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Dallas IFATS 2010 Scientific Program Day 1: Friday, October 22, 2010 7:00am-7:30am

Breakfast and Registration

7:30am-7:40am

Welcome and introductions: Spencer Brown, Peter Rubin, Michel Saint-Cyr

7:40am-7:50am

IFATS: History – Past & Future Ramon Llull

7:45am-8:00am

IFATS: Overview / History / Importance Spencer Brown, Peter Rubin SESSION I: BASIC SCIENCE Moderator: Spencer Brown, Paul DiMuzio

8:05am-8:10am

Opening remarks: Overarching Theme

8:10am-8:35am

Clegg, D SeXXy Fat

8:35am-8:50am

Sadek, H Metabolic Profiling of Stem Cells

8:45am-8:55am

Philips, B 100730074 Adipogenic and Proliferative Effects of Neuropeptide Y on Primary Cultured Human Adipose-Derived Stem Cells

8:55am-9:10am

Wolter, TP 100730049 Angiogenetic Growth Factor Production in Adipose TissueDerived Mesenchymal Cells

9:10am-9:25am

Lindroos, B 100705001 Differential Gene Expression In Human Adipose Stem Cells Cultured In Allogeneic Human Serum Versus Fetal Bovine Serum

9:25am-9:40am

Kazama, T 100730035 Dedifferentiated Fat (DFAT) Cells Convert Into Cardiomyocytes Phenotype And Repair Infarcted Cardiac Tissue In Rats With Myocardial Infarction

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9:40am-9:45am

DiMuzio, P 100729022 Flow Conditioning And Enos Transfection Improve Function of a Tissue-Engineered Vascular Graft (TEVG) Created with Adipose-Derived Stem Cells (ASC)

9:45am-9:50am

Brown, SA Isolated and Cultured Human Expression Profiles

9:50am-10:05am

Panel Discussion Break: 15 min SESSION II: DELIVERY SYSTEMS (SCAFFOLDING) Moderator: Adam Katz, Jae-Ho Jeong

10:20am-10:25am

Opening Remarks: Overarching Theme (Cell Biology)

10:25am-10:40am

Bourin, P 100730039 Submitted by Camille Duluc Evaluation Of A Defined Medium For The Culture Of Adipose-Derived Stromal Cells (Asc)

10:40am-10:55am

Miettinen, Susanna "Clinical use of ASCs in cranio-maxillofacial bone reconstruction".

10:55am-11:05am

Shang, H Have abstract Soft Tissue Engineering Using Modular, Serum-Free Methods

11:05am-11:15am

Lin, Sin-Daw 100729023 Listed as E-Paper accepted Hyaluronic Acid-based Scaffold for Growing Human Adipose-Derived Stem Cells in Immunodeficient Mice

11:15am-11:25am

Proulx, M 100729029 Tissue-Engineered Human Tissues as In Vitro Models for Prevascularized Substitutes: Impact of Adipocytes on the Formation of Capillary Networks

11:25am-11:35am

Orbay, H 100728012 Improving the Viability of Diced Cartilage Grafts: Effects of Adipose Derived Stem Cells and Slow-Release bFGF

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11:45am-11:55

Flynn, L 100728011 Soft Tissue Engineering with Decellularized Adipose Tissue

12:05pm-12:15pm

Lin, Yen-Chih  Adipogenesis of Human Adipose-Derived Stem Cells within 3D Hollow Fiber-Based Bioreactors

12:15pm-12:30am

Panel Discussion

12:30pm-1:30pm

LUNCH – POSTERS SESSION III: CLINICAL TRANSLATION Moderators: Keith March, Ali Mojallal

1:30pm-1:40pm

Opening Remarks: Overarching Theme (Cell Biology);

1:40pm-1:55pm

Butala, P 100730057 Augmentation of fat graft survival with progenitor cell mobilization in a murine model

1:55pm-2:10pm

Hanson, SE 100727010 Local delivery of adipose derived mesenchymal stem cells for cutaneous wound healing in a porcine model

2:10pm-2:25am

Hong, SJ 100801069 Intravenous Xenogeneic Transplantation of Human Adipose-Derived Stem Cells Improved Myocardial Function in Swine Acute Myocardial Infarction Model

2:25pm-2:30pm

Marra, K 100728014 ASC Survival Within a Novel, Biodegradable Polysaccharide Hydrogel for Adipose Tissue Engineering

2:30pm- 2:45pm

Lequeux, C Dermal equivalent using ASC

2:45pm-3:00pm

Bunnell, B Pronounced Anti-Inflammatory Effects of Adipose Stem Cells in the Central Nervous System

3:00pm-3:20pm

Panel Discussion

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SESSION IV: ASC – CLINICAL APPLICATIONS Moderators: Michel St-Cyr, Stuart Williams 3:20pm-3:25pm

Opening Remarks: Overarching Theme (Cell Biology)

3:20pm-3:45pm

Nolta, J Genetically Engineered Human Mesenchymal stem cells as development candidates for tissue repair and disease correction

3:45pm-4:00pm

McCarthy, RC 100729030 Biochemical Analysis of Crude Collagenase Products Used in Adipose Derived Stromal Cell (Adsc) Isolation Procedures and Development of a Purified Tissue Dissociation Enzyme (Tde) Mixture

4:00pm-4:15pm

Kono, T 100801071 Stem Cell Based Strategies to Enhance Pancreatic Islet Survival in Type 1 Diabetes Mellitus

4:15pm-4:30pm

Pellon, MAP 100730055 Cross-talk Between Subcutaneous Adipose Tissue and Skin & Utilization of Ischemic Adipocyte in the Healing of Burns

4:30m-4:45pm

Planat, V 10073044 Human ADSC Cell-Based Therapy For Skin Burn Wound Healing: Efficiency and Mechanisms

4:45pm-5:05pm

Panel Discussion

Day 2: Saturday, October 23, 2010 SESSION V: Clinical fat grafting: Innovation and Science behind Fat grafting supplemented with ASCs Moderator: Rod Rohrich, Peter Rubin 7:30am-7:40am

Opening Remarks:

7:45am-8:00am

Coleman, S 100730060 submitted by Robert Allen Density Fractions of Lipoaspirate: Implication in Fat Graft Survival

8:00am-8:15am

Canizares, O 100730059

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Comparison of the Fat Graft Survival Following Centrifugation

8:15am-8:30am

Hicok, K 100730032 Standardization of Analytical Methods for Autologous Human Fat Grafts

8:30am-8:45am

Doi, K 100727009 Stromal Vascular Fraction Isolation with an Automated System; Analysis of Cells and Clinical Use in Cell-Assisted Lipotransfer

8:45am-9:00am

Ould-Ali, D 100729027 Mechanical Factors Influencing Fat Cell Transplants Quality

9:00am-9:15am

Carvalho PP 100728021 Processing and Passaging of Human Adipose-derived Stromal/Stem Cells: Use of Animal Free Products and Extended Storage at Room Temperature

9:15am-9:30am

Maxwell, P Bioengineered Breasts: combining Implants, Scaffolds, and Cells

9:30am-9:50am

Panel Discussion Break: 15 min SESSION VI: Fat Grafting: Innovative Technology and role of stem cell supplementation Moderator: Rod Rohrich, Val Lampros

10:05am-10:10am

Opening Remarks

10:10am-10:25am

Coleman, S Reconstructive and Regenerative potential of fat grafting.

10:25am-10:40am

Lee, HY  Soft tissue volume augmentation with ASCs and scaffolds

10:40am-10:55am

Yoshimura, K Fat grafting with adipose stem cells; Stem cell grafting with dying tissue (signals)

10:55am-11:10am

DelVecchio, D 100714002

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Optimizing “Workflow” - Mega-Volume Fat Grafting Using the “Large Syringe” Technique

11:10am-11:25am

Saint-Cyr, M Fat Grafting Experience in Breast Reconstruction

11:25am-11:40am

Rubin, JP 100731068 Mammographic Changes after Stem Cell Supplemented Fat Transfer Compared with Changes after Breast Reduction

11:40am-11:55am

Khoobehi, K Fat Grafting for Implant Failure Patients

11:55am-12:20pm

Panel Discussion

12:20pm-2:30pm

LUNCH – EXHIBITS – POSTERS SESSION VII: Commercialization of ASC: Worldwide Perspective Moderators: Spencer Brown, Jan Nolta

2:40pm-2:45pm

Opening Remarks

2:40pm-3:00pm

Riordan, N - Medistem

3:00pm-3:20pm

Paspaliaris, B - Adistem

3:20pm-3:40pm

Cimino, W - GID Stem Center

3:40pm-4:00pm

Fan, Y - FDA representative FDA regulation of HCT/P (human cells, tissues and cellular or tissue-based products

4:00pm-4:25pm

Panel Discussion SESSION VIII: Military Applications of ASC: present and future needs Moderator: Peter Rubin, William Futrell

4:30pm-4:50pm

Col. Robert Hale, U.S. Army Institute of Surgical Research

4:55pm-5:05pm

Katz, A. Katz IFATS 2010 Adipose based therapies for military trauma

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5:05pm-5:15pm

Rubin, JP Adipose based therapies for military trauma

5:15pm-5:25pm

Panel Discussion

SESSION IX: Device & BioPharmaceutical Moderator: Spencer Brown, Rod Rohrich 5:30pm-5:35pm

Opening Remarks

5:35pm-6:00pm

Amaral, J - J&J Global commercial strategies for ASC

6:00pm-6:15pm

Panel Discussion

6:15pm-7:00pm

Cocktails with Vendors

Day 3: Sunday, October 24, 2010 SESSION X: Wound Healing Moderator: Adam Katz, Phillip Bourin 7:30am-7:40am

Opening Remarks

7:40am-7:50am

Coleman, S Improvement in Radiation Injury Following Fat Graft

7:50am-8:05am

Rifkin, L Effects of Fat Grafts and ASC in Radiation Rodent Model

8:05am-8:20am

LeBlanc AJ, Williams S 100730051 Adipose-Derived Stromal Vascular Fraction Patch Improves Coronary Blood Flow after Myocardial Infarct

8:20am-8:35am

Harman, RJ 100730031 Clinical Therapy of Adipose-derived Stem Cells in Dogs with Osteoarthritis and Rheumatoid-like Polyarthritis

8:35am-8:50am

Williams, S 100730050 Automated Point of Care Isolation of Adipose Derived Regenerative Cells for Tissue Engineered Vascular Grafts

8:50am-9:15am

Panel Discussion

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SESSION XI: Stem cells, Cancer and Late Breaking Presentations Moderator: Ali Mojallal, Katoro Yoshimura

9:20am-9:25am

Opening Remarks

9:25am-9:40am

Mojallal, A. Tumor Accelerated Growth in a Murine Model

9:40am-9:55am

Dominici, M 100731063 Gene-Modified Adipose Derived Progenitors as Anti-Cancer Therapy

9:55am-10:05am

Lamblet, H 100726007 Optimized autologous fat grafting with adipose derived stem cells within the operating room

10:05am-10:20am

Hitomi, E 100801070 Analyses of hematopoietic cells resident in human subcutaneous adipose tissue

10:20am-10:35am

Kelmendi-Doko, A  Adipogenic Factor-Loaded Microspheres to Augment Lipoaspirate for Soft Tissue Repair

10:35am-10:55am

Kato, H Adipose remodelling after non-vascularized grafting and therapeutic potential of systemic hyperoxgenation

10:55am-11:15am

Kim, MH Enhancement of myogenic differentiation of BEGF-treated adipose stem cell graft by using thermo sensitive hydrogel

11:15am-11:30am

Panel Discussion

11:30am-12:00noon

Meeting Summary IFATS/Business Meeting/Future Sites

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