This paper is targeted on the improvement of the Nigeria 330kV 44Bus network voltage stability using ANN based adaptive STATCOM. The three-phase version of the test network was modelled in MATLAB-SIMULINK for simulations. Using the data obtained from the Transmission Company of Nigeria (TCN), Oshogbo and simulation data; ANN based adaptive STATCOM was developed, trained and deployed to the Test network for compensation of the weak section of the network. Results and analysis of simulations shows that the test network is unstable as the modal analysis revealed the presence of eigenvalue with a negative real part. Yola bus was discovered to be the most vulnerable bus with the highest participating factor and a voltage profile (of 0.83pu) less than acceptable lower limit of 0.95pu. The connection of ANN based adaptive STATCOM improved the stability of the network by enhancing the voltage profile of the network’s weakest bus by 22.9%. It was concluded that ANN based adaptive STATCOM was effective in improving t