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o ur 4 1 ST ye ar

MLK J R . RE ME MB ERE D

IN S TOCKH OL M

Covering Homewood, East Baltimore, Peabody,

Martin Luther King III will be

Astrophysicist Adam Riess

SAIS, APL and other campuses throughout the

the featured speaker at event

receives his Nobel Prize from

Baltimore-Washington area and abroad, since 1971.

honoring his father, page 4

the King of Sweden, page 12

December 19, 2011

The newspaper of The Johns Hopkins University P U B L I C

O U T R E A C H

Confronting gender-based violence

Volume 41 No. 16

P O L I C Y

Studying the city’s demographic transformation

By Greg Rienzi

The Gazette

Continued on page 5

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will kirk / homewoodphoto.jhu.edu

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ancy Glass has spent the better part of two decades addressing intimate partner violence and violence against women. Glass, an associate professor of community public health nursing in the School of Nursing, has seen Free online firsthand the devastating impacts of this growing global course will health crisis. An estimated one train health out of three women worldwide will be workers physically or sexually assaulted in their worldwide lifetime, according to the World Health Organization. Roughly 50 percent of sexual assaults are committed against girls under age 16. In 2002, WHO estimated that 150 million girls and 74 million boys under the age of 18 had experienced some form of sexual violence. “We are seeing too often that the first sexual encounter is forced, and often before the age of 15,” Glass said. “And this is not just occurring in conflict settings but areas around the globe.” A major obstacle in the fight against gender-based violence, Glass said, is that victims are afraid to come forward. “Women live with this silently,” she said. “They feel there is no help.” Johns Hopkins wants to make sure that these victims have a sympathetic, and knowledgeable, ear to turn to. In an effort to train professionals to confront this major health issue, the School of Medicine’s Center for Clinical Global Health Education, in conjunction with the School of Nursing’s Center for Global Nursing, will offer Confronting Gender-Based Violence, a distance-education course that began enrollment on Dec. 1. The seven-week online training course is an interactive program aimed at improving clinical and psychosocial care for women and men who are survivors of and/or at risk for gender-based violence.

Groups of students in the Master of Public Policy program looked at five diverse areas to determine how they have changed over three decades. Above, Whitney Moyer, Ernest Le and Bonnie O’Keefe in Otterbein.

IPS students fan out into Baltimore neighborhoods to examine changes By Greg Rienzi

The Gazette

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hile Baltimore continues to dwindle in population size, many neighborhoods with high ethnic and racial change are growing, triggered in part by a significant increase in the number of Hispanic and Asian residents, according to a study by 62 students in the Institute for Policy Studies’

Master of Public Policy program. For the annual Baltimore project in a course called Policy Analysis for the Real World, students examined the demographic transformation in the city’s neighborhoods during the past three decades. Continued on page 10

R E S E A R C H

Scientists develop model for TB-related blindness B y D av i d M a r c h

Johns Hopkins Medicine

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orking with guinea pigs, tuberculosis experts at Johns Hopkins and elsewhere have closely mimicked how active but untreated cases of the underlying lung infection lead to permanent eye damage and blindness in people. Lead study investigator Petros Karakousis, a Johns Hopkins infectious disease specialist, says that the new animal model should

In Brief

A Christmas Eve tradition; lacrosse schedule announced; Medical Student Research Day

12

hasten development of a badly needed early diagnostic test for the condition. Symptoms of ocular TB—vision loss, and redness and pain in the eye—are often indistinguishable from symptoms of other chronic infections and inflammatory conditions, including toxoplasmosis and sarcoidosis, a similarity that can often lead to selecting the wrong therapy. “TB infection can be active in the eyes even in the absence of lung symptoms, so there are usually long delays in diagnosis, and by this time, it’s too late for tens of thou-

C A L E N D AR

‘Patents in the Clouds’; Carey Business School information sessions; blood drive

sands of people who are already going blind due to permanent inflammatory damage to the inner lining of the eyes,” said Karakousis, an assistant professor at the Johns Hopkins University School of Medicine. The scenario, he notes, is especially true in the United States and Europe, where TB is far less common than in developing countries, where most of the 9 million new infections occur each year. Most new cases in the United States occur in people whose Continued on page 4

10 Job Opportunities 10 Notices 11 Classifieds


2 2011 2 THE THE GAZETTE GAZETTE •• December August 15,19, 2011

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I N   B R I E F

Join in a Christmas Eve tradition By Dennis O’Shea

University Administration

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n outdoor meeting. On Dec. 24. In a graveyard. Are they crazy? A hardy (and undoubtedly well-insulated) group of Johns Hopkins staff, faculty, alumni and supporters will gather in Baltimore’s Green Mount Cemetery at 10 a.m. on Christmas Eve. They’ll be there to honor the man who made it all possible: Mr. Johns Hopkins. Hopkins, who is buried at Green Mount, died the morning of Dec. 24, 1873, leaving $7 million in his will to establish the university and hospital that bear his name. It was, to that time, the nation’s largest philanthropic bequest. “We gather at his grave to remember a great man and a great act of generosity,” said Ross Jones, vice president and secretary emeritus of the university. Jones arranged the first graveside commemoration in 1973, the centennial of Mr. Hopkins’ demise, and

Lacrosse season opens at home with Feb. 17 Towson game

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acrosse coach Dave Pietramala last week announced the Blue Jays’ 2012 schedule, which includes eight home games, the Konica Minolta Inside Lacrosse Face-Off, Big City Classics and a return by Army to Homewood Field for JHU’s annual Homecoming game. The Jays will prep for the challenging schedule with scrimmages against Penn State and Cornell in early February, and the 14 regular season games will match the school record for most in a season. The 2012 season opens with a three-game home stand, starting with Towson on Feb. 17 and followed by Delaware on Feb. 21 and Siena on Feb. 25. The Blue Jays then make their first trip to Princeton since 2005 to take on the Tigers on March 2. Other regular-season opponents are Manhattan, Syracuse, Virginia, North Carolina, Albany, Maryland, Navy and Loyola. To see the complete schedule, go to hopkinssports.com.

Medical Student Research Day planned for Jan. 6 in AMEB

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he fourth annual Medical Student Research Day is set for Friday, Jan. 6, in the Armstrong Medical Education Building, with Jeremy Sugarman, deputy director of the Johns Hopkins Berman Institute of Bioethics, giving the keynote address. More than 120 students are expected to present their findings to classmates and

Editor Lois Perschetz Writer Greg Rienzi Production Lynna Bright Copy Editor Ann Stiller Photography Homewood Photography

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A d v e rt i s i n g The Gazelle Group Business Dianne MacLeod C i r c u l at i o n Lynette Floyd W e bm a s t e r Lauren Custer

has organized similar events annually since 1998, the 125th anniversary. “What this one man did has meant so much for the world,” Jones said. “More personally, his legacy also means so much to all of us who have had the privilege to work, study or heal at the institutions he founded. It seems only right to set aside a few minutes every Dec. 24 to remember him and thank him.” The brief, informal ceremony includes remembrances of Mr. Hopkins, the presentation of a wreath and brief remarks. This year, Stephen C. Achuff, a professor of cardiology at the School of Medicine, will highlight aspects of the history of the Johns Hopkins Medical Institutions. To reach the gravesite, enter Green Mount Cemetery at the main gate along Greenmount Avenue, about five blocks south of North Avenue. Drive straight up the hill and park near the crest. To read Mr. Hopkins’ obituary from the Dec. 25, 1873, edition of The Baltimore Sun, go to www.jhu.edu/125th/links/obit.html.

faculty at the event, which begins at noon with a poster session, followed by podium presentations and a second poster session. Sugarman’s talk at 4:30 p.m. will be followed by an award ceremony. About two dozen faculty members will serve as judges, and prizes range from $500 to $2,000. For specific times, see the calendar in this issue.

JHU student takes top spot in nationwide ‘green’ challenge

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aychel Santo, a sophomore double majoring in public health studies and global environmental change and sustainability, has won the national Project Green Challenge competition, a 30-day lifestyle initiative run by Teens Turning Green, a student-led initiative. She competed for the award in San Franciso with 12 other finalists, who included the Johns Hopkins sister team Nicole and Hannah Jiam. Santo is the founding president of Real Food Hopkins and recently worked with the university’s Office of Facilities Management to create a community garden on the Johns Hopkins at Eastern campus.

This issue of ‘Gazette’ is last for semester; next will be Jan. 9

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his is the last issue of The Gazette for the semester; the next issue will be published on Jan. 9. The deadline for calendar and classified submissions is Friday, Dec. 30.

Contributing Writers Applied Physics Laboratory  Michael Buckley, Paulette Campbell Bloomberg School of Public Health Tim Parsons, Natalie Wood-Wright Carey Business School Andrew Blumberg, Patrick Ercolano Homewood Lisa De Nike, Amy Lunday, Dennis O’Shea, Tracey A. Reeves, Phil Sneiderman Johns Hopkins Medicine Christen Brownlee, Stephanie Desmon, Neil A. Grauer, Audrey Huang, John Lazarou, David March, Vanessa McMains, Ekaterina Pesheva, Vanessa Wasta, Maryalice Yakutchik Peabody Institute Richard Selden SAIS Felisa Neuringer Klubes School of Education James Campbell, Theresa Norton School of Nursing Kelly Brooks-Staub University Libraries and Museums Brian Shields, Heather Egan Stalfort

The Gazette is published weekly September through May and biweekly June through August for the Johns Hopkins University community by the Office of Communications and Public Affairs, Suite 540, 901 S. Bond St., Baltimore, MD 21231, in cooperation with all university divisions. Subscriptions are $26 per year. Deadline for calendar items, notices and classifieds (free to JHU faculty, staff and students) is noon Monday, one week prior to publication date. Phone: 443-287-9900 Fax: 443-287-9920 General e-mail: gazette@jhu.edu Classifieds e-mail: gazads@jhu.edu On the Web: gazette.jhu.edu Paid advertising, which does not represent any endorsement by the university, is handled by the Gazelle Group at 410343-3362 or gazellegrp@comcast.net.


December 19, 2011 • THE GAZETTE

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Epigenetic changes linked to inflammation-induced colon cancer B y V a n e s s a W a s ta

epigenetic abnormalities has not been clear, but in a study reported in 2008, scientists led by Baylin and research associate Heather M. O’Hagan found an important hint. Working on lab-grown cells, they created a model of DNA damage caused by severe inflammation and found that methylating enzymes known as DNA methyltransferases soon appeared on the scene, as part of the cellular DNA-repair crew. For the new study, Baylin’s team exposed cells to high levels of hydrogen peroxide, a strongly reactive molecule—known as a reactive oxygen species—which is emitted by a variety of cells during episodes of inflammation. Hydrogen peroxide can damage DNA, as well as other proteins and structures within cells. Baylin’s team, in experiments led by O’Hagan and graduate student Wei Wang, found that peroxide-induced damage recruited methyltransferases to damage sites. The enzymes also appeared to form large molecular complexes with other proteins involved in epigenetic gene silencing. These effects did not appear when DNA was damaged by gamma or ultraviolet radiation, suggesting that they are largely a result of reactive oxygen damage induced by inflammation. The team also saw rapid abnormal DNA methylation in several genes whose promoter regions contain dense groupings of cystine and guanine molecules known as CpG islands. Their epigenetic silencing also is known to contribute to cancer. Further studies with Johns Hopkins colleagues Cynthia Sears and Robert Casero showed that these protein interactions are seen in mice with a bacterially induced form of colon inflammation, a condition that accelerates the devel-

Johns Hopkins Medicine

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ohns Hopkins Kimmel Cancer Center scientists report that sharp rises in levels of reactive oxygen molecules, and the inflammation that results, trigger biochemical changes that silence genes in a pattern often seen in cancer cells. The researchers confirmed this gene-silencing effect in mice that develop inflammation-induced colon cancer. The study, reported Nov. 14 in Cancer Cell, is believed to be the first to identify a specific molecular mechanism linking inflammation to cancer epigenetics. Epigenetic changes alter the usual patterns of gene expression in cells and typically cause the silencing of tumor-suppressor genes. “Our finding could explain why epigenetic changes are found in cancer cells and one important reason inflammation is so frequently linked to cancer,” said Stephen Baylin, the Virginia and D.K. Ludwig Professor for Cancer Research in the Johns Hopkins School of Medicine and deputy director of the Johns Hopkins Kimmel Cancer Center. In the past several years, researchers have noted that cancers linked to chronic inflammation, such as some colon tumors, appear to be enabled by early changes in patterns of DNA methylation, the addition of a molecule known as a methyl group to the “engine-starter” region of a gene known as a promoter. Methylation events reduce or completely shut down the gene’s ability to make functional proteins. Cancer cells typically show abnormal patterns of DNA methylation. How inflammation brings about these

will kirk / homewoodphoto.jhu.edu

Study: Multiracial groups and social position, segregation in America

Pamela Bennett

B y A m y L u n d ay

Homewood

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he American social hierarchy places people of mixed-race ancestry below whites but above blacks, while additional social stratifications along color lines are simultaneously taking place within the nation’s multiracial groups, according to a Johns Hopkins University sociologist’s study of U.S. Census data. Pamela R. Bennett, an assistant professor in the Department of Sociology in the Krieger School of Arts and Sciences, studied the residential location of people who identified themselves with more than one racial group when filling out their 2000 and 2010 census forms. Where people live has long been associated with their social status, and the connection between neighborhoods and racial segregation is well-covered territory for demogra-

phers. Bennett took this area of study a step further to see how the connection between race, residence and socioeconomic status applies to people of multiple racial identities—such as black-white, Asian-white or American Indian–white—rather than racial minorities such as African-American, Asian or American Indian. In her research, Bennett used residential segregation as an indicator of a group’s social position and attempted to determine what the segregation of multiracial groups from both whites and racial minorities says about the social position of multiracial groups. She also wanted to find out what those patterns say about possible shifts in the nation’s racial hierarchy. She first looked at data from the 2000 census, and her findings were published in the April 2011 edition of the journal Ethnic and Racial Studies. Bennett then applied her methodology to the recently released 2010 census figures. In both cases, she found that multiracial groups occupy a social position between blacks and whites, and that the multiracial groups themselves have their own racial stratifications. Bennett found a lesser degree of segregation among people who are of both black and white heritage when compared to those whose identities are fully black. Yet the black-white multiracials appear to be more segregated than Asian-white or American Indian–white multiracials across several segregation measures. “For patterns of segregation in 2000, taking socioeconomic status into account does not change that picture,” Bennett said. “So while some scholars and activists view official recognition of multiracial identities as a movement toward the deconstruction of race, I caution against such an optimistic narrative for now.” Conclusions about the role of socioeconomic status in the 2010 patterns of segregation for multiracial groups await the release of additional census data.

opment of colon cancer in the animals. Baylin and his colleagues suspect that epigenetic silencing evolved to temporarily give inflamed tissue an opportunity to repair and renew itself. However, Baylin says, when inflammation becomes chronic and lasts too long, the silencing process may “become locked in for some vulnerable genes.” The loss of these genes may allow uncontrolled cell division and growth, bringing them one step closer to cancer, he says. Chronic inflammation induced by viruses, bacteria, toxins and autoimmune processes is well-known to promote common types of cancer, including that of the colon, lung and

liver. “Our hope is that by understanding how inflammation brings about this abnormal epigenetic process, we might be able to use drugs to target it and thereby prevent many cancers,” Baylin said. The research was supported by the National Cancer Institute, the National Institute of Environmental Health Sciences and the National Institutes of Health. Other contributors to the research were Subhojit Sen, Christina DeStefano Shields, Stella S. Lee, Yang W. Zhang, Eriko G. Clements, Yi Cai, and Hariharan Easwaran, all of Johns Hopkins; and Leander Van Neste, of MDxHealth.

Online game aims to improve scientific peer review accuracy By Tim Parsons

Bloomberg School of Public Health

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eer review of scientific research is an essential component of research publication, the awarding of grants and academic promotion. Reviewers are often anonymous. However, a new study by researchers at the Johns Hopkins Bloomberg School of Public Health found that greater cooperation between reviewer and author can improve accuracy of the review. The study is published in the Nov. 9 edition of the journal PLoS ONE. To examine the accuracy of different review processes, the Johns Hopkins researchers developed a model using an online game on the Amazon E2cloud. Participants were asked to solve and review questions from the Graduate Record Examinations. The study examined both closed

review, in which the author did not know the reviewers, and open review, where the author did know the reviewers. The study found that when review behavior was public and under open review, cooperative interactions increased 13 percent. Overall accuracy between closed and open review models was similar. However, reviewers and authors who participated in cooperative interactions had an 11 percent higher reviewing accuracy rate. “Our results suggest that increasing cooperation in the peer review process could reduce the risk of reviewing errors,” said Jeffrey Leek, lead author of the study and assistant professor in the Bloomberg School’s Department of Biostatistics. Authors of the study are Leek, Margaret A. Taub and Fernando J. Pineda. Funding for the study was provided through a Johns Hopkins Faculty Innovation Award.


4 2011 4 THE THE GAZETTE GAZETTE •• December August 15,19, 2011

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immune systems are already depressed from co-infection with HIV and who lack access to antibiotic treatments. Some 20 percent of people with the potentially deadly lung infection, caused by Mycobacterium tuberculosis, develop inflammation in other organs, including in the inner tissue linings of the eye or linings surrounding the brain. The Johns Hopkins team’s description of the animal model for ocular TB appeared in the Public Library of Science One online Dec. 5. Karakousis says that a clear and rapid test for ocular TB would not only prevent treatment delays but also reduce the rate of misdiagnosis. Suspected inflammatory disease, such as sarcoidosis and lupus in the eye, are treated with steroids, which can promote bacterial spread across other body organs, making the infection worse. Current diagnostic methods for ocular TB involve a lot of guesswork, Karakousis says. Underlying signs of active TB in the lungs, such as positive chest X-rays and sputum samples, are helpful in making a diagnosis but are often not present. Tissue biopsy of the affected part of the eye offers morereliable confirmation of infection, but the procedure involves painful needle extraction that carries the risk of permanent eye damage, even blindness. Physicians are often deciding to treat based on a high suspicion of TB infection, and then taking a “wait and see” approach for several weeks or months to determine if people are getting well or not. Karakousis and his team used small, aerosolized doses of about 200 bacteria to infect each animal’s lungs, a procedure closely replicating human TB infection, which is spread when uninfected people inhale small numbers of the organisms coughed up by people already infected. Karakousis says that all previous animal models for studying TB infection, in mice and in rabbits, used more than 10 times

larger doses of injected tubercle organisms to eventually infect the eyes, which is not really how the disease spreads to the eyes. Microscopic testing of eye tissue samples showed that all guinea pigs were infected with TB after two months, and that the disease spread through the bloodstream, as it does in humans. Moreover, small grainy nodules, a telltale sign of active TB infection, were observed in both the lungs and the inner choroid tissue layer lining the eyes. Some choroidal tissue death and thickening, as well as bleeding from blood vessels, were also seen—all known indicators of active TB infection in humans. Further tissue analysis of lung and eye granulomas revealed increased production of vascular endothelial growth factor, or VEGF, a signaling protein linked to irregular blood vessel formation and known to play a role in other vascular-related vision problems, such as blindness due to diabetes and age-related macular degeneration. Karakousis says that ophthalmologists have already had some success with VEGF antibody treatments, used in combination with standard antibiotics, to treat TB infection in the eyes and the lungs. He adds that anti-VEGF drugs could represent new therapies for ocular TB–related disease and that VEGF levels in the eye could signal active TB infection in the eye. The Johns Hopkins team next plans to test VEGF and other protein levels in eye fluid as possible diagnostic test markers for ocular TB. “Having a verifiable diagnostic test for ocular TB is key to picking up on active infections early and providing treatment that stands the best chance of preventing longterm damage, with or without any signs or

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Martin Luther King III

By Greg Rienzi

The Gazette

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artin Luther King III will be the featured guest and keynote speaker for Johns Hopkins’ 30th annual Martin Luther King Jr. birthday remem     brance, to be held at noon on Friday, Jan. 6, $51,602‐$70,883 per year     SALARY   in Turner Auditorium on the East Baltimore                   campus. 37.5 hours per week.  9:00 a.m. to 5:00 p.m.       HOURS  The eldest son of the late civil rights Worksite: Johns Hopkins University, 3400 North Charles Street  leader and Coretta Scott King was the first Baltimore, MD 21218.       keynote speaker in the series and returns for    CONTACT the milestone anniversary. Ms. Gwen Martins, Human Resources Manager,                                                             The event’s theme is “Peace, Love and The Sheridan Libraries, Johns Hopkins University, 3400 North  Dignity: King’s Ultimate Challenge.” Charles St., Baltimore, MD 21218; Email: gmartins@jhu.edu  Martin Luther King III, carrying the torch lit by both his parents, has dedicated him    self to creating and implementing strategic   nonviolent action to rid the world of social,   political and economic injustice.   King has initiated several programs to This notice is posted in connection with the filing of an Application for Alien Labor Certification  support and nurture young people, including with the U.S. Department of Labor for the job opportunity listed above.  Any person may           submit documentary evidence that has a bearing on this Labor Certification Application,         the King Summer Intern Program and A including information on available U.S. workers, wages and working conditions and/or the  Call to Manhood, an annual event designed employer's failure to meet terms and conditions set forth in the employment of any similarly  to unite young African-American males employed workers.  Such evidence should be submitted to the Certifying Officer at the U.S.  with positive adult role models. Department of Labor, Employment and Training Administration, Harris Tower,                                         In the 1980s, King was incarcerated for 233 Peachtree Street, Suite 410, Atlanta, Georgia 30303  protesting against injustices in South Africa and for the release of freedom fighter Neldegree in Library Science from an ALA‐accredited institution plus three  (3) years of experience in conducting instructional programs, working in  an academic or research library, of which one (1) year must include           working with rare books and manuscripts. 

Related websites Center for TB Research Laboratory at Johns Hopkins:

www.hopkinsmedicine.org/dom/ tb_lab Petros Karakousis:

www.hopkinsmedicine.org/DOM/ TB_Lab/faculty/Karakousis.html ‘Public Library of Science One’ article:

www.plosone.org/article/ info%3Adoi%2F10 .1371%2Fjournal.pone.0028383 like Africa and Southeast Asia, where the disease remains endemic, and to listen for clues in the patient’s life history that might alert them to earlier possible TB exposure.” TB is the leading cause of death among people co-infected with HIV, the virus that causes AIDS, and is responsible for an estimated 2 million deaths annually, including a half-million in those infected with both organisms. Seema Thayil also was a Johns Hopkins researcher involved in the study, conducted from June 2010 to June 2011. Other investigators were Thomas Albini, Andrew Moshfeghi and Jean-Marie Parel, all of the Bascom Palmer Eye Institute at the University of Miami; and Hossein Nazari and Narsing Rao, both of the Doheny Eye Institute at the University of Southern California. G

Martin Luther King III to headline Jan. 6 MLK Jr. Commemoration

NOTICE OF FILING APPLICATION FOR PERMANENT                                      EMPLOYMENT CERTIFICATION  TITLE   

symptoms of lung infection,” Karakousis said. “Until then, physicians will have to be aware to test for ocular TB, especially in regions

son Mandela. Throughout the 1990s, he addressed the moral and political dilemmas of Haiti, Nigeria, Australia and Sierra Leone. In 1998, King began his tenure as president of the Southern Christian Leadership Conference. Under his leadership, the organization convened hearings on police brutality and racial profiling in several states that led to the passage of anti–racial profiling resolutions. In 2003, he co-sponsored the 40th anniversary of the historic March on Washington with human rights organizations from across the country. In 2006, King founded Realizing the Dream, an organization that focuses on economic development, youth leadership development and nonviolence education, training and technical assistance programs. The recipient of numerous awards and several honorary degrees, he is currently president and CEO of The Martin Luther King Jr. Center in Atlanta. Begun in 1982, the Johns Hopkins Martin Luther King Jr. Commemoration honors the Nobel Peace Prize winner’s legacy of nonviolent activism and community service. The list of past speakers includes Maya Angelou, Louis Gossett Jr., Harry Belafonte Jr., the Rev. Ralph Abernathy, James Earl Jones, Jesse Jackson, Danny Glover, Rosa Parks and Coretta Scott King. The celebration will include the 21st annual Martin Luther King Jr. Community Service Awards ceremony, in which eight Johns Hopkins employees will be honored for demonstrating through community service the spirit of volunteerism and citizenship that characterized King’s life. President Ronald J. Daniels; Edward D. Miller, dean of the School of Medicine and CEO of Johns Hopkins Medicine; and Ronald R. Peterson, president of The Johns Hopkins Hospital and Health System, will give opening remarks. A decision has not yet been made as to whether the event will be simulcast to additional East Baltimore venues and other campuses, as has been the practice in the past. For updates, go to www.insidehopkinsmedicine .org.


December 19, 2011 • THE GAZETTE

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In treating third-degree burns, hydrogel helps grow new skin By Mary Spiro

Institute for NanoBioTechnology

Violence Continued from page 1 The program targets health care providers—physicians, nurses, psychologists, social workers and lay caregivers—in low-resource settings in Africa, Asia, Latin America and beyond. The free course, directed by Glass, features online video lectures, scheduled Q&A sessions, examination of case studies and discussion forums where participants, spread around the globe, can talk to each other and experts from Johns Hopkins and elsewhere. The first cohort of 50 students will begin on Jan. 13, 2012. The course has already drawn substantial inquiries from health care professionals in Ethiopia, Uganda, Kenya, Burundi, Libya, Tanzania, Kyrgyzstan and the United States. Glass expects the course to fill up quickly. The need for immediate action, she said, is great. Gender-based violence has numerous health consequences that extend beyond the immediate injury, Glass said, including maternal health, mental health issues, hypertension, cardiovascular disease and sexually transmitted infections. Studies indicate that the risk of HIV among women who have experienced violence may be up to three times higher than those who have not. Realizing this, PEPFAR, the U.S. President’s Emergency Plan for AIDS Relief, has invested close to $155 million in gender-

will kirk / homewoodphoto.jhu.edu

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ohns Hopkins researchers have developed a jellylike material and wound treatment method that in early experiments on skin damaged by severe burns appeared to regenerate healthy, scar-free tissue. In the Dec. 12–16 online Early Edition of Proceedings of the National Academy of Sciences, the researchers reported their promising results from mouse tissue tests. The new treatment has not yet been tested on human patients, but the researchers say that the procedure, which promotes the formation of new blood vessels and skin, including hair follicles, could lead to greatly improved healing for injured soldiers, home fire victims and other people with third-degree burns. The treatment involved a simple wound dressing that included a specially designed hydrogel: a water-based, three-dimensional framework of polymers. This material was developed by researchers at Johns Hopkins’ Whiting School of Engineering, working with clinicians at the Johns Hopkins Bayview Medical Center Burn Center and the School of Medicine’s Department of Pathology. Third-degree burns typically destroy the top layers of skin down to the muscle. They require complex medical care and leave behind ugly scarring. But in the journal article, the Johns Hopkins team reported that its hydrogel method yielded better results. “This treatment promoted the development of new blood vessels and the regeneration of complex layers of skin, including hair follicles and the glands that produce skin oil,” said Sharon Gerecht, an assistant professor of chemical and biomolecular engineering, who was principal investigator on the study. Gerecht said that the hydrogel could form the basis of an inexpensive burn wound treatment that works better than currently available clinical therapies, adding that the product would be easy to manufacture on a large scale. Gerecht suggested that because the hydrogel contains no drugs or biological components to make it work, the Food and Drug Administration would most likely classify it as a device. Further animal testing is planned before trials on human patients begin, but, Gerecht said, “it could

Guoming Sun, a postdoctoral fellow, and Sharon Gerecht, an assistant professor of chemical and biomolecular engineering, helped develop a hydrogel that improved burn healing in early experiments.

be approved for clinical use after just a few years of testing.” John Harmon, a professor of surgery at the Johns Hopkins School of Medicine and director of Surgical Research at Bayview, described the mouse study results as “absolutely remarkable.” “We got complete skin regeneration, which never happens in typical burn wound treatment,” he said. If the treatment succeeds in human patients, it could address a serious form of injury. Harmon, a co-author of the PNAS journal article, pointed out that 100,000 third-degree burns are treated in the U.S. every year in burn centers such as Bayview’s. A burn wound dressing using the new hydrogel could have enormous potential for use in applications beyond common burns, including treatment of diabetic patients with foot ulcers, Harmon said. Guoming Sun, a Maryland Stem Cell Research Postdoctoral Fellow in Gerecht’s lab and lead author on the paper, has been working with these hydrogels for the past three years, developing ways to improve the growth of blood vessels, a process called angiogenesis. “Our goal was to induce the growth of functional new blood vessels within the hydrogel

to treat wounds and ischemic disease, which reduces blood flow to organs like the heart,” Sun said. “These tests on burn injuries just proved its potential.” Gerecht says that the hydrogel is constructed in such a way that it allows tissue regeneration and blood vessel formation to occur very quickly. “Inflammatory cells are able to easily penetrate and degrade the hydrogel, enabling blood vessels to fill in and support wound healing and the growth of new tissue,” she said. For burns, Gerecht added, the faster this process occurs, the less there is a chance for scarring. Originally, Gerecht’s team intended to load the gel with stem cells and infuse it with growth factors to trigger and direct the tissue development. Instead, they tested the gel alone. “We were surprised to see such complete regeneration in the absence of any added biological signals,” Gerecht said. Sun added, “Complete skin regeneration is desired for various wound injuries. With further fine-tuning of these kinds of biomaterial frameworks, we may restore normal skin structures for other injuries such as skin ulcers.” Gerecht and Harmon say that they don’t fully understand how the hydrogel dressing

based violence initiatives the past two years, with millions more allocated to scaling up programs in the next three years. “We have clearly demonstrated the link between violence against women and girls to HIV,” said Glass, who also serves as an associate director of the Johns Hopkins Center for Global Health, a new program that bridges the international work of the university’s schools of Nursing, Medicine and Public Health. “And [women] are dying faster than men. Research shows that the stress of the violence relates to the further compromising of the immune system.” The root of the issue, Glass said, is that gender is not equitable in terms of power. In many places around the globe, women feel they cannot fight back, refuse their husband or partner, or insist on the use of a condom. They also fear reprisal and the stigma attached to the violence. Even when they do come forward, Glass said, victims of violence are sometimes not believed. “I’ve worked in many countries where a woman says that she was raped, but the prevailing notion is that she made it up to get someone in trouble or simply wants a service,” she said. “The problem is ignored and not addressed.” A chief goal of the Confronting GenderBased Violence course is to get health care professionals to ask the right questions. Participants will be trained to spot signs of violence, conduct screening protocols, provide care in a clinical setting and refer the individuals to appropriate ongoing physical or psychosocial support. Referral training is vital, Glass said, as in many low-resource

settings there are no shelters for women or hotlines to call, and the police have little to no influence. The key, Glass said, is to make the victims feel comfortable by stressing confidentiality. “If it’s done confidentially, they will be more willing to come forward and accept assistance,” she said. “Just asking a woman about violence is an intervention. Women often tell us that they are grateful someone has finally asked the question. They feel they are not alone, and there is someone who cares. Even women who are not abused have told us they are glad we’re asking these questions, as they know how common this issue is in their world.” Bob Bollinger, director of the Center for Clinical Global Health Education, proposed the creation of the course, knowing both the vital need and the wealth of expertise in this area at Johns Hopkins. He spotlighted the work of Glass and Jacquelyn C. Campbell, the Anna D. Wolf Professor in the School of Nursing, who has been engaged in advocacy policy work and has conducted research in the areas of family violence and health disparities related to trauma since 1980. Campbell has published more than 220 articles and seven books on violence against women and was a member of the congressionally appointed Department of Defense Task Force on Domestic Violence. She currently chairs the board of directors of the Family Violence Prevention Fund. Glass’ research centers on clinical care and intervention in the areas of violence prevention and health disparities. With funding from the National Institutes of

is working. After it is applied, the tissue progresses through the various stages of wound repair, Gerecht said. After 21 days, the gel has been harmlessly absorbed, and the tissue continues to return to the appearance of normal skin. The hydrogel is made mainly of water with dissolved dextran, a polysaccharide. “It also could be that the physical structure of the hydrogel guides the repair,” Gerecht said. Harmon speculates that the hydrogel may recruit circulating bone marrow stem cells in the bloodstream. Stem cells are special cells that can grow into practically any sort of tissue if provided with the right chemical cue. “It’s possible the gel is somehow signaling the stem cells to become new skin and blood vessels,” Harmon said. Additional co-authors of the study from the School of Medicine were Charles Steenbergen, a professor in the Department of Pathology; Karen Fox-Talbot, a senior research specialist; and physician researchers Xianjie Zhang, Raul Sebastian and Maura Reinblatt, all of the Department of Surgery and Hendrix Burn and Wound Lab. From the Whiting School’s Department of Chemical and Biomolecular Engineering, other co-authors were doctoral students Yu-I “Tom” Shen and Laura Dickinson, who is a Johns Hopkins Institute for NanoBioTechnology National Science Foundation IGERT fellow. Gerecht is an affiliated faculty member of INBT. The work was funded in part by the Maryland Stem Cell Research Fund Exploratory Grant and Postdoctoral Fellowship and the National Institutes of Health. The Johns Hopkins Technology Transfer staff has filed a provisional patent application to protect the intellectual property involved in this project.

Related websites Sharon Gerecht’s Lab:

www.jhu.edu/chembe/gerecht Johns Hopkins Burn Center:

www.hopkinsmedicine.org/burn Johns Hopkins Institute for NanoBioTechnology:

inbt.jhu.edu

Health and the Centers for Disease Control and Prevention, Glass is currently conducting four major studies on intimate partner violence. She is a past president of the Nursing Network on Violence Against Women, International. “With this course,” Bollinger said, “we are able to leverage the unique capacity of experts like Nancy and Jackie.” The Center for Clinical Global Health Education, founded in 2007 to support clinical care and research training in resourcelimited settings, complements and builds upon the extensive ongoing international, collaborative research and training programs at the schools of Medicine, Nursing and Public Health. Bollinger, a professor of infectious diseases and international health at the School of Medicine, said that an important aspect of the center’s new course is that participants will be asked to improve an existing genderbased initiative or start a new one. Johns Hopkins faculty and staff will follow up on these programs to gauge their impact. “We want to know if these programs resulted in improvements such as the prevention of violence or better treatment of victims,” he said. “We are really excited about this aspect of the program. We can see really important outcomes beyond training.” To be eligible, individuals must present a letter of sponsorship from an employer demonstrating commitment to prevention and interventions in gender-based violence through current or planned programming. G For more information on the course and the center, go to main.ccghe.net.


6 2011 6 THE THE GAZETTE GAZETTE •• December August 15,19, 2011

A chili day on the Homewood campus By Karen Clark Salinas

Work, Life and Engagement

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Tom Lewis, Michelle Carlstrom, Jerry Schnydman and Charlene Moore Hayes

Marie Chen and Saamrat Kasina

Kathleen Bruffett and Michelle Solomon

Christy Murray, Emily Calderone and Tom Calder

PHOTOS BY will kirk / homewoodphoto.jhu.edu

he competition just keeps getting hotter. This year’s Chili CookOff and Bake-Off—an annual Homewood campus fundraiser for the United Way of Central Maryland and the Johns Hopkins Neighborhood Fund—drew 11 entries in the chili category and six in the baked goods taste-off. For $5, the Dec. 5 lunchtime crowd got to sample the contenders and purchase a meal of chili, cornbread, dessert and a beverage, raising a total of nearly $900. The Johns Hopkins Federal Credit Union sponsored the chili lunch, and The Dome Corp and Johns Hopkins Real Estate donated two Baltimore Ravens tickets and a parking pass for a drawing. Prizes went to first-, second- and thirdplace winners selected by judges and to a “people’s choice” winner as voted on by the attendees. Kerstin Flynn of the Carey Business School’s Office of Campus Operations won first place for her White Chili. Second-place honors went to Samantha Ohmer of the

Krieger School’s Department of Biology for her Sweet and Spicy Chili and third place to Renato Rapada of the Krieger School’s Department of Biophysics for The Baby Maker. The people’s choice award went to Joyce Lambert of the School of Medicine for her Heartfelt Chili. Ruth Scally of Homewood Student Affairs’ Office of Student Employment Services was a double winner in the Bake-Off, with her Streusel Apple Coffeecake getting the top nod from both the judges and the crowd. Second-place honors went to Nathan Nicholes of the Whiting School’s Department of Chemical and Biomolecular Engineering for his Toll House Melt in Your Mouth Bars and third place to Charla Fowlkes of the Krieger School’s Office of Graduate Affairs and Admissions for her 5-Flavor Pound Cake. The campaign officially ended on Dec. 16. As of press time, the Homewood campus and affiliated entities had raised more than $501,491 for the United Way of Central Maryland and the Johns Hopkins Neighborhood Fund—99 percent of their $505,000 goal. The 2012 Chili Cook-Off/Bake-Off is scheduled for Nov. 9, which gives you plenty of time to perfect a winning recipe.

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December 19, 2011 • THE GAZETTE

7

E X P L O R A T I O N

NASA’s Radiation Belt Storm Probes begin space environment tests APL-built twin spacecraft will explore the sun’s influence on Earth B y G e o f f B r o wn

Applied Physics Laboratory

JHU / APL

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ASA’s Radiation Belt Storm Probes, twin spacecraft being built and tested at the Johns Hopkins University Applied Physics Laboratory, have entered a challenging series of tests designed to certify that they are ready for their August 2012 launch and two-year mission in Earth’s orbit. The coordinated measurements of the two RBSP spacecraft will advance our understanding of space weather and the sun’s influence on the Earth and near-Earth space by probing the planet’s radiation belts, which affect space weather and spacecraft operations. RBSP embarked this month on a space environment test campaign that will last into March 2012. In a controlled test facility where engineers can monitor the spacecrafts’ condition, the RBSP team is subjecting the spacecraft to physical simulations of the stresses of launch and harshness of space operations. “These are complex spacecraft, each with five very sensitive scientific instruments on board,” said Jim Stratton, mission systems engineer for RBSP at APL. “The environmental tests are designed to really subject the spacecraft and systems to realistic, challenging conditions and make sure they are ready to fly.” The first test, conducted in early Decem-

The Radiation Belt Storm Probes team at APL is shown in early December wheeling the twin satellites, stacked atop one another exactly as they will be for launch, into acoustic testing. A specialized speaker system created the same intense sounds RBSP will experience during launch and supersonic barrier breakthrough, which can reach a maximum of 134 decibels (nearly as loud as a jet engine from 100 feet away).

ber, simulated the incredibly loud noises generated during launch and the beginning of supersonic travel, when the launch vehicle passes through the sound barrier (approximately 770 miles per hour). These sounds, which can reach a maximum of 134 decibels—which can be nearly as loud as a jet engine from 100 feet away—were duplicated by a specialized speaker system that is controlled via computer to match the sonic profiles of launch and supersonic barrier breakthrough. The RBSP satellites were mated together and placed at the center of a

circular wall of powerful loudspeakers for this test, which was completed successfully. One of the substantial challenges for the probes is that they must survive launch as a single unit; later, above Earth, they will be separated and guided to their individual orbits. RBSP will next undergo a vibration test. The spacecraft are mated together again and placed on a special table that will shake them to simulate the intense physical effects of launch, and make sure the probes’ systems and electronics are secure and will operate post-launch.

In January 2012, the spacecraft will undergo an electromagnetic compatibility and interference test. This involves turning on all of the spacecrafts’ internal systems without any external power or grounding to verify there are no electronic issues, and that RBSP can successfully perform its sciencegathering mission. RBSP will enter thermal vacuum testing in February. For five weeks, the craft will endure heating and cooling cycles in a vacuum environment; during the lengthy testing, RBSP will also undergo a 10-day-long mission simulation. After that, in May, the completed RBSP spacecraft are scheduled to leave APL and travel south. “The next six months are all about continuing the tremendous efforts of the outstanding team we have assembled for this mission, and getting ready to ship the spacecraft to Florida,” says Rick Fitzgerald, program manager for RBSP at APL, referring to the Kennedy Space Center, where RBSP is scheduled for launch no earlier than Aug. 15, 2012. APL built the RBSP spacecraft for NASA and manages the mission, which is part of NASA’s Living With a Star program, guided by the Heliophysics Division of the NASA Headquarters Science Mission Directorate in Washington, D.C. The program explores fundamental processes that operate throughout the solar system, in particular those that generate hazardous space weather effects near Earth and phenomena that could affect solar system exploration. Living With a Star is managed by NASA’s Goddard Space Flight Center in Greenbelt, Md. For more about the Radiation Belt Storm Probes, and to see photos and videos of space environment testing, go to rbsp.jhuapl.edu.

JH collaborates with Lockheed Martin to build next-gen ICU Systems integration, virtual simulation to guide study of health care setting B y S h a n n o n S wi

ger

Johns Hopkins Medicine

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he Armstrong Institute for Patient Safety and Quality of Johns Hopkins Medicine is collaborating with the Lockheed Martin Corp., a global security and technology company, to create a safer and more efficient hospital intensive care unit model. The two organizations will work to streamline complex and fragmented clinical systems and processes to reduce medical errors and improve the quality of care for critically ill patients.

“A hospital ICU contains 50 to 100 pieces of electronic equipment that may not communicate [with] one another nor work together effectively,” said Peter Pronovost, Armstrong Institute director and senior vice president for patient safety and quality for Johns Hopkins Medicine. Pronovost, who often contrasts the health care and aerospace industries, said, “When [airlines need] a new plane, they don’t individually select the controls systems, seats and other components, and then try to build it themselves.” The piecemeal approach by which hospitals currently assemble ICUs, he said, is inefficient and prone to error, adding risk to an already intricate environment. “Lockheed Martin has the expertise to integrate complex systems to help us build a safer and more efficient ICU model, not just for Johns Hopkins but for patients around the world,” Pronovost said.

A single system that could prioritize patient alarms based on individual risk of cardiac or respiratory arrest, for example, could prevent “alarm fatigue,” a situation when clinicians sometimes are inundated with a chorus of competing alarms. This approach could help health care workers understand risks on a personal level based on each patient’s age, diagnosis and family history. Ray O Johnson, Lockheed Martin senior vice president and chief technology officer, said, “Flight simulators and systems integration revolutionized the aerospace industry, and similar concepts can be applied to increase effectiveness and efficiency of the health care industry. Lockheed Martin’s advanced computer-generated modeling and simulation will allow scientists to input ICU data to mimic possible outcomes of lifelike scenarios. The software can also be used to

train health care providers on newly engineered devices or processes, similar to the way pilots learn to respond to high-pressure scenarios,” he said. Johns Hopkins researchers will test alternative approaches to ICU care in a learning laboratory with a virtual simulation theater, an engineering workshop and a testing area with manikins that imitate patient conditions and responses. To further strengthen the relationship between the two organizations, Johns Hopkins has invited Lockheed Martin’s corporate director of health care innovation, Robert J. Szczerba, to serve on the advisory board of the Armstrong Institute. Szczerba will provide guidance on how advanced technologies from the aerospace and defense industries can be used to improve patient safety and overall quality of care.

Teens pick water when sugary beverage calorie count is more understandable B y N ata l i e W o o d - W r i g h t

Bloomberg School of Public Health

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hirsty? If you’re a teen, you may be more inclined to reach for plain old H2O if you knew how many calories were in sugar-sweetened beverages—this according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health. The researchers examined the effect of providing clear and visible caloric information about sugar-sweetened beverages such as soda, sport drinks, energy drinks and fruit juice at neighborhood stores, and found that providing easily understandable caloric information, specifically in the form of a physical-activity equivalent, may reduce the likelihood of sugar-sweetened beverage purchases among adolescents by as much as

half. The results are featured in a recent issue of the American Journal of Public Health. Consumption of sugar-sweetened beverages has been associated with obesity and is highest among minority and lower-income adolescents. The study was conducted at four corner stores located in low-income, predominantly black neighborhoods in Baltimore. “People generally underestimate the number of calories in the foods and beverages they consume,” said Sara Bleich, an assistant professor in the Bloomberg School’s Department of Health Policy and Management. “Providing easily understandable caloric information—particularly in the form of a physicalactivity equivalent, such as running—may reduce calorie intake from sugar-sweetened beverages and increase water consumption among low-income black adolescents.” For the intervention, one of three signs

was randomly posted with the following caloric information: “Did you know that a bottle of soda or fruit juice has about 250 calories?” (absolute caloric count), “Did you know that a bottle of soda or fruit juice has about 10 percent of your daily calories?” (percentage of total recommended daily intake) or “Did you know that working off a bottle of soda or fruit juice takes about 50 minutes of running?” (physical activity equivalent). The researchers collected data for 1,600 beverage sales—400 during a baseline period and 400 for each of the three caloric-condition interventions—sold to black adolescents, ages 12 to 18. They found that providing any caloric information significantly reduced the odds of sugar-sweetened beverage purchases by 40 percent relative to the baseline of no information. Of the three caloric-condition interventions, the physical activity equivalent was most effective, reducing the odds

of black adolescents’ purchasing a sugarsweetened beverage by 50 percent. According to the Centers for Disease Control and Prevention, more than one-third of adults and 17 percent of children in the United States are obese. Obesity increases the risk of many adverse health conditions including type 2 diabetes, coronary heart disease, stroke and high blood pressure. “Because of the inclusion of mandatory calorie labeling in the recent health reform bill, it is critical to explore the most-effective strategies for presenting caloric information to consumers on fast food restaurant menu boards,” suggest the study’s authors. The study was written by Bleich, Bradley J. Herring, Desmond D. Flagg and Tiffany L. Gary-Webb. The research was supported by grants from the Robert Wood Johnson Foundation and the National Heart, Lung and Blood Institute.


8 2011 8 THE THE GAZETTE GAZETTE •• December August 15,19, 2011 F O R

Cheers Cheers is a monthly listing of honors and awards received by faculty, staff and students plus recent appointments and promotions. Contributions must be submitted in writing and be accompanied by a phone number. BAYVIEW MEDICAL CENTER Kathleen Barnes , professor of medicine

in the Division of Allergy and Clinical Immunology, has received a four-year $9.5 million grant from the National Institutes of Health to fund her ongoing studies of asthma in populations of African descent. Barnes has achieved international prominence for her work in defining the genetic basis of asthma, especially in patients of African descent. J o s e p h C a r r e s e , associate professor of medicine and chair of Bayview’s Ethics Committee, has been selected to receive the 2011 Presidential Citation Award from the American Society for Bioethics and Humanities. The award recognizes his dedication and important work as a member of the ASBH’s Clinical Ethics Consultation Affairs Committee, which has been working to establish national standards and a certification process for health care professionals who conduct clinical ethics consultations. Jenn Nizer , longtime director of the child day care center, has been appointed chair of the Early Childhood Development Advisory Council of the Maryland State Department of Education. The council oversees every aspect of early childhood education in Maryland and has approximately 40 to 50 members who come from all sectors of the community, including the Department of Health and Mental Hygiene, fire departments, and resource and referral centers throughout Maryland. A n t o n y R o s e n , professor and chief of the Division of Rheumatology, has been awarded a nearly $1.2 million grant by Robert L. Sloan, president and CEO of Sibley Memorial Hospital and head of its Mackley Fund for research, to finance a research project titled “Precision Measurement in Rheumatoid Arthritis.” Rosen and his colleagues believe that making precise measurements of a patient’s disease and reaction to treatment is the key to determining which patients benefit most from different treatments. Roy Ziegelstein , professor and vice director of the Department of Medicine, has

T H E

received the highest honor bestowed by the American College of Physicians, selection as a master of the ACP. Ziegelstein’s many teaching awards from students and residents, his contributions to cardiology and internal medicine training, his renowned diagnostic skills and his superb clinical judgment all contributed to his selection as an ACP master. BLOOMBERG SCHOOL OF PUBLIC HEALTH Alain Labrique , assistant professor in

International Health and in Epidemiology, has been named one of the Top 11 Innovators in Mobile Health by the Rockefeller Foundation and the mHealth Alliance. The award recognizes individuals who have used mobile technology in innovative ways to improve health systems and outcomes, particularly in the most remote areas of the world. Labrique was selected for developing the mCARE program with colleagues at Johns Hopkins and in Bangladesh. The program utilizes mobile phone and database technologies to improve registration and surveillance of pregnancies and to optimize early neonatal and postpartum follow-up care in an effort to reduce maternal and neonatal mortality. Jeff Goldsmith and Russell “Taki” Shinohara are this year’s co-recipients of the Margaret Merrell Award, established in 1995 by the friends, colleagues and former students of the late faculty member. This award recognizes outstanding research by a Biostatistics doctoral student. JOHNS HOPKINS HEALTH SYSTEM Theodore Abraham , associate professor

of medicine and vice chief of the Division of Cardiology in the School of Medicine, has been appointed the first associate dean for research in the capital region. The additions to the Johns Hopkins Health System of Suburban Hospital in Bethesda, Md., Sibley Memorial Hospital in Washington, D.C., and Howard County General Hospital provide new opportunities for expanding and coordinating translational research historically based primarily at The Johns Hopkins Hospital and Johns Hopkins Bayview. Abraham’s primary responsibility will be to build research capacity at HCGH, Suburban and Sibley. THE JOHNS HOPKINS HOSPITAL Carol Iversen , program director of diag-

nostic medical sonography, has received the 2011 Most Effective Radiologic Technologist Educator Award from AuntMinnie.com,

Shealer appointed VP and general counsel of JHH and health system By Gary Stephenson

Johns Hopkins Medicine

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. Daniel Shealer Jr. has been appointed vice president and general counsel of The Johns Hopkins Health System Corp. and The Johns Hopkins Hospital. He succeeds Joanne Pollak, who in July assumed the duties of chief of staff to the Office of Johns Hopkins Medicine. Shealer served as the health system’s deputy general counsel for the past 17 years and had a pivotal role in bringing to fruition the recent affiliations with Suburban Hospital, Sibley Memorial Hospital and All Children’s Hospital, and the G. Daniel subsequent integration of those hospitals into the Johns Hopkins Health System. “Dan brings to the position a wealth of experience in corporate, legal, governance and regulatory matters. His vast experience will continue to be a tremendous value to our organization,” said Edward D. Miller,

the Frances Watt Baker, M.D., and Lenox D. Baker Jr., M.D., Dean of the Medical Faculty and CEO of Johns Hopkins Medicine. Shealer will continue to serve as the health system’s vice president for compliance, deputy general counsel for Johns Hopkins Medicine and secretary of the boards of Johns Hopkins Medicine, the health system and The Johns Hopkins Hospital. He previously held the position of senior counsel for corporate and regulatory affairs, leading oversight of business, tax and regulatory matters for the health system. Shealer currently serves on the boards of trustees of Howard County General Hospital, Mt. Washington Pediatric Hospital, Suburban Hospital Healthcare System Shealer Jr. and the Legal Aid Bureau, where he also is treasurer, and on the Mayor’s Leadership Advisory Group to End Homelessness in Baltimore City. Shealer received his bachelor’s degree cum laude in 1981 from Juniata College in Pennsylvania and his law degree from Vanderbilt University in 1984.

R E C O R D

a San Francisco–based radiology website. Iversen has worked as a full-time general sonographer at The Johns Hopkins Hospital since 1993 and was named DMS program director in 2003. JOHNS HOPKINS MEDICINE John Bergbower , a central figure in

Johns Hopkins’ security system since 2003, has been promoted to vice president for security. A 27-year veteran of the Baltimore City Police Department, Bergbower previously had served as senior director of Corporate Security, Parking and Transportation, as well as internal director of Security for the schools of Medicine, Public Health and Nursing, and as director of Investigations. He succeeds Harry Koffenberger, a three-decade veteran of law S C H O O L

O F

Ian Rosenbaum , a Preparatory faculty member, was one of 12 auditioners selected for a three-year residency with CMS Two, a program of the Chamber Music Society of Lincoln Center. The residency, designed to provide opportunities to performers in the early stages of major careers, will begin in September. David Smooke , who chairs the Conservatory’s Music Theory Department, made his New York debut as a toy pianist at the DiMenna Center for Classical Music on Dec. 3, playing a piece for amplified toy piano using extended techniques, including various types of bowing. The performance was part of Phyllis Chen’s UnCaged Toy Piano Festival. Melissa Wimbish , a Graduate Performance Diploma candidate, was one of M E D I C I N E

David Eisele named the Andelot Professor of Laryngology, Otology

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avid W. Eisele, a faculty member from 1988 to 2001 in the School of Medicine’s Department of Otolaryngology–Head and Neck Surgery, has been appointed the Andelot Professor of Laryngology and Otology and director of the department, effective March 1, 2012. He will succeed John Niparko, who has served as interim director since August 2009, when then director Lloyd Minor was named university provost. Since 2001, Eisele has been chairman of the University of California, San Francisco’s Department of Otolaryngology–Head and Neck Surgery. He also is director of the UCSF Head and Neck

enforcement, who had been head of Security since 2006. Richard Grossi , chief financial officer of Johns Hopkins Medicine since its inception, has been named by Becker’s Hospital Review as one of the “110 Hospital and Health System CFOs to Know.” Placement on the magazine’s list of top CFOs signifies that Grossi is among “the most respected and talented CFOs in the health care industry,” according to the magazine.

Cancer Program and president of the UCSF medical staff. He specializes in treating malignant and benign tumors of the head and neck, with special interest in salivary gland neoplasms and disorders. A graduate of Dartmouth College and Cornell University Medical College, he has held appointments at Johns Hopkins in Otolaryngology–Head and Neck Surgery, Oncology, and Anesthesiology and Critical Care Medicine. Niparko will remain chief of the Division of Otology, Audiology, Neurotology and Skull Base Surgery, as well as director of the Listening Center at Johns Hopkins.

appointed to the Charles Homer Haskins Chair in the Department of German and Romance Languages.

four winners of the Denver Philharmonic’s 2011–12 Young Artist Masterclass Competition for Voice and will perform Chausson’s “Chanson perpetuelle” with the orchestra on Feb. 17.

 C Street Brass , a quintet founded by Conservatory students in 2007 and mentored by faculty artist Joe Burgstaller , has been chosen as one of a select group of ensembles to be showcased at Chamber Music America’s 34th Annual Conference, to be held Jan. 12 to 15 at the Westin Times Square in New York. C Street Brass will perform a 20-minute show at the conference, at which Preparatory alumnus Aaron P. Dworkin, recently appointed to the National Council on the Arts by President Barack Obama, will be the keynote speaker.

PEABODY INSTITUTE Jennifer Nicole Campbell , a sopho-

SCHOOL OF EDUCATION Phyllis McDonald , associate professor in

KRIEGER SCHOOL OF ARTS AND SCIENCES Christopher C e l e n z a has been

more studying piano with Brian Ganz, won first prize in the Young Artist division for her composition, “Discovery,” in the Music Teachers National Association Composition Competition. She performed the work at the MTNA Delaware Winner’s Recital on Nov. 12 at the University of Delaware.
 Mark Janello , a Music Theory faculty member, presented a paper, “Unreasonably Melodious: The Grotesque and Bach’s Inverse Augmentation Canon,” in the Music of the 18th Century session at the 34th Annual Meeting of the Society for Music Theory. The meeting was held Oct. 27 to 30 in Minneapolis. P a t r i c k M e r r i l l , a junior studying piano with Yong Hi Moon, won first place in the Young Artist division of the Maryland State Music Teachers Association Competition, held Nov. 13 in Columbia, Md. John Wilson , a Master of Music candidate studying with Marian Hahn, was chosen as an alternate. A l e x a n d e r N o r r i s , a faculty artist, performs on the recently released CD Ron Carter’s Great Big Band with other notable jazz performers, including alto saxophonist Steve Wilson, a recent guest artist at Peabody.

the Division of Public Safety Leadership, has been appointed to the U.S. Department of Transportation’s Transit Rail Advisory Committee for Safety. Transportation Secretary Ray LaHood said that the committee’s recommendations will help the FTA develop new policies and practices, and, should the FTA be given authority to promulgate new transit safety requirements, the committee will write new rail safety regulations. McDonald teaches research and evaluation in the Police Executive Leadership Program. Her recent accomplishments include completing a national assessment of transit security training, helping to create curriculum guidelines for FTA training contractors and developing a strategic counter-terrorism training program for transit managers. SCHOOL OF MEDICINE Amy Bastian has been promoted to pro-

fessor of neuroscience. Jennifer Elisseeff has been promoted to professor of ophthalmology, retroactive to July 1, 2010. R i c h a r d T. J o h n s o n , professor in Neurology, received the World Federation Continued on page 9


December 19, 2011 • THE GAZETTE

Milestones The following staff members are retiring or celebrating an anniversary with the university in December 2011. The information is compiled by the Office of Work, Life and Engagement, 443-997-7000. ACADEMIC AND CULTURAL CENTERS

20 years of service Jo n es , Alice, Johns Hopkins University Press 15 years of service Wo n g , Albert, Montgomery County Campus 10 years of service Ba x ley , Philip, Center for Talented Youth

5 years of service Wym e r , Frederick, Center for Talented Youth BLOOMBERG SCHOOL OF PUBLIC HEALTH

35 years of service P rin cipe , Marilyn, Center for Alternatives to Animal Testing 30 years of service Ho b bs , Cherita, Human Resources

20 years of service Ja ck son , Rosetta, Epidemiology

15 years of service Ha mann , Ray, Advanced Technology Services Jo h n g , Surita, Information Systems 10 years of service Do n aldson , Victoria, Center for American Indian Health Gelle r , Stephanie, Finance Getac he w , Senayt, Disease Prevention and Control Heminthavong , Amanyphone, Gates Institute 5 years of service Bh a gat , Surama, Center for Communication Programs Bla n chard , Jayne, Center for Adolescent Health

Cheers Continued from page 8 of Neurology Medal for Scientific Achievement in Neurology at the World Congress of Neurology on Nov. 14 in Marrakesh, Morocco. Xingde Li has been promoted to professor of biomedical engineering. Alicia Neu has been promoted to professor of pediatrics. Nicole Parrish , assistant professor of pathology and director of Medical Mycobacteriology, has received certification as a diplomate of the American Board of Medical Microbiology. ABMM certification is the highest credential that a doctoral-level clinical microbiologist can earn. David Pearse has been promoted to professor of medicine. Paul J. Scheel Jr. has been named first holder of the Ronald R. Peterson Professorship in the Department of Medicine, effective Jan. 1, 2012. L i l l i e S h o c k n e y , University Distinguished Service Assistant Professor of Breast Cancer, administrative director of the Johns Hopkins Avon Breast Center at JHH and also a guest lecturer and distinguished speaker at the School of Nursing, was selected as this

HOMEWOOD STUDENT AFFAIRS

10 years of service H e l m u th , Barbara, Homewood Student Affairs KRIEGER SCHOOL OF ARTS AND SCIENCES

20 years of service Zhe ng , Wei, Physics and Astronomy 10 years of service F oste r , Sara, Office of the Dean SAIS

10 years of service B u rrow es , Janet, Career Services SCHOOL OF EDUCATION

10 years of service Wood , Maxine, Center for Social Organization of Schools SCHOOL OF MEDICINE

Retirees Mi l l a r , Mary, 12 years of service, Ophthalmology P roc tor , Rebecca, 23 years of service, Pediatrics S i m m ons , Carol, 26 years of service, Chairman’s Office of General Administration 40 years of service P a ste r f i el d , Emily, Institute of Genetic Medicine S a nde rs , Paulette, Institute of Genetic Medicine 30 years of service E l k , Andrea, Gynecology and Obstetrics

25 years of service Ge rc za k , Charlotte, Pulmonary/Critical Care Le a the rm a n , Kellie, Radiology Tu rne r , Linda, Neurology 20 years of service Mc Cu m b er , Karen, Facilities S hi rk , Karen, Otolaryngology 15 years of service B a i l e y , Bethany, Ophthalmology B u rke , Robert, Ophthalmology D ol a n , Joanne, Fund for Johns Hopkins Medicine Low e r y , John, Clinical Practice Association Wood a rd L u a l l en , Pamela, Clinical Practice Association

year’s Amazing Nurse in a national contest to celebrate and reward nurses’ value, sponsored by the Johnson & Johnson Campaign for Nursing’s Future. Shockney’s work with breast cancer patients was recognized during the 2011 CNN Heroes: An All-Star Tribute show, held Dec. 11 in Los Angeles. Artin A. Shoukas is to be appointed professor emeritus in the departments of Biomedical Engineering, Physiology, and Anesthesiology and Critical Care Medicine, effective Feb. 29, 2012. Martha Tesfalul , a member of the Class of 2013, has received an Association of American Medical Colleges Herbert W. Nickens Award, given to individuals who have made outstanding contributions to promoting justice in medical education and health care equities for Americans. The award includes a $5,000 scholarship. As an entering medical student in 2010, Tesfalul, the daughter of Eritrean immigrants and an aspiring pediatrician whose ambition is to work in medically underserved communities, was one of only three students selected to receive a $40,000 annual Johns Hopkins Medicine Scholarship, designed to increase diversity in the School of Medicine. Mark Young , part-time assistant professor of physical medicine and rehabilitation, has received the International Society of Physical and Rehabilitative Medicine’s Hairm Ring PM&R International Memorial

10 years of service A b r a m u k , Sharon, Neurosurgery C u r r y , Kelley, Ophthalmology Da n n en f el s er , Linda, Gynecology and Obstetrics F o r d , Nancy, Surgery Ha m m a n n , Lisa, Fund for Johns Hopkins Medicine Pen n a t h u r , Veena, Otolaryngology Pu m p h r ey , Niki, Ophthalmology R o s m a n , Lori, Welch Medical Library Sa u t er , Mary, Gynecology and Obstetrics Wa h l i n , Tamara, Radiology Wa t s o n , Remel, Radiology Ya n g , Shirley, Radiology 5 years of service B ea l e , Erica, Urology B en t k o w s k i , Michelle, Surgery B r o w n , Kristen, Anesthesiology and Critical Care E n n el s , Trarenda, Ophthalmology E s p i n o z a , Lisbeth, General Internal Medicine F r o s t , Keisha, Human Subjects Research F u l t o n , Juanita, Urology Ha y , Nadia-Lynn, Infectious Diseases Hu f f i n es , Scott, Anesthesiology and Critical Care Hu s s a i n , Sainjali, Orthopaedics In g r o d i , Shanna, Ophthalmology Kel l y , Lorraine, Pediatrics L u ck et t , Patrice, Clinical Practice Association M o r g a n , James, Pathology M o r r i s o n , Akeeta, University Health Service O j ed a , Jessica, Infectious Diseases Po l l a r d , Kai, Oncology Pu r d y , Elizabeth, Clinical Pharmacology R o g a l s k i , Vincent, Neurology Sci u t o , Angela, Neurosurgery Sep u l v ed a , Kristin, Anesthesiology and Critical Care St a i cu , Elena, Infectious Diseases T h o r n t o n , Kim, Welch Medical Library Ts em a ch , Michal, University Health Service Wi s n i ew s k i , Timothy, Medical Archives

9

25 years of service Rober t s , Ellsworth, Sheridan Libraries 10 years of service Kaned a , Ben, Sheridan Libraries UNIVERSITY ADMINISTRATION

45 years of service Sund er l and , Joyce, Office of the Chief Networking Officer 25 years of service Cat hc ar t , Carla, Office of the Secretary to the Board of Trustees 20 years of service H i nnenkam p , Stephen, Controller

15 years of service D i ber ar d i no , Tracy, Controller Gal e , Nadine, Facilities M i l l s , Deborah, Benefits Administration and Shared Services 10 years of service M i l l er , James, Jr., Facilities Rei ner , Salem, Community Affairs Z vag el s ky , Irene, Enterprise

Applications 5 years of service Ad es , Emily, Creative Services Boy d , Leeanne, Benefits Administration

and Shared Services Car l s t r om , Michelle, FASAP/

Work, Life and Engagement D es i r , Nadia, Animal Care and Use Committee Gam ber , Joseph, Controller H i c km an , Andre, Office of the Chief, Enterprise Technology Services H oop er , Laura, Johns Hopkins Internal Audits Wel c h , Louise, Johns Hopkins Internal Audits WHITING SCHOOL OF ENGINEERING

Retiree L eonar d , Natalie, 26 years of service,

Faculty Affairs

10 years of service D avi s , Paula, Materials Science and

Engineering H i c key , Mary-Joe, Finance and

SHERIDAN LIBRARIES/JHU MUSEUMS

Administration

30 years of service G i l l i s p i e , James, Sheridan Libraries

H i g g i ns , Deborah, Information Security

Award for his contributions to advancing the cause of international education and humanitarian exchange in physiatry.

Department of Community Public Health, received the 2011 Consortium of Universities for Global Health Early Career Award in recognition of her dedication to critical global issues and remarkable record of achievement. The distinction includes a $1,000 financial award and plaque, which was presented Nov. 13 at the annual CUGH Global Health Conference in Montreal. Ellen Ray , instructor in the Department of Community Public Health, was selected to participate in the Quality and Safety Education in Nursing Education Consortium Institute, funded by the Robert Wood Johnson Foundation and held Sept. 14 to 16 in Seattle. The program taught quality and safety content, as well as innovative techniques for teaching the content to students and other faculty. Areas covered included patient-centered care, teamwork and collaboration, evidence-based practice, quality improvement, patient safety and informatics.

SCHOOL OF NURSING Patricia Abbott , assistant professor in

Health Systems and Outcomes, was invited by William E. Kennard, U.S. ambassador to the European Union, to the High-Level Workshop on Innovation in Healthcare, held Nov. 16 in Brussels. The workshop was attended by policymakers and academic and private sector representatives from both sides of the Atlantic in order to produce a set of policy recommendations on health care and remote monitoring for cure and prevention. The recommendations will be shared with relevant transatlantic policymakers to ensure rapid uptake of health technology for the benefit of patients around the world. Barbara Badman , a student in the traditional Class of 2013, won first place for her research poster, “Investigating the Genotypic Distribution of High-Risk Human Papillomavirus Among Women in Northern Tanzania in an Effort to Determine Efficacy,” submitted as part of the Johns Hopkins Vaccine Initiative at the Bloomberg School of Public Health. Badman is the first non–Bloomberg School student to win first place. Nancy Glass , associate professor in the

Institute

WHITING SCHOOL OF ENGINEERING Jerr y Prince , the William B. Kouwen-

hoven Professor of Electrical and Computer Engineering, has been elected a fellow of the Medical Image Computing and ComputerAided Intervention Society in recognition of his “significant contributions for medical imaging and analysis.” The society elects only three fellows each year.


10 2011 10 THE THE GAZETTE GAZETTE •• December August 15,19, 2011 H U M A N

R E S O U R C E S

B U L L E T I N

B O A R D

Notices

Hot Jobs

No notices were submitted for publication this week.

Listed below are some of the university’s newest openings for indemand jobs that we most urgently need to fill. In addition to considering these opportunities, candidates are invited to search a complete listing of openings and apply for positions online at jobs.jhu.edu.

Homewood Office of Human Resources Wyman Park Building, Suite W600 410-516-7196 The senior enterprise resource planning business analyst is responsible for the day-to-day activities and tasks assigned to the support of SAP modules and master data elements, and interfaces with external systems. Among the duties are the technical maintenance of the application, including system configuration and coordination with developers for custom program maintenance, and participating in the maintenance support team response to enterprisewide customer requests for complex problem resolution. For a more detailed job description and to apply, go to jobs.jhu.edu. 49218 49220 49221 49223

Senior ERP Business Analyst Senior ERP Business Analyst Senior ERP Business Analyst Senior ERP Business Analyst

School of Medicine Office of Human Resources 98 N. Broadway, Suite 300 410-955-2990 The Armstrong Institute for Patient Safety and Quality is seeking qualified applicants to serve in the position of Quality and Innovation Project Administrator, who will help organize the successful completion of patient safety and quality improvement projects throughout Johns Hopkins Medicine. In that role, the administrator will serve as a direct resource with technical expertise for improvement teams on methods, practice and framework of improvement projects. For a detailed job description and to apply, go to jobs.jhu.edu. 49936

Quality and Innovation Project Administrator

Schools of Public Health and Nursing Office of Human Resources 2021 E. Monument St. 410-955-3006 The Bloomberg School of Public Health is seeking skilled applicants for part- and full-time positions. For detailed job descriptions and to apply, go to jobs.jhu.edu. 48603 48892 49529 49767 50426 50466 50525 50615 50719 50774 50775

Senior Biostatistician Research Program Manager Senior Research Data Analyst Programmer Analyst Administrative Coordinator Student Affairs Officer Nurse Practitioner/Physician Assistant Senior Research Nurse Community Relations Manager Senior Research Program Coordinator II Statistical Analyst

Johns Hopkins University is an equal opportunity employer and does not discriminate on the basis of gender, marital status, pregnancy, race, color, ethnicity, national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, other legally protected characteristics or any other occupationally irrelevant criteria.

Woodcliffe Manor Apartments

S PA C I O U S

G A R D E N A PA RT M E N T L I V I N G I N

R O L A N D PA R K

• Large airy rooms • Hardwood Floors • Private balcony or terrace • Beautiful garden setting • Private parking available • University Parkway at West 39th St. 2 & 3 bedroom apartments located in a private park setting. Adjacent to Johns Hopkins University Homewood Campus and minutes from downtown Baltimore.

410-243-1216

105 West 39th St. • Baltimore, MD 21210 Managed by The Broadview at Roland Park BroadviewApartments.com

IPS Continued from page 1 The Johns Hopkins students conducted the work during the fall 2011 semester and presented their findings Dec. 13 to city officials and neighborhood association leaders who had been invited to the Homewood campus. IPS will publish the final study this spring. The students were given a hypothetical charge from Baltimore Mayor Stephanie Rawlings-Blake to study how ethnic and racial change varied across a sampling of diverse neighborhoods, building off the results of the 2010 census. The project covered 38 census tracts in five main study areas: the northwest, the north central, the northeast, the “gold coast” and the southern peninsula. Specifically, the students were asked to look at the ethnic and racial profiles of neighborhoods, determine whether ethnic and racial groups are concentrated in geographic enclaves within neighborhoods, gauge the stability of the city’s ethnically and racially diverse neighborhoods, and study the relationship between ethnic and racial change and such factors as median house sale prices, education attainment, median income and crime. “Race is an essential part of Baltimore’s story,” said Sandra Newman, a professor in the Institute for Policy Studies, who teaches the annual course. “With the significant increase in ethnic diversity occurring throughout the United States during the last decade, we were intrigued by the prospect that our traditionally black and white city was also becoming more ethnically diverse, and all that might imply, such as integration among ethnically diverse residents both geographically and socially, and whether Hispanics and Asians are acting as ‘buffers’ between blacks and whites.” The students found that for every rule there was an exception, and common threads were tricky to come by. While Baltimore has lost more than 20 percent of its population since 1980, nearly half the neighborhoods examined have increased in population size, notably Fells Point, Belair-Edison, Cross Country, Cheswolde, Coldspring, Falstaff, Sharp-Leadenhall, Otterbein, Loyola/Notre Dame and Roland Park. In many cases, neighborhoods experienced a sharp decrease in white residents mirrored by an increase in black residents. In 1980, 54 percent of Baltimore neighborhoods were predominantly white; in 2000, that number was 28 percent. Five neighborhoods, however, had notably different patterns. Upper Fells Point experienced a sizable increase in the proportion of Hispanic residents. Tuscany-Canterbury and Roland Park, areas located near the university’s Homewood campus, experienced a marked increase in Asian residents. In Otterbein, the population had a net rise of 113 percent, from fewer than 2,000 residents in 1980 to more than 4,000 in 2010, 76 percent of whom were white. The increase was largely attributed to the success of the “dollar homes” urban homesteading program initiated in the 1970s. The neighborhoods of Sharp-Leadenhall and Cheswolde also had net increases, but in their cases both black and white residents were moving in.

Newman said that Cheswolde was a very interesting case. Cheswolde, a northwest neighborhood located between Mount Washington and Fallstaff, has had a very stable ethnic and racial profile over the past three decades, roughly 70 percent white and 30 percent black, with no clear evidence of spatially segregated racial enclaves. “A provocative thought is that Cheswolde may demonstrate that class matters more than race, though this is admittedly sheer speculation,” Newman said. Although ethnic and racial change is often associated with decline in markers of neighborhood quality, such as median home sales price and education attainment, once again there were many exceptions, such as the areas of Coldspring, Northern Frankford, Cedmont, Loyola/Notre Dame and Cross Country. In last week’s presentation, the students told the audience that neighborhoods such as Cheswolde demanded further study to determine the factors that have led to the community’s stability and population increase. “The next step is to look at these exceptions and find out what is happening. There are likely lessons to be learned here,” said Bonnie O’Keefe, who focused on the Otterbein neighborhood. To conduct the study, the students reviewed existing literature and then examined quantitative data including census statistics from 1980 to 2010, the American Community Survey and administrative data, including crime statistics and home sale prices. The students, who worked in five large groups, also interviewed residents and conducted media analyses and onsite observations of the neighborhoods. O’Keefe, a New York native who is new to the area, said that the project exposed her to many parts of the city she now calls home. “I learned a lot about the history of Baltimore and its neighborhoods,” O’Keefe said. “I explored areas I likely wouldn’t have seen if not for the project guiding me through it.” Whitney Moyer said that the project was detailed and intensive, requiring many technologies and strategies. “We learned many material skills that we can apply to different types of research projects and studies,” said Moyer, a native of York, Pa. “Very few of us had been involved in a study of this scale before.” Each year, the semester-long study of Baltimore gives Newman’s students a strong foundation on which to build careers as public policy analysts. During the term, the students work on different analyses, including this one that focuses on a public policy problem and aims to help find a solution. Newman said the information the students gathered could prove useful to city officials, specifically Mayor Stephanie Rawlings-Blake, who has stated an ambition to add 10,000 families to the city over the next decade. “We’ve already achieved the goal of disseminating the study to city leaders, community organizations and neighborhood residents and beginning a discussion of ethnic and racial diversity in Baltimore,” Newman said. “I’ve received about a dozen emails since Tuesday’s presentation with follow-up questions, and a few community organizations have asked students to attend meetings and discuss the data and their implications.” G

Need extra copies of ‘The Gazette’? A limited number of extra copies of The Gazette are available each week in the Office of Communications, Suite 540, 901 South Bond St., in Fells Point. Those who know they will need a large number of newspapers are asked to order them at least a week in advance of publication by calling 443-287-9900.


December 19, 2011 • THE GAZETTE

Classifieds APARTMENTS/HOUSES FOR RENT

Ashland/Hunt Valley/Cockeysville, 4BR, 3.5BA TH, AC, front loader W/D, 2 fps, hot tub, fenced patio w/storage, walk to NCR trail, avail Jan 1. $1,975/mo. 410790-6903. Bolton Hill, 1BR apt sublet, free prkng and laundry, 15-min walk to Penn Station, nr light rail/metro. $800/mo incl heat, water, Internet. qhgb253@gmail.com. Brewers Hill, rehabbed 2BR, 2.5BA TH, gourmet kitchen, fin’d bsmt, no pets, avail Feb 1. $1,850/mo. 410-303-1214 or hudsonstreetrental@hotmail.com. Butchers Hill/Upper Fells Point, 1BR, 1BA apt, 2 flrs, kitchen, new W/D, bsmt storage, lg backyd, walk to school. $895/mo + utils. Sharon, 443-695-9073. Canton, 2BR, 2BA waterfront condo, W/D, 2 garage prkng spaces, avail Feb 2012, pics avail. $3,000/mo + utils. cpruva@yahoo .com. Deep Creek Lake/Wisp, cozy 2BR cabin w/ full kitchen, call for wkly/wknd rentals. 410638-9417 or jzpics@yahoo.com (for pics). Ellicott City, spacious 3BR, 2.5BA TH on corner, new windows, kitchen/dining area, fin’d walkout bsmt, deck/patio, Centennial high school zone. $1,875/mo. 410-979-9065 or rashmachaudhry@yahoo.com. Gardenville, lg studio bsmt apt, open flr plan, W/D on same level, nr JHH/JHU/Bayview. $675/mo + utils + sec dep. 410-426-8045 or rent5214anthony@verizon.net (for pics). Homeland, renov’d 2BR, 2BA in quiet bldg, new kitchen, dw, gas stove, CAC, W/D and storage in bsmt, balcony w/stream view, nr Belvedere shops, gated community has pool and exercise rm. $1,225/mo incl heat, prkng. 410-243-0007 or tinyurl.com/ c46vd4q (for pics). Homeland, 1BR, 1BA duplex on 26-acre estate, living rm, dining rm, kitchen, hdwd flrs, W/D, dw, prkng, pref mature prof’l. $975/mo incl utils. abbottja@hotmail.com. Lutherville-Timonium, quiet, beautiful 3BR, 3BA house, hdwd flrs, well-designed kitchen, living rm, bsmt and family rm, garage, no pets/no smokers, 15-25 mins to Homewood or JHMI, avail Feb 1. $1,850/ mo + utils. Sheng, 443-690-1483 or sheng.w.wu@gmail.com. Pikesville, recently renov’d 4BR, 1BA house, hdwd flrs, deck, porch, fenced yd, walking distance to subway. $1,200/mo. 410-370-2822 or lenabe52@gmail.com. Roland Park, lg 1BR apt + dining rm, avail Dec 15. $1,100/mo incl heat, garage space, storage unit. mikesuse@comcast.net. 2907 St Paul St, newly renov’d 1BR apt, 1st flr, hdwd flrs, new cabinets, safe and quiet neighborhood. $900/mo incl heat, water. murilo_silvia@hotmail.com.

HOUSES FOR SALE

M A R K E T P L A C E

smoker, move in Feb 1 (flexible), 10-min walk to JHU. $600/mo + utils. angiemelliott@ gmail.com.

CARS FOR SALE

hdwd flrs throughout, new windows, new kitchen, new W/D, move-in ready and affordable. $149,900. 443-851-6514 or panfile@gmail.com.

’89 Chevy Silverado pickup, 4x4, rebuilt motor, new tires. $2,000. John, 443-7507750.

Fells Point (300 blk S Durham St), 3 stories, new front and rear masonry work, nice yd, 3 blks to JHH. $175,000. Dorothy, 410-4193902.

’05 Lexus SC430, black w/off-white leather interior, Navi, CD/cassette, garage-kept, clean, well maintained w/all records, 90K mi. $21,000/best offer. Monica, 410-3714318.

Lutherville, 5BR, 2.5BA single-family splitlevel, on 0.42 acre lot, 2,498 sq ft, fp, hdwd flrs, orig owner, great public school district, nice neighborhood, good for kids, conv location. Tony, 410-804-3653.

’07 VW Passat, black, leather, DVD, Navi, CD, MP3, clean, up-to-date on maintenance, 115K mi (highway). $9,500. 804504-1202 or louis.alexjr@gmail.com.

Manhattan-style efficiency condo in owneroccupied, elegant and secure bldg, steps from Homewood campus. $98,500. 443414-6282. Naples, FL, 2BR, 2BA condo in private 55+ community w/clubhouse and swimming pool, 26-ft dock, no bridges to Gulf, heated pool. $249,000. sticks@maine.edu. Washington Hill, 3BR, 2BA condo w/ contemporary layout, walk to JHH/shuttle, move-in ready. 717-739-8233. I-83/Timonium exit, 4BR, single-family house, 5 fin’d levels, remodeled BAs, fp in living rm, new roof/windows, hdwd flrs. $399,000. Val, 443-994-8938 or yankybrit@ hotmail.com.

ROOMMATES WANTED

F nonsmoker wanted to share 2BR apt (218 N Charles St) in downtown Baltimore, conv to bus stops, 1BR, 1BA avail. $765/mo incl heat, water (elec and Internet separately assessed, usually less than $50). 703-9664295. Nonsmoker wanted for furn’d 700 sq ft BR in 3BR house in Cedonia owned by young F prof’l, bright, modern kitchen w/convection oven, walk-in closet, landscaped yd, lg deck, free prkng, public transportation to JHU, wireless Internet incl’d. $550/mo + utils. 410-493-2435 or aprede1@yahoo.com. Washington Hill, nonsmoker bedspacer in contemporary condo, adjacent to Church Professional Bldg (98 N Broadway), walk to JHH/shuttle. $450/mo + utils. retzcare@ yahoo.com.

ITEMS FOR SALE

Conn alto saxophone, in excel cond. 410488-1886. La-Z-Boy sofa and loveseat set, very comfortable, in very good cond, cushions incl’d, treated w/stain-resistant spray when new. $250. ar_thakar@yahoo.com. Single ticket for Center Stage’s production of GLEAM, based on Zora Neale Hurston’s Their Eyes Were Watching God, 8pm on Fri, Jan 13, row K, seat 19. $40. Lori, 410-9177774 or niccole532@comcast.net. Sand beach chairs (2), inkjet printer, oilfilled heaters (3) and baseboard heaters (2), portable canvas chair, keyboard case, 100W amplifier. 410-455-5858 or iricse .its@verizon.net. Motorcycle gear: Women’s leather jacket, lined, XS, $125; women’s Milwaukee boots, #7, $85; 12-volt battery charger, $45; all in excel cond. lisamwolf@comcast.net. Classical guitar, 1977 Calidad Suprema by Jose Oribe, beautifully crafted, warm sound, good projection, in excel cond, incls orig case. $7,500/best offer. 443-621-5650. Bassett pecan wood dining rm table w/pad, leaf and 6 chairs, $200; Bassett pecan wood hutch, 2 glass doors, 3 cabinets on bottom, $200; both in good cond, best offers accepted. 443-417-3817 or vainmd23@aol.com. Bookcases (5), coffee tables (2), kitchen table w/chairs, dresser, misc housewares. wallrat@gmail.com.

Share all new refurbished TH w/medical students, 4BRs, 2 full BAs, CAC, W/D, dw, w/w crpt, 1-min walk to JHMI, 924 N Broadway. gretrieval@aol.com.

Classified listings are a free service for current, full-time Hopkins faculty, staff and students only. Ads should adhere to these general guidelines:

Rm in updated single house in nice, safe Towson area, free prkng, 2-min walk to MTA #3, 19 and 55, 20-min drive to Homewood campus or JHMI. $580/mo + utils. wjfj@hotmail.com.

• One ad per person per week. A new request must be submitted for each issue. • Ads are limited to 20 words, including phone, fax and e-mail.

F nonsmoker wanted for 1BR in 2BR W University Pkwy apt, share w/Hopkins alumna, AC, heat, hot water, 5 mins to campus, no pets, start January. $540/mo + 1/2 elec. gwxts5@gmail.com.

Share Charles Village apt w/JHU grad student, hdwd flrs, living rm, CAC/heat, your rm has a desk and chair, 2 lg windows and HICKORY HEIGHTS WYMAN COURT a patio, nr #3 bus stop, nr BMA/sculp Just Renovated! A lovely hilltop setting on Hickory Avenue Beech Ave. adj. to JHU! ture garden/Homewood campus, would like in Hampden! Studios - $595 - $630 someone to stay 6 mos. $430/mo + sec dep 2 BD units from $760 1 BD Apts. - $710-740 (1 month’s rent). 646-344-0831. 2 BD from $795 w/Balcony - $790!

Rm avail in Hampden, share house w/33-yrold F, shared BA, W/D, hdwd flrs, pref non-

Apple iBooks (several), G3 or G4, 12" to 14", wireless, OSX 10.4, in very good shape. $120 and up (negotiable). hopkinsbob@ yahoo.com (for pics/details).

SERVICES/ITEMS OFFERED OR WANTED

Transmission repairs, rebuilt or used, 20% discount for all JHU faculty, staff, students and employees, free estimate, 8am-10pm. Bob, 410-574-8820. Mt Washington family needs nurturing, enthusiastic, creative, active person to care for 2-mo-old daughter, starting January when mother returns to work, pref experience w/infants, nonsmoker, OK w/pets, own transportation a must. hvahvet@gmail.com. Schedule fun at your holiday parties w/ intuitive psychic Catori and astrologer/tarot card reader Eliza. Eliza, 410-967-3112. Classical guitarist will play at your event or holiday party; plays other types of music also. 443-801-7592. Free jewelry: look at quality jewelry, receive percentage of sales, invite friends from home or office. 646-441-1534. Friday Night Swing Dance Club, open to public, great bands, no partners necessary. 410-663-0010 or www.fridaynightswing.com. Tutor for all subjects/levels; remedial and gifted; help w/college counseling, speech and essay writing, editing, proofreading. 410-337-9877 (after 8pm) or i1__@ hotmail.com. Searching for donations of video and computer games and Nintendo DS machines for pediatric psychiatric unit. Nurse Annie, 716-430-2768. Holiday auto detailing, email your requests. rquinlan2010@hotmail.com. Piano lessons by Peabody graduate student, reasonable rates. 425-890-1327. Hauling/junk removal, next-day service, free phone estimate, 15% discount for all Hopkins. John, 443-682-4875. Licensed landscaper avail for trash hauling, fall/winter leaf or snow removal. Taylor Landscaping LLC. 410-812-6090 or romilacapers@comcast.net. Need help writing letters? Experienced writer will write/edit all types of letters to your specifications. emceea@gmail.com.

PLACING ADS

Share apt on W University Pkwy, across from Homewood Field, beginning spring 2012, name a reasonable price. amaechipa@ hotmail.com.

Catonsville, fully renov’d 3BR, 2BA RH,

Shown by appointment 410.764.7776 www.BrooksManagementCompany.com

11

• We cannot use Johns Hopkins business phone numbers or e-mail addresses. • Submissions will be condensed at the editor’s discretion. • Deadline is at noon Monday, one week prior to the edition in which the ad is to be run. • Real estate listings may be offered only by a Hopkins-affiliated seller not by Realtors or Agents.

(Boxed ads in this section are paid advertisements.) Classified ads may be faxed to 443-287-9920; e-mailed in the body of a message (no attachments) to gazads@jhu.edu; or mailed to Gazette Classifieds, Suite 540, 901 S. Bond St., Baltimore, MD 21231. To purchase a boxed display ad, contact the Gazelle Group at 410-343-3362.

The JHU Weather Emergency Line The fastest and most accurate source for Johns Hopkins weather emergency information at the university is the weather emergency phone line. Call 410-516-7781 or, from areas where Baltimore is a long-distance call, 800-548-9004. The same information is also posted online at webapps.jhu.edu/ emergencynotices. The hospital’s weather emergency policy is also online, at www .insidehopkinsmedicine.org/operations_integration/OPS/weather.cfm.


12 THE GAZETTE • December 19, 2011 K U D O S

Nobelist Adam Riess gets the star treatment in Sweden By Lisa De Nike

Homewood

T

FRIDA WESTHOLM / ©THE NOBEL FOUNDATION

wo months after being named a recipient of the 2011 Nobel Prize in physics, Adam Riess accepted his Nobel medal from the Royal Swedish Academy of Sciences during a ceremony in Stockholm on Saturday, Dec. 10. During their time in Stockholm, Riess and his fellow laureates were treated as celebrities. In addition to receiving their Nobel medals directly from the King of Sweden, they spent the week of Nobel-related activities in true star style, being driven around in Volvo limousines, being toasted at champagne receptions, dining at the lavish Nobel banquet hosted at Stockholm City Hall (where Riess was seated next to the Crown Princess of Sweden) and even giving autographs and posing for photos for the clusters of star-struck Swedes who typically gather outside the official Nobel events. “This week has been magical, sort of like scientists’ fantasy camp,” Riess said from Stockholm. “I look forward to sharing the glow of this event with those in Baltimore when I return.” Riess was recognized by the Royal Swedish Academy for his leadership in the High-z Team’s 1998 discovery that the expansion rate

Adam Riess acknowledges the crowd’s applause after receiving the 2011 Nobel Prize in physics from Sweden’s King Carl XVI Gustaf during a ceremony held Dec. 10 in Stockholm.

of the universe is accelerating, a phenomenon widely attributed to a mysterious, unexplained “dark energy” filling the universe. Riess, a Krieger-Eisenhower Professor at Johns Hopkins and a research scientist at the Space Telescope Science Institute, shares this year’s prize with High-z teammate Brian Schmidt, of the Australian National D E C .

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University, and Saul Perlmutter, an astrophysicist at the University of California, Berkeley and the Lawrence Berkeley Laboratory, whose Supernova Cosmology Project team published similar results shortly after those published by Riess and Schmidt. In addition to medals and diplomas received at the ceremony, the two teams –

J A N .

Calendar

Montgomery County Campus.

noon.

B L OO D D R I V E S

Thurs., Dec. 29, 9 a.m. to 3 p.m. JHU/American Red Cross

Blood Drive. For more information, call 410-614-0913 or email johnshopkinsblooddrive@jhmi .edu. Turner Concourse. EB

Mon., Jan. 9, 6:30 to 8 p.m.

100 International Drive.

L E C T URE S

Dean’s Lecture I—“Quality Control During Protein Synthesis” by Rachel Green, SoM. Hurd Hall. EB

Mon., Jan. 9, 4 p.m.

COLLOQUIA

“Weathering the Storm: Patents in the Cloud,” an Applied Physics Laboratory colloquium with patent attorney Richard Gilly. Parsons Auditorium. APL Fri., Jan. 6, 2 p.m.

I N FOR M A T I O N SESSIONS Carey Business School graduate programs information sessions.

For information or to register, go to carey.jhu.edu/admissions/ admissions_events/pt_events .html. •

Sat., Jan. 7, 10:30 a.m. to

S E M I N AR S

Tues., Jan. 3, noon. “Controlling Stochastic Gene Expression in the Drosophila Retina,” a Biological Chemistry faculty candidate seminar with Robert Johnston Jr., New York University. Mountcastle Auditorium. EB

“Maternal Iodine Deficiency During Pregnancy and Child Cognition, Motor Skills and Growth at Age Five Years in Rural Bangladesh,” an International Health thesis defense seminar with Hua Jing. W2030 SPH. EB

Tu e s . , J a n . 3 , 2 p . m .

“How and Where Transposons Go,” a Carnegie Institution Embryology seminar with Nancy Craig, SoM. Rose Auditorium, 3520 San Martin Drive. HW

Mon., Dec. 19, 12:15 p.m.

Dec. 21, noon. “Ion Channels in the Lysosome: Opening the Gate to the Cell’s Recycling Center,” a Physiology seminar with Haoxing Xu, University of Michigan. 203 Physiology. EB

Wed.,

Wed., Dec. 21, 4 p.m.

ing Color: Uncovering the Molecular Secrets of Compartmentalized PKA and AMPK Signaling,” a Pharmacology and Molecular Sciences thesis defense seminar with Vedangi Sample. 303 WBSB. EB

“In Liv-

“Monitoring Targeted Cancer Therapy With Targeted Molecular Diagnostics: The CML BCR-ABL Paradigm,” a Molecular Pathology seminar with Richard Press, Oregon Health and Science Uni-

share a cash award of $1.49 million. The teams earlier shared the $1 million 2006 Shaw Prize for the discovery of dark energy—which Science magazine had called “The Breakthrough Discovery of the Year” in 1998—and the Peter Gruber Foundation’s 2007 Cosmology Prize, a gold medal and $500,000, for the same discovery. Considered the most prestigious prize in the world, the Nobel has been awarded for achievements in physics, chemistry, physiology or medicine, literature and peace since 1901 by the Nobel Foundation in Stockholm. (The Nobel Memorial Prize in Economic Sciences was established in 1968 by the Central Bank of Sweden as a memorial to Alfred Nobel but is not one of the Nobel Prizes.) Riess was the 35th person associated with Johns Hopkins as a faculty member, fellow or graduate to win a Nobel Prize. He joins three other Nobel laureates on the university’s current faculty: Riccardo Giacconi, research professor of physics and astronomy, who won the physics prize in 2002; Peter Agre, a 1974 School of Medicine graduate, former professor in the School of Medicine and now director of the Malaria Research Institute in the Bloomberg School of Public Health, who won the chemistry prize in 2002; and Carol Greider, professor and director of Molecular Biology and Genetics in the School of Medicine, who won the 2009 prize in physiology or medicine.

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versity. Sponsored by Pathology. G01 BRB. EB Wed., Jan. 4, 3 p.m. “Turn ‘Bad Fat’ Into ‘Good Fat’: New Bullet Against Obesity and Diabetes,” a Pediatric Endocrinology seminar with Sheng Bi, SoM. Marburg Conference Room. EB Wed., Jan. 4, 4 p.m. “Mechanisms of Action of Antiproliferative Natural Product Triptolide,” a Pharmacology and Molecular Sciences thesis defense seminar with Denis Titov. 303 WBSB. EB

SPECIAL EVENTS

Sat., Dec. 24, 10 a.m. Observance at the gravesite of university founder Johns Hopkins. (See In Brief, p. 2.) Green Mount Cemetery (enter at main gate along Greenmount Ave). Fri., Jan. 6, noon. Martin Luther King Jr. Commemoration and Community Service Awards, with keynote speaker Martin Luther King III. (See story, p. 4.) Turner Concourse. EB

Wed., Jan. 4, noon.

Fri., Jan. 6, daylong. Medical Student Research Day showcasing student research and offering medical students an opportunity to present their findings to classmates and faculty. (See In Brief, p. 2.)

Armstrong Medical Education Building. EB • noon. Poster session; food and refreshments will be served. Main lobby and floors 2 and 3. • 1 p.m. Podium presentations. Lecture Hall. • 3 p.m. Poster session; food and refreshments will be served. Main lobby and floors 2 and 3. • 4:30 p.m. Keynote address by Jeremy Sugarman, deputy director, Berman Institute of Bioethics. Lecture Hall. • 5 p.m. Award ceremony. Lecture Hall.

(Events are free and Calendar open to the public Key except where indicated.) APL BRB CRB CSEB

Applied Physics Laboratory Broadway Research Building Cancer Research Building Computational Science and Engineering Building EB East Baltimore HW Homewood KSAS Krieger School of Arts and Sciences PCTB Preclinical Teaching Building SAIS School of Advanced International Studies SoM School of Medicine SoN School of Nursing SPH School of Public Health WBSB Wood Basic Science Building WSE Whiting School of Engineering

Pediatric heart transplants: Whites more likely to survive long term

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hite heart transplant patients under the age of 18 are more than twice as likely to be alive a decade after surgery as their African-American counterparts, new Johns Hopkins research suggests. The findings, part of a large-scale review of factors that appear to significantly influence long-term survival among pediatric heart transplant patients, were presented Nov. 13 at the American Heart Association’s annual Scientific Sessions in Orlando, Fla. “It’s unclear whether these racial disparities are due to biological differences or socioeconomic differences that have an impact

on access to care, or some combination of the two,” said Arman Kilic, a surgical resident at The Johns Hopkins Hospital. “That’s been hotly debated, but these data tell us we need to do a lot more research to figure out why those disparities exist and how we can narrow the gap.” Kilic analyzed United Network of Organ Sharing data from the 2,721 pediatric heart transplants performed in the United States between 1987 and 1999. Forty-two percent of patients (1,143) were alive 10 years or more after transplant. The average age of the recipients at the time of transplant was younger than 6.

In addition to racial disparities in longterm survival, the analysis showed that boys are 26 percent more likely than girls to survive a decade after their transplants; children who had their surgeries at hospitals where large numbers of transplants are done annually also were more likely to be alive 10 years later. For every 10 additional pediatric heart transplants conducted at a hospital each year, the chance of 10-year survival for patients transplanted there increased 36 percent. Patients at high-volume centers do better not only because their surgeons likely have more experience with heart transplants, Kilic said, but also because the staff and facilities are

likely better equipped to manage the complex post-operative care of these patients. The findings also show that patients transplanted later in the study period and those who got their hearts from younger donors were significantly more likely to survive long term. Those who were on mechanical ventilation prior to their transplant were less likely to live a decade than those who were breathing on their own before surgery. “Children are potentially a group of patients whose survival after transplantation could be several decades, so it’s especially important to better understand why some do well and others do not,” Kilic said. —Stephanie Desmon

The Gazette  

The official newspaper of The Johns Hopkins University

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