Page 1

o ur 3 9 th ye ar

D E S I G N ing S TUD E N T S


Covering Homewood, East Baltimore, Peabody,

Engineering majors put class-

Earth scientist aims to develop

SAIS, APL and other campuses throughout the

room-learned skills to work on

most advanced model of ocean

Baltimore-Washington area and abroad, since 1971.

real-world problems, page 5

currents ever made, page 7

May 10, 2010

The newspaper of The Johns Hopkins University


Push begins to ramp up health IT

Volume 39 No. 33


Trophies in bloom for spring teams

By Greg Rienzi

The Gazette

Continued on page 8




The undergdog Johns Hopkins squad takes the top spot at the Centennial Conference Women’s Track Championships.

By Greg Rienzi

The Gazette


he calendar flipped to May and titles began to pop up like tulips for the baseball, women’s track and field, and men’s and women’s tennis teams. In whirlwind fashion, Johns Hopkins

celebrated four Centennial Conference championships in one thrilling four-hour period on Sunday, May 2. Three of the squads now have national titles in their crosshairs. The baseball team continued its banner season with a 13-6 win over Haverford in the championship game of the Centennial Conference Tournament, held on the Homewood campus. The victory cemented the fourth straight

conference title for the Blue Jays, who are currently ranked No. 1 in the American Baseball Coaches Association and polls. They also earned the Centennial Conference’s automatic qualifier into the NCAA Tournament, which will start May 19. The team had a 38-3 record going into the weekend’s season-ending doubleContinued on page 8


ver wonder how a pharmacist deciphers a physician’s quickly scribbled notes on a prescription without making an error, or why in 2010 a fax machine is still needed to transmit a patient’s medical records? Now imagine an electronic prescripJH receives tion sent from the practioner’s $5.5 million cell phone, and a ARRA grants health clinic that can quickly retrieve a patient’s most to expand up-to-date medical records from a training credit card–shaped electronic chart that he carries with him. In the coming years, experts predict that such information technology will play a significantly larger role in the care and management of a person’s health. The federal government is giving a not-so-gentle push. Through Medicare and Medicaid, it will offer billions of dollars in incentives to hospitals and health care providers over the next five years to develop and implement health information technology, such as e-prescriptions and patientcentered electronic health records. To ramp up this development, a massive and highly trained work force will be needed. Johns Hopkins is set to do its part. University faculty recently received two federal grants—totaling more than $5.5 million—that will help put Johns Hopkins at the forefront of training in this expanding field. Harold Lehmann, associate professor at the School of Medicine and director of training and research for Johns Hopkins’ Division of Health Sciences Informatics, has been awarded $3.75 million to develop post-baccalaureate and master’s-level health IT work force training programs at the schools of Medicine, Public Health and Nursing. The grant was awarded under the Health Information Technology for

The Blue Jays baseball team celebrates its fourth consecutive Centennial Conference championship.

In Brief

Inventor James B. West receives prestigious honor; patient care symposium; SAP upgrade


C a l e nd a r

12 hours of Beethoven; celebrating 1,000th HRRT PET scan; home expo

10 Job Opportunities 10 Notices 11 Classifieds

2 THE GAZETTE • May 10, 2010 I N   B R I E F

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James B. West of WSE receives Benjamin Franklin Medal


ames B. West, a researcher in the Whiting Schoolâ&#x20AC;&#x2122;s Department of Electrical and Computer Engineering, has been awarded the 2010 Benjamin Franklin Medical Award in Electrical Engineering. The prestigious award was one of 11 presented this year by the Franklin Institute to honor accomplishments in science, technology and business. Since 1824, the Philadelphia-based institute, founded in honor of Benjamin Franklin, has given awards to many prominent figures, including Albert Einstein, Thomas Edison, Marie and Pierre Curie, Orville Wright and Jane Goodall. West was honored along with Gerhard M. Sessler of the Damstadt University of Technology in Germany, with whom he worked at Bell Laboratories and in 1962 invented the first practical and inexpensive electret microphone, which now serves as the basis of 90 percent of the more than 2 billion microphones produced annually, including those in professional microphones, cell phones, hearing aids, baby monitors and video cameras. West holds more than 40 U.S. patents and has received numerous awards. He was inducted into the National Inventors Hall of Fame in 1999. The black-tie award ceremony and dinner, considered to be one of the pre-eminent social events in Philadelphia, was held on April 29. Among the other 2010 recipients was Microsoft co-founder Bill Gates, who received the Bower Award for Business Leadership.

Academy of Clinical Excellence hosts patient care symposium


ast year, Johns Hopkins introduced a new initiativeâ&#x20AC;&#x201D;the first of its kindâ&#x20AC;&#x201D; to recognize clinically excellent academic physicians who have achieved a level of mastery in communication and interpersonal skills, professionalism and humanism, and negotiation of the health care system. Called the Miller-Coulson Academy of Clinical Excellence, it is based at Bayview Medical Center. The academy this week is hosting its second event, an Excellence in Patient Care Symposium. Attendees will have the opportunity to learn more about the academy and talk with physicians and patients about their experiences. Scheduled to speak are academy leaders, Bayview patients and Johns Hopkins medical students who will give their perspectives on patient care and clinical excellence. The Miller-Coulson Academy also will induct nine new members, who were chosen by their colleagues and an external review board in recognition of their excellence in patient care at Bayview. These physicians are Margaret S. Chisolm, Mark

Editor Lois Perschetz Writer Greg Rienzi Production Lynna Bright Copy Editor Ann Stiller Photography Homewood Photography A d v e rt i s i n g The Gazelle Group Business Dianne MacLeod C i r c u l at i o n Lynette Floyd Webmaster Tim Windsor

D. Duncan, Duvuru Geetha, H. Franklin Herlong, Eric E. Howell, Carl A. Johnson, Edward Kraus, Rafael H. Llinas and Steven J. Schwartz. In addition, Gurpreet Dhaliwal, of the University of California at San Francisco School of Medicine, will present â&#x20AC;&#x153;Clinical Judgmentâ&#x20AC;&#x201D;Good to Greatâ&#x20AC;? as part of medical grand rounds. The symposium is from 10:30 a.m. to 1 p.m. on Tuesday, May 11, in the Asthma & Allergy Center Auditorium at Bayview. To register or for more information, contact Katie Kuehn at or 410-550-0128.

SAIS team takes second place in development competition


SAIS team took second place in the inaugural Global Challenge competition hosted by USAID and the University of Marylandâ&#x20AC;&#x2122;s Robert H. Smith School of Business. The winning team members were Samiya Edwards, Naureen Kabir, Tzyy Ming Yeh and Tara Nicholson. The competition challenged teams of MBA and other graduate students to develop a public-private venture to support development and the tourism industry in Asia. The SAIS team proposed a Cambodian wildlife sanctuary and ecolodge. The eight finalist teams were selected from 65 registered teams across 32 universities. For more on the teamâ&#x20AC;&#x2122;s proposal and to see its presentation slides, go to www.rhsmith .aspx.

SAP upgrade to begin after business hours on Friday


uring its software upgrade, SAP will be unavailable from after business hours on Friday, May 14, until the morning of Wednesday, May 19. This downtime will include all SAP components such as the shopping cart, business warehouse reports and internal service requests. During this time, users will not be able to use SAP to view transactions, make purchases, process new hires or run reports.

Moving company launched by student entrepreneurs


ust in time for end-of-year office and lab moves, a new student-run moving service for faculty and staff has been launched as part of Hopkins Student Enterprises, through the Center for Leadership Education in the Whiting School of Engineering. Hopkins Student Storage (www handles packing, transportation and storage; pricing, which starts at $50 an hour, is based on number of movers and duration of the job.

Contributing Writers Applied Physics Laboratoryâ&#x20AC;&#x2C6; Michael Buckley, Paulette Campbell Bloomberg School of Public Health Tim Parsons, Natalie Wood-Wright Carey Business School Andrew Blumberg Homewood Lisa De Nike, Amy Lunday, Dennis Oâ&#x20AC;&#x2122;Shea, Tracey A. Reeves, Phil Sneiderman Johns Hopkins Medicine Christen Brownlee, Stephanie Desmon, Neil A. Grauer, Audrey Huang, John Lazarou, David March, Katerina Pesheva, Vanessa Wasta, Maryalice Yakutchik Peabody Institute Richard Selden SAIS Felisa Neuringer Klubes School of Education James Campbell, Theresa Norton School of Nursing Kelly Brooks-Staub University Libraries and Museums Brian Shields, Heather Egan Stalfort

The Gazette is published weekly September through May and biweekly June through August for the Johns Hopkins University community by the Office of Government, Community and Public Affairs, Suite 540, 901 S. Bond St., Baltimore, MD 21231, in cooperation with all university divisions. Subscriptions are $26 per year. Deadline for calendar items, notices and classifieds (free to JHU faculty, staff and students) is noon Monday, one week prior to publication date. Phone: 443-287-9900 Fax: 443-287-9920 General e-mail: Classifieds e-mail: On the Web: Paid advertising, which does not represent any endorsement by the university, is handled by the Gazelle Group at 410343-3362 or

May 10, 2010 • THE GAZETTE



KSAS scores big with ACLS New Faculty Fellows program B y A m y L u n d ay



he Krieger School of Arts and Sciences and four of its recent graduates are benefiting from a new initiative addressing the tough job market facing today’s young PhDs. The American Council of Learned Societies’ New Faculty Fellows program is providing two-year positions, with annual stipends of $50,000, to 50 recently minted doctors of the humanities and humanistic social sciences; four of the fellows earned their doctorates from the Krieger School, and two additional fellows with degrees from other institutions will be appointed to departments in the Krieger School this fall. Thanks to the program, Mary Ashburn Miller, who defended her doctoral thesis in history in July 2008, will remain at Reed College, where she has been a visiting assistant professor of history since earning her degree. Alison Calhoun, who earned both her bachelor’s and doctorate in French at Johns Hopkins, in 2002 and 2008, is headed to the Department of French and Italian at Indiana University, Bloomington, after a year as a visiting assistant professor of French at Pomona College. She’ll join two professors who are also Johns Hopkins alumni. Molly Warnock, who earned a joint PhD in intellectual history and art history through

both the Humanities Center and the History of Art Department in 2008, has been appointed to the Department of Art History at the University of Chicago, after spending two years as a postdoctoral research fellow in the Department of Art and Archaeology at Princeton University. And Jacquelyn Williamson, who in November 2008 defended her doctoral thesis in Egyptology through the Department of Near Eastern Studies, will be appointed to the Department of Near Eastern Studies at the University of California, Berkeley, after wrapping up a twoyear archaeological field project in Karnak Temple in Luxor, Egypt, where she has been an assistant field director with the American Research Center. Joining the Krieger School’s History of Art faculty will be Christopher Lakey, who earned his doctorate at Berkeley. The Department of English will appoint Ashley Marshall, who earned her doctorate at Pennsylvania State University, University Park. Designed to address scholars’ employment challenges while also supporting teaching at universities and colleges, the American Council of Learned Societies’ New Faculty Fellows program commits participants to teaching three semester-length courses each year in exchange for their $50,000 stipend, a $5,000 annual research and travel allowance, health insurance and a $1,500 one-time moving allowance. The program is supported by the Andrew W. Mellon Foundation.

Greg Ball, dean of research and graduate education in the Krieger School and a professor in the Department of Psychological and Brain Sciences, served as the university’s liaison for the new faculty fellows program. In the inaugural year, nominees were limited to graduates of the 60 U.S. members of the Association of American Universities and had to have earned their degrees between Jan. 1, 2008, and Dec. 31, 2009. The fellows were selected based on a rigorous review process managed by the ACLS; reviewers were recruited from AAU member universities. AAU institutions, along with select undergraduate colleges, were then allowed to recruit fellows and extend offers. The fellows either visited campuses or were interviewed virtually via Skype to weigh the pros and cons of the choices before them. The Krieger School was allowed to nominate only 10 of its recent graduates, and to have secured positions for four of them is an outstanding achievement, Ball said. “I am delighted that our success rate in the ACLS fellows’ competition was so high. Only one other university, with five fellows selected from more nominees than Hopkins was allowed, surpassed us,” Ball said. “It is another indication of the excellence of our programs in the humanities. I am also pleased that we were able to attract two outstanding scholars who will contribute to our teaching and scholarly activities in the coming two years.”

The Johns Hopkins–educated faculty fellows said that they are grateful for the opportunities the program offers, not just for the paycheck and stability but for the chance to continue pursuing their research. “This was a difficult competition because not only were there only 50 [fellows] selected out of 800 [nominees], there was also an initial selection process by each candidate’s home institution,” said Calhoun, whose doctoral adviser, Michel Jeanneret, alerted her to the program. “I was slightly more nervous about the JHU selection than the actual competition. Despite a tough market, I knew it meant two years of job security in a meaningful and fulfilling position in my field, [and] a promising way to grow in one’s teaching and publishing while waiting for more jobs to present themselves.” For Miller, whose book, A Natural History of Revolution, is due to be published next year by Cornell University Press, the fellowship will provide her with resources to pursue her next research project, which she’ll begin with a trip to Paris this summer. “Through the interview process, the fellowship has given me the opportunity to speak with some of the most highly respected scholars in my field and to get feedback on my work from scholars all over the country. Most importantly, however, it has given me an opportunity to continue doing what I have come to love: research and teaching as a historian.”

Johns Hopkins to unveil Center for Biotechnology Education B y K e n S c h a pp e l l e

Advanced Academic Programs


he Krieger School of Arts and Sciences’ Advanced Academic Programs will unveil the Center for Biotechnology Education this week at its fifth annual biotechnology research symposium, to be held on the university’s Montgomery County Campus. The center will expand the scope of Johns Hopkins’ biotechnology education by adding symposia, workshops, youth development programs and noncredit training to its current offering of graduate degrees, and master’s certificates and fellowships.

“The Johns Hopkins University has long played a significant role in scientific research and discovery,” said Patrick Cummings, director of the center and senior associate program chair of the MS in Biotechnology program. “In that tradition, we created the Center for Biotechnology Education to help share the knowledge and resources of our premier research institution with students, working professionals, teachers and the general public.” The establishment of the center positions Johns Hopkins at the forefront of educational continuum for regional, national and international biotechnology programming and leadership. “The center is working to forge strong

partnerships with industry and government organizations, area school districts and other Johns Hopkins entities,” said Dick McCarty, chair of the center and chair of AAP’s Advanced Biotechnology Studies program. “Our goal is to build a pipeline of students and professionals equipped to achieve success in K–12 education, graduate school and the workplace in the fields of biotechnology, bioinformatics, bioscience regulatory affairs, and bioscience business and leadership.” The center’s inaugural event will take place from 5:30 to 8:30 p.m. on Thursday, May 13, in Gilchrist Hall. The event will feature keynote speaker Jesse Goodman, chief scientist and deputy commissioner for science and public health at the U.S. Food

and Drug Administration, and poster presentations from area high school students and from Johns Hopkins biotechnology, bioinformatics and regulatory affairs master’s degree students. The administrative offices for the center are in the Wyman Park Building on the Homewood campus. To serve its surrounding community, the center also has an office on the Montgomery County Campus, which has a state-of-the-art laboratory for graduate student training and for workshops, as well as a dedicated computer laboratory for bioinformatics workshops. For more information, go to biotechnology or e-mail

Craig, Yau of SoM elected to National Academy of Sciences By Mary Alice Yakutchik

Johns Hopkins Medicine


ancy L. Craig, a professor of molecular biology and genetics, and King-Wai Yau, a professor of neuroscience and ophthalmology, both in the Johns Hopkins University School of Medicine, are among 72 scientists nationwide newly elected to membership in the National Academy of Sciences, an honorary society that advises the government on scientific matters. “Johns Hopkins is very proud that the academy has chosen to recognize Nancy and King-Wai,” said Stephen Desiderio, director of the Johns Hopkins Institute for Basic Biomedical Sciences. “Both have made seminal discoveries in their respective fields over the years, and their elections are well-deserved.” A Howard Hughes Medical Institute investigator, Craig studies the molecular mechanisms by which so-called transposable elements move and how they can be exploited for genetic engineering. Com-

posed of DNA sequences with no fixed address, these traveling salesmen of the genome are present in virtually all organisms and contribute to both genome structure and function. One important consequence of transposon insertion is that information encoded by the transposon becomes stably linked with its DNA target. About one half of the human genome is composed of DNA sequences related to transposable elements, which are emerging as potentially important predictors of human traits and diseases. Craig currently is focusing her research efforts on how several different transposons choose their new insertion sites. Craig joined the Johns Hopkins faculty in 1991 and was previously a faculty member in the Department of Microbiology and Immunology at the University of California, San Francisco. She earned a bachelor’s degree in biology and chemistry from Bryn Mawr College and a doctorate in biochemistry from Cornell University. Yau’s primary research interest lies in the flow of signals important in sight and smell. Among his discoveries are the critical roles played by two key signaling molecules—

calcium and cyclic GMP—in the process of converting light into electrical signals by the rod and cone photoreceptor cells in the retina, a process known as visual transduction. In addition to advancing the understanding of hereditary blinding diseases that affect rod and cone cells, Yau characterized the light-response behaviors of a newly discovered photoreceptor cell in the retina. These cells can react to light and affect circadian rhythms and other nonvisual aspects of the brain’s visual system. Yau also contributed to finding the cause of one form of central vision loss. Yau, who joined the Johns Hopkins faculty in 1986, earned a bachelor’s degree in physics from Princeton University and a doctorate in neurobiology from Harvard University. “Nancy’s and King-Wai’s election to the academy attests to the strength of the research enterprise at Johns Hopkins,” said Chi V. Dang, vice dean for research. “We couldn’t be happier for them.” The election of Craig and Yau, held during the 147th annual meeting of the academy in Washington, D.C., brings the total

number of active members to 2,097. The National Academy of Sciences is a private organization of scientists and engineers dedicated to the furtherance of science and its use for the general welfare. It was established in 1863 by a congressional act of incorporation signed by Abraham Lincoln that calls on the academy to act as an official adviser to the federal government, upon request, in any matter of science or technology.

Related Web sites Nancy Craig: welcome.html

King-Wai Yau: KingWaiYau.php

National Academy of Sciences: PageServer

4 THE GAZETTE • May 10, 2010

Spouses caring for partners with dementia at risk of same fate B y C h r i s t e n B r o wn


Johns Hopkins Medicine


usbands or wives who care for spouses with dementia are six times more likely to develop the memory-impairing condition than those whose spouses don’t have it, according to results of a 12-year study led by Johns Hopkins, Utah State and Duke universities. The increased risk that the researchers saw among caregivers was on par with the power of a gene variant known to increase

susceptibility to Alzheimer’s disease, they report in the May Journal of the American Geriatrics Society. A few small studies have suggested that spousal caregivers frequently show memory deficits greater than spouses who aren’t caregivers. None, however, examined the cognitive ability of caregivers over time using standard, strict criteria to diagnose dementia, a serious cognitive disorder characterized by deficits in memory, attention, judgment, language and other abilities. To get some answers, Peter Rabins, a professor of psychiatry at the Johns Hopkins School of Medicine, and a team led by Maria Norton, an associate professor in the Department of Family, Consumer and Human Development at Utah State University, examined 1,221 married couples ages 65 or older. These individuals were part of

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the Cache County (Utah) Memory Study, which since 1995 has identified more than 900 persons with dementia in the community, whose residents topped the longevity scale in the 1990 U.S. census. Volunteers being screened by researchers for dementia first completed questionnaires to evaluate their cognitive status. Those whose questionnaires suggested possible dementia underwent a comprehensive clinical assessment administered by specially trained nurses and technicians. Finally, a team led by a geriatric psychiatrist and a neuropsychologist evaluated the findings and assigned a diagnosis of dementia where appropriate. In the sample of 2,442 married persons, the researchers diagnosed 255 individuals with dementia and discovered that individuals whose spouses had already been diagnosed were six times as likely to develop the condition themselves compared to those without an affected spouse. This increased risk is comparable to the risk of developing Alzheimer’s disease associated with a well-studied gene variant known as APOE ε4, the researchers report. The findings held up even when the researchers accounted for other factors that might influence the risk of developing dementia, such as socioeconomic status. Norton says that the long-term nature of the new research makes the results different from earlier “snapshot” studies showing memory loss in spousal caregivers. “We know that the declines in memory we saw were real and persistent, not just a point in time where [the subjects] weren’t performing well on tests,” she says. A strength of the Cache County Study, Rabins notes, is that the findings are highly representative of the community because the vast majority of residents age 65 or older

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are participating in ongoing research. Earlier studies often relied on results from patients of memory centers and their caregivers, a sample that might not typify the community at large. Rabins, Norton and their colleagues speculate that the stress of care giving might be responsible for the increased dementia risk for spouses, although more research is needed to identify what that mechanism might be. If their hunch is correct, Rabins says, doctors who treat dementia patients should pay more attention to efforts to decrease stress for spousal caregivers. “Care giving has positive aspects as well as negative ones. If we can boost the positive aspects and reduce the negative ones, we may be able to reduce a caregiver’s risk of developing dementia,” Rabins says. Researchers have long been interested in how taking care of a spouse with dementia affects caregivers. Most previous studies have focused on the emotional distress caretakers often experience rather than how their cognitive abilities might be affected.

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Researchers speculate that stress of care giving may be to blame

May 10, 2010 • THE GAZETTE D E S I G N



jay vanrensselaer / HOMEWOODPHOTO.JHU.EDU

jay vanrensselaer / HOMEWOODPHOTO.JHU.EDU

Engineering students seek to solve real-world challenges

Qing Xiang Yee explains his team’s Improved Eye Medication Applicator concept to Helen Neese.

Christine Shultz demonstrates the lifting device that Tristan Arbus, Diana Sandy and Adam Sierakowski, looking on, invented for her wheelchair.

By Phil Sneiderman

Department of Biomedical Engineering, said. He praised the initiative for the way it “cuts across many institutional boundaries” by encouraging team efforts involving students and faculty in the Engineering School and the School of Medicine. Addressing the attendees, Johns Hopkins University President Ronald J. Daniels said that the program perfectly embodies the ideal of “one university.” Alfred E. Mann, a highly successful biomedical engineering businessman and philanthropist, was the keynote speaker. He encouraged students to take on technical challenges in an untapped, fast-growing market and produce superior products. Toward this goal, the university has established the Center for Bioengineering Innovation and Design, which aims to help students recognize unmet needs for medical tools and devices, and helps steer them through the development of prototypes and possible commercialization. Most of the projects presented during last week’s biomedical engineering student design showcase reflected this approach. The first-place undergraduate presentation award went to the Improved Eye Medication Applicator team, led by Eugene Lee and Jan Lee. Second-place honors went to the Rapid Hypothermia Induction Device team, led by David Huberdeau. Third-place winner was the Stem Cell Therapy for Soft Tissue Defects team, led by Nicholas Gill. The best-poster award went to the Cor-



uring two engineering design showcases held last week on the Homewood and East Baltimore campuses, many Whiting School students demonstrated that they were aiming for the stars. Sometimes, literally: One team built mechanical legs to help a future spacecraft land gently on the moon. Other teams targeted the moon figuratively by designing devices that may prevent thousands of premature births or crafting tools that could lead to safer surgical procedures for vast numbers of people. But at least one team sought a far more down-to-earth goal: finding a way to make life a little easier for one 18-year-old Maryland woman who has cerebral palsy. Three mechanical engineering undergraduates, dubbed Team Grab Bag, devised a motorized mechanism that can lift the young woman’s purse, books and other possessions from an out-of-reach position behind her wheelchair to a resting place in the front of her chair, where she can easily access her belongings. “I love it!” said Christine Shultz of Annapolis, an Old Mill High School student who has limited mobility. “Before, I had to have someone reach in back of my chair to get my stuff for me. [With this device,] I have more independence. I can do things by myself. Everything works wonderfully.”

Shultz said she plans to use the device, which can lift about 30 pounds, to retrieve her lunch bag, laptop and other items when she continues her studies this fall at a community college. On May 4, Shultz was a special guest at the Mechanical Engineering Department’s annual Senior Design Day on the Homewood campus. Among the 11 yearlong team projects presented at the event, her wheelchair accessory was awarded the first-place prize. For the three inventors from Team Grab Bag—Tristan Arbus, Diana Sandy and Adam Sierakowski—this honor and the results of their work were especially rewarding. “It felt great to be able to help Christine and her family,” Arbus said. “We were very proud of what we could do for them.” Although this particular arrangement of motors, actuators and electronics was customized for Shultz, the students believe it could easily be adapted to other wheelchairs, and they are taking steps toward patenting their design. The project was sponsored by Baltimore-based Volunteers for Medical Engineering. On the same day that the mechanical engineering designs went on display at the Homewood campus, a dozen biomedical engineering projects were presented during BME’s Student Design Day, held this year on the East Baltimore campus. “This is probably my favorite day of the year,” Elliot McVeigh, director of the

tical Concepts team, made up of master’s degree students Evan Luxon, Jason Hsu, Nicolas Martinez and Christopher Komanski. In the poster competition’s undergraduate division, the first-place winner was the Modified Capsule Endoscopy for Seek-andTreat Therapy team, led by Erica Jantho and Abhiram Bhashyam. Second place went to the Intelligent Surgical Drill team, led by Leyla Isik. The third-place winner was the Minimally Invasive Spinal Disc Decompression team, led by Alice Wu and James Wang. Within the Whiting School of Engineering, senior design or capstone projects are a common educational requirement, encouraging students to apply their classroom skills to a hands-on assignment similar to those they may encounter in the working world.

Related Web sites Christine tries out the system for the first time: watch?v=ZaDom6cLwq4

A team member tests the system on the Homewood campus: watch?v=6o_shHNLsqs

Despite tests, high blood pressure hard to recognize in children B y K at e r i n a P e s h e va

Johns Hopkins Medicine


Johns Hopkins Children’s Center study of 2,500 patient records suggests that medical staff fail to check a child’s blood pressure a fifth of the time and, in those whose blood pressure they do check, they are not recognizing what constitutes an abnormal reading. Researchers say the consequences are that pediatricians and nurses may be missing the development of hypertension and its serious consequences, even when they do take blood pressure measurements. The American Academy of Pediatrics’ guidelines call for regular blood pressure checks in children 3 years and older to screen for elevated blood pressure and say that elevated blood pressure on three consecutive medical visits qualifies as hypertension. Even a single episode of high blood pressure can indicate hypertension and should trigger repeat measurements during the visit and subsequent doctor visits, the academy says. The problem is that measuring blood

pressure in a child is far more complicated than in an adult and requires interpreting each individual measure against a reference table for age, gender and height, says lead investigator Tammy Brady, a nephrologist at the Johns Hopkins Children’s Center. The researchers analyzed 2,500 records of visits to the pediatrician’s office. Medical staff did not check blood pressure in 500 of the cases. Elevated blood pressure scores were recorded in 726 cases of the 2,000 measurements taken, but the implications went unrecognized and unremarked upon in 87 percent of them, the study found. The findings, to be published in June’s Pediatrics and appearing online May 3, underscore the need for better recognition and aggressive monitoring of all children to prevent both the short- and long-term complications of hypertension, the investigators say. The study found that medical staff were more likely to miss elevated blood pressures in children of normal weight and in those without a family history of cardiovascular disease. The same was true for those children whose blood pressure was at or below 120/80, a score considered ideal in adults

but one that may portend trouble in a child, depending on height, gender and age. Blood pressure parameters in adults are clearly defined, but the complicated arithmetic involved in children’s blood pressure may be one of the greatest barriers to recognizing a child’s elevated pressure, the investigators say. Brady says that more education and automated systems that alert the medical staff if a child’s blood pressure is out of range can help. Johns Hopkins Children’s Center is currently testing one such alert system and will soon publish data on its effectiveness. Hypertension, defined as persistently elevated blood pressure, can cause kidney, eye and heart damage, but while some complications take years and decades to develop, certain ones evolve quickly, the researchers say. A dangerous thickening of the heart muscle called left-ventricular hypertrophy can develop in a matter of months in children with untreated hypertension, but is reversible with early treatment. Because high blood pressure rarely causes symptoms, medical staff may overlook a child who has no traditional risk factors, such as obesity or family history, the researchers say.

Half the children in the study with elevated blood pressure were of normal weight. “Nurses and doctors may be so falsely reassured by a child’s lack of symptoms and risk factors that they either miss milder elevations or may chalk them up to measurement error and never follow up on them,” Brady said. In the study, covering children ages 3 to 20 visiting a primary care pediatric clinic at Johns Hopkins, high blood pressure was discovered in 6 percent of healthy-weight children and in 20 percent of overweight and obese children. Even though medical staff were more attentive to elevated blood pressure among overweight and obese children, high blood pressure was still missed in four out of five of them. Children with scores below 120/80 were nearly eight times more likely to have their high blood pressure missed than children with blood pressure above 120/80. Children without a family history of cardiovascular disease were twice as likely to have their high blood pressure unrecognized as those with family history. The research was funded by the American Kidney Fund, National Kidney Foundation and National Institutes of Health.

6 THE GAZETTE • May 10, 2010

Social context may affect obesity disparities more than race


hen analyzing obesity disparities among women, socioeconomic status and social context may be more important than race, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health’s Center for Health Disparities Solutions. The authors examined race disparities in obesity among black and white women living in the same social context with similar income and compared these estimates to national data. Nationwide, black women were twice as likely to be obese when compared to white women. However, the researchers found that obesity rates were comparable in a sample of white and black women living in similar social and environ-

mental conditions. The results are featured in the May issue of the Journal of Epidemiology and Community Health. “In a national sample not accounting for race differences in social context, black women had twice the chance of being obese as compared to white women,” said lead author Sara Bleich, an assistant professor in the Bloomberg School’s Department of Health Policy and Management. “To date, efforts to explain the disparity in obesity prevalence have primarily focused on individuallevel factors, and little research has focused on social context as a possible explanation. When we examined poor urban women exposed to the same environment, race disparities in obesity virtually disappeared.” Bleich and colleagues from the Center for Health Disparities Solutions examined race

disparities in obesity among black and white women living in the same social context with similar income in Baltimore. Using the data from the Exploring Health Disparities in Integrated Communities–Southwest Baltimore study, a cross-sectional face-to-face survey of adults ages 18 and older, researchers compared estimates to national data from the National Health Interview Survey to determine if the race disparity in obesity was attenuated among women living in the same social context. Obesity was calculated from self-reported height and body weight, and logistic regression was used to examine the association between race and obesity. “Accurately accounting for social and environmental exposures is particularly important for the study of obesity disparities given the growing literature linking individual body

weight to a host of environmental factors both positively and negatively associated with body mass index,” said Thomas LaVeist, senior author of the study and director of the Center for Health Disparities Solutions. “Developing policies that focus on modifying social aspects of the environment may reduce disparities in obesity among low-income women living in urban communities.” The study was written by Bleich, Roland Thorpe, Hamidah Sharif-Harris, Ruth Fesahzion and LaVeist. The research was supported by the National Center on Minority Health and Health Disparities of the National Institutes of Health, Pfizer, the National Heart Lung and Blood Institute and the Health Disparities Loan Repayment Program. —Natalie Wood-Wright

Parents favor e-mail access to child’s pediatrician, study finds


iven the option, most parents would gladly e-mail their child’s pediatrician with nonurgent questions about minor ailments or symptoms, medication, feeding, sleeping and follow-up appointments, according to a preliminary small survey conducted by Johns Hopkins Children’s Center. The study’s findings were presented May 2 at the annual meeting of the Pediatric Academic Societies, held in Vancouver, British Columbia. In the survey of 229 parents of children seen at Johns Hopkins, 171 described themselves as regular e-mail users. Of these, nearly 90 percent said they would welcome e-mail as a way to communicate with their child’s

doctor; only 11 percent said they currently do so. Three-quarters of the 171 said that e-mail would improve communication and increase contact between parents and doctors. While e-mail and text messaging remain uncommon in pediatric practices, the Johns Hopkins investigators say that it is likely only a matter of time before their use becomes widespread. The researchers caution that AfricanAmerican parents and those with annual household incomes of $30,000 or less were less likely to endorse e-mail as a desired mode of communication with their pediatricians. African-American parents, in particular, were more skeptical than white parents about e-mail and its capability to improve communication with doctors. Black parents

were 68 percent less likely than white parents to describe e-mail as a satisfying form of communication, and were 66 percent less likely to endorse it as a good communication device between parents and pediatricians. Although the study did not explore the reasons for their reluctance, the researchers say that the finding somewhat surprised them and clearly begs further research before adopting e-mail as a mainstream tool of doctor-patient communication. “The last thing we want to do is inadvertently create a gap in access or communication between those who use e-mail regularly and those who shun it, and before we incorporate e-mail into mainstream medical practice, we need to factor in any racial, cultural or socioeconomic preferences,” said

lead researcher Michael Crocetti. Crocetti communicates via e-mail with about a quarter of his patients’ parents. One-third of the parents surveyed who regularly use e-mail had a child with a chronic condition. Among these parents, 65 percent said they would strongly favor e-mail communication with their pediatrician to improve management of their child’s condition, but less than half said they would be comfortable receiving test results via e-mail. The Johns Hopkins investigators are planning a study of pediatricians’ attitudes toward e-mail. Robert Dudas, of the Johns Hopkins Bayview Medical Center, was co-investigator on the research. —Katerina Pesheva

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May 10, 2010 • THE GAZETTE A R R A



Charting ocean currents with a cutting-edge supercomputer This is part of an occasional series on Johns Hopkins research funded by the American Recovery and Revitalization Act of 2009. If you have a study you would like to be considered for inclusion, contact Lisa De Nike at lde@jhu .edu. By Lisa De Nike





sing a $736,000 grant administered through the federal stimulus act, a Johns Hopkins earth scientist is working with researchers at the Massachusetts Institute of Technology to develop what promises to be the biggest, most cutting-edge and detailed computer model of ocean currents ever made. The supercomputer model, which will be run by a National Science Foundation– built supercomputer capable of doing a million billion calculations per second, will simulate currents in the Arctic, Antarctic and Atlantic oceans in hopes of shedding light on how small-scale turbulent eddies affect large currents, such as the powerful Gulf Stream. This five-year study is important research because the ocean circulation plays a critical role in the Earth’s climate, according to principal investigator Thomas Haine, a professor in the Morton K. Blaustein Department of Earth and Planetary Sciences at Johns Hopkins. “There is an intricate, coupled relationship between climate and the ocean. The ocean circulation changes as the climate changes, but the climate changes as the ocean circulation changes. So if we want to better understand climate change in the past, present and future, we need to better understand ocean circulation,” Haine said. In addition to shedding light on ocean currents and their characteristics and behavior, the project has a technical goal: to build software that allows other researchers to exploit peta-scale supercomputers for science. (“Peta” in peta-scale means 1 followed by 15 zeros; so “peta-scale” means 1,000,000,000,000,000 calculations per second and 1,000,000,000,000,000 numbers stored. That’s like everyone on the planet

Thomas Haine with the apparatus he uses to demonstrate ocean circulation to his classes. The water tank shows eddies (swirls of food coloring) that are strongly affected by the spin of the tank. The eddies are analogous to the turbulent ocean eddies that the team will study in PAVE, the Peta-scale Arctic-Atlantic-Antarctic Virtual Experiment. In ocean eddies, the Earth’s spin is a dominant effect.

doing 100,000 different sums every second, and having a telephone directory of numbers that isn’t two inches thick but stretches all the way around the Earth.) “Traditional scientific inquiry is being revolutionized by computing, and scientific computing and numerical simulation are becoming so important that they actually rival laboratory experiments and mathematical theory as tools for new progress,” Haine said. “There is an urgent national interest in designing, building and operating the biggest, fastest computers on Earth, and the group funding us and our circulation project is one element of this race.” The present-day observations of the ocean (done by satellites, ships and robotic instruments) have large gaps between them, in space and in time. The team will view the high-resolution computer simulations in the same way that the present-day observing system views the real ocean. Comparing this sparsely sampled view with the fully resolved computer results will allow scientists to see those phenomena that the real observing system captures, and those that it misses. 1 0

According to Haine, simulating ocean currents is challenging for a number of reasons. One is that ocean basins have highly complex, irregular shapes, and it is imperative to get those details right in order for the calculations to be accurate. Another is that ocean currents interact in multifaceted ways with other components of the Earth’s climate system, including the atmosphere and the cryosphere (the portions of the Earth that include ice, snow cover,

glaciers, ice sheets and caps and permafrost). “Even though ocean circulation equations have been known since the 1880s, there is still a remarkable opportunity to make discoveries about how turbulent currents interact and evolve,” he explained. “By understanding circulation better, we can understand how other geophysical fluids work, too, like the Earth’s core, or Jupiter’s red spot or the sun’s photosphere.” Haine’s team’s investigations are among the 380 stimulus-funded research grants and supplements totaling $192 million that Johns Hopkins has garnered since Congress passed the American Recovery and Reinvestment Act of 2009 (informally known by the acronym ARRA), bestowing the National Institutes of Health and the National Science Foundation with $12.4 billion in extra money to underwrite research grants by September 2010. The stimulus package—which provided $550 billion in new spending, including the above grant—is part of the federal government’s attempt to bring back a stumbling economy by distributing dollars for transportation projects, infrastructure building, the development of new energy sources and job creation, and financing research that will benefit humankind. Johns Hopkins scientists have submitted about 1,300 proposals for stimulus-funded investigations, ranging from strategies to help recovering addicts stay sober and the role that certain proteins play in the development of muscular dystrophy to mouse studies seeking to understand how men and women differ in their response to the influenza virus. As of March 15, 120 staff jobs have been created directly at Johns Hopkins from ARRA funding, not counting those saved when other grants ran out, and not counting faculty and grad student positions supported by the ARRA grants.

1 7

Calendar Continued from page 12 Tues., May 11, 10:30 a.m. to 1 p.m.

Excellence in Patient Care, a Miller-Coulson Academy of Clinical Excellence at Bayview symposium with physicians, patients and Hopkins medical students and featuring medical grand rounds on the topic “Clinical Judgment—Good to Great” with Gurpreet Dhaliwal, University of California, San Francisco School of Medicine. (See “In Brief,” p. 2.) Asthma and Allergy Center Auditorium. Bayview

The 2010 P.H.A.S.E. Symposium, presentation of research by Bloomberg School of Public Health students who interned with the Maryland State Department of Health and Mental Hygiene during the 2009–2010 school year. Co-sponsored by the Mid-Atlantic Public Health Train-

Fri., May 14, 8 a.m. to 1 p.m.

ing Center and the Maryland Department of Health and Mental Hygiene. Conference Room L3, 1st floor, 201 W. Preston St. W OR K S HO P S

Mon., May 10, 9 a.m. to 2 p.m.

“Writing for Publication,” a Professional Development workshop designed to demystify publishing research. Intended for JHMI faculty, postdoctoral and clinical fellows. To register or for more information, go to www.hopkinsmedicine .org/pdo. Mountcastle Auditorium. EB Mon., May 10, 3:45 p.m. “Writing NSF Grants,” a Homewood Postdoctoral Association workshop with Dan Rabinovich, National Science Foundation; Noah Cowan, WSE; and Judith MitraniReiser, WSE. 100 Mudd. HW


jay vanrensselaer /

8 THE GAZETTE • May 10, 2010

The women’s tennis team takes its fourth straight title and earns the Centennial Conference’s automatic berth in the NCAA Tournament.

Continued from page 1 header versus Salisbury and went a perfect 21-0 against Centennial Conference opponents. The Blue Jays’ current winning streak of 31 games is the second longest in school history. The 2004 team won 33 consecutive games. While the baseball team is a perennial powerhouse, the women’s track team is building a new tradition of excellence. In the 2010 Centennial Conference Women’s Track Championships, held in Swarthmore, Pa., Haverford College sought its fifth straight outdoor title and 10th straight overall track championship—indoor and outdoor combined. The underdog Johns Hopkins squad would have something to say about that. The Blue Jays secured their first conference title in school history as they edged Haverford 190-185 in the final team standings. Johns Hopkins held off the heavily favored Haverford team, which roared back from a huge deficit. The big moment came in the 5,000-

Health IT Continued from page 1 Eco­nomic and Clinical Health Act, part of the 2009 American Recovery and Reinvestment Act. Patricia Abbott, an associate professor of health systems and outcomes in the School of Nursing, and Jonathan Weiner, professor of health policy and management at the Bloomberg School of Public Health, will co-direct the grant. The program’s goal is to rapidly increase the availability of people qualified to serve in health information technology roles in all health care settings to enhance patient care and population health. “There is bipartisan support for this initiative and lots of data that tell us that health IT can help save lives—and isn’t that what we’re trying to do?” Lehmann said. “I have no doubt that good health IT will promote quality care. We feel it will enhance patient safety and ultimately save money.” Health information technology, Lehmann said, can reduce paperwork and help eliminate medical errors by transmitting accurate and timely information to health care providers. “Currently, there is no integration. Many people see more than one doctor, and for their physicians to share information requires a lot of time-consuming back-andforth. Faxes need to be sent, forms signed,” he said. “Now picture a database a medical provider can use to see all your records, including your most recent visit to your primary care physician.” Abbott points out that patients are obtain-



meter run, the second-to-last event. Down by eight points, the Johns Hopkins trio of senior Laura Paulsen, freshman Liz Provost and sophomore Cecilia Furlong had to face off against Haverford’s Emily Lipman, the reigning conference cross-country champion. The JHU runners grabbed three of

the top five spots in the event, with Paulsen taking first with a time of 17:58.30. The team next needed to finish no worse than eighth in the nine-team field in the 4x400. The foursome of freshmen Amelia Vallenilla and Leah Sibener, sophomore Stephanie Chung and junior Anita Mikkilineni clocked in at 4:03 to place sixth and secure the title. Paulsen was named the meet’s Outstanding Track Performer after claiming her third individual title of the weekend with a firstplace finish in the 1,500-meter run. The title caps a storybook year for the track and cross-country teams under head coach Bobby Van Allen. The team claimed the Centennial Conference women’s cross country title in the fall and finished second at the CC Indoor Championships in the winter. The tennis teams served up more celebrations. The Johns Hopkins women’s team blanked visiting Swarthmore 5-0 in the title match of the 2010 Centennial Conference Championship to win its fourth straight title. The feat is one shy of the record five consecutive titles held by both Franklin & Marshall and Swarthmore. In singles action, freshman Candace Wu quickly pushed Hopkins’ lead in the match to 4-0 with a 6-0, 6-1 win. Freshman Nandita Krishnan then closed out the match with a 6-0, 6-0 win over her opponent. With

The men’s tennis team wins its fourth straight trophy and fifth in the last six years and heads to the NCAA Tournament.

ing care in a variety of settings, from the home to the hospital, to the nurse-managed clinic in the neighborhood. “It is critically important that we capture all of the data related to patient care, regardless of locale,” she said. “If we fail to coalesce the data, then we will continue to propagate waste and inefficiency while increasing the chances of medical error.” Lehmann said that a great many people will be needed to develop and manage innovative applications of information technology and information systems that address biological, clinical or public health priorities, and to study how the information is organized and used. Johns Hopkins is one of nine universities awarded funds to advance this training. The university will specifically use this grant to further develop informatics courses already offered across the three schools and to offer partial funding to students. The grant emphasizes shorter-format programs, such as certificate training in clinical informatics, applied health informatics and public health informatics. Such courses are already offered by Johns Hopkins but will now be expanded and many made available online beginning in fall 2010. The School of Medicine also offers a 12-month master of science degree in applied health sciences informatics, and a research informatics master of science program, which is completed in 24 months. The grant will offer tuition assistance to a limited number of these students.

Lehmann will oversee the training courses along with Nancy K. Roderer, director of the Division of Health Sciences Informatics and director of the Welch Medical Library. The Clinical Informatics Certificate, administered by the School of Medicine, takes six to eight months to complete. In the School of Nursing’s new eight-month certificate program in applied health informatics, students will earn 13.5 academic credit hours, which may then be applied toward a master’s degree. The Public Health Informatics Certificate program is run by the Bloomberg School’s Department of Health Policy and Management and is composed of six quarter-long courses, taken either for a certificate or as part of an existing degree program. Lehmann says that the academic informatics division at Johns Hopkins has worked for more than 10 years to create a full program of education for the informatics work force, ranging from innovative informatics research to leadership in design, implementation and deployment of health IT in clinical care and in public health. “This grant, building as it does on our existing activities, gives us a terrific opportunity to grow these efforts even further and to have Johns Hopkins play a major role in supporting the health IT landscape for Maryland and the mid-Atlantic region, as well as for public health nationally.” In a separate but related award, Abbott received a $1.8 million HITECH grant to develop a curriculum for health information technology work force development. “Despite mounting evidence that electronic health records have the power to transform health care, many hospitals, clinicians and others aren’t using them,” Abbott

the match already decided, the remaining rematches were halted. The Blue Jays are now 3-1 all-time in the Centennial Conference Tournament against the Garnet, including a 3-0 record in the title match. With the win, Hopkins earns the Centennial Conference’s automatic berth in the NCAA Tournament and will learn its postseason fate today with the announcement of the NCAA bracket. The magical day was capped off by the men’s tennis team, which bested visiting Swarthmore 6-0 in the Centennial Conference finals to win its fourth straight trophy and fifth in the last six years. The Blue Jays improved to 20-5 on the year, a new single season wins record. Hopkins swept the doubles matches to take a 3-0 lead on the hot and humid day in Baltimore. Sophomore Warren Elgort and junior Ryan Rauck gave the Blue Jays a 1-0 lead with an 8-4 win. Senior David Maldow and junior Andrew Wang then defeated their opponents 9-7. Sophomore Jacob Barnaby and junior Casey Blythe closed out doubles play with an 8-6 win. In singles play, Maldow dropped just three games in a 6-1, 6-2 win to push Hopkins’ lead to 4-0. Elgort and freshman Andy Hersh then claimed simultaneous wins to clinch the match. Hersh tied Wang and Blythe for most singles wins by a freshman in school history. The victory for Maldow, the winningest player in program history, was the 80th of his career. The men also earned an automatic berth to the NCAA Tournament. Tom Calder, director of Athletics, said that he was able to witness firsthand three out of the four titles, bopping from the baseball diamond to the tennis courts. “And I was in constant contact with the track coach. We were texting each other, and then I got the good news from him that we won,” Calder said. “I was also able to watch the women’s lacrosse team beat [No. 17–ranked] Ohio State on Homewood Field that same Sunday. It was a really, really good weekend.” Calder, who has been at the university for 21 years, called the day a rarity. “Four titles in four hours is special,” he said. “I’ll take four titles in one season.” G For more information on the Blue Jays’ postseason plans and upcoming schedule, go to

said. “The shortfall of HIT workers—approximately 50,000—is a major barrier to HIT adoption. Unfortunately, the country’s educational system is not currently prepared to train this desperately needed work force.” The School of Nursing’s new Curriculum Development Center is one of five centers that will develop a six- to 12-month informatics curriculum for deployment in U.S. community colleges. The aim is to give these colleges the ability to educate HIT workers, while helping college instructors supplement their own level of knowledge. The curriculum will be developed in collaboration with Johns Hopkins’ schools of Medicine, Public Health and Business, as well as four local community college partners. An advisory board will include academic HIT experts and representatives from HIT employer groups. “Anyone who takes these HIT courses in their local communities will have the benefit of a rigorous curriculum built by high-level university experts. Geography is irrelevant; no matter where the students are located, they will be able to access highquality training,” Abbott said. The two grants create a unique interdisciplinary team-centered approach to resolving work force shortages in HIT, Abbott said. “Collaborating on the Curriculum Development Center and the university-based training program at the same time will create a great HIT synergy here at Johns Hopkins,” she said. G Kelly Brooks-Staub of the School of Nursing and Gary Stephenson of Johns Hopkins Medicine contributed to this article.

May 10, 2010 • THE GAZETTE


Language of instruction not most important for English-learners By Beth Buckheit

School of Education


new study by researchers at Johns Hopkins University’s Center for Research and Reform in Education could change the way schools in the United States teach nonnative speakers to read and speak in English. The traditional argument surrounding the instruction of English-language learners has been whether English immersion or bilingual approaches work the best. But the Johns Hopkins study is poised to make that debate irrelevant: After five years studying Spanish-dominant children in six schools in California, Colorado, New Mexico, Minnesota, Illinois and Texas, the researchers found that the quality of instruction had a greater impact on how easily the children learned English than did the language of instruction. “There is considerable controversy among policy-makers, researchers and educators about how best to ensure the reading success of English-language learners,” said lead researcher Robert Slavin, director of the Center for Research and Reform in Education. “The goal of our study was to identify the appropriate role of native language in instruction.” Unique in that it follows children over a long period of time, the study was presented last week during the annual meeting of the American Educational Research Association in Denver. On May 1, Slavin was among 67 fellows inducted into the association. Funded by the Institute of Education Sciences at the U.S. Department of Education, the study tracked the reading and language performance of three cohorts of Englishlanguage learners who entered kindergarten in 2004, 2005 or 2006. Serving a range of impoverished neighborhoods in big cities and small towns, the schools studied were

almost entirely Hispanic, but two had significant African-American groups and one had 23 percent white, non-Hispanic students. The children studied were randomly assigned to either transitional bilingual education or structured English immersion conditions. During their kindergarten year, those in transitional bilingual classes were taught to read entirely in Spanish and then, by third grade, they transitioned to English reading instruction. In English immersion classes, all materials were in English, and teachers taught in English except for occasional Spanish explanations. To ensure that children in both conditions received consistent curriculum and instruction, Success for All—a reading program with parallel versions in Spanish and English—was provided to all students. Suc-

B y K at e r i n a P e s h e va

Johns Hopkins Medicine


esuscitation drills conducted during the first weeks of the H1N1 outbreak in May 2009 have exposed critical gaps in basic protection among hospital first-responders, according to a Johns Hopkins Children’s Center study. Failing to use personal protection such as gowns, glasses, respirator masks and gloves during infection outbreaks makes hospital staff vulnerable to infection and increases the risk for transmission to patients, the researchers say. The findings, presented May 4 at the Pediatric Academic Societies meeting, emphasize the need for repeat mock drills,


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materials in key areas and designating a “gatekeeper” to control access to the patient’s room and ensure that everyone is wearing protection—can go a long way toward improving performance. Teams that had a designated gatekeeper managed to start ventilation of the patient much faster (2.7 minutes) than teams that didn’t have one (4.7 minutes). The target time for initiating this lifesaving maneuver is less than one minute, the investigators say. In teams with assigned gatekeepers, all members used respirators, compared to 77 percent among teams without a gatekeeper. Co-authors on the study were Jordan Duval-Arnould, Michael McCrory, Stephan Froz, Trish Perl and Elizabeth Hunt.





n international consortium of scientists, led by researchers at The Johns Hopkins University, has identified two genes that when altered are closely associated with cleft lip and/or cleft palate. Cleft lip and cleft palate are among the world’s most common congenital malformations and occur in one in every 700 births. The finding is the result of the largest family-based, genomewide study of cleft lip and/or cleft palate conducted to date. The results were published online by the journal Nature Genetics. The study identified four different regions of the human genome likely to contain genes controlling risk for cleft lip and/or cleft palate. Two of these regions, the IRF6 gene on chromosome 1 and a region on chromosome 8, were previously identified in other studies. The current study identified genes MAFB on chromosome 20 and ABCA4 on another part of chromosome 1 as being associated with cleft lip and/or cleft palate. “We confirmed that the previously identified gene IRF6 and a suspected segment of chromosome 8 seem to be frequently altered in people born with clefts,” said Terri H. Beaty, lead author on the study and a professor of epidemiology at the Johns Hopkins Bloomberg School of Public Health. “This finding pulls together past work while identifying new potentially causal genes that help to move the science forward.” The genomewide association study involved 1,900 families with a baby affected with cleft lip and/or cleft palate from the United States, Norway, Denmark, the Philippines, Taiwan, China, Singapore and South Korea. More than 500,000 genetic markers

(called single nucleotide polymorphisms or SNPs) were used to cover the entire human genome. To test each marker, researchers compared these SNPs in babies affected with cleft lip and/or palate to those carried by his or her parents. The families studied were roughly evenly divided between families of European and Asian ancestry, allowing the two groups to be compared directly. The total sample identified four genes strongly associated with risk for cleft lip and/ or cleft palate. Families of European ancestry, including European-Americans, had the strongest statistical support for the region on chromosome 8; Asian families (from China, Korea, Singapore, Taiwan and the Philippines) had strongest support for IRF6, MAFB and ABCA4 genes. In addition to findings in humans, the investigators showed the MAFB gene was active in the developing head and mouth of embryonic mice, a finding which further argues that this gene plays some role in normal development. “While these findings cannot yet be used to identify infants or families at immediate risk, they do open up important new areas of biological research into the causes of cleft lip and palate,” Beaty said. “Fully understanding how several different genes can control risk to common human birth defects will create opportunities for more effective preventive measures in the future.” The consortium to study cleft lip and cleft palate was formed in 2007 and involved researchers at the Johns Hopkins Bloomberg School of Public Health, Johns Hopkins School of Medicine, University of Iowa, University of Pittsburgh and Utah State University, and groups from Norway, Denmark, the Philippines, Taiwan, China, Singapore and South Korea. The research was supported by the National Institutes of Health.

the researchers say, and suggest that personalprotection exercises should be included in monthly mock crisis sessions held at the Johns Hopkins Children’s Center. “Having another contagious outbreak is a matter of when, not if, and the time to master protection techniques is now, before it hits us,” said study lead investigator Christopher Watson, a pediatric critical-care fellow. The researchers conducted 11 drills on all inpatient units at the Johns Hopkins Children’s Center. The scenarios involved a pediatric patient infected with H1N1 experiencing a cardiopulmonary arrest. Of the 84 participants, only 51 used protective eyeglasses, while 73 used gowns and 68 used a special respirator mask. The mock drills showed that two simple measures—stacking carts with isolation


Bloomberg School of Public Health

Results of the study did not support the notion that native-language instruction in beginning reading rather than English immersion should ultimately help Spanishdominant children read better in English. Nor did the results support the superiority of English immersion. On the contrary, the study suggests that the language of instruction is not a key factor in the reading success of English-language learners. “Schools may choose to teach English-language learners in either their native language or in English for many reasons, including cultural, economic or political rationales, and either method can be successful if a quality instructional program is in place,” Slavin said. The full study is available on Johns Hopkins’ Best Evidence Encyclopedia Web site at www

H1N1 drills expose gaps in hospital infection protection

Genes associated with risk for oral cleft malformation identified By Tim Parsons

cess for All was developed by Slavin and has been extensively used and evaluated with Hispanic children. The current study did not evaluate Success for All but used it to provide consistent reading instruction. Slavin and his colleagues found that neither bilingual nor immersion programs offered a distinct advantage to students. On measures of Spanish language and reading, fourth-graders who had been taught to read in Spanish from kindergarten to second grade did not significantly outscore students taught only in English. And while English immersion students earned higher scores on reading tests in the early grades, there were few significant differences in their scores by fourth grade. Any advantages in either method’s favor diminished or disappeared by the fourth grade.


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105 West 39th St. • Baltimore, MD 21210 Managed by The Broadview at Roland Park

Notices Donations Needed for Druid Hill Family Center Y — Do you have new or gently

used toys or games that you can donate to the Druid Hill Family Center Y? Your donation of a wish list item will help the Y stretch its financial resources and provide healthy and enriching experiences for our community’s youth. For information about what kinds of items are appropriate, and for drop-off sites, call the Office of Work, Life and Engagement at 443-997-7000. For more information, go to http:// or call Work, Life and Engagement at 443997-7000. The Druid Hill revitalization effort is not eligible for Johns Hopkins Takes Time for Schools service hours. (For information regarding JHTTFS eligibility and program requirements, call Work, Life and Engagement.)

ESL Summer Intensive — Registration

is now open for the Intensive English Language Program, scheduled for July 6 through Aug. 6. Open to students and professionals


from Hopkins and around the world, the IELP offers language learners core reading, writing, listening and speaking classes at intermediate, advanced, and advanced plus levels, and electives in TOEFL preparation, medical English and American culture. Registrants may select the full program of three classes with 23 hours of language instruction, or the single class option. Social and recreational activities provide additional language practice. For Hopkins employees and postdocs, tuition remission may apply. For course descriptions and placement information, go to, e-mail esl@jhu .edu or call 410-516-5431. Development Workshop — A free

workshop titled “Your Research Career” is being offered this summer by the Professional Development Office. Aimed at JHMI students, graduate students and fellows, the workshop consists of five sessions, scheduled to take place from 9 a.m. to 12:30 p.m., from Monday, July 19, through Thursday, July 22, and from 9 a.m. to 4 p.m. on Friday, July 23. Registration is required. To sign up for any or all of the sessions, complete the registration form at www

How dark chocolate may guard against brain injury from stroke By Stephanie Desmon

Johns Hopkins Medicine


esearchers at Johns Hopkins have discovered that a compound in dark chocolate may protect the brain after a stroke by increasing cellular signals already known to shield nerve cells from damage. Ninety minutes after feeding mice a single modest dose of epicatechin, a compound found naturally in dark chocolate, the scientists induced an ischemic stroke by essentially cutting off blood supply to the animals’ brains. They found that the mice that had preventively ingested the epicatechin suffered significantly less brain damage than the ones that had not been given the compound. While most treatments against stroke in humans have to be given within a two- to three-hour time window to be effective, epicatechin appeared to limit further neuronal damage when given to mice 3.5 hours after a stroke. Given six hours after a stroke, however, the compound offered no protection to brain cells. Sylvain Doré, associate professor of anesthesiology and critical care medicine, and of pharmacology and molecular sciences, at the Johns Hopkins University School of Medicine, says that his study suggests that epicatechin stimulates two previously wellestablished pathways known to shield nerve cells in the brain from damage. When the stroke hits, the brain is ready to protect itself because these pathways—Nrf2 and heme oxygenase 1—are activated. In mice that selectively lacked activity in those pathways, the study found, epicatechin had no significant protective effect, and the mice’s brain cells died after a stroke. The study appears online in the Journal of Cerebral Blood Flow and Metabolism. Doré says that he hopes his research into these pathways could eventually lead to insights into limiting acute stroke damage and possibly protecting against chronic neurological degenerative conditions, such

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The Gazelle Group 410-343-3362

as Alzheimer’s disease and other age-related cognitive disorders. The amount of dark chocolate people would need to consume to benefit from its protective effects remains unclear, since Doré has not studied it in clinical trials. People shouldn’t take this research as a free pass to go out and consume large amounts of chocolate, which is high in calories and fat, he says. In fact, they should be reminded to eat a healthy diet with a variety of fruits and vegetables. Scientists have been intrigued by the potential health benefits of epicatechin by studying the Kuna Indians, a remote population living on islands off the coast of Panama who had a low incidence of cardiovascular disease. Scientists studying them found nothing striking in their genes and realized that when they moved away from Kuna, they were no longer protected from heart problems. Researchers soon discovered the reason was likely environmental: The residents of Kuna regularly drank a very bitter cocoa drink, with a consistency like molasses. The drink was high in the compound epicatechin, which is a flavanol, a flavanoid-related compound. Doré says that his research suggests the amount needed could be quite small because the suspected beneficial mechanism is indirect. “Epicatechin itself may not be shielding brain cells from free radical damage directly but instead, epicatechin, and its metabolites, may be prompting the cells to defend themselves,” he says. The epicatechin is needed to jump-start the protective pathway that is already present within the cells. “Even a small amount may be sufficient,” Doré says. Not all dark chocolates are created equal, he cautions. Some have more bioactive epicatechin than others. “The epicatechin found in dark chocolate is extremely sensitive to changes in heat and light,” he says. “In the process of making chocolate, you have to make sure you don’t destroy it. Only few chocolates have the active ingredient. The fact that it says ‘dark chocolate’ is not sufficient.” The new study was supported by grants from the National Institutes of Health and the American Heart and Stroke Association. Other Johns Hopkins researchers on the study are Zahoor A. Shah, Rung-chi Li, Abdullah S. Ahmad, Thomas W. Kensler and Shyam Biswal.

May 10, 2010 • THE GAZETTE

Classifieds APARTMENTS/HOUSES FOR RENT Bayview, 2-3BR apt, 1st flr. $700/mo + sec dep. 443-243-1651. Belvedere Square area, 2BR, 1.5BA upstairs apt, lg living rm, dining area, kitchen, powder rm, balcony, fp, hdwd flrs, 15 mins to JHMI, 10 mins to Homewood campus. $900/mo + utils. 410-435-6417 or Bolton Hill, 2BR luxury brownstone apt, deck, prkng pad, perfect for grad student/prof’l. 571933-3341. Butchers Hill, 2BR, 2.5BA carriage house apt, renov’d, lots of character, roof deck w/views. $1,825/mo incl prkng. Butchers Hill, bright, renov’d 2BR, 2.5BA house, 1/2 blk from Patterson Park, seconds to JHH/Canton/Fells Point/harbor. $1,600/mo + utils + sec dep. Marc, 443-452-8088. Butchers Hill/Canton, beautiful 2BR, 1BA TH, great location, conv to JHU; option to purchase. $985/mo. Tracy, 443-829-5038. Canton, 3BR, 2BA TH, no pets, avail June, refs req’d, 2 mi to JHH, $1,300/mo + utils + sec dep; also 3BR, 1BA TH in E Baltimore, $950/ mo + utils + sec dep. Anita, 410-675-5951 or Canton, gorgeous, remodeled 2BR, 2.5BA RH. $1,800/mo + utils. (for pics/info). Charles Village (32nd and Charles), sublet BR in 2BR, 1BA apt, avail June-August, nr Homewood campus. $635/mo. dea.molly.lovy@ Charles Village, spacious 3-story RH, hdwd flrs, W/D, 3rd-flr deck, rear yd, easy prkng, no smokers/no pets, short walk to 26th St shuttle. Charles Village, summer in the city, furn’d 1BR apt avail from mid-June to mid-August, new crpt, new appls, AC, W/D, WiFi. $865/mo. 410-236-9840. Charles Village, ground level 1BR apt 3 blks to Homewood campus, eat-in kitchen, W/D, backyd. $600/mo. 443-956-2616 or silkroadxx@ Charles Village (Charles St and University), 1BR studio, hdwd flrs, AC, storage unit, laundry, prkng, avail July 1. $750/mo. 443-5401540 or Charles Village (30th and Guilford), 4BR, 2.5BA RH, CAC, new windows, updated kitchen, yd, balcony, avail July 15 (or later). Kate, 410-235-6242. Eastwood (6904 Eastbrook Ave), beautiful, renov’d 2BR, 1.5BA house nr Bayview, avail July 1. $1,250/mo. 443-570-5492 or dave918@ Federal Hill, 3BR, 3.5BA rehab, lg kitchen, stainless steel appls, granite counters, dining rm, living rm, hdwd flrs, rooftop deck, CAC, W/D, security, courtyd. $1,990/mo. 443-824-4266. Fells Point, 3BR, 2.5BA RH, spacious kitchen, hdwd flrs, fin’d courtyd, walk to JHH/KKI/Fells Point/Harbor East. $1,900/mo. 410-718-6134. Hampden, historic 3BR, 1BA stone house, hdwd flrs, fps, yd, pets ok, available June 1. $1,650/mo. 410-599-4799. Hampden, 1.5BR TH, living rm, dining rm, kitchen, mud rm, hdwd flrs, AC, W/D, front porch, yd, off-street prkng. $890/mo + utils. 410-370-4555 or Hampden, 3BR, 2BA TH, dw, W/D, fenced yd, nr light rail. $1,100/mo + utils. 410-378-2393. Hopkins House, sublet furn’d studio apt, now to June 30. $600/mo. 443-794-3020 or 410948-7948.

Newly Remodeled HFR 4 Blocks to Bayview! 3BR, 1BA, parking pad, W/D $1800mo+util.



Jefferson Court, 2BR, 2.5BA TH, hdwd flrs, W/D, CAC, rear yd, off-street prkng incl’d, steps to medical campus. $1,100/mo + utils. 443-838-5575. Mt Vernon, sublet rm in 3BR apt, June 1 to end of August. $350/mo incl all utils, Internet. 425890-1327 or Mt Vernon, lg deluxe 1BR + den, entire flr in elegant bldg, marble fps, hdwd flrs, AC, sec sys, 2 blks to JHU shuttle, no smoking/no pets. $1,050/mo. 410-685-2347. Ocean City, Md (137th St), 3BR, 2BA condo on ocean block, lg pool, close to beach/restaurants/entertainment, 2 assigned prkng spaces. 410-544-2814. Owings Mills, 2BR, 2BA condo, backs to woods, W/D, walk-in closets, storage, prkng, conv to metro, nr grocery, sm pets negotiable ($250 nonrefundable deposit), 1-yr lease. $1,250/mo. 410-336-7952 or Station North (St Paul St), 300+ sq ft studio, historic, renov’d, secure bldg, nr food/fun/JHU shuttle/Bolt bus/Penn Station. $550/mo. 443471-6121, or http://userpages St Michaels, MD, cottage avail downtown for romantic, affordable wknd. Washington, DC, fantastic 3BR, 1.5BA house, AC, W/D, hdwd flrs, skylight, back deck, garage, conv to train/bus, nr Walter Reed Army Medical Center/Howard University Hospital. $1,7650/mo. Waterfront, 2BR cottage in Baltimore County, pier and boat slip, wraparound deck, W/D, dw, avail mid-June, conv to JHH/downtown/Bayview/JHU. $1,575/mo + utils + sec dep. 410790-6597 or (pics/details). Wyman Park, 3BR house, 1 blk to JHU, W/D, dw, security, cable, deck, prkng, fenced yd; Craigslist #1694651183 (photos). $1,650/mo + utils. Wyman Park, 3- to 4BR TH, 2 full BAs, CAC, W/D, dw, security, fenced yd, 1 blk to JHU. $1,500/mo + utils + sec dep. 410-493-4750 or Wyman Park, summer sublet 1BR apt, May 15-August 25 (shorter periods considered), sunny, quiet, walk to JHU, laundry facilities onsite, wireless Internet. 2BR, 1BA NE RH available. $1,000/mo. 917553-6461. 4BR, 2BA TH, avail June, 3 mins to Homewood campus. $1,600/mo + utils. 410-979-0721 or 1BR w/priv BA steps to medical campus, pref F nonsmoker. Beautiful 2BR apt at the Ambassador, spacious, great walk-in closets, avail June 23. $1,495/mo incl heat, water. 443-854-0498. 100 W University Pkwy, sublet avail, May 30-August 20, rent for the summer or just a month, above One World Cafe. $650/mo + utils. 251-751-8489.

HOUSES FOR SALE Arcadia/Beverly Hills (3019 Iona Rd), spacious, renov’d 4BR, 2.5BA detached house, lg open kitchen/dining area, landscaped, lg deck, beautiful neighborhood. $284,500. 443-803-1910. Cross Keys Village, renov’d 2BR, 1.5BA condo, sleek kitchen w/ceramic flr, granite counters, stainless steel appls, nr I-83, mins to JHH/JHU, nr shops/restaurants. $218,000. 443-742-3520. Guilford, 4BR, 2.5BA house w/remodeled kitchen, newly refin’d hdwd flrs, 2-car garage, 5-min walk to Homewood/JHH shuttle. $374,999. 443-798-8705 or Johns Hopkins / Hampden WYMAN COURT APTS. (BEECH AVE.) Effic from $570, 1 BD Apt. from $675, 2 BD from $775 HICKORY HEIGHTS APTS. (HICKORY AVE.) 2 BD units from $750 Shown by Appointment 410-764-7776

Mt Vernon, beautiful RH, 3 flrs, 1.5BA, priv backyd patio/garden, orig hdwd flrs, CAC/ heat. $229,000. 507-358-4194 or emilise@ Towson, 3BR house w/2 new BAs, new kitchen and appls, hdwd flrs, new siding/windows, fenced yd, flower garden, great schools, 20 mins to JHU. $270,000. 410-404-7355. Towson, 2BR, 2BA stone/siding house, lots of charm, stone fp, mins to JHU/JHH. $275,000 (rent option: $1,700/mo). smclaughlin333@ or Western Maryland, wknd house on 5-acre former horse farm.


Table w/shelves, printer, chair, tripods, 3-step ladder, digital piano, reciprocating saw. 410455-5858 or Schwinn 700C Trail Way hybrid bikes (2), men and women, 28", 24-spd, almost new, w/ trunk car rack, locks, helmets, tire pump. $380/ all. 410-336-5518 or Couch/loveseat, tan w/pillows, 4 yrs old; new glasstop dining table w/4 chairs; other misc household items. Queen-size Ikea bed, chest of drawers, nightstand, all cheap, can send pics. wreisig@ Evenflo carseat, 5-point harness, for kid up to 40 lbs, in good cond. $30. 410-377-6091 (after 6pm).

1BR and study in 2BR Canton RH, share w/M JHMI postdoc, 1st flr living rm, dining rm, eat-in kitchen, washer, window AC, 8 mins to Canton Square. $700/mo + utils. edandlora@

Lenox “Eternal” collection, 12 5-pc place settings, 6 wine glasses, 6 beverage glasses, oval vegetable bowl, never used, will sell whole lot or individual pcs, prices negotiable; red leather Michael Kors “Astor” handbag, tags attached, never used, $150.

Rm w/BA and patio in Fells Point, share w/2 grad students (1M and 1F). $700/mo incl utils, cable, wireless.

Baltimore Symphony tickets, 1 seat only for June 6, 3pm, orchestra center. $20/ea. 410444-1273.

Fully furn’d BR in lg Oakenshawe house, share BA w/other person, access to kitchen, owner has 2 cats, walk to Homewood campus/JHU shuttle, avail June 1-Sept 1. $470/mo incl water, elec. 410-800-3019.

iRobot Roomba 535 vacuum, gently used, excel cond, 6 mos left on warranty, unused accessories. $175/best offer.

Living rm in 2BR apt, private space separated from rest of apt by wood wall and curtain. $340/mo. 1BR and own BA in 2BR RH nr Patterson Park, share w/grad student, living rm, dining rm, W/D, storage. Share 2BR, 2BA apt in gated Pikesville community w/27-yr-old F prof’l/nonsmoker. $550/ mo + share of utils, cable, Internet. 443-8015363 or Share fully furn’d 3BR, 1.5BA RH in Ednor Gardens w/F SoM and SoN students, W/D, CAC, free cable/wireless, nr Homewood/JHMI shuttles. $535/mo + 1/3 utils. gmwang@gmail .com.

Orioles vs Nationals, tickets for June 25, lower reserved + fireworks. $15. 410-458-2878 or Moving sale: mattresses, microwave, futon, crpt, study tables, dining table, heater, bicycle, more.

SERVICES/ITEMS OFFERED OR WANTED Active, experienced nanny avail June 1, trained in CPR, will do household laundry, pet care, light housework, hrs flexible, outstanding JHU faculty references. Mary, 410-736-0253. Peabody classical guitar student seeking performance experience, will perform free for any event. 443-841-6198 or

1BR and priv BA in newly renov’d TH, share w/2 M grad students, sec sys, prkng, wonderful neighborhood. Paul, 410-979-0447.

Expert tutor: English, writing, essays, research papers, grammer, ESL, editor, thesis/dissertation. 240-882-6567 or


Mature, reliable couple looking to house-sit or sublet, good w/animals and plants, handy w/ household repairs/maintenance, nonsmokers, references, avail immediately. 410-733-1893 or

’00 Toyota Corolla VE, automatic, AC, great on gas, great maintenance, 130K mi. $4,000/ best offer. ’02 Nissan Altima, seascape green, in good cond, Md insp’d, 111.6K mi. $6,500/best offer. 410-484-1932 or ’04 Cobra, super clean, 65K mi; ask for list of upgrades and pics. $20,500. 703-926-0046 or ’00 Ford Focus, in good cond, 160K mi. $2,500. 410-793-4849. ’03 VW Jetta GLS, manual, 4-dr, leather seats, single owner, perf cond, 50K mi. $8,000/best offer.

ITEMS FOR SALE Sears professional treadmill, excel cond. $250. 410-522-7546. Chicco high chair, folding, adjustable height, reclining, removable tray, safety harness, excel cond. $30/best offer. 72" round, solid oak table w/4 chairs, can be refinished/painted. $100. 336-687-1758 or

Need a nanny? We have a great one and want to share her w/another 1- or 2-yr-old child starting this summer. 443-257-8858. Wanted: rm to rent in Remington/Charles Village area, W/D in bldg, easy walk to JHU shuttle. 410-262-4779. Dog walking and housesitting, your pets are family. 443-528-3637 or www.thankful-paws .com. Tutor wanted for SAT prep for high school student in Essex. 443-326-9036. Looking for PT dogsitter to come to my house, 11am-1pm, to walk our one-and-a-half-yr-old F lab/boxer mix, Mon-Fri, May 18 to June 12; call to discuss compensation. 410-340-2679 or Incoming MPH student seeks housesitting opportunity, I am an older prof’l and homeowner, will take same great care of your house as I do my own. Loving and trustworthy dog walker avail day and evening! Overnight sitting w/complimentary house-sitting services, impeccable references.

PLACING ADS Classified listings are a free service for current, full-time Hopkins faculty, staff and students only. Ads should adhere to these general guidelines: • One ad per person per week. A new request must be submitted for each issue. • Ads are limited to 20 words, including phone, fax and e-mail.

• We cannot use Johns Hopkins business phone numbers or e-mail addresses. • Submissions will be condensed at the editor’s discretion. • Deadline is at noon Monday, one week prior to the edition in which the ad is to be run. • Real estate listings may be offered only by a Hopkins-affiliated seller

not by Realtors or Agents. (Boxed ads in this section are paid advertisements.) Classified ads may be faxed to 443-287-9920; e-mailed in the body of a message (no attachments) to; or mailed to Gazette Classifieds, Suite 540, 901 S. Bond St., Baltimore, MD 21231.

12 THE GAZETTE • May 10, 2010 M A Y

1 0

1 7



“Genes, Networks and Disease,” a Biomedical Engineering special seminar with Joel Bader, WSE. 110 Clark. Wed., May 12, 4 p.m.

C OLLO Q U I A Wed.,



Crystallography, Computation and Single Molecular Fluorescence Transfer,” a Program in Molecular Biophysics seminar with studentinvited speaker Dorothee Kern, Brandeis University. Co-sponsored by Biophysics (KSAS) and Biophysics and Biophysical Chemistry (SoM). WBSB Auditorium. EB



“Chromatin and Today’s Housing Markets: Foreclosure, Remodeling and a Need for Regulation,” a Biology colloquium with Gregory Bowman, KSAS. 100 Mudd. HW

HW Wed., May 12, 4 p.m. “The Enzy-

Peabody Conservatory hosts a Beethoven ‘marathon’ today, May 10. Students of Leon Fleisher will perform all 32 of Beethoven’s piano sonatas, a process expected to take 12 hours. See Music.

Fri., May 14, 2 p.m. “Security, Protection and Compliance for Virtual Infrastructure (and the Cloud)—Building Security Into the Fabric,” an Applied Physics Laboratory colloquium with Michael Berman, Catbird. Parsons Auditorium. APL

C O N FERE N C E Wed., May 12, and Thurs., May 13, 9 a.m. to 6 p.m. “Spinoza

and German Idealism,” a Philosophy conference with various speakers. Great Hall and Glass Pavilion, Levering. HW I N FOR M AT I O N SESSIONS

Information session for the MS in Environmental Sciences and Policy Information program, a chance to learn about the program, meet the associate program chair, ask questions and submit an application. RSVP to rsvp/index.cfm?ContentID=2095. Sponsored by Advanced Academic Programs. Mason Hall. HW

Tues., May 11, 6:30 p.m.

The William M. Shelley Memorial Lecture—“Renal Neoplasia: Pathological Clinical and Molecular Correlates” by Victor Reuter, Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College, Cornell University. Hurd Hall. EB

Mon., May 10, 4 p.m. Dean’s Lecture IV—“Advances in the Prevention of HIV Transmission From Mother to Child” by Brooks Jackson, SoM. Sponsored by SoM. Hurd Hall. EB

The Second Homewood Brain and Cognition Lecture—“The Attentive Brain” with Steven Yantis, KSAS, and Earl Miller, MIT. Sponsored by Cognitive Science, Psychological and Brain Sciences, the Zanvyl Krieger Mind/Brain Institute and the Brain Sciences Institute. Mason Hall. HW

Thurs., May 13, 3 p.m.

The Sixth Annual Cancer Epidemiology, Prevention and Control Lecture—“Public Policy Development: The Collision of Cancer and Politics in Maryland” by Robert Villanueva, Maryland State Council on Cancer Control. Sponsored by Epidemiology. W3030 SPH. EB

Fri., May 14, 12:15 p.m.

The Vernon B. Mountcastle Lecture— “Signaling Networks That Regulate Synapse Development and

Fri., May 14, 4 p.m.

“From Expanding Marine Cloud Cover to Changing Hurricane Intensities: Aerosols Cloud-Mediated Climate Effects,” an Earth and Planetary Sciences special seminar with Daniel Rosenfeld, Institute of Earth Sciences. 305 Olin. HW

Thurs., May 13, noon.

“Genetic Manipulation and Next-Gen Sequencing to Dissect the Interactions Between Arboviruses and RNAi in Disease Vector Mosquitoes,” a Molecular Microbiology and Immunology/Infectious Diseases seminar with Zach Adelman, Virginia Tech. W1020 SPH. EB

Thurs., May 13, noon.

Cognitive Function” by Michael Greenberg, Harvard Medical School. Mountcastle Auditorium, PCTB. EB Mon., May 17, 5 p.m. The 2010 Efrem Potts Lecture—“Mysticism, Science and Moral Cosmopolitanism in Enlightenment Jewish Thought: The Book of the Covenant of Phinehas Elijah Hurwitz (1765–1821) and Its Legacy” by David Ruderman, University of Pennsylvania. Sponsored by Philosophy and the Leonard and Helen R. Stulman Jewish Studies Program. Smokler Center for Jewish Life (Hillel). HW

LE C TURE S Mon., May 10, 8:15 a.m.

matic Activity of Sirtuins: Beyond NAD-Dependent Deacetylation,” a Pharmacology and Molecular Sciences seminar with Hening Lin, Cornell University. West Lecture Hall (ground floor), WBSB. EB

MUSIC Mon., May 10, 10 a.m. to 10 p.m. Peabody Conservatory pres-

ents a Beethoven “marathon,” a performance of all of the composer’s piano sonatas. (See photo, this page.) Griswold Hall. Peabody Sun., May 16, 3 p.m. The Fran G. Zarubick Honors Recital, featuring the winners of the Preparatory Spring Honors Competition. Griswold Hall. Peabody

O P E N HOU S E S Sat., May 15, 2 to 4 p.m.

Open house for the Peabody Preparatory’s Adult and Continuing Education program; information, refreshments and tour. Bank of America Lounge. Peabody REA D I N G S Thurs., May 13, 7 p.m. Awardwinning author and current Gilman School writer-in-residence Josh Weil will discuss and sign copies of his novella collection, The New Valley. Barnes & Noble Johns Hopkins. HW

S E M I N AR S Mon., May 10, noon. “Environment, Epigenome and Human Health,” an Environmental Health Sciences faculty recruitment seminar with Wan-yee Tang,

University of Cincinnati College of Medicine. W2030 SPH. EB “Anticancer Drug-Induced Apoptosis: The View From Malignant Lymphoid Cells,” a Biochemistry and Molecular Biology seminar with Scott Kaufmann, Mayo Clinic. W1020 SPH. EB

Mon., May 10, noon.






“U.S. Assistance in Injury Prevention,” a Graduate Seminar in Injury Research and Policy with Nancy Carter-Foster, U.S. State Department. Sponsored by Health Policy and Management and the Center for Injury Research and Policy. W2033 SPH. EB Mon.,





“Thinking Like a Mountain: Incorporating Stories and Beauty in a Sustainable Bioethics,” a Berman Institute of Bioethics seminar with Peter Whitehouse, Case Western Reserve University. W3008 SPH. EB “Simulation and Investigation of Macromolecular Interactions by AUC: Drugs, Kinetics and Fluorescence Detection,” a Biophysics seminar with John Correia, University of Mississippi Medical Center. 111 Mergenthaler. HW

Mon., May 10, 4 p.m.

“Racial/ Ethnic Disparities in Children’s Early Social Emotional Development,” a Population, Family and Reproductive Health thesis defense seminar with Kamila Mistry. E4611 SPH. EB Tues., May 11, 10 a.m.

“Neurotrophic Signaling Promoted by Docosahexaenoic Acid,” a Biological Chemistry seminar with Hee-Yong Kim, NIAAA/NIH. 612 Physiology. EB

Tues., May 11, noon.






“Perinatal Mental Health: Associations Between Anxiety, Depression and Alcohol Use,” a Mental Health seminar with Julie Leis, SPH. B14B Hampton House. EB “The Choreography of a Protein’s Dance—Exploration by NMR,

Wed., May 12, 1:30 p.m.

Thurs., May 13, noon. “SuperResolution Microscopy: Introducing Ways to Cheat Physics and Strategically Preparing for a Shared Instrumentation Grant,” a Cell Biology seminar with Scot Kuo, SoM. Suite 2-200, 1830 Bldg. EB

“Sculpting Synaptic Weights: From Single Vesicles to Hippocampal Circuits,” a Neuroscience research seminar with Richard Tsien, Stanford University School of Medicine. West Lecture Hall (ground floor), WBSB. EB

Thurs., May 13, 1 p.m.

Thurs., May 13, 4 p.m. “Regeneration in Echinoderms: Cellular and Molecular Studies,” a Biology seminar with Jose Garcia-Arraras, University of Puerto Rico. 100 Mudd. HW

“Risk, Alcohol Drinking and Sexual Behavior Among Homosexual and Bisexual Men in the United States,” an Epidemiology thesis defense seminar with Hirut Gebrekristos. W2030 SPH. EB

Fri., May 14, 9 a.m.

Fri., May 14, 10 a.m. “Integrated Genomic Analyses of Human Pancreatic Cancer and Glioblastoma Multiforme,” a Pharmacology and Molecular Sciences thesis defense seminar with Xiaosong Zhang. 303 WBSB. EB

“Impact of Everyday Life Stresses on Reproductive Function: Mechanisms Underlying Stress Sensitivity,” a Biochemistry and Molecular Biology seminar with Judy Cameron, University of Pittsburgh. W1020 SPH. EB

“Transposons: Germline Invaders With a Lasting Impact on Genome Evolution,” a Carnegie Institution Embryology seminar with Cedric Feschotte, University of Texas, Arlington. Rose Auditorium, 3520 San Martin Drive. HW

“The Influence of Phosphate on Metal Homeostasis and Toxicity,” an Environmental Health Scences thesis defense seminar with Leah Scharf Rosenfeld. W7023 SPH.

Mon., May 17, 2 p.m.


The David Bodian Seminar—“Build­ ing Ex­pectations: New Vistas for Gamma Oscillations” with Sergio Neuenschwander, Max Planck Institute for Brain Research. Sponsored by the Krieger Mind/ Brain Institute. 338 Krieger.

Mon., May 17, 4 p.m.


S P E C I AL E V E N T S Mon., May 10, 9 a.m. to 1 p.m. Live Near Your Work Home

Ownership Expo, an opportunity to bring prospective home buyers together with area community representatives, homeowner’s associations and home-related businesses. Attendees may qualify for up to $17,000 toward the purchase of a home in designated areas of Baltimore City and enter to win prizes. Turner Concourse. EB Wed., May 12, 1 to 4 p.m. New Investigator’s Day and Research Honors moderated poster session with presentations by Hayley Mark, Shelly Eishbach and Marguerite Bay-Lucea. Sponsored by the Center for Nursing Research and the Center for Collaborative Intervention Research. Pinkard Building. EB Thurs., May 13, 5:30 to 8:30 p.m. Inaugural event for the

Center for Biotechnology Education with keynote speaker, Jesse Goodman, USFDA. (See story, p. 3.) Gilchrist Hall, Montgomery County Campus. SYMPOSIA Tues., May 11, 9:30 a.m. to 5 p.m. High Resolution Func-

tional Brain Imaging, a symposium in celebration of the 1,000th HRRT PET scan, and of local and international brain researchers employing high-resolution brain PET. The event features lectures and workshops, refreshments and a buffet lunch. Co-sponsored by Radiology and Radiological Science and the Brain Imaging Core of the Brain Sciences Institute. Tilghman Auditorium, Turner Bldg. EB

Mon., May 17, noon.






“Transport and Health Outcomes in Developing Countries,” a Graduate Seminar in Injury Research and Policy with Anthony Bliss, World Bank. Part of the International Injury series. W2033 SPH. EB Mon.,





Continued on page 7



(Events are free and open to the public except where indicated.)

APL Applied Physics Laboratory CSEB Computational Science and

Engineering Building

EB East Baltimore HW Homewood KSAS Krieger School of Arts and


PCTB Preclinical Teaching Building SoM School of Medicine SoN School of Nursing SPH School of Public Health WBSB Wood Basic Science Building WSE Whiting School of Engineering

The Gazette -- May 10, 2010  
The Gazette -- May 10, 2010  

The official newspaper of The Johns Hopkins University