Economic sustainability and digital disruption are pretty popular topics as of late. Health care spending is on an unsustainable path, thanks to demographic shifts and globalization. But just as health systems need to contain costs, digital health has emerged to enable approaches that are significantly more cost-effective. Developing sustainable approaches will require varied skills, from app development and analytics to customer engagement – attracting entrants from sectors such as technology, telecommunications, and retail. This creates opportunities for cross-sector partnering, but also raises the specter of disruption for mature health care incumbents. Here are some of the healthcare trends that will rule not only this year, but many more years to come!