20 18 16 14 12 10 8 6 4 2 0
<102 CFU/g aerobes may still open the door to Salmonella spp CFU/g and Escherichia102-105 coli contamination. >105 CFU/g Volatile fatty acids show up as from the first day of birds’ life and one of their main functions is to keep a balance among the naturally resident species in the Gastro-Intestinal Tract (GIT).
Van der Wielen et al (2000) have shown a correlation between un-dissociated butyrate, propionate and the control of pathogens in the Butyrate acid caecum of acid youngPropionic birds.
the natural production of butyric and propionic Effect on dietary Sodium Butyrate onAs caecal Salmonella colonization Moments of disbacteriosis – when a diet in broilers at day 8 (Van Immerseel et al., 2004) acid in the distal region of the GIT and caecum substrate, a contaminated environment or of young birds is too low and increases only until inadequate handling harms aerobes – propitiate the 15th day of life (van der Wielen et al., 2000) an unrestrained growth of aerobes giving rise to it is of the utmost importance to include in the a retro-contamination that may originate various feed formulation a reliable feed additive in the first enteritis including necrotic enteritis. stages of broilers’ life. The predominance of one or another species of 80 70 60 50 40 30 20
acetate lactate proprionate butyrate
10 0 -10
Ceacal VFA concentrations in broilers (in _mol/g content). Butyrate production in the caeca starts after 12-14 days of age.
Novyrate – Optimal solution that supports Gut Integrity