TYPENONE IMPROVING LIVES. CURING TYPE 1 DIABETES.
AGE 8 “Unlike other kids,
I have to check my blood sugar 8 to 10 times a day; everything I eat is measured and every carbohydrate counted. My kit goes with me everywhere I go … Too much exercise or not eating all my food can be dangerous. I think I’m too young to have to worry about all this stuff.”
“IT CONTROLS YOUR LIFE IN WAYS THAT
SOMEONE WITHOUT IT DOESN’T EVEN SEE...”
- Nicky Hider, New York
JDRF is the leading global organization funding type 1 diabetes (T1D) research. JDRF’s goal is to progressively remove the impact of T1D from people’s lives until we achieve a world without T1D. JDRF collaborates with a wide spectrum of partners and is the only organization with the scientific resources, regulatory influence, and a working plan to better treat, prevent, and eventually cure T1D.
Type 1 diabetes (T1D) is an autoimmune disease in which a person’s pancreas stops producing insulin, a hormone that enables people to get energy from food. It occurs when the body’s immune system attacks and destroys the insulin-producing cells in the pancreas, called beta cells.
While its causes are not yet entirely understood, scientists believe that both genetic factors and environmental triggers are involved. Its onset has nothing to do with diet or lifestyle. There is nothing you can do to prevent T1D, and—at present — nothing you can do to get rid of it.
We need to be constantly factoring and adjusting, making frequent finger sticks to check blood sugars, and giving ourselves multiple daily insulin injections just to stay alive.â€? - Mary Tyler Moore
EFFECTS Type 1 diabetes strikes both children and adults at any age. It comes on suddenly, causes dependence on injected or pumped insulin for life, and carries the constant threat of devastating complications.
Warning signs of T1D may occur suddenly and can include: •
Drowsiness or lethargy
Sudden weight loss
Sudden vision changes
Sugar in the urine
Fruity odor on the breath
Heavy or labored breathing
Stupor or unconsciousness
While insulin injections or infusion allow a person with T1D to stay alive, they do not cure the disease, nor do they necessarily prevent the possibility of the disease’s serious effects, which may include: kidney failure, blindness, nerve damage, heart attack, stroke, and pregnancy complications.
HOW T1D IS
MANAGED Living with T1D is a constant challenge. People with the disease must carefully balance insulin doses (either by injections multiple times a day or continuous infusion through a pump) with eating and other activities throughout the day and night. They must also measure their bloodglucose level by pricking their fingers for blood six or more times a day. Despite this constant attention, people with T1D still run the risk of dangerous high or low blood-glucose levels, both of which can be life threatening. People with T1D overcome these challenges on a daily basis.
RATE TD1AMONG CHILDREN UNDERAGE OF
MORETHAN 15,000CHILDREN &15,000ADULTS
MANY AS3MILLION AMERICANS HAVET1D
14INCREASE ISESTIMATED TO BY
HEALTHCARE COSTS T1D U.S.EACHYEAR THE
AGE 20 INCREASED
JDRF’s near- to mid-term goals include delivering: •
An automated low-glucose suspend artificial pancreas system, which predicts and prevents severe blood-glucose lows. A treat-to-range artificial pancreas system, which automatically keeps blood-glucose levels in a specified range. The use of existing type 2 diabetes drugs to improve bloodglucose control in people with T1D compared to the use of insulin alone. The use of donated human islets as a treatment for low–blood glucose unawareness.
JDRF’s long-term goals include delivering: •
A beta cell encapsulation product providing insulin independence for more than a year without the need for chronic immunosuppression. Novel therapies for beta cell survival and immune modulation that when used in combination can extend the period of insulin independence after diagnosis for more than two years.
Advanced-generation artificial pancreas systems such as those that deliver two hormones and those that have full (24-hour) automation features that further improve glycemic control. A glucose responsive insulin that provides glycemic control with a single shot per day, or less often. Novel therapies that improve eye disease in people with T1D. Therapies that prevent or delay the onset of insulin dependence for at least two years in people with autoantibodies for T1D.
2012 JDRF RESEARCH
FUNDING CURE RESEARCH
Beta Cell Health and Regeneration Therapies
Beta Cell Encapsulation Therapies
Cure Biomarkers and Imaging Tools
Cure Transportfolio Projects
Artificial Pancreas Systems
Complications Prevention and Treatment Therapies
PREVENTION THERAPIES RESEARCH
General Research Projects
TOTAL 2012 RESEARCH FUNDING
DONATE. GENERAL DONATION MEMORIAL DONATION TRIBUTE DONATION SUPPORT JDRF AT WORK MAKE A STOCK GIFT DONATE YOUR CAR INCLUDE JDRF IN YOUR WILL Your tax-deductible gift will help JDRF create a world without T1D.
FOR MORE INFORMATION VISIT
GET INVOLVED IN YOUR LOCAL CHAPTER WALK TO CURE RIDE TO CURE KIDS WALK TEAM JDRF Working together, JDRF chapter volunteers and staff have been responsible for raising more than $1.7 billion for diabetes research, as well as building supportive communities
TELL YOUR STORY. WHO IS YOUR #1? Visit: http://jdrfstory.org
MAKE A CALL
Making a personal phone call to your Congressional Representative, and Senators.
Every two years in Washington, D.C., JDRF’s Children’s Congress gives children the opportunity to personally show their Congressional Members how they feel about living with T1D and their daily struggles.
SEND A LETTER
Send a letter to your Congressional Representative, and Senators.
Text “ACTION” to “37420” and sign up for our alerts today. (Message and data rates may apply.
TYPE 1 TALK
An online events tool on Facebook that’s specifically designed to help bring the local diabetes community together online.
PROMISE TO REMEMBER ME CAMPAIGN
Meet with your Congressional Members right in their local home office, and make sure that they remember YOU when they question if the federal government should continue to support uninterrupted T1D research.
IMPROVING LIVES. CURING TYPE 1 DIABETES.
GO ONLINE AND VISIT http://jdrf.org PHONE: (800) 533-CURE (2873)