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Lyophilization Data Loggers

LYOPHILIZATION The lyophilization process is where perishable food or material is frozen and the water found in the material is sublimated – changing from a solid sate to a gas state without ever entering a liquid state. The water vapor is then removed, the





stable, and can be stored easier. Another term for the process is freeze-drying, or cryodesiccation.

DATA LOGGERS To monitor and validate the temperature data during the lyophilization process, the user must have a logger that can record in ultra-low temperatures. For most lyophilization applications, the data logger being used should include a temperature sensor or probe that is long, thin and flexible for easy manipulation and vial insertion.



Lyophilization data loggers can provide statistics for the experts in many fields, such as: ◉

Red cell freezing units

Plasma observation

Priming biological pharmaceuticals


FEATURES Data loggers don’t have to be difficult to use. Aim for a unit that is easy to operate and small enough to not get in the way. Units with alert indicators that signal the status of the data will be helpful. Other features that prove to be helpful are: ⦿

Password security


Recording in real-time


Delayed start times


Customized alarm notification

ACCESSORIES Below are two optional items that will make the logging process easer: â?‘

A wall mount for your lyophilization data logger. Keep the unit within your reach, visible and out of the way at the same time!


A surface temperature probe attachment. These are created to measure the surface temperature of any

tray or flat object and should slide easily onto the end of the loggers probe.

INTERFACE Transferring data from the logger to a computer should be a breeze. USB cables, docking stations





interface make


process a snap. Always remember to go over

the manual with unfamiliar models.




The harsh temperatures that a lyophilization data logger must record in can cause its sensors to eventually become less precise and need recalibration. Data loggers must be calibrated regularly to keep your recording values

accurate. When you first receive your product, look for the calibration certificate to confirm the date of the calibration and make note of the date when the next calibration is recommended. Another important factor is the manufacturer’s warranty, and if made available, the extended warranty. Check this out to know what is covered and what is not, should something happen to

your data logger.

IN SUMMATION When looking for a lyophilization data logger remember to look for the following: ⦿

Ease of use


Size of device


Included features


Optional accessories


Hardware interface


Software to manage data and reporting



Office: (603) 456-2011 Website: In 1992, Norman Carlson started MadgeTech

and his company has been a global provider of data loggers ever since. MadgeTech is located in New England and the company is founded on innovation, consistency, and quality products.

Ultra-Cold Data Recording with Lyophilization Data Loggers | We explore the function, features, interfaces, and accessories associated with lyophi...

Ultra-Cold Data Recording with Lyophilization Data Loggers | We explore the function, features, interfaces, and accessories associated with lyophi...