hydride reduction and wolf krishnner reduction friedel craft’s reaction, Perkin reaction, Cannizzaro reaction. Mannich Reaction 3. REACTIVE INTERMEDIATES AND FREE RADICALS: Introduction, Generation, stability and Reaction of the following intermediates: Carbocations, Carbanions, Carbenes, Nitrenes,Benzynes, Type of reactions: An Overview. Free radicals, Free radical scavengers and their applications. 4. CARBONIUM ION REARRANGEMENTS: Pinacol-Pinacolone, wignerMeerwein, Wolf, Hofmann and Beckmann rearrangements. 5. CARBANIONS: Condensation reaction (Aldol condensation Favorskii rearrangement; writing reaction)
PHARM 323 [Lab.] Cr. Hr.: 01
PHARMACEUTICAL CHEMISTRY-II (ORGANIC-I) Marks: 50
NOTE: - Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g.Organic Preparations: Benzoic acid, Aspirin, Acetanilide, Iodoform, Nitrophenol, 3nitrophthalic acid, Benzhydrol and 2,4-Dinitrochlorobenzene.
R ec o mme n d e d B o o k s:
1. Peter Sykes, A guide Book to Mechanism in Organic Chemistry, th Longman, New York, 6 Ed, 1991. 2. E L Eliel, Stereochemistry of Carbon Compounds, Tata McGraw- Hill, New Delhi, 1992. 3. Rehman and M Younis, Organic Chemistry for B.Sc. students, Ilmi Kitab Khana, Lahore, 1997. 4. L Finar, Organic Chemistry Vol I, Person Education Asia, 6th Ed., New Delhi, 2001. 5. Raj K Bansel, Organic Reaction Mechanism, Tata McGraw-Hill, New Delhi, 1992. 6. Furaiss Brian, Practical Organic Chemistry, 5th Ed., ELBS, London. 7. Sykes A P, Guide Book to Mechanism in Organic Chemistry, 6th Ed., Lonsmen Co, UK, 2008. 8. Roberts J D and Caserio M C, Basic Principles of organic Chemistry,