistant professor at the Middle East Technical University in Turkey (1973-74) and was a visiting assistant professor at the University of Houston (1975-76). Professor Bayazitoglu received her bachelor's degree in mechanical engineering at the Middle East Technical University (Ankara, Turkey) in 1967, and her master's and doctoral degrees at the University of Michigan, Ann Arbor, in 1969 and 1974, respectively. She was the first woman to earn a Ph.D. degree in mechanical engineering from the University of Michigan. Professor Bayazitoglu has made significant contributions to thermophysical property determination and Professor Yildiz Bayazitoglu containerless processing of materials, radiation and convective heat transfer, phase-change heat transfer, oil reservoir fluid flow heat transfer, cryogenic tank thermal analysis, hydrogen-oxygen fuel cells, solar collector analysis, micro and nano scale heat transfer, and thermal modeling of the human head, nanoparticle assisted cancer therapy and hypothermic therapies. Professor Bayazitoglu has published extensively, and has co-authored two textbooks --- “Elements of Heat Transfer” (McGraw Hill; 1988), which has been translated into Korean, and “A Textbook for Heat Transfer Fundamentals” (Begell House; 2012). Currently, she is the Editor-in-Chief of Americas of the International Journal of Thermal Sciences (Elsevier). In 2012, Professor Bayazitoglu was elected an Honorary Member of the American Society of Mechanical Engineers (ASME), and received the Society of Women Engineers (SWE) Achievement Award, which is the highest award given by SWE. In 2004, she received the ASME Heat Transfer Memorial Award. Her other honors include the SWE Distinguished Educator Award, and, from Rice University, the George R. Brown Superior Teaching Award, the Outstanding College Associate Award, the Hershel M. Rich Outstanding Invention Award, the Graduate Student Association Teaching/Mentoring Award, the Julia Mile Chance Teaching Prize, the Faculty Impact Award, and the Presidential Mentoring Award. Professor Bayazitoglu is a Fellow of ASME, a Fellow of the American Association of Advancement of Science (AAAS), an Associate Fellow of the American Association of Aeronautics and Astronautics (AIAA). She has served as the chair of the ASME Heat Transfer Division, and has served on the executive committee of International Center of Heat and Mass Transfer (ICHMT).

Fowler Distinguished Lecture “Nanoparticle Assisted Radiation Interactions: Thermal Therapy� Since the near infrared spectrum is the region of highest physiological transmisivity, it is the optical communication gateway for the laser energy to propagate into the human body. This optical window also leads to nanoparticle assisted Photo Thermal Therapy (PTT), where embedded nanoparticles significantly enhance the absorption of the laser light and are designed to address the specific challenges of thermal therapy. During the last decade, the introduction of nanoparticle assisted Plasmonic Photo Thermal Therapy (PPTT) in the field of nanomedicine, has led chemists, material scientists, and biologists to synthesize and analyze metals with structures ranging from spherical, rod-shaped, to cage geometries. The use of metal nanoparticles has been expanded beyond the use of conventional noble metal nanoparticles, SWNTs, and MWNTs, to include other optically excitable and tunable biocompatible materials that have been engineered to allow for accumulation, selective absorption in the Near Infrared Region (NIR), and subsequent heat generation in cancerous tissue. The main goal of PPTT is to deliver with precision the specified dose of energy to the tumor while avoiding any amount to the healthy tissue and nearby at-risk organs. The absorbed photon energy from the nanoparticles would be readily converted to thermal energy, which immediately brings a sharp temperature difference between the tumor tissue and the surrounding healthy tissues. Although experimental investigation would be the primary tool to explore the medical applications of nanoparticles, it is also well appreciated that numerical investigations based on modeling and simulations could be useful in accelerating the whole research process, reducing research costs and unnecessary repetitive efforts. We have numerically investigated phantom based experiments of PPTT under different conditions. We also have worked in a subfield of PPTT called nanoparticle assisted Laser-induced Interstitial Thermo Therapy (LITT) to treat deeply buried percutaneous tumors. The diffusing laser applicator is placed inside tumors, enabling a more accurate and efficient delivery of energy doses to targeted sites. The current status of the numerical simulations for different types of human tissues that have been used to produce the phantom and experimental conditions to test their therapeutic effects on treatment will be presented. A systematic investigation of the therapeutic effects of several treatment conditions including wavelengths of laser exposure, laser power, exposure time, types and concentrations of tailored nanoparticles, and optical/thermal properties of the host biological tissues will be reviewed.


JOE R. FOWLER Co-Founders Fowler Distinguished Lecture Series Donald W. Fowler ‘66 is a member of the Academy of Distinguished Graduates of the Department of Mechanical Engineering. For over twenty-eight years, his company, Fowler Energy Company, has provided a variety of energy cost-reduction services to large users of electricity, natural gas, water, and wastewater. Don is a registered professional engineer as well as a Fellow of the American Society of Mechanical Engineers. He is a Senior Member of the Society of Petroleum Engineers and a Member of the Association of Energy Engineers. He is a Founder of the Central Texas Section of ASME. Don holds several U.S. and foreign patents related to offshore and onshore processing and transportation of compressed natural gas. Don and his wife Joyce have 5 children, 8 grandchildren, and live in Austin.

Joe R. Fowler ‘68 is both a former member and chair of the Department of Mechanical Engineering’s Developmental and Advisory Board, and he chaired the department’s first capital campaign. Joe is President and co-founder of Stress-Engineering Services, Inc., an engineering consulting firm that provides design, analysis, and testing services to a variety of industries. A registered professional engineer, Joe is a Fellow of the American Society of Mechanical Engineers, a member of the Society of Experimental Mechanics, the Society of Petroleum Engineers, and is a past-president of ABET, Inc. (formerly the Accreditation Board of Engineering and Technology). In 2012, he was named an Ernst & Young Entrepreneur of the Year. Currently, he serves on the Board of the Offshore Technology Conference. Joe and his wife Linda have 3 children (all Aggies), 9 grandchildren, and this year will celebrate their 48th anniversary.

Spring 2013 Endowed Fowler Distinguished Lecture Announcement