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atlas

catalogue 2009/10

Atlas simply does it all

1


What is Atlas?

atlas automated synthesis system

The Best Value Process Chemistry Reactor Ever! Atlas is a high performance, low cost synthesis system that is flexible and truly easy to use. The intelligent base can be configured to control one or many reactions up to 5 litres in vials, flasks or jacketed reactors.

Easy stirrer seal Chemically resistant, auto aligning stirrer seal and guide

PC control Atlas and third party hardware can be controlled using the Atlas software Quick stirrer set up The stirrer post clicks into the base in seconds Powerful stirring Compact, auto aligning stirrer up to 800RPM

Wide range of sensors Thermocouples, pH sensors, turbidity probes etc. with localised calibration

Quick clamp No tools required to change jacketed vessels in seconds Wide range of stirrers Different styles and lengths available

Quick connections Thermo fluid connections made in seconds

Oil drain unit Press button to drain thermo fluid

Jacketed vessels 100ml, 250ml, 500ml, 1 litre, 2 litre and custom profiles. 5 litre with Remote Mount

Quick clamp Vessel necks are clamped and aligned with one turn

Round bottom flasks 50ml, 100ml, 250ml, 500ml and 1 litre Hotplate/coldplate Hotplate (RT to 280°C) or coldplate (-40 to 160°C)

USB download Download data to USB stick

Parallel chemistry 1 Dry baths are available for 3 round bottom flasks, 6 vials, 12 vials or custom arrangements

Multiple sensors Multiple sensors can be used with the triple socket Magnetic stirring Up to 1200RPM

Parallel chemistry 2 Many bases can be connected together in master/slave mode

Atlas simply does it all

Simple control Twist & click knob to change temperature /stirrer speed or edit and run automated experiments

Atlas benefits

Easy to use: Twist & click knob, large display and intuitive. Automated reactions without PC control: Set points, ramps or sophisticated profiles are all possible for reaction temperature and stirrer speed. Automatic data capture: Data such as temperatures and stirrer speed are logged in a .csv file and can be downloaded to a USB stick. Easy to upgrade to perform: Calorimetry, pH control, gravimetric or volumetric reagent addition, crystallisations, parallel reactions, etc. High performance stirring: 1200RPM magnetic or 800RPM powerful overhead stirrer. Quick: Everything clicks together quickly and easily without tools. Change vessels in under a minute. Small footprint: 23cm (9”) square easily fits in fume cupboards.


contents What is Atlas?

2

Systems

5

Atlas Lithium

6

Atlas Sodium

7

Orbit Systems

8

Atlas Potassium

9

Atlas Volumetric Dosing

10

Atlas Gravimetric Dosing

10

Atlas Turbidity

10

Atlas pH Monitoring and Control

11

Atlas Remote Mount

11

Atlas Reaction Monitoring

12

Atlas SonoLab

12

Atlas FT-IR Spectrometer

12

Atlas Calorimeter

13

Software and Ports

14

Atlas Parallel Systems

15

Reactor Master Basic System

16

Reactor Master Pro System

16

Modules

17

Circulators

24

Software

28

3

3


Orbit and Dry Baths

32

Dry Baths

33

Dry Bath Consumables

35

Orbit Systems and Parts

36

Orbit Consumables

38

Accessories and Consumables

40

Glassware

41

Stirrers

45

Probes

46

Accessories

47

Consumables

49

Atlas Accessories Compatibility Chart

52

What are Custom Reactor Systems?

54

Flow Chemistry

55

4 4


systems Atlas can be configured into a wide range of different systems. To make choosing a system easier, there are three standard Atlas systems named Lithium and Sodium for round bottom flasks (magnetically and overhead stirred respectively) and Potassium for jacketed vessels. Other Atlas systems, designed for specific applications, are also available.

5


Systems

Atlas Lithium

Atlas Lithium automates reactions in round bottom flasks or vials. The Atlas Hotplate (max 280째C) and Stacking Dry Bath can heat round bottom flasks from 50ml to 1 litre giving excellent thermal transfer to the reaction yet the exterior surface remains safe to touch. The Clamp holds a range of different vessel sizes securely and automatically aligns flasks to the Dry Bath. Turning the control knob changes the Hotplate temperature and the Magnetic Stirrer speed (up to 1200RPM). Atlas Lithium also allows users to edit and run profiles automatically from the Base Unit to control heating, cooling, stirring and reagent addition.

Options The Stacking Dry Bath can be substituted for any of the other Dry Baths or Orbit Systems (see Dry Bath section, page 33) and the Atlas Hotplate for a Hot and Cold Plate (2200047). The Hot and Cold Plate module is an easy and accurate way of heating and cooling reactions in flasks and vials. Connected to the Base Unit via a bayonet fitting and to a circulator, the Hot and Cold Plate can be heated up to +160째C and down to -40째C. The circulator is controlled by the Base Unit. The Atlas Lithium can also include the Atlas Syringe Pump (2200072) for volumetric dosing. Controlled by the intuitive Base Unit, the versatile Atlas Syringe Pump can be configured into two refilling flows, or one continuous flow. A choice of dosing modes allows simple additions or intelligent active control parameters including pH and temperature.

A standard Atlas Lithium System contains: Optional Atlas Syringe Pump and Hot and Cold Plate

Description

Part Number

Base Unit

2101000

Hotplate

2101001

Magnetic Stirrer

2101002

Stacking Dry Bath

2101041

Clamp

2101040

Support Rods (Pack of 2)

2101009

Temperature Node

2101021

RTD Probe - PTFE Coated 300mm x 8mm

2101583

6


Systems

Atlas Sodium

Atlas Sodium automates reactions in round bottom flasks. It is equipped with a Magnetic Stirrer (up to 1200RPM) and a Scorpion Overhead Stirrer (up to 800RPM) for viscous reactions or reactions containing large quantities of solids. The Stacking Dry Bath enables heating or cooling of round bottom flasks from 50ml to 1 litre (to 280째C). Accurate reaction temperature control is provided using an in-reaction Temperature Node and RTD Probe. The Clamp holds a range of different vessel sizes securely and automatically aligns flasks to the Dry Bath. Turning the control knob changes the Hotplate temperature and the Magnetic or Scorpion Overhead Stirrer speed. Atlas Sodium also allows users to edit and run profiles automatically from the Base Unit to control heating, cooling, stirring and reagent addition.

Options The Stacking Dry Bath can be substituted for any of the other Dry Baths, or Orbit Systems (see Dry Bath section, page 33) and the Atlas Hotplate for a Hot and Cold Plate (2200047). The Hot and Cold Plate module is an easy and accurate way of heating and cooling reactions in flasks and vials. Connected to the Base Unit via a bayonet fitting and to a circulator, the Hot and Cold Plate can be heated up to +160째C and down to -40째C. The circulator is controlled by the Base Unit. The Atlas Sodium can also include the Atlas Syringe Pump (2200072) for volumetric dosing. Controlled by the intuitive Base Unit, the versatile Atlas Syringe Pump can be configured into two refilling flows, or one continuous flow. A choice of dosing modes allows simple additions or intelligent active control parameters including pH and temperature.

A standard Atlas Sodium System contains: Description

Part Number

Base Unit

2101000

Hotplate

2101001

Magnetic Stirrer

2101002

Scorpion Overhead Stirrer

2101004

Scorpion Overhead Stirrer Support (Sodium)

2101690

Optional Atlas Syringe Pump and Hot and Cold Plate

Temperature Node

2101021

Stirrer Seal and Guide

2101011

Clamp

2101040

Stacking Dry Bath

2101041

8mm Dia RTD Probe Holder

2101547

Support Rods (Pack of 2)

2101009

Stirrer - PTFE 2 Blade Centrifugal 300mm

1802059

RTD Probe - PTFE Coated 300mm x 8mm

2101583

7


Systems

Orbit Systems The Orbit Parallel Reaction Stations are high performance, low cost parallel synthesis systems for research and development chemistry.

They fit

conveniently on an Atlas Hotplate (up to 280째C), Hot and Cold Plate (-40째C to +160째C) or regular hotplate/stirrers (135mm diameter). 6 (24mm diameter, 46ml) or 12 (13mm diameter, 10ml) reaction tubes can be magnetically stirred in an inert atmosphere and be heated with reflux or cooled. It is possible to add reagents under an inert atmosphere via the septa. The Orbit 6 (2200033) or Orbit 12 (2200032) modules lift in and out of the Orbit Reflux Unit (2200031), allowing the tubes to be freely transported as one whilst the water and gas tubes remain connected to the Orbit Reflux Unit. The Orbit 6 and Orbit 12 modules have twist and click lids which supply an inert atmosphere to all the tubes when in place. When the lid is removed, the tubes are automatically re-sealed and are free to be transported individually. The Orbit Reflux Unit requires an inert gas supply (if inert conditions are required) and running cold water or recirculated coolant. Note that the gas connection between the Orbit Reflux Unit and Orbit 6 or Orbit 12 is automatically made and broken as the module is taken in and out. Syrris recommends the Orbit Reflux Circulator (Julabo F200) (see page 38) if running water is not available or not tolerated. An Orbit 6 System contains: Description

Part Number

Orbit 6 (24mm dia, 46ml tubes)

2200033

Orbit Reflux Unit

2200031

Orbit 6 Reaction Tubes (Pack of 6)

2200036

Orbit 6 Tube Caps (Pack of 6)

2200037

Orbit 6 Septa (Pack of 6)

2200038

Orbit 6 Stirrer Bars (Pack of 6)

2200040

Orbit Septa Opener (Pack of 6)

2200041

Orbit Gas Septa Ring (Pack of 5)

2200042

Optional Hot and Cold Plate An Orbit 12 System contains: Description

Part Number

Orbit 12 (13mm dia, 10ml tubes)

2200032

Orbit Reflux Unit

2200031

Orbit 12 Reaction Tubes (Pack of 12)

2200034

Orbit 12 Tube Caps with Septa (Pack of 12)

2200035

Orbit 12 Stirrer Bars (Pack of 12)

2200039

(2 packs) Orbit Septa Opener (Pack of 6)

2200041

Orbit Gas Septa Ring (Pack of 5)

2200042

Orbit 6 and Orbit 12 System

The Orbit 6 and 12 System combines the benefits of the Orbit 12 and Orbit 6 Systems and so allows parallel reactions using 6 x 46ml tubes or 12 x 10ml tubes. The Orbit Reflux Unit can be used with both Orbit 6 and Orbit 12 (see page 37 for more details).

8


Systems

Atlas Potassium Atlas Potassium is designed for chemists who perform reactions in jacketed reactors. With an easy to use vessel clamping system and integral oil drain unit, Atlas Potassium vessels can be changed in under a minute.

Integrated

temperature and circulator control from the Base Unit make reactions easier than ever before. Atlas Potassium can be supplied with a range of vessels including 50ml, 100ml, 250ml, 500ml, 1 litre and 2 litre (see Remote Mount System for up to 5 litres, page 11). Turning the control knob changes circulator temperature and overhead stirrer speed. Atlas Potassium also allows users to edit and run profiles from the Base Unit to automatically control heating/cooling from a circulator, stirring speed and reagent addition (see Volumetric Addition System). Adding PC software allows complex recipe control, real time data plotting and control of third party hardware. Options The Atlas Potassium can also include the Atlas Syringe Pump (2200072) for volumetric dosing. Controlled by the intuitive Base Unit, the versatile Atlas Syringe Pump can be configured into two refilling flows, or one continuous flow. A choice of dosing modes allows simple additions or intelligent active control parameters including pH and temperature. The Atlas Potassium forms the basis of most of the Atlas systems (see later in this “Systems� section). A standard Atlas Potassium System contains: Description

Part Number

Base Unit

2101000

Scorpion Overhead Stirrer

2101004

Temperature Node

2101021

Node Extension

2101023

Triple Node Socket

2101024

Optional Software Stirrer Seal and Guide

2101011

Jacketed Vessel Clamp

2101012

Oil Drain Unit

2101013

Jacketed Vessel Jacketed Vessel Lid (UK, EU or US)

(see page 41) 2101030/2101594

8mm Dia RTD Probe Holder

2101547

Oil Pipes from Reactor to Oil Drain Unit (Pack of 2)

2101014

Reaction Vessel Drip Tray

2101039

Support Rods (Pack of 2)

2101009

Stirrer

(see page 45)

RTD Probe

(see page 46)

Base to Circulator Serial Cable (RJ11 to DB9 Male) Reaction Vessel Seal (FFKM)

9

2400214 2101543


Systems

Atlas Volumetric Dosing Based on an Atlas Potassium, the Atlas Volumetric Dosing System includes an Atlas Syringe Pump (2200072). The Atlas Syringe Pump is a versatile volumetric dosing system that consists of two syringes with valves and can be configured into 2 independent dosing pumps or 1 continuous pump. When connected together, via a USB cable, the Base Unit and Atlas Syringe Pump allow automated dosing without a PC. Profiles of temperature, stirring speed and volume of reagent to be added can be run automatically. The Atlas Syringe Pump automatically pauses if the temperature exceeds a defined maximum. An Atlas Volumetric Dosing System contains: Description

Part Number

Atlas Potassium Atlas Syringe Pump

2200072

Atlas Gravimetric Dosing Based on an Atlas Potassium, the Atlas Gravimetric Dosing System allows a defined mass of reagent to be pumped from a balance to the reactor by a controlled peristaltic pump. The mass flow rate can be defined, monitored and adjusted by using the Atlas Software 1. An Atlas Gravimetric Dosing System contains: Description

Part Number

Atlas Potassium Atlas Ports (2)

2101020

Atlas Software 1

2300102

Denver Summit Balance SI-4002 Watson Marlow Peristaltic Pump 323/DU/D

New

2200043 1802045

Atlas Turbidity

The Atlas Turbidity System is designed for crystallization control and analysis. It allows turbidity to be examined and modified by controlling temperature and/or additions to the vessel. Data is displayed using the Base Unit and can be plotted and monitored using the Atlas Software 1. The Software will take actions dependent on the turbidity value. The Atlas Turbidity Probe (2200156) can be used with any Atlas reactor. Volumetric dosing can be performed using the Atlas Syringe Pump (2200072). See also the Sonocrystallization system (page 12). An Atlas Turbidity System contains: Description

Part Number

Atlas Potassium Turbidity Probe - 400mm

2200156

Turbidity Node

2200157

Options Atlas Software 1

2300102

Atlas Syringe Pump

2200072

10


Systems

Atlas pH Monitoring and Control The Atlas pH Monitoring and Control Systems are designed for people who perform pH sensitive reactions. The Atlas pH Monitoring System is based on the Atlas Potassium. It includes a combined pH and Temperature Node (2200071) to allow Atlas to monitor both reaction temperature and pH (note that this is included instead of the standard Temperature Node). This system can be operated from the Base Unit or via the Atlas Software 1. The Atlas pH Control System also includes an Atlas Syringe Pump (2200072) and can therefore be configured to control the pH of a reaction by adding either acid and/or base as necessary to maintain a set pH value. This functionality is possible with or without the Atlas Software 1. An Atlas pH Monitoring System contains: Description

Part Number

Atlas Potassium (minus the Temperature Node) pH and Temperature Node

2200071

pH Probe - 400mm with Swivel Adaptor

2200029

An Atlas pH Control System contains: Description

Part Number

Atlas pH Control Atlas Potassium (minus the Temperature Node) Atlas Syringe Pump

2200072

pH and Temperature Node

2200071

pH Probe - 400mm with Swivel Adaptor

2200029

Atlas Remote Mount Based on an Atlas Potassium System, the Atlas Remote Mount System enables a jacketed reactor to be mounted on to laboratory scaffolding and be remote from the Base Unit (see Remote Mount flyer for further explanation). The Remote Mount is connected to the Base Unit using an umbilical which provides communications to devices such as the Temperature Node (2101021) and Scorpion Overhead Stirrer (2101004). When the Jacketed Vessel Clamp (2101012) is used with the Remote Mount, it is compatible with vessels of up to 5 litres. An Atlas Remote Mount System contains: Description

Part Number

Atlas Potassium Remote Mount for Jacketed Vessel Clamp

11

2101576


Systems

Atlas Reaction Monitoring Based on an Atlas Potassium, the Atlas Reaction Monitoring System includes an additional temperature node and RTD probe to monitor the jacket temperature. The Atlas Reaction Monitoring System can use a combination of reaction temperature and jacket temperature to accurately monitor both exothermic and endothermic reaction processes either using the Atlas Software 1 or through the Base Unit (also see Atlas Calorimeter, page 13). An Atlas Reaction Monitoring System contains: Description

Part Number

Atlas Potassium Temperature Node

2101021

Node Extension

2101023

RTD Probe - Stainless Steel 100mm x 3mm

2101593

New

Atlas SonoLab

The Atlas SonoLab is a high performance, automated ultrasound system for sonocrystallization and sonomilling. The proprietary ultrasound technology allows reproducible control of crystallizations, enabling selectivity of parameters such as particle size, shape, crystallinity and polymorphism. The Atlas SonoLab System is based on Syrris’ Atlas Potassium System for jacketed vessels with the addition of the Prosonix proprietary ultrasonic flow cell generator and pump. The powerful Atlas Software 1 allows full control of all the important parameters required for sonocrystallization and sonomilling applications. An Atlas SonoLab System contains: Description

Part Number

Atlas Potassium Prosonix SonoLab SL10 Sonocrystallizer Sonocrystallizer Accessories Pack

RD2200250 RD2200251

New Atlas FT-IR Spectrometer Based on an Atlas Potassium, the Atlas FT-IR Spectrometer System includes a Bruker Matrix-MF for online, real time IR analysis. IR data can be plotted by the Atlas Software 1 as with other sensors. A diamond tipped, gold coated probe and industry leading optics allow for the widest possible wave number range, accuracy and speed of analysis. An Atlas FT-IR Spectrometer System contains: Description

Part Number

Atlas Potassium Bruker FTIR Spectrophotometer Matrix-MF

RD2200249

Bruker Atlas Software Drivers

RD2600005

12


Systems

New Atlas Calorimeter The Atlas Calorimeter is a high performance system that can generate power and enthalpy graphs quickly and easily. This, combined with the simple configuration of reaction temperatures, dosing quantities and alarms provides chemistry laboratories with an easy, safe and accurate calorimetry system. The Atlas Calorimeter can be used for Heat Flow Calorimetry (HFC) or Power Compensation Calorimetry (PCC). Based on the standard Atlas Potassium, the Atlas Calorimeter also includes a power supply and the intelligent Atlas Software that can create graphs within seconds. The Atlas Software offers truly easy calorimetry operation. Configuration of parameters such as reaction temperature, dosing quantities, expected power level (e.g. moderate endotherm; strong exotherm) and alarms (with subsequent actions) are defined in an easy to use wizard. Reaction temperatures, reagent addition and pre/post run calibration, are all controlled automatically, eliminating the need for user intervention. Furthermore, the software automatically controls the operation of all experimental parameters, providing highly accurate and efficient performance with user friendly operation. Analysis is made easy by the ‘single click’ plotting of power and enthalpy in real time. Options The Atlas Calorimeter can include many options including the Atlas Syringe Pump (2200072) for volumetric dosing, or a balance (2200043) and peristaltic pump (1802045) for gravimetric dosing. General Calorimetry Specification for HFC and PCC Vessel options: 250ml, 500ml, 1 litre and 2 litre vacuum jacketed reactors. Temperature range: -40°C to 150°C recommended for calorimetry (up to 200°C possible). Reaction power: 100W/litre maximum (50W for PCC). Sensitivity and accuracy: Typically better than 0.1W per kg and 1 to 5% respectively (dependent on settling time and external conditions). Options include: Gravimetric dosing, pH, IR monitoring, turbidity, etc. An Atlas Calorimeter System contains: Description

Part Number

Atlas Potassium (minus regular RTD Probe) Atlas Software 1

2300102

Atlas Calorimetry Software Upgrade

2600003

Atlas Reporting Software

2600002

TTI Power Supply for Calorimetry (230V) / (115V) Heater Rod Temperature Node Quick Response RTD Probe RTD - Stainless Steel 100mm x 3mm for Dry Baths Vacuum Jacketed Vessel Velcro Oil Connector Insulator (Pack of 2)

2200141 / 2200151 (see page 47) 2101021 (see page 46) 2101593 (see page 42) 2200008

Option Atlas Syringe Pump

13

2200072


Systems

Software and Ports Atlas Software 1 is an easy to use PC based application for control and analysis of experiments. Whole systems including stirrers, circulators, RTDs, pumps, balances etc. can be configured using virtually any manufacturer’s apparatus. The “drag and drop” interface means recipes can be created, changed and saved quickly and easily. The Atlas Software 1 (2300102) can not only control the Atlas hardware but also devices from other manufacturers. Most RS232 devices can be connected to the software via a Port (2101020) which plugs in to the computer’s USB connection. The Atlas Software 1 assigns each Port a number which is shown on the Port’s LCD display to make multiple connections easy (see Atlas Software 1, page 29). Running reactions from the Atlas Software 1 allows responses to be continuously monitored and graphed with easy to use alarms and emergency control. Experiments can be modified “on-the-fly” and all reaction data is continuously logged to .csv data files making analysis easy.

An Atlas Software and Ports System contains: Description

Part Number

Atlas Software 1

2300102

Atlas Reporting Software

2600002

Atlas Port(s)

2101020

The Software can interface with analogue devices by also using a convertor. The Software can be configured by the user to control devices (or by Syrris for a fee, see page 30). A sub-section of the current list of pre-configured devices is below:

Balances Denver Pinnacle Mettler PG 5001 and PM Series Oxford Top Pan Sartorius Circulators

Flow meters Aalborg GFM series (mass flow)* Sierra 820 series (mass flow)* pH meters Atlas pH and Temperature Node

Huber Ministat, Nuevo, Unistat, etc

Denver 215E and 215

Haake

Knick Portamess 913

Julabo F series Lauda Proline series

Mettler Toledo MPH 125 pH Turbidity Atlas Turbidity Probe

Pumps Atlas Syringe Pump ProMinent gamma/l (diaphragm)* Cole Palmer Masterflex (peristaltic) IKA (peristaltic) Watson Marlow 323Du (peristaltic) Watson Marlow 520Du (peristaltic) Overhead stirrers

Mettler Toledo Trb8300* Vacuum controller Vacuubrand CVC2000 Temperature sensors Cole Palmer Digisense Sonocrystallization Prosonix SonoLab SL10

IKA Eurostar *With RS232 to analogue converter

FTIR Bruker Matrix MF

14


Systems

New

Atlas Parallel Systems

It is possible to have full parallel control of any of the systems already described in this section by using Atlas Parallel Software 1 (see page 30). The Atlas Parallel Software 1 allows many systems (up to 4) to be connected to one PC and controlled in parallel e.g. up to four of the following systems: Atlas Lithium

Atlas Sodium

Atlas Potassium

Atlas Volumetric Dosing

Atlas Gravimetric Dosing

Atlas Turbidity

Atlas pH Monitoring and Control

Atlas Remote Mount

Atlas Reaction Monitoring

Atlas SonoLab

Atlas FT-IR Spectrometer

Atlas Calorimeter

Atlas Parallel Software 1 opens multiple instances of Atlas Software 1 (2300102) and defines the system to which each piece of apparatus is assigned (such as Atlas Base Units or other manufacturer’s apparatus connected by an Atlas Port). Data from all systems can be viewed in the Run View of any instance of Atlas Software 1 and all can be saved to one common .csv file. The software provides whole system control, configuration and analysis. It not only controls the Atlas hardware, but nearly all RS232 controlled apparatus and analogue sensors can be connected to the software via a simple Port (2101020) which plugs into the computer’s USB connection. This allows automation of any compatible laboratory apparatus with full recipe control. Running reactions from the software allows all responses such as temperature, stirrer speed, pH and mass flow to be continuously monitored and graphically displayed in real time. Apparatus is configured using a simple “drag and drop” interface and recipes can be created, changed and saved with a click of a mouse. Responses from sensors can be continuously monitored and graphed with easy to use alarms and emergency control. Experiments can be modified “on-the-fly” and all reaction data is continuously logged to .csv data files making analysis easy.

15


Systems

New

Reactor Master Basic System

The Reactor Master Basic System automates jacketed reactor systems from other manufacturers and logs data without the need for PC software. Circulators, (e.g. Julabo, Huber, Haake, Lauda etc.) stirrers, (e.g. Heidolph, IKA, Chemglass etc.), thermocouples and RTDs from virtually any manufacturer can be controlled by the twist and click knob. Data can be viewed in real time and downloaded to a USB memory stick as a .csv file. By connecting the circulator, overhead stirrer and thermocouple to the Reactor Master Basic, circulator temperature and stirrer speed can be set by the twist and click knob and displayed on the LCD screen. It is also possible to set stirring and profiles to run in a totally automated fashion. A Reactor Master Basic System contains: Description

Part Number

Reactor Master Basic

RD2200247

Circulator Cable

(see page 48)

Stirrer Cable

(see page 48)

New

Reactor Master Pro System

A Reactor Master Pro System retains all the benefits of the a Reactor Master Basic System but also has the following additional benefits: Reaction temperature control Ability to use Atlas RTD sensors Ability to use Atlas Turbidity sensors Ability to use Atlas pH sensors Ability to upgrade to PC software (to control other manufacturer’s apparatus) A better reaction temperature is achieved by “closed loop” (PID) control of the reactor temperature sensor and the set point of the circulator (rather than simply “open loop” setting of a circulator bath temperature). Connection of Atlas RTDs, pH and turbidity probes is possible via a node extension. Reactor Master Software is an easy to use PC based application for control and analysis of experiments. The “drag and drop” interface means recipes can be created, changed and saved quickly and easily. The software can not only control circulators and stirrers, but almost any RS232 controlled device can be connected to the software via a Port (2101020) which plugs in to the computer’s USB connection.

Running reactions from the software allows responses to be

continuously monitored and graphed with easy to use alarms and emergency control. Experiments can be modified “on-the-fly” and all reaction data is continuously logged to .csv data files making analysis easy. A Reactor Master Pro System contains: Description An Atlas Reaction Monitoring System contains: Reactor Master Pro

Part Number RD2200248

Circulator Cable

(see page 48)

Stirrer Cable

(see page 48)

Reactor Master Software

16

RD2600004


modules Atlas is a low cost modular synthesis system, that is simple to use and quick to set up. Using a fully modular approach, the Base Unit can be configured into a wide range of systems using a selection of modules and accessories.

17


Modules

Base unit

2101000

The Base Unit is the centre of any Atlas system. The Base Unit can be configured into a variety of different systems for different applications such as discovery or process chemistry. In every case, the hardware clicks into place in seconds without the need for tools and can be controlled in three ways: 1) Turn the control knob to change hotplate or circulator fluid temperature and magnetic or overhead stirrer speed. 2) Edit and run profiles automatically from the Base Unit to control heating, cooling, stirring and reagent addition. Without PC control, the intelligent Base Unit can control circulator or reaction temperature, overhead stirrer speed and reagent addition from a pump. Data from sensors such as thermocouples, pH sensors, turbidity probes and stirrers are recorded by the Base Unit and can be downloaded to a USB stick. 3) Use full PC software for complex recipe control, real time data plotting and control of third party hardware. Connect many Base Units for parallel chemistry. The Base Unit has physical and electronic connections for other parts such as the Scorpion Overhead Stirrer (2101004), Magnetic Stirrer (2101002), Hotplate (2101001), Reaction Vessel Drip Tray (2101039), Temperature Node (2101021) (or Triple Node Socket, 2101024) and Support Rods (2101009) for mounting further apparatus. Supply voltage: 100 – 240VAC 50-60Hz Comms ports: 2 x USB A, 1 x USB B, 1 x RS232 RJ11 Construction: Cast aluminium housing, epoxy powder coated (for high chemical resistance) Dimensions: 23cm (9”) square Connection for Scorpion Overhead Stirrer Connection for Nodes (e.g. Temperature, pH, Turbidity) Connection for Atlas Hotplate or Hot and Cold Plate Connection for Magnetic Stirrer

Hotplate (230V)

2101001

New Hotplate (120V)

2101005

The Atlas Hotplate for the Base Unit connects via a bayonet fitting and is automatically detected. The Atlas Hotplate includes a heater and an embedded RTD for feedback of plate temperature and a thermal cut-out for safe operation. The Atlas Hotplate can be controlled directly from the Base Unit front panel to heat either to a set-point or a controlled profile. For use with Dry Baths and Orbit Systems. Maximum temperature: 280°C Cut-out temperature: 400°C Diameter: 135mm

18


Modules

Hot and Cold Plate

2200047

The Hot and Cold Plate connects to the Base Unit via a bayonet fitting and to a circulator (see page 24). The plate temperature (monitored by an embedded RTD) or reaction temperature can be controlled directly from the Base Unit front panel to heat or cool either to a set point or a controlled profile. For use with Dry Baths and Orbit Systems. Minimum temperature: -40째C Maximum temperature: +160째C Diameter: 135mm

2101002

Magnetic Stirrer

The Magnetic Stirrer connects directly to the Base Unit using a bayonet fitting. The stirrer is automatically detected by the Base Unit and stirring can be controlled directly from the front panel with either set-points or profiles. In use, the current stirring rate is shown along with the set-point on the LCD display. Maximum speed: 1200RPM

2101004

Scorpion Overhead Stirrer

The Scorpion Overhead Stirrer provides auto aligning overhead stirring up to 800RPM for Atlas. Connecting directly to the Base Unit, the Scorpion Overhead Stirrer includes a flexible arm and drive head which can be instantly connected to the stirrer guide. The Scorpion Overhead Stirrer requires a Stirrer Seal and Guide (2101011) and can be used with both jacketed vessels and round bottom flasks. Maximum speed: 800RPM Maximum torque: 11 Ncm

2101120

Scorpion Drive Head (without pole)

The Scorpion Drive Head is a replacement part for the Scorpion Overhead Stirrer (2101004). It contains the motor for the Scorpion Overhead Stirrer and it connects to the pole (with flexible arm).

New High Torque Stirrer Adaptor (for Heidolph Stirrers)

2200258

The High Torque Stirrer Adaptor (for Heidolph Stirrers), when used in conjunction with a Heidolph Stirrer (see page 20) offers a high torque (with torque measurement) alternative to the Scorpion Overhead Stirrer (2101004). This adaptor kit includes the following components: Support Rods - These locate into the top of the Jacketed Vessel Clamp Support - This aligns the Heidolph Overhead Stirrer to the Stirrer Seal and Guide (2101011) A quick adaptor between the Heidolph Stirrer and the Stirrer Seal and Guide - This is factory fitted A support post - This replaces the Scorpion Overhead Stirrer post

19


Modules

New

Heidolph RZR 2051 Control Overhead Stirrer (230V / UK)

2200254

New

Heidolph RZR 2052 Control Overhead Stirrer (230V / UK)

2200255

New

Heidolph RZR 2051 Control Overhead Stirrer (230V / EU)

2200267

New

Heidolph RZR 2052 Control Overhead Stirrer (230V / EU)

2200268

New

Heidolph RZR 2051 Control Overhead Stirrer (110V / US)

2200269

New

Heidolph RZR 2052 Control Overhead Stirrer (110V / US)

2200270

The Heidolph RZR Control Overhead Stirrer, when used in conjunction with a Heidolph Stirrer High Torque Stirrer Adaptor (see page 19) offers a high torque (with torque measurement) alternative to the Scorpion Overhead Stirrer (2101004). The Heidolph 2051 has a maximum speed of 2000 RPM and maximum torque of 40 Ncm (peak overload) / 20 Ncm (continuous) with feedback. The Heidolph 2052 has a maximum speed of 1000 RPM and maximum torque of 180 Ncm (peak overload) / 90 Ncm (continuous) with feedback. Control is possible via the front panel of the stirrer or by the Atlas Software 1 (2300102) and Atlas Port (2101020). Note that control is not possible from the Base Unit.

2101011

Stirrer Seal and Guide

The Stirrer Seal and Guide holds a standard 8mm PTFE, or glass stirrer shaft and gives a chemically resistant, vacuum tight seal onto a standard round bottom flask or jacketed vessel lid. An auto-aligning, quick release mechanism allows stirrers to be rapidly changed or adjusted for height as required. The Stirrer Seal and Guide requires a Scorpion Overhead Stirrer (2101004), or High Torque Stirrer (see above).

New Stirrer Seal and Guide Release for Flasks (Sodium)

2200271

When using the Stirrer Seal and Guide (2101011) with round bottom flasks, it is possible to use this device to make the separation of the flask and the Stirrer Seal and Guide easier. The two parts screw apart to assist in releasing the PTFE Male B24 joint of the Stirrer Seal Guide from the ground glass female B24 joint of the round bottom flask.

20


Modules

Atlas Syringe Pump

2200072

The Atlas Syringe Pump is a versatile volumetric dosing system that consists of two syringes and can be configured into 2 independent dosing pumps or 1 continuous pump. The Atlas Syringe Pump can operate in standalone mode by use of the intuitive twist and click knob and large display or can be controlled by the Base Unit, or can be operated by the PC software. There are 5 main modes of operation (standalone modes shown by *): 1:

Dual Dosing* (dose a volume, pump at a flow rate, dose one reagent to

2:

pH control* (dose an acid and/or base to keep pH within a defined range)

reactors or sophisticated profiles) 3:

Continuous* (2 syringe pumps work together to produce 1 continuous flow, i.e. one is refilling while the other is dispensing)

4:

Atlas Base Control Mode (Atlas Syringe Pump can be controlled from the

5:

PC Control Mode (PC software can control Dual Dosing and pH Control in

Base Unit as part of an automated temperature and stirrer speed profile) the same way as the Atlas Syringe Pump in standalone mode) A choice of dosing modes allows simple additions or intelligent active control of parameters using Atlas pH and temperature sensors. Furthermore, a maximum temperature can be set to pause the Atlas Syringe Pump in the case of an exotherm. Each syringe has a corresponding valve which can access up to 6 ports. Each of the ports on each valve can be configured to be an input or output, therefore, it is possible to pump from up to 5 sources to one reactor, etc. per syringe. 2 syringes (2.5ml are supplied by default). See page 51 for other sizes. 2 valves (4 ports per valve are supplied by default which can be configured as inputs or outputs). See page 50 for other sizes. Flow rates: 0.5ul/min to 20ml/min Chemically resistant: PTFE, PCTFE and glass wetted parts

New Atlas Syringe Pump - without Valves or Syringes

2200100

The Atlas Syringe Pump (2200072) is supplied with 4 ports and 2.5ml syringes by default. The Atlas Syringe Pump without valves or syringes allows valves and syringes to be purchased separately. It is possible to specify 2, 3, 4, or 6 port valves and syringe volumes of 50ul, 100ul, 250ul, 500ul, 1ml, 2.5ml and 5ml. See pages 50-51 for these and more accessories.

New Autosampler Module (for Atlas Syringe Pump)

2200196

The Autosampler Module is designed for use with the Atlas Syringe Pump (2200072) and Autosampler Probe (2200197) to aspirate up to 6 samples from a reactor at user defined intervals. The Autosampler Module, which can be mounted on the extra pair of Support Rods provided, holds 6 x 2ml HPLC vials and is located, in a fluidic sense, between the Atlas Syringe Pump and the Autosampler Probe. The Atlas Syringe pump can sequentially aspirate samples from the reactor into the vials (which can contain a chemical quench if required).

New Autosampler Probe (for Atlas Syringe Pump)

2200197

The Autosampler Probe is designed for use with the Atlas Syringe Pump (2200072) and Autosampler Module (2200196) to aspirate up to 6 samples from a reactor into HPLC vials at user defined intervals. The Autosampler Probe consists of 6 PTFE pipes held in a chemically resistant (PTFE and glass) sheath, which can be located in a Jacketed Reactor Lid port (see page 43). Each of the PTFE pipes is connected to the Autosampler Module.

21


Modules

Temperature Node

2101021

The Temperature Node allows RTD Probes to connect to the Base Unit. The temperature measured by the RTD Probe is displayed on the front panel of the Base Unit. Up to 6 nodes can be connected to a single Base Unit which can each be named to prevent confusion. The Temperature Node can be used with a Node Extension (2101023), Triple Node Socket (2101024) and Six Way Node Socket (2200259) and requires an RTD Probe (see page 46 for options).

pH and Temperature Node

2200071

This module consists of a pH Node and a Temperature Node and can be used to measure either pH or temperature, or both. When used together, the pH is automatically temperature compensated. The functionality of the Temperature Node is exactly the same as the independent Temperature Node (2101021). The pH Node can measure pH values from 0-14, has a 2 point user calibration and can read to better than 0.1 pH accuracy, dependant upon calibration. The pH reading can be viewed on the Base Unit (2101000) and also the full pH value history can be downloaded to a USB memory stick in .csv format. The pH and Temperature Node can be clipped onto the Support Rods (2101009) and plugs into the Triple Node Socket (2101024). The pH Probes (see page 46) plug into the pH Node and RTDs plug into the Temperature Node (see page 46).

New Turbidity Node

2200157

The Turbidity Node allows the Turbidity Probe (2200156) to connect to the Base Unit (2101000). The turbidity measured is displayed on the front panel of the Base Unit. Up to 6 nodes can be connected to a single Base Unit which can each be named to prevent confusion. The Turbidity Node can be used with a Node Extension (2101023) and Triple Node Socket (2101024) or Six Way Node Socket (2200259) and requires a Turbidity Probe (2200156).

Node Extension

2101023

The Node Extension allows nodes to be connected away from the main Base Unit (2101000). The Node Extension includes a clip to connect it to the Support Rods (2101009). The Node Extension must be connected to a Triple Node Socket (2101024), a Six Way Node Socket (2200259) or the Atlas Syringe Pump (2200072) and works with all nodes.

Triple Node Socket

2101024

The Triple Node Socket connects to the node port at the rear right of the Base Unit (2101000) and can be used to connect up to three Nodes (e.g. temperature, pH and temperature, or turbidity) to the base via Node Extensions (2101023).

New Six Way Node Socket

2200259

The Six Way Node Socket connects to the node port at the rear right of the Base Unit (2101000) and can be used to connect up to six Nodes (e.g. temperature, pH and temperature, or turbidity) to the base via Node Extensions (2101023).

22


Modules

Jacketed Vessel Clamp

2101012

The Jacketed Vessel Clamp is a quick-release clamping mechanism for Atlas jacketed reactors. Designed to make changing reactors both quick and easy, the vessel clamp has a simple control to clamp and release the reactor and lid simultaneously. The reactor clamp fits onto the Support Rods (2101009) and features supports for a Node Extension (2101023) and a further pair of Support Rods.

Remote Mount for Jacketed Vessel Clamp

2101576

The Remote Mount allows a vessel assembly (including Jacketed Vessel, Jacketed Vessel Clamp and Oil Drain Unit) to be located away from the Base Unit (2101000).

The Remote Mount can attach to standard laboratory

scaffolding and is connected to the Atlas system using an umbilical which provides communications to devices such as the Temperature Node (2101021) and the Scorpion Overhead Stirrer (2101004). When the Jacketed Vessel Clamp is used with the Remote Mount, it is compatible with vessels of up to 5 litres.

Clamp

2101040

The Atlas Clamp is a quick-release clamping mechanism for reaction flasks and other devices. Flasks can be pushed into the spring loaded jaws where they can be locked with a simple twist action. The Clamp is mounted on Support Rods (2101009) on the rear of the Base Unit (2101000) and can be quickly released or its height changed. The round bottomed flask always remains aligned to the centre of the Base Unit and Stacking Dry Bath (2101041), if used.

Scorpion Overhead Stirrer Support (Sodium)

2101690

When overhead stirring round bottomed flasks, this module should be used to support the Stirrer Seal and Guide (2101011) for use with the Scorpion Overhead Stirrer (2101004) and round bottom flasks (see page 43) . It connects to the Support Rods (2101009) and rests on top of the Clamp (2101040) to allow the flask, stirrer and Stirrer Seal and Guide (2101011) to be safely removed as one from the Stacking Dry Bath (2101041).

Triple Clamp

2101043

The Triple Clamp is a three position clamping mechanism designed to be used with the Triple Dry Bath (2101042) and can hold up to three flasks which can be different sizes. The Triple Clamp has a mechanism which holds a range of different neck sizes in spring loaded jaws which can be locked into position. The Triple Clamp is locked into position on the Support Rods (2101009) which holds it aligned with the three positions of the Triple Dry Bath.

Oil Drain Unit

2101013

The Oil Drain Unit provides the ability to drain oil from a Jacketed Reactor Vessel back into a recirculator without exposure to the oil. It is connected to a recirculator using Oil Pipes (2101015) with two M16 fittings and to a reaction vessel with Oil Pipes (2101014) using quick release fittings. The Oil Drain Unit fits over the Support Rods (2101009).

23


Modules

Port

2101020

Atlas Ports are an interface between RS232 devices and the Atlas Software 1 (2300102). Up to 6 Atlas Ports can be connected to a PC via USB. Ports feature an LCD display which displays the number of the port to make connections easy. RS232 devices such as pumps, balances, sensors, etc. can be added to the Atlas system. Each RS232 device connected to the PC requires a separate Port (see the Software and Ports System, page 14).

Circulators

Julabo Circulators Syrris can offer a wide range of Julabo circulators for heating and/or cooling, jacketed reactors or the Hot and Cold Plate (2200047). All these systems can be fully integrated with Atlas giving direct control from the Base Unit (2101000) or through the Atlas Software 1 (2300102) making Julabo systems suitable for a wide range of applications.

New Platinum Stacking Dry Circulator Bath (Julabo LH85) 230V / 50Hz

2200215 2101041

New Platinum Triple DryCirculator Bath (Julabo LH85) 230V / 60Hz

2200216 2101042

Heating capacity: 1800W Cooling capacity: 200 1500

20

-20

-40

-60

-80

°C

1000

900

700

500

100

W

Flow rate: 33 l/min Temperature range: -80 to +250°C Dimensions (W x L x H): 50 x 59 x 64cm

New Gold TripleHot DryCirculator Bath (Julabo LH40) 230V / 50Hz

2200217 2101042

New Gold Orbit Hot 6 System Circulator (Julabo LH40) 230V / 60Hz

2200076 2200218

Heating capacity: 2600W Cooling capacity: 200 1500

20

-20

-40

°C

1000

400

50

W

Flow rate: 33 l/min Temperature range: -40 to +250°C Dimensions (W x L x H): 30 x 49 x 64cm

Orbit Cold Gold 12 System Circulator (Julabo FP51-SL) 230V / 60Hz / 3Phase

2200003 2200075

Orbit Cold Gold 12 System Circulator (Julabo FP51-SL) 400V / 50Hz / 3Phase

2200075 2200013

Heating capacity: 3000W Cooling capacity: 20 2000

0

-20

-40

°C

1500

1000

260

W

Flow rate: 22-26 l/min Temperature range: -51 to +200°C Dimensions (W x L x H): 46 x 55 x 89cm

24


Modules

Orbit 12 Silver Circulator System (Julabo FP50-MC) 230V / 50Hz

2200075 2200012

Orbit 12 System (Julabo FP50-MC) 230V / 60Hz Silver Circulator

2200075 2200002

Heating capacity: 2000W Cooling capacity: 20 900

0

-20

-40

°C

800

500

160

W

Flow rate: 11-16 l/min Temperature range: -50 to +200°C Dimensions (W x L x H): 42 x 49 x 70cm

New Bronze Orbit 12Circulator System (Julabo CF41) 230V / 50Hz

2200075 2200223

New Bronze Orbit 12Circulator System (Julabo CF41) 115V / 60Hz

2200222 2200075

Heating capacity: 2000W Cooling capacity: 20 470

0

-20

-30

°C

400

280

120

W

Flow rate: 22-26 l/min Temperature range: -40 to +200°C Dimensions (W x L x H): 28 x 46 x 46cm

Orbit 12 System Circulator (Julabo CF40) 115V / 60Hz

2200075 2200001

Circulator (Julabo CF40) 230V / 50Hz Orbit 12 System

2200011 2200075

New Circulator (Julabo CF40) 100V / 60Hz Orbit 12 System

2200191 2200075

Heating capacity: 2000W Cooling capacity: 20 470

0

-20

-30

°C

400

280

120

W

Flow rate: 15 l/min Temperature range: -40 to +150°C Dimensions (W x L x H): 28 x 46 x 46cm

New Copper Orbit 12 Circulator System (Julabo CF30) 230V / 50Hz

2200226 2200075

New Copper Orbit 12 Circulator System (Julabo CF30) 115V / 60Hz

2200075 2200225

New Copper Orbit 12 Circulator System (Julabo CF30) 100V / 60Hz

2200224 2200075

Heating capacity: 2000W Cooling capacity: 20 320

0

-20

°C

250

150

W

Flow rate: 15 l/min Temperature range: -30 to +150°C Dimensions (W x L x H): 24 x 46 x 40cm

25


Modules

Orbit Circulator 12 System (Julabo F200) 240V / 50Hz

2200059 2200075

New Orbit Circulator 12 System (Julabo F200) 115V / 60Hz

2200075 2200183

New Orbit Circulator 12 System (Julabo F200) 100V / 60Hz

2200075 2200220

The Julabo F200 offers an environmentally friendly way of providing cooled water for reflux systems (such as Orbit). The F200 is a low power cooling recirculator (it does not offer any heating capacity) providing up to 200W of cooling over a temperature range of 5 to 40째C. The small footprint makes this ideal for bench-top operation whilst the maximum flow rate of 8 litres per minute provides excellent cooling for a range of chemistry applications.

Watson Marlow Peristaltic Pump 323/DU/D

1802045

The Watson Marlow Peristaltic Pump 323/DU/D can be connected to an Atlas system to provide pumping of a wide range of liquids into any type of vessel. The pump can provide pumping rates from 1ml/min up to 2 litres per minute depending on the tubing used. An extension module (1802046) can be used to pump multiple liquids simultaneously (see page 50 for tubing).

Denver Summit Balance SI-4002

2200043

The Denver Summit Balance can be connected to the PC via a Port (2101020) for control using the Atlas Software 1 (2300102). It can be combined with the Watson Marlow Peristaltic Pump 323/DU/D (see above) to enable gravimetric dosing of a reagent. Weighing capacity: 4000g Readability: 0.01g

New TTI Power Supply for Calorimetry (230V)

2200141

New TTI Power Supply for Calorimetry (115V)

2200151

The TTI Power Supply is a key part of the Atlas Calorimeter, enabling Heat Flow Calorimetry (HFC) and Power Compensation Calorimetry (PCC). The TTI Power Supply is used with the Heater Rod (see page 47). The Power Supply, controlled entirely by the Atlas Software 1 (2300102) delivers a known power for calibrating HFC experiments or controls the temperature of the reaction during PCC experiments.

26


Modules

New Prosonix Sonolab SL10 Sonocrystallizer New Sonocrystallizer Accessories Pack

RD2200250

RD2200251

The Prosonix Sonolab System is a high performance system allowing full control of crystallization processes. Using proprietary, ultrasound technology, the Sonolab allows complete control of particle size, shape, crystallinity and polymorphism in a completely automated and easy to use platform. The Sonolab can be integrated with the Atlas Potassium system for jacketed vessels with the addition of proprietary ultrasound flow cell, generator and pump. The powerful Atlas Software (2300102) allows full control of all the important parameters required for sonocrystallization, sonomilling and sonochemistry applications. New Bruker FTIR Spectrophotometer Matrix-MF

RD2200249

New Bruker Atlas Software Drivers

RD2600005

The Atlas FT-IR Spectrometer System includes a Bruker Matrix-MF for on-line, real time IR analysis. IR data can be plotted by the Atlas Software 1 (2300102) as with other sensors. A diamond tipped, gold ATR coated probe and industry leading optics allow for the widest possible wave number, accuracy and speed of analysis. Source: MID IR Spectal range: 3,500 - 560cm-1 Beam splitter: KBr MCT detector: Liquid N2 cooled (optional closed cycle MCT) Probe: Diamond ATR probe Temperature: -100°C to +180°C Probe head length: 290mm ±20mm Probe head diameter: 6mm

New Reactor Master Basic

RD2200247

New Reactor Master Pro

RD2200248

New Reactor Master Software

RD2600004

The Syrris Reactor Master automates jacketed reactor systems (e.g. CHEMGLASS, DIEHM, IKA, etc.) and logs data without the need for PC software. Circulators, stirrers, thermocouples and RTDs from virtually any manufacturer can be controlled by the twist and click knob. Data can be viewed in real time and downloaded to a USB memory stick as a .csv file. By connecting the circulator, overhead stirrer and thermocouple to the Reactor Master, temperature and stirrer speed can be set by the twist and click knob and displayed on the LCD screen. It is also possible to set stirring and profiles to run in a totally automated fashion. Reactor Master Pro, also allows the following benefits: Reaction temperature is controlled by PID rather than simply setting circulator bath temperature. Connection of Atlas RTDs, pH and turbidity nodes and probes is possible via a node extension. Upgrade to full Reactor Master PC Software control (similar functionality to Atlas Software 1, 2300102).

27


software Modules

Atlas Software is an easy to use PC based application for control and analysis of experiments. Whole systems including stirrers, circulators, RTDs, pumps, balances, etc. can be configured using virtually any manufacturer’s apparatus. The “drag and drop” interface means recipes can be created, changed and saved with a click of a mouse.

28


Software

Atlas Software 1

2300102

Although the Base Unit (2101000) can control reaction profiles and log data, Atlas Software 1 provides whole system control, configuration and analysis. The intuitive PC-based application enables multiple systems such as stirrers, circulators, pumps and balances to be intelligently combined using virtually any manufacturers apparatus (see below). The Atlas Software not only controls the Atlas hardware, but nearly all RS232 controlled apparatus and analogue sensors can be connected to the software via a simple Port (2101020) which plugs into the computer’s USB connection. This allows automation of any compatible laboratory apparatus with full recipe control. Running reactions from the Atlas Software 1 allows all responses such as temperature, stirrer speed, pH and mass flow to be continuously monitored and graphically displayed in real time. Apparatus is configured using a simple “drag and drop” interface and recipes can be created, changed and saved with a click of a mouse. Running reactions from the Atlas Software 1 allows responses to be continuously monitored and graphed with easy to use alarms and emergency control. Experiments can be modified “on-the-fly” and all reaction data is continuously logged to .csv data files making analysis easy. Virtually any RS232-enabled device with ASCII communications can be configured, The current list of pre-configured devices is below: Balances Flow meters Aalborg GFM series (mass flow)* Denver Pinnacle Mettler PG 5001 and PM Series Sierra 820 series (mass flow)* Oxford Top Pan pH meters Sartorius Atlas pH and Temperature Node

Circulators Denver 215E and 215

Huber Ministat, Nuevo, Unistat, etc

Knick Portamess 913

Haake

Mettler Toledo MPH 125 pH Julabo F series

Turbidity Lauda Proline series Atlas Turbidity Probe Pumps Mettler Toledo Trb8300*

Atlas Syringe Pump Vacuum controller

ProMinent gamma/l (diaphragm)* Vacuubrand CVC2000 Cole Palmer Masterflex (peristaltic)

Temperature sensors IKA (peristaltic) Cole Palmer Digisense Watson Marlow 323Du (peristaltic) Sonocrystallization Watson Marlow 520Du (peristaltic) Prosonix SonoLab SL10 Overhead stirrers IKA Eurostar *With RS232 to analogue converter FTIR Bruker Matrix MF

29


Software

New Atlas Profile Editor Software

2600010

Atlas profiles are a series setpoints and ramps of reaction temperature, stirring speed and volume of reagent added (from the Atlas Syringe Pump). These profiles can be created, saved, edited and run using just the Base Unit (without PC control), however, the Atlas Profile Editor Software allows profiles to be created, saved and edited in graphic or tabular form using PC software. They can be transferred from the PC to the Base Unit via a USB stick or USB lead, to be run on the Base Unit. Alternatively the profile can be run directly from the PC. This has the benefit of being able to monitor the progress of the reaction graphically within graphs rather than showing single point values on the Base Unit LCD. All the result data is stored and can be loaded to see historical data. If control of other manufacturer's apparatus is required or sophisticated recipe control is required, use Atlas Software 1 (see page 29).

New Atlas Parallel Software 1 (2 Bases) - Requires 2300102

2600006

New Atlas Parallel Software 1 (3 Bases) - Requires 2300102

2600007

New Atlas Parallel Software 1 (4 Bases) - Requires 2300102

2600008

The Atlas Parallel Software 1 allows many systems (up to 4) to be connected to one PC and controlled in parallel. Atlas Parallel Software 1 opens multiple instances of Atlas Software 1 (2300102) and defines the system to which each piece of apparatus is assigned (such as Atlas Base Units or other manufacturer’s apparatus connected by an Atlas Port). Data from all systems can be viewed in the Run View of any instance of Atlas Software 1 and all can be saved to one common .csv file.

New RS232 Device Supplied for Integration with PC s/w

RD2600010

New RS232 Device not Supplied for Integration with PC s/w

RD2600009

The Atlas Software 1 (2300102) can control apparatus from other manufacturers that have ACSII RS232 communications. Syrris has already configured a wide range of different apparatus types from a large number of manufacturers. It is possible to configure virtually any RS232 controlled apparatus (not already configured) using the software. However, due to the relatively complex nature of this task, it is possible for Syrris to offer a configuration service. If the apparatus is loaned to Syrris to assist with the integration testing, please use part number RD2600010. If the apparatus is not available to be loaned to Syrris for integration testing, please use part number RD2600009.

New Atlas Reporting Software

2600002

The Atlas Reporting Software allows easy graphical analysis of log files generated by either the Base Unit (2101000), Atlas Software 1 (2300102), or Atlas Syringe Pump (2200072). Log files (in .csv format) are imported by this wizard style software for the easiest possible graphing. Graphs are easily customisable and can be exported as an image, PDF or .csv format. When a calorimetry log file, generated by the Atlas Calorimetry Software Upgrade (2600003) is imported, many other features are unlocked (see the Atlas Calorimetry Software Upgrade description, page 31).

30


Software

New Atlas COM Port Software

2600001

Atlas COM Port Software 1 has the same functionality as Atlas Software 1 (2300102) with the exception that it uses RS232 connection directly to the PC rather than via an Atlas Port (2101020). The Atlas COM Port Software 1 is not recommended for the majority of customers. It is only recommended for those familiar with RS232 COM ports.

New Atlas Calorimetry Software Upgrade

2600003

The Atlas Calorimetry Software Upgrade allows the Atlas Software 1 (2300102) to perform automated Heat Flow Calorimetry (HFC) or Power Compensation Calorimetry (PCC). See the Atlas Calorimetry System (page 13) for the associated, required hardware. Calorimetry experiments can be created in seconds by wizard style actions for PCC or HFC. User inputs such as reaction temperature, expected heat flux, volume and flow rate of automated reagent addition allow the experiment to be performed automatically. Alarms and safety shutdown thresholds enable the system to shutdown safely in the case of an unexpected event. When running, approximate power and enthalpy data can be plotted in real time. For full data analysis, the Atlas Calorimetry Software Upgrade also unlocks functionality in the Atlas Reporting Software (2600002) that can generate calibrated power and enthalpy graphs and correct for sensible heat of addition.

31


orbit and dry baths Syrris offer a range of products which fit on an Atlas Hotplate, Hot and Cold Plate and other hotplates, e.g. IKA. These are capable of heating or cooling one or many round bottom flasks, vials or reaction tubes.

32


Orbit and Dry Baths

Dry Baths Stacking Dry Bath

2101041

The Stacking Dry Bath is an advanced way of heating round bottom flasks without the issues associated with oil baths. The Stacking Dry Bath has a series of concentric cups to hold round bottom flasks from 50ml to 1 litre. The cups provide excellent thermal transfer to optimise heating times. The exterior of the Dry Bath is safe to touch even when the Dry Bath is hot. The Stacking Dry Baths can safely operate with plate temperatures up to 280°C and down to -80°C. The Stacking Dry Baths are light in comparison to other Dry Baths, reducing the mass of the block to be heated, improving heat-up and cool down times. The innovative design also means that the Stacking Dry Bath can be used with 50, 100, 250, 500 and 1000ml round bottom flasks. Use the Dry Bath with a Clamp (2101040) for quick alignment of flasks to the correct position. The Stacking Dry Bath is compatible with most third party stirrer hotplates (including IKA).

Triple Dry Bath

2101042

The Triple Dry Bath is a three position version of the Stacking Dry Bath. The three positions each have inserts from 50ml to 250ml (not shown) and each position can hold a different volume. Use the Triple Dry Bath with the Triple Clamp (2101043) to hold up to three flasks in the correct position. The Triple Dry Bath is also compatible with other stirrer hotplates (including IKA).

Large Vial Bath (6 x 28mm dia)

2200080

The Large Vial Bath is a safe, clean and quick way of heating or cooling up to 6 vials or reaction tubes of 28mm diameter. Each well is 30mm deep equating to a directly heated volume of approximately 16ml. The Large Vial Bath is made up of two parts (the Dry Bath Base and Large Vial Bath Insert) which allows the insert to be changed to accept other vial sizes or round bottom flasks. The vial bath contains a thermowell to accept an RTD Probe (2101593) and a has an insulated surround.

Medium Vial Bath (8 x 20mm dia)

2200079

The Medium Vial Bath will heat and cool up to 8 vials or reaction tubes of 20mm diameter. The Medium Vial Bath is designed to fit Wheaton “V” vials (see page 35). The Medium Vial Bath is made up of two parts (the Dry Bath Base and Medium Vial Bath Insert) which allows the insert to be changed to accept other vial sizes or round bottom flasks. The vial bath contains a thermowell to accept an RTD Probe (2101593) and a has an insulated surround.

Small Vial Bath (12 x 17mm dia)

2200078

The Small Vial Bath will heat and cool up to 12 vials or reaction tubes of 17mm diameter. Each well is 30mm deep equating to a directly heated volume of approximately 5.5ml. The Small Vial Bath is made up of two parts (the Dry Bath Base and Small Vial Bath Insert) which allows the insert to be changed to accept other vial sizes or round bottom flasks. The vial bath contains a thermowell to accept an RTD Probe (2101593) and a has an insulated surround.

33


Orbit and Dry Baths

Custom Vial Bath

2200081

The Custom Vial Bath allows the needs of every vial size to be met. Simply state the size of the vial or reaction tube to be heated or cooled and our engineers will create a custom vial bath to fit.

Dry Bath Base

2200060

The Dry Bath Base is used to heat or cool 1 litre round bottom flasks and also accepts all the dry bath inserts for round bottom flasks (2200061 - 2200064) and vials (2101607 - 2101609 and 2200053). The exterior of the Dry Bath is insulated for safety and the unique design creates a natural convection current to enable rapid cooling after switching off the hotplate. The Dry Bath Base fits on the Atlas Hotplate (2101001), Hot and Cold Plate (2200047) and most third party stirrer hotplates (with 135mm diameter). Note that to use a flask insert, all the larger flask inserts must also be present.

Individual Dry Bath Inserts The Dry Bath inserts fit into the Dry Bath Base (2200060) and can accept round bottom flasks or vials. As the round bottom flask inserts are concentric, to use a particular size, all the larger sizes must also be present. The vial bath inserts all fit directly into the Dry Bath Base. All the inserts have a thermowell to accept an RTD Probe (2101593).

Dry Bath Insert 500ml

2200064

Dry Bath Insert 250ml

2200063

Dry Bath Insert 100ml

2200062

Dry Bath Insert 50ml

2200061

Large Vial Bath Insert (6 x 28mm dia)

2101609

Medium Vial Bath Insert (8 x 20mm dia)

2101608

Small Vial Bath Insert (12 x 17mm dia)

2101607

Vial Bath Insert - Custom

34

2200053


Orbit and Dry Baths

Dry Bath Consumables Vials for Vial Baths Syrris has identified a number of vials to work with the different size Vial Baths available. Pack sizes are shown in brackets below. The large and small Vials are each packed with caps and PTFE faced silicone septa. The Medium Vials are Wheaton “V� Vials and are capable of withstanding overpressure. These Vials have a V shaped base for better recovery of material and are not equipped with a septa.

Large Vials (28mm dia, 20ml) With Caps and Septa (100)

2200069

Large Vials (28mm dia, 40ml) With Caps and Septa (100)

2200070

Pressurisable Medium Vials (20mm dia, 2ml) With Caps (12)

2200065

Pressurisable Medium Vials (20mm dia, 3ml) With Caps (12)

2200067

Pressurisable Medium Vials (20mm dia, 5ml) With Caps (12)

2200068

Small Vials (17mm dia, 8ml) With Caps and Septa (200)

2200066

PTFE Magnetic Stirrer Bars Syrris recommend these PTFE coated magnetic stirrer bars for use with Atlas in the above vials.

Cross (10 x 5mm) for large 28mm Vials (Pack of 10)

2200051

Oval (15 x 6mm) for large 28mm Vials (Pack of 10)

2200052

Wheaton V Spin Vane for medium 20mm Vials (Pack of 12)

2200083

Round (15 x 4.5mm) for large 28mm Vials (Pack of 10)

2200050

Round (12 x 3mm) for small 17mm Vials (Pack of 10)

2200049

35


Orbit and Dry Baths

Orbit - Systems and Parts Orbit Systems

The Orbit Parallel Reaction Stations are high performance, low cost parallel synthesis systems for research and development chemistry. They fit conveniently on the Atlas Hotplate (2101001), Hot and Cold Plate (2200047) or regular hotplate (135mm diameter). 6 (24mm diameter, 46ml) or 12 (13mm diameter, 10ml) reaction tubes can be magnetically stirred in an inert atmosphere and be heated to 280°C with reflux or cooled to –40°C. It is possible to add reagents under an inert atmosphere via the septa. The Orbit 6 (2200033) or Orbit 12 (2200032) modules lift in and out of the Orbit Reflux Unit (2200031), allowing the tubes to be freely transported as one whilst the water and gas tubes remain connected to the Orbit Reflux Unit. The Orbit 6 and Orbit 12 modules have twist and click lids which supply an inert atmosphere to all the tubes when in place. When the lid is removed, the tubes are automatically re-sealed and are free to be transported individually. The Orbit Reflux Unit requires an inert gas supply (if inert conditions are required) and running cold water or re-circulated coolant. Note that the gas connection between the Orbit Reflux Unit and Orbit 6 or Orbit 12 is automatically made and broken as the module is taken in and out. Syrris recommends the Orbit Reflux Circulator (Julabo F200, page 38) if running water is not available or tolerated.

Orbit 6 System

2200076

The Orbit 6 System is a convenient combination of parts, accessories and consumables to allow up to 6 parallel reactions to be stirred and heated/cooled under an inert atmosphere. The Orbit 6 System fits on the Atlas Hotplate (2101001), Hot and Cold Plate (2200047) and most third party stirrer hotplates. The Orbit 6 System contains the following parts and consumables.

Description

Part Number

Orbit 6 (24mm dia, 46ml tubes)

2200033

Orbit Reflux Unit

2200031

Orbit 6 Reaction Tubes (Pack of 6)

2200036

Orbit 6 Tube Caps (Pack of 6)

2200037

Orbit 6 Septa (Pack of 6)

2200038

Orbit 6 Stirrer Bars (Pack of 6)

2200040

Orbit Septa Opener (Pack of 6)

2200041

Orbit Gas Septa Ring (Pack of 5)

2200042

36


Orbit and Dry Baths

Orbit 12 System

2200075

The Orbit 12 System is a convenient combination of parts, accessories and consumables to allow up to 12 parallel reactions to be stirred and heated/cooled under an inert atmosphere. The Orbit 12 System fits on the Atlas Hotplate (2101001), Hot and Cold Plate (2200047) and most third party stirrer hotplates. The Orbit 12 System contains the following parts and consumables.

Description

Part Number

Orbit 12 (13mm dia, 10ml tubes)

2200032

Orbit Reflux Unit

2200031

Orbit 12 Reaction Tubes (Pack of 12)

2200034

Orbit 12 Tube Caps with Septa (Pack of 12)

2200035

Orbit 12 Stirrer Bars (Pack of 12)

2200039

Orbit Septa Opener (Pack of 6)

2200041

Orbit Gas Septa Ring (Pack of 5)

2200042

Orbit 6 and Orbit 12 System

2200077

The Orbit 6 and Orbit 12 System combines the benefits of the Orbit 12 and Orbit 6 Systems (above) and so allows parallel reactions using 6 x 46ml tubes or 12 x 10ml tubes. The Orbit Reflux Unit can be used with both the Orbit 6 and Orbit 12.

Description

Part Number

Orbit 6 (24mm dia, 46ml tubes)

2200033

Orbit 12 (13mm dia, 10ml tubes)

2200032

Orbit Reflux Unit

2200031

Orbit 6 Reaction Tubes (Pack of 6)

2200036

Orbit 6 Tube Caps (Pack of 6)

2200037

Orbit 6 Septa (Pack of 6)

2200038

Orbit 6 Stirrer Bars (Pack of 6)

2200040

Orbit 12 Reaction Tubes (Pack of 12)

2200034

Orbit 12 Tube Caps with Septa (Pack of 12)

2200035

Orbit 12 Stirrer Bars (Pack of 12)

2200039

Orbit Septa Opener (Pack of 6)

2200041

Orbit Gas Septa Ring (Pack of 5)

2200042

37


Orbit and Dry Baths

Orbit 6 (24mm dia, 46ml tubes)

2200033

The Orbit 6 unit holds 6 reaction tubes (46ml, 24mm diameter) allowing the bottom of the tube to be heated while the top is cooled to as a reflux condenser. The Orbit 6 module lifts in and out of the Orbit Reflux Unit (2200031), allowing the tubes to be freely transported as one whilst the water and gas tubes remain connected to the Orbit Reflux Unit. The Orbit 6 module has a twist and click lid which supplies an inert atmosphere to all the tubes when in place. When the lid is removed, the tubes are automatically re-sealed and are free to be transported individually.

Orbit 12 (13mm dia, 10ml tubes)

2200032

The Orbit 12 unit holds 12 reaction tubes (10ml, 13mm diameter) allowing the bottom of the tube to be heated while the top is cooled to as a reflux condenser. The Orbit 12 module lifts in and out of the Orbit Reflux Unit (2200031), allowing the tubes to be freely transported as one whilst the water and gas tubes remain connected to the Orbit Reflux Unit. The Orbit 12 module has a twist and click lid which supplies an inert atmosphere to all the tubes when in place. When the lid is removed, the tubes are automatically re-sealed and are free to be transported individually.

Orbit Reflux Unit

2200031

The Orbit Reflux Unit locates on to the Atlas Hotplate (2101001), Hot and Cold Plate (2200047) and most third party stirrer hotplates. The Orbit 6 (2200033) and Orbit 12 (2200032) fit into the Orbit Reflux Unit. The Orbit Reflux Unit requires running cold water (or circulated coolant) to cool the condenser efficiently and a nitrogen or argon supply to create the inert atmosphere for the reaction tubes. As the Orbit 6 or Orbit 12 is lowered into the Orbit Reflux Unit, the nitrogen/argon connection is automatically made and the condenser section of the Orbit 6 or Orbit 12 is cooled.

Orbit Circulator (Julabo F200) 240V / 50Hz

2200059

New Orbit Circulator (Julabo F200) 115V / 60Hz

2200183

New Orbit Circulator (Julabo F200) 100V / 60Hz

2200220

The Julabo F200 is a re-circulating cooler for environmentally friendly cooling of the Orbit Reflux Unit (2200031). With a temperature range of 5 to 40째C, flow rate of up to 8 l/min and compact footprint of 19 x 35 x 41 cm, it is ideally suited for reflux condenser applications. For details on other Julabo circulators please see page 24.

Orbit Consumables Orbit 6 Reaction Tubes (Pack of 6) Pack of 6 reaction tubes for Orbit 6 (without caps or septa).

38

2200036


Orbit and Dry Baths

Orbit 6 Reaction Tube Caps (Pack of 6)

2200037

Pack of 6 caps (without septa) for Orbit 6 reaction tubes.

Orbit 6 Septa (Pack of 6)

2200038

Pack of 6 PTFE faced silicone septa to fit Orbit 6 Reaction Tube Caps.

Orbit 6 Stirrer Bars (Pack of 6)

2200040

Pack of 6 PTFE coated magnetic stirrer bars for Orbit 6 reaction tubes.

Orbit 12 Reaction Tubes (Pack of 12)

2200034

Pack of 12 reaction tubes for Orbit 12 (without caps or septa).

Orbit 12 Tube Caps with Septa (Pack of 12)

2200035

Pack of 12 Caps for Orbit 12 reaction tubes with PTFE faced silicone septa.

Orbit 12 Stirrer Bars (Pack of 12)

2200039

Pack of 12 PTFE coated magnetic stirrer bars for Orbit 12 reaction tubes.

Orbit Septa Opener (Pack of 6)

2200041

When the lid to the Orbit 6 or 12 is clicked into place, the Orbit Septa Openers push open the split septa in the caps of the reaction tubes. This allows the inert gas supply to flow into the reaction tube.

Orbit Gas Septa Ring (Pack of 5)

2200042

The Orbit Gas Septa Ring fits both the Orbit 6 (2200033) and Orbit 12 (2200032) and is a replaceable seal that allows reagent addition to or sample removal from the reaction tubes via a hypodermic needle. The Orbit Gas Septa Ring can be reused and rotationally repositioned to access previously un-pierced sections.

39


accessories & consumables Syrris offer a wide range of accessories and consumables for Atlas including stirrers, probes and glassware. A compatibility chart, showing which temperature probes and stirrers fit which reactors, is included for reference.

40


Accessories and Consumables

Glassware Jacketed Vessels Atlas Jacketed Vessels have been designed with a number of features to improve productivity and safety. Easy to use quick release oil connections. Chemically resistant zero dead volume bottom outlet. Easy to fit into the Clamp, using lift and lock mechanism. Sprung bottom outlet valve offers leak free operation. The jacket height extends to cover the stated reactor volume. O-ring sealing groove for vacuum operations. Torispherical, dished, conical and round bottom profiles available. Other designs such as split jacket and custom vessel profiles are available on request.

Jacketed Vessels - Round Bottom Round bottom vessels are traditionally used in most process development laboratories and give excellent mixing when used with most stirrers.

100ml - Round Bottom

2101525

250ml - Round Bottom

2101528

500ml - Round Bottom

2101530

1 litre - Round Bottom

2101532

2 litre - Round Bottom

2101534

New 3 litre - Round Bottom (Remote Mount Only)

2200261

New 5 litre - Round Bottom (Remote Mount Only)

2200253

Jacketed Vessels - Conical Bottom Conical bottom vessels allow low fill volumes to be used with good stirring.

250ml - Conical Bottom

2200019

500ml - Conical Bottom

2200020

1 litre - Conical Bottom

2200021

41


Accessories and Consumables

Jacketed Vessels - Torispherical Bottom Torispherical bottom vessels provide a good mimic to many pilot scale reactors.

New 50ml - Torispherical Bottom

2200184

New 100ml - Torispherical Bottom

2200185

New 250ml - Torispherical Bottom

2200186

New 500ml - Torispherical Bottom

2200187

New 1 litre - Torispherical Bottom

2200188

New 2 litre - Torispherical Bottom

2200189

Jacketed Vessels - Vacuum Jacket Atlas Vacuum Jacketed Vessels feature dish bottoms for mechanical strength whilst the vacuum jacket provides insulation and prevents both fogging and icing of the outer surface at low temperatures.

100ml - Vacuum Jacket - Dish Bottom

2200023

250ml - Vacuum Jacket - Dish Bottom

2200024

500ml - Vacuum Jacket - Dish Bottom

2200025

1 litre - Vacuum Jacket - Dish Bottom

2200026

2 litre - Vacuum Jacket - Dish Bottom

2200027

Jacketed Vessel 5 Litre Dished Bottom (Remote Mount Only)

2200074

Note that the 5 litre vessel can only be used with the Remote Mount for Jacketed Vessel Clamp (2101576).

Jacketed Filtration Vessel - 3 litre (Remote Mount Only)

2200048

The Atlas Jacketed Filtration Vessel has a removable bottom with a glass support to allow materials to be filtered through a filter paper, glass sinter or solid bed. The vessel is plastic coated. Other sizes are available on request.

42


Accessories and Consumables

Jacketed Vessel Lid (UK & EU)

2101030

Jacketed Vessel Lid (US)

2101594

The Atlas Vessel Lids fit all Atlas Jacketed Vessels and locate within the Jacketed Vessel Clamp (2101012). They seal against the top of the Jacketed Vessels using a Reaction Vessel Seal in FEP (2101016) or FFKM (2101543). They have 7 ports in total: 1 x vertical A24 centre port for the Stirrer Seal and Guide 3 x A19 ports designed for probes, sensors and condensers and are set at an angle of 15째 with a compound angle of 5째 to avoid clashing with items in other ports or the stirrer 1 x A29 port for larger probes, condensers or manual additions 2 x vertical GL18 ports designed to accept Atlas Jacketed Reactor Baffles or other devices with suitable adaptors The US version has longer cones to fit longer US ground glass joints.

Custom Lid for Jacketed Vessel

2200006

Custom lids, designed to individual specifications can be manufactured to match the requirements of users. Contact Syrris for further details.

50ml Round Bottom Flask

2101538

100ml Round Bottom Flask - Centre and 2 Angled Neck

2101539

250ml Round Bottom Flask - Centre and 2 Angled Neck

2101540

500ml Round Bottom Flask - Centre and 2 Angled Neck

2101541

1 Litre Round Bottom Flask - Centre and 2 Angled Neck

2101542

Syrris produce a range of glassware specially designed for use with Atlas Systems. A range of 3 neck flasks designed to be compatible with the Stacking Dry Bath (2101041) is available in volumes from 100ml to 1 litre. The centre port is a B24, compatible with the Stirrer Seal and Guide (2101011) and the side ports are B19 compatible with the small and medium Jacketed Coil Condensers. The 50ml flask has just one central joint.

Condenser - Small Jacketed Coil B19

2101591

Jacketed coil condensers offer very good surface area for condensation. The small condenser has a B19 connector, is 10cm long and has a surface area of 1.1x10-2m2. Suitable for vessels up to 250ml.

Condenser - Medium Jacketed Coil B19

2101590

Jacketed coil condensers offer very good surface area for condensation. The medium condenser has a B19 connector, is 16cm long and has a surface area of 4x10-2m2. Suitable for vessels up to 1 litre.

43


Accessories and Consumables

Condenser - Large Jacketed Coil B29

2101589

The Atlas large jacketed coil condenser offers very good surface area for condensation of 7x10-2m2. It has a B29 connector and features a bottom take-off which can be rotated in to the solvent path for distillation or out of the solvent path for reflux. Suitable for for vessels up to 2 litres.

6mm Dia RTD Probe Holder

2101546

8mm Dia RTD Probe Holder

2101547

9mm Dia RTD Probe Holder

2200132

The Atlas Probe Holder is fitted with an O-Ring to securely hold RTD probes in place whilst providing a liquid and gas tight seal.

2101015

Oil Pipes from Circulator to Oil Drain Unit (Pack of 2)

These Atlas Oil Pipes are insulated hoses and have M16 connections at each end. They are designed to fit between a circulator and the Oil Drain Unit (2101013). 2m length.

Oil Pipes from Reactor to Oil Drain Unit (Pack of 2)

2101014

These Atlas Oil Pipes are insulated hoses and have M16 connections at one end and a Connector - Oil Pipe to Jacketed Vessel (2200018) at the other. They are designed to be used with a jacketed reactor and the Oil Drain Unit (2101013). 0.5m length.

Connector - Oil Pipe to Jacketed Vessel (Pack of 2)

2200018

This part allows the quick connection and disconnection of Oil Pipes to Atlas Jacketed Vessels. It also contains a thermowell enabling easy and accurate measurement of the circulator fluid temperature at the input and/or output of the jacketed reactor. This connector screws onto an Oil Pipe using a regular M16 thread then connects to an Atlas Jacketed Reactor without the need for tools. The thermowell accepts the RTD Probe - Stainless Steel 100mm x 3mm (2101593). Note that the M16 fitting and thermowell positions are interchangeable to enable straight or 90째 connection between the Jacketed Vessel and Oil Pipe. This part is included in Oil Pipes from Reactor to Oil Drain Unit (2101014).

New Connector - Oil Pipe to Hot and Cold Plate (Pack of 2)

Velcro Oil Connector Insulator (Pack of 2)

2200181

2200008

The flexible Velcro Oil Connector Insulators can be used to reduce condensation or ice build-up at connections. Each insulator can be wrapped around a connector and secured using the Velcro fastener. Two or more insulators can be "daisy chained" together to surround larger diameter objects such as reactors.

44


Accessories and Consumables

Reaction Vessel Drip Tray

2101039

This 2 litre Reaction Vessel Drip Tray can be fitted into the central cavity of the Base Unit (2101000) to catch any spills from a jacketed reactor.

New Node Clip

2200200

The Node Clip allows the Node Extension (2101023) sockets to be clipped to the Support Rods (2101009). This is useful when using more than one node.

Support Rods (Pack of 2)

2101009

A pair of Support Rods fit in the rear of the Base Unit (2101000). The Oil Drain Unit (2101013), Clamp (2101040), Jacketed Vessel Clamp (2101012), etc. are all held by the Support Rods. It is also possible to fit a further pair of Support Rods to the top of the Jacketed Vessel Clamp to hold other apparatus.

Stirrers

Stirrer - PTFE 2 Blade Centrifugal 300mm

1802059

Stirrer - PTFE 4 Blade Propeller 300mm x 40mm dia

1802014

Stirrer - PTFE 4 Blade Propeller 400mm x 40mm dia

1802015

Stirrer - PTFE 4 Blade Propellor 500mm x 40mm dia

1802016

Stirrer - PTFE Anchor 300mm x 80mm dia

1802056

Stirrer - PTFE Anchor 400mm x 80mm dia

1802057

Stirrer - PTFE Anchor 500mm x 80mm dia

2200087

Stirrer - PTFE 3 Blade Retreat Impeller 400mm x 75mm dia

2101585

Stirrer - PTFE 3 Blade Retreat Impeller 500mm x 75mm dia

2200124

New Stirrer - PTFE 3 Blade Retreat Impeller 650mm x 75 dia

2200176

New Stirrer - Glass 4 Blade Propellor 300mm x 27mm

2200285

New Stirrer - Glass Anchor 300m x 36mm

2200286

Stirrer - Glass 3 Blade Retreat Impeller Cut Length x 45mm dia

2101523

Stirrer - Glass 3 Blade Retreat Impeller Cut Length x 75mm dia 2200085 Atlas PTFE stirrers have steel shafts for strength and a thick PTFE coating for chemical resistance. The Atlas glass stirrers are cut to length by Syrris before shipment (please specify reaction vessel and desired stirring height from the bottom of the vessel when placing an order). Glass stirrers are required for work under vacuum. All Atlas Stirrers are compatible with the Stirrer Seal and Guide (2101011). Custom profile stirrers are available on request.

45


Accessories and Consumables

Probes

New

RTD Probe - PTFE Coated 100mm x 6mm

2101586

RTD Probe - PTFE Coated 200mm x 6mm

2101582

RTD Probe - PTFE Coated 300mm x 8mm

2101583

RTD Probe - PTFE Coated 400mm x 8mm

2101584

RTD Probe - PTFE Coated 500mm x 9mm

2200122

RTD Probe - PTFE Coated 600mm x 9mm

2200262

A range of different size PTFE coated RTD Probes is available. These are fitted with a specialist connector for connection to a Temperature Node (2101021). Note that the RTDs have various diameters and should be used with the corresponding probe holder. The 100mm probe (2101586) is ideal for use within condensers or for headspace temperature measurement. See the compatibility chart at the back of this catalogue to match reaction vessel with probe length.

2101593

RTD Probe - Stainless Steel 100mm x 3mm for Dry Baths

The 100 x 3mm stainless steel RTD probe can be used with the Stacking Dry Bath (2101041), Triple Dry Bath (2101042) and Orbit Systems for accurate temperature control. It can also be used with the Connector - Oil Pipe to Jacketed Vessel (2200018) to monitor the temperature of coolant fluid as it enters the reactor jacket. This is used in Heat Flow Calorimetry (HFC).

New

New

New

RTD Probe - FEP Coated SS Quick Response 300mm

2200144

RTD Probe - FEP Coated SS Quick Response 400mm

2200145

RTD Probe - FEP Coated SS Quick Response 500mm

2200146

The quick response RTDs connect to a Temperature Node (2101021) in the same way as a regular RTD. The quick response RTDs have a thinner, chemically resistant coating and are designed for use with the Atlas Calorimeter (see page 13). These RTDs come with a probe holder.

pH Probe - 400mm with Swivel Adaptor

2200029

pH Probe - 200mm x 8mm with B19 Holder

2200029 2200054

These pH Probes connect to the pH and Temperature Node (2200071). The swivel adaptor allows its angle to be adjusted within a jacketed reactor. These combination probes have a AgCl reference, temperature range of 0-100째C and a pH range of 0-14.

New Turbidity Probe - 400mm

2200156

The Turbidity Probe can be used as a simple crystallization point detector, or in more complex studies of metastable crystallization zones, secondary nucleation and polymorphism issues. It requires a Turbidity Node (2200157) and has a two point calibration.

46


Accessories and Consumables

New Heater Rod for Calorimetry - 25W, 300mm FEP Coated

2200142

New Heater Rod for Calorimetry - 50W, pH Probe - 200mm x 8mm with B19500mm Holder FEP Coated

2200143 2200029

These heater rods are designed for the Atlas Calorimeter. They are used for Power Compensation Calorimetry (PCC) and for calibration in Heat Flow Calorimetry (HFC).

Accessories

Oil Pipe Tidy

2200046

The Oil Pipe Tidy fits on the Jacketed Vessel Clamp (2101012) and is used to seal the spare end of the Oil Pipes from Reactor to Oil Drain Unit (2101014) when changing reactor, tidying them to an elevated position. This avoids residual oil in the pipes dripping onto the fume cupboard floor and acts as a safety feature should the circulator be switched on accidentally. There is also a location to store the Scorpion Overhead Stirrer (2101004) when not in use.

New Baffles for 0.5 litre Torispherical Jacketed Vessel (Pack of 2) New Baffles for 1 litre Torispherical Jacketed Vessel (Pack of 2)

Baffles for 2 litre Round Bottom Jacketed Vessel (Pack of 2)

2200171

2200170

2101580

These baffles locate in the standard Jacketed Vessel Lids (2101030 and 2101594) and are designed to increase stirring efficiency within a large reactor and mimic conditions found within pilot scale vessels. Custom sizes and formats are available on request.

Isolation Ball Valve for Circulator Pipe M16x1

1802039

An isolation valve for closing off oil pipes with M16 fittings.

New Jacketed Vessel Earth Strap

2200201

This strap fits around Vacuum Jacketed Vessels to avoid static build up.

Sintered Dip Tube - Glass 450mm x 8mm No. 3 Sinter

2200202

Designed for bubbling gas into a jacketed reactor.

New

Liquid Feed Adaptor - B19 to Glass Tube 8mm x 200mm

New GL14 Plastic Screw Cap with Aperture New GL14 PTFE Faced Silicone 6mm Sealing Ring New GL18 Plastic Screw Cap with Aperture

2200158 2101517

1802022

2101516

New GL18 PTFE Faced Silicone 6mm Sealing Ring

1802023

New GL18 PTFE Faced Silicone 8mm Sealing Ring

1802024

47


Accessories and Consumables

New GL18 to Male B19 Adapter

2101519

New GL14 to Male B19 Adapter

2101518

New GL14 to B19 Joint - Glass Adapter

2200177

New

B29 Glass Stopper

1802066

New

B19 Glass Stopper

1802067

Base to Circulator Serial Cable (RJ11 to DB9 Male)

2400214

A 9 pin D-type to RJ11 cable for connecting Circulators to the Base Unit. The corresponding RS232 or null modem cable required to connect from this cable to a module will be supplied with the module if purchased from Syrris.

New

Comms Cable - IKA Eurostar Overhead Stirrer

2200125

New

Comms Cable - IKA Werke Peristaltic Pump

2200126

New

Comms Cable - Watson Marlow Peristaltic Pump 520Du

2200127

New

Comms Cable - Mettler SevenEasy pH Meter

2200128

New

Comms Cable - Julabo Circulator

2200129

New

Comms Cable - Huber Nuevo Circulator

2200130

New

Comms Cable - Watson Marlow Peristaltic Pump 323Du

2200133

New

Comms Cable - Haake DC50 Circulator

2200134

New

Comms Cable - Lauda Proline Circulator

2200135

New

Comms Cable - IKA / Chemglass Overhead Stirrer

2200167

New

Comms Cable - TTI Power Supply for Calorimetry

2200152

New

Comms Cable - Heidolph Overhead Stirrer

2200256

New

Comms Cable - Huber Ministat CC230/CC240

2200155

A range of comms cables are available for connecting RS232 controlled devices to the PC software via Atlas Ports. Other cables are available on request.

New

New

RS232 Extension Cable - 5m

2200168

RS232 Null-Modem Cable - 5m

2200169

48


Accessories and Consumables

Consumables New Set of Seals for Stirrer Seal and Guide

2101017

This part includes a full set of consumables and wearing parts for the Stirrer Seal and Guide (2101011), including: 1 x PTFE Sprung Stirrer Shaft Seal 1 x Carbon filled PTFE Stirrer Shaft Seal Holder 1 x PEEK Static Seal 1 x Viton O-ring for Static Seal 1 x Seal Spring 2 x FFKM Stirrer Guide O-ring

New Stirrer Guide Replacement Seals (Pack of 5)

2200161

A set of five replacement FFKM O-rings for use at the base of the Stirrer Seal and Guide (2101011).

New Jacketed Vessel to Oil Pipe Seals (Pack of 2 Pairs)

2200107

Two pairs of replacement seals that fit inside the Connector - Oil Pipe to Jacketed Vessel (2200018).

Reaction Vessel Seal (FEP Coated Silicone)

2101016

A replacement FEP coated silicone O-ring for use with the Jacketed Reactor and Lid (2101030 / 2101594).

2101543

Reaction Vessel Seal (FFKM) A replacement FFKM o-ring for use with the Jacketed Reactor and Lid (2101030 / 2101594).

FFKM is the sealing material that offers the highest

chemical resistance.

Bottom Outlet Valve - Unsprung 9mm

2200030

New Bottom Outlet Valve - Sprung 9mm (Jacketed Vessels)

2200150

New Bottom Outlet Valve - Sprung 9mm (Vacuum Jacketed)

2200193

Replacement PTFE Reaction Vessel Bottom Outlet Valves for use with Jacketed Reactors. This valve comes complete with FFKM O-rings. The sprung versions account for thermal expansion and contraction, minimising leaks.

Bottom Outlet Valve Bottom Seal (FFKM)

1802152

Replacement FFKM O-ring for the lower seal of a jacketed vessel bottom outlet valve. FFKM is the sealing material that offers the highest chemical resistance.

Bottom Outlet Valve Top Seal (FFKM)

1802042

Replacement FFKM O-ring for the upper seal of a jacketed vessel bottom outlet valve. FFKM is the sealing material that offers the highest chemical resistance.

49


Accessories and Consumables

Circulator Fluid (-40 to +204°C) - 5 Gallons

1802036

5 Gallons (18.92ltrs) of circulator fluid recommended by Syrris and approved by most major recirculator manufacturers. This fluid is suitable for operation in the range -40 to +204°C (flash point >+40°C).

New Circulator Fluid (+20 to +250°C) - 10 litres

2200163

10 litres of circulator fluid recommended by Syrris and approved by most major recirculator manufacturers. This fluid is suitable for operation in the range +20 to +250°C (flash point >+270°C).

New Circulator Fluid (-50 to +105°C) - 10 litres

2200164

10 litres of circulator fluid recommended by Syrris and approved by most major recirculator manufacturers. This fluid is suitable for operation in the range -50 to +105°C (flash point >+110°C).

New Circulator Fluid (-20 to +180°C) - 10 litres

2200165

10 litres of circulator fluid recommended by Syrris and approved by most major recirculator manufacturers. This fluid is suitable for operation in the range -20 to +180°C (flash point >+175°C).

3 Roller Extension Head for Watson Marlow 323/DU/D

1802046

Extension pump head for multi-channel pumping.

Fluorinated Tubing 1.6mm bore (5m)

1802047

Fluorinated Tubing 3.2mm bore (5m)

1802048

Fluorinated Tubing 4.8mm bore (5m)

1802049

Syrris provides a range of tubing suitable for use in peristaltic pumps. This chemically resistant tubing (contact Syrris for compatibility details) is available in a range of sizes for different pumping requirements. This tubing is ideal for use with Watson Marlow Pumps (1802045).

New

2 Port Valve (PTFE/PCTFE) for Atlas Syringe Pump

2200089

New

3 Port Valve (PTFE/PCTFE) for Atlas Syringe Pump

2200090

New

4 Port Valve (PTFE/PCTFE) for Atlas Syringe Pump

2200091

New

6 Port Valve (PTFE/PCTFE) for Atlas Syringe Pump

2200092

Various valve types depending on number of inputs and outputs required for Atlas Syringe Pump (2200072).

50


Accessories and Consumables

New

Syringe for Atlas Syringe Pump - 50µl

2200093

New

Syringe for Atlas Syringe Pump - 100µl

2200094

New

Syringe for Atlas Syringe Pump - 250µl

2200095

New

Syringe for Atlas Syringe Pump - 500µl

2200096

New

Syringe for Atlas Syringe Pump - 1ml

2200097

New

Syringe for Atlas Syringe Pump - 2.5ml

2200098

New

Syringe for Atlas Syringe Pump - 5ml

2200099

Various sized syringes for Atlas Syringe Pump (2200072). Syringes are made from glass with PTFE plungers for excellent chemical resistance.

New

Pipe End Fittings for Atlas Syringe Pump - Tefzel 1.6mm

2200198

A pack of 10 pairs of flangeless ferrules and 1/4-28 fittings for 1.6mm pipe.

New

Pipe End Fittings for Atlas Syringe Pump - Tefzel 3.2mm

2200199

A pack of 10 pairs of flangeless ferrules and 1/4-28 fittings for 3.2mm pipe.

51


Atlas Accessories Compatibility Chart Stirrers

Key

PTFE 2 Blade Centrifugal 300mm

PTFE 4 Blade Propeller 300mm x 40mm dia

PTFE 4 Blade Propeller 400mm x 40mm dia

PTFE 4 Blade Propeller 500mm x 40mm dia

PTFE Anchor 300mm x 80mm dia

PTFE Anchor 400mm x 80mm dia

PTFE Anchor 500mm x 80mm dia

PTFE 3 Blade Retreat Impeller 400mm x 75mm dia

PTFE 3 Blade Retreat Impeller 500mm x 75mm dia

PTFE 3 Blade Retreat Impeller 650mm x 75mm dia

Glass 4 Blade Propeller 300m x 27mm

Glass Anchor 300mm x 36mm

Glass 3 Blade Retreat Impeller Cut Length x 45mm dia

Glass 3 Blade Retreat Impeller Cut Length x 75mm dia

1802059

1802014

1802015

1802016

1802056

1802057

2200087

2101585

2200124

2200176

2200285

2200286

2101523

2200085

Ideally Suited Suited Not Suited

*

Stirrers

Requires Remote Mount

Reactors

Part number

Jacketed Vessel 100ml Round Bottom

2101525

Jacketed Vessel 250ml Round Bottom

2101528

Jacketed Vessel 500ml Round Bottom

2101530

Jacketed Vessel 1 litre Round Bottom

2101532

Jacketed Vessel 2 litre Round Bottom

2101534

Jacketed Vessel 3 litre Round Bottom*

2200261

Jacketed Vessel 5 litre Round Bottom*

2200253

Jacketed Vessel 50ml Torispherical Bottom

2200184

Jacketed Vessel 100ml Torispherical Bottom

2200185

Jacketed Vessel 250ml Torispherical Bottom

2200186

Jacketed Vessel 500ml Torispherical Bottom

2200187

Jacketed Vessel 1 litre Torispherical Bottom

2200188

Jacketed Vessel 2 litre Torispherical Bottom

2200189

Jacketed Vessel 5 litre Dished Bottom*

2200074

Jacketed Vessel 250ml Conical Bottom

2200019

Jacketed Vessel 500ml Conical Bottom

2200020

Jacketed Vessel 1 litre Conical Bottom

2200021

Jacketed Vessel 100ml Vacuum Jacket

2200023

Jacketed Vessel 250ml Vacuum Jacket

2200024

Jacketed Vessel 500ml Vacuum Jacket

2200025

Jacketed Vessel 1 litre Vacuum Jacket

2200026

Jacketed Vessel 2 litre Vacuum Jacket

2200027

Jacketed Filtration Vessel 3 litre*

2200048

50ml Round Bottom Flask

2101538

100ml Round Bottom Flask

2101539

250ml Round Bottom Flask

2101540

500ml Round Bottom Flask

2101541

1 litre Round Bottom Flask

2101542

52


Atlas Accessories Compatibility Chart Probes and Heater Rods

RTD Probe - PTFE Coated 100mm x 6mm

RTD Probe - PTFE Coated 200mm x 6mm

RTD Probe - PTFE Coated 300mm x 8mm

RTD Probe - PTFE Coated 400mm x 8mm

RTD Probe - PTFE Coated 500mm x 9mm

RTD Probe - PTFE Coated 600mm x 9mm

RTD Probe - Stainless Steel 100mm x 3mm - Dry Baths

RTD Probe - FEP Coated SS Quick Response 300mm

RTD Probe - FEP Coated SS Quick Response 400mm

RTD Probe - FEP Coated SS Quick Response 500mm

pH Probe - 400mm with Swivel Adaptor

pH Probe - 200mm x 8mm with B19 Holder

Turbidity Probe - 400mm

Heater Rod for Calorimetry - 25W, 300mm FEP Coated

Heater Rod for Calorimetry - 50W, 500mm FEP Coated

2101586

2101582

2101583

2101584

2200122

2200262

2101593

2200144

2200145

2200146

2200029

2200054

2200156

2200142

2200143

Key Ideally Suited Suited Not Suited

* Probes and Heater Rods

Requires Remote Mount

Reactors

Part number

Jacketed Vessel 100ml Round Bottom

2101525

Jacketed Vessel 250ml Round Bottom

2101528

Jacketed Vessel 500ml Round Bottom

2101530

Jacketed Vessel 1 litre Round Bottom

2101532

Jacketed Vessel 2 litre Round Bottom

2101534

Jacketed Vessel 3 litre Round Bottom*

2200261

Jacketed Vessel 5 litre Round Bottom*

2200253

Jacketed Vessel 50ml Torispherical Bottom

2200184

Jacketed Vessel 100ml Torispherical Bottom

2200185

Jacketed Vessel 250ml Torispherical Bottom

2200186

Jacketed Vessel 500ml Torispherical Bottom

2200187

Jacketed Vessel 1 litre Torispherical Bottom

2200188

Jacketed Vessel 2 litre Torispherical Bottom

2200189

Jacketed Vessel 5 litre Dished Bottom*

2200074

Jacketed Vessel 250ml Conical Bottom

2200019

Jacketed Vessel 500ml Conical Bottom

2200020

Jacketed Vessel 1 litre Conical Bottom

2200021

Jacketed Vessel 100ml Vacuum Jacket

2200023

Jacketed Vessel 250ml Vacuum Jacket

2200024

Jacketed Vessel 500ml Vacuum Jacket

2200025

Jacketed Vessel 1 litre Vacuum Jacket

2200026

Jacketed Vessel 2 litre Vacuum Jacket

2200027

Jacketed Filtration Vessel 3 litre*

2200048

50ml Round Bottom Flask

2101538

100ml Round Bottom Flask

2101539

250ml Round Bottom Flask

2101540

500ml Round Bottom Flask

2101541

1 litre Round Bottom Flask

2101542

Headspace / distillation

53


custom laboratory reactor systems What are Custom Reactor Systems? Syrris offer a wide range of Custom Reactor Systems for increased user specificity. The range of custom reactor systems are available from 10ml to 250 litres. They are designed and built to your specifications. Complete systems including reactors, pressure reactors, stirrers, circulators, RTDs, pumps, sensors, etc. can be configured using virtually any manufacturer’s apparatus. Choose from either manual control or total automation using Atlas PC Software. Custom Reactor Systems

Custom Reactor System benefits

With over 200 man years of combined experience, Syrris chemists and engineers manufacture the highest quality customized systems. They are assembled to your specification and rigorously tested at our facility before installation at your laboratory.

Wide volume range: Reactors from 100ml to 250 litres in glass, stainless steel or Hastelloy. Wide temperature and pressure range: Reactions can be heated to 380°C and pressurised up to 100 bar. Safe: Warning alarms and emergency cut-off values or actions can be defined.

Case Studies

Control: High torque stirring including torque measurement. Measured: Dosing of gas, liquid or powder, with fully automated or manual control.

Case Study 1: 20 litre automated synthesis system for a world leading pharmaceutical company. This included high torque stirring, volumetric liquid addition and temperature monitoring.

Pressurized: Reactions such as fully controlled hydrogenations and carbonylations can be performed.

Case Study 2: Two interchangeable reactors (5 and 10 litres) with speed and torque monitoring. Temperature dependant gravimetric dosing with full data-logging.

Integrated: Can provide integrated pH and liquid control. Flexible Control: Manual or fully automated for unattended operation.

Pre-configured Apparatus Virtually any RS232 device with ASCII communications can be configured. The current list of pre-configured devices include:

Easy to use software: Drag and drop icons allow recipes to be created, edited and run intuitively. Empowering: Virtually any manufacturer’s apparatus can be configured into a system using the software.

Balances

Circulators

Powerful: Apparatus such as pumps and balances can be combined in an intelligent fashion (e.g. enabling gravimetric dosing or dosing to maintain a pH).

Flow Meters

Temperature Sensors

Overhead Stirrers

Turbidity

pH Meters

Pumps

FBRM

Vacuum Controllers

Automatic data logging: All responses such as temperature, stirrer speed, pH, mass flow, etc. can be graphically displayed in real time and are continually saved to one .csv file.

FTIR

Left: The Atlas Software’s intuitive display Above: High pressure reactor Right: 10 litre Custom Reactor System with software control

Customized products - flexible solutions www.syrris.com/custom-reactor-systems.aspx

54


Flow Chemistry Flow chemistry (sometimes referred to as pluglow, microchemistry, or continuous flow chemistry) offers exciting opportunities to integrate traditionally separate processes and increase the pace of discovery and development. Flow chemistry has emerged as a new and productive technology for Research and Development Chemists. Syrris offer a range of flow chemistry products from entry level systems (FRX) to fully automated microreactor reactor systems (Africa). Syrris Flow Chemistry Products

frx

africa

flow chemistry toolkit

automated flow chemistry Africa is the most sophisticated and flexible microreactor system available. Reaction optimization, library synthesis or preparative synthesis can be performed with work-up and analysis in an entirely automated fashion.

The FRX system from Syrris makes flow chemistry cost effective, easy to use, understandable and affordable. FRX is made up of a number of modules that can be connected together to form simple yet powerful flow chemistry systems.

www.syrris.com/FRX.aspx

www.syrris.com/AFRICA.aspx

What are the benefits of using flow chemistry? Faster reactions: Increase reaction rates over 100

Safer reactions: Only small amounts of material react

fold by superheating reactions significantly above

at any time, minimising exotherms and the quantity

reflux e.g. dichloromethane to 100°C, acetonitile to

of any hazardous intermediates.

150°C and water to 170°C

Rapid development: Reaction time, temperature and

Cleaner reactions: Reduced impurities via excellent,

equivalents can be rapidly varied using only mg of

reproducible reaction control and optional use of

substrate.

solid phase reagents/catalysts/ scavengers.

Scale-up: Production rates up to kg overnight.

Inline aqueous work-up: The Flow Liquid Liquid

Wide temperature range: Heat reactions up to

Extraction Module (FLLEX) enables two immiscible

300°C or cool down to -20°C.

phases to be mixed and separated in flow,

Chemically resistant: Glass and PTFE reactors allow a

immediately following the reaction.

wide range of chemistry.

Reactions not possible with batch synthesis:

Compact size: Systems fit easily into standard fume

Extremely quick reaction times, reagent additions,

cupboards.

temperature changes and quenches are possible.

55


Syrris Ltd. Unit 1, Anglian Business Park, Orchard Road Royston, Hertfordshire, SG8 5TW, United Kingdom

T: +44 (0)1763 242555 F: +44 (0)1763 246125 E: info@syrris.com W: www.syrris.com Syrris Inc. (North America) 29 Albion Place Charlestown, MA 02129

Syrris Japan, Inc. 2-5-1-220, Oakashi-cho Hyogo, Japan 673-0891

Syrris India. 420 / 421, Corporate Avenue, Sonawala Road, Goregaon, East Mumbai 400 063

T: 617 848 2997 F: 617 532 1033 E: info-usa@syrris.com W: www.syrris.com

T: 078 919 5909 F: 078 977 8242 E: info@syrris.co.jp W: www.syrris.co.jp

T: +91 22 2686 4410 E: info@syrris.com W: www.syrris.com

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Atlas Catalogue