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Dallas IFATS 2010 Scientific Program Day 1: Friday, October 22, 2010 7:00am-7:30am

Breakfast and Registration

7:30am-9:15am

Program

7:30am-7:45am

Welcome and introductions: Spencer Brown & Michel Saint-Cyr

7:45am-8:00am

IFATS: Overview / History / Importance. Ramon Llull SESSION I: BASIC SCIENCE Moderator: Spencer Brown, Paul DiMuzio

8:05am-8:10am

Opening remarks: Overarching Theme Electronic Questions

8:10am-8:35am

Deborah Clegg SeXXy Fat

8:35am-8:50am

Sadek, H TBA

8:45am-8:55am

Phillips, B Adipogenic and Proliferative Effects of Neuropeptide Y on Primary Cultured Human Adipose-Derived Stem Cells

8 :55am-9:10am

Wolter, TP Angiogenetic Growth Factor Production in Adipose TissueDerived Mesenchymal Cells

9:10am-9:25am

Lindroops, B Differential Gene Expression In Human Adipose Stem Cells Cultured In Allogeneic Human Serum Versus Fetal Bovine Serum

9:25am-9:40am

Matsumoto, T Dedifferentiated Fat (DFAT) Cells Convert Into Cardiomyocytes Phenotype And Repair Infarcted Cardiac Tissue In Rats With Myocardial Infarction

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9:40am-9:45am

DiMuzio, P Flow Conditioning And Enos Transfection Improve Function of a Tissue-Engineered Vascular Graft (TEVG) Created with Adipose-Derived Stem Cells (ASC)

9:45am-9:50am

Brown, SA Isolated and Cultured Human Expression Profiles

9:50am-10:10am

Panel Discussion & Electronic Answers Break: 20 min SESSION II: DELIVERY SYSTEMS (SCAFFOLDING,ETC.) Moderator: Adam Katz, tba

10:30am-10:40am

Opening Remarks: Overarching Theme (Cell Biology); Electronic Questions

10:40am-10:55am

Bourin, P Evaluation Of A Defined Medium For The Culture Of Adipose-Derived Stromal Cells (Asc)

10:55am-11:10am

Frohlich, M Bone grafts engineered from human adipose-derived stem cells in perfusion bioreactor culture.

11:10am-11:25am

Shang, H Soft Tissue Engineering Using Modular, Serum-Free Methods

11:25am-11:30am

Lin, Sin-Daw Hyaluronic Acid-based Scaffold for Growing Human Adipose-Derived Stem Cells in Immunodeficient Mice

11:30am-11:35am

Proulx, M Tissue-Engineered Human Tissues as In Vitro Models for Prevascularized Substitutes: Impact of Adipocytes on the Formation of Capillary Networks

11:35am-11:40am

Hakan, O Improving the Viability of Diced Cartilage Grafts: Effects of Adipose Derived Stem Cells and Slow-Release bFGF

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11:40am-12:00am

Panel Discussion & Electronic Answers

12:00pm-1:00pm

LUNCH – POSTERS SESSION III: CLINICAL TRANSLATION Moderator: Keith March, Ali Mojallal

1:30pm-1:40pm

Opening Remarks: Overarching Theme (Cell Biology); Electronic Questions

1:40pm-1:55pm

Butala, P Augmentation of fat graft survival with progenitor cell mobilization in a murine model

1:55pm-2:10pm

Hanson, SE Local delivery of adipose derived mesenchymal stem cells for cutaneous wound healing in a porcine model

2:10pm-2:25am

Hong, SJ Intravenous Xenogeneic Transplantation of Human Adipose-Derived Stem Cells Improved Myocardial Function in Swine Acute Myocardial Infarction Model

2:25pm-2:30pm

Marra, K ASC Survival Within a Novel, Biodegradable Polysaccharide Hydrogel for Adipose Tissue Engineering

2:30pm- 2:45pm

Lequeux, C Dermal equivalent using ASC

2:45pm-3:00pm

Bunnell, B TBA

3:00pm-3:20pm

Panel Discussion & Electronic Answers SESSION IV: ASC – CLINICAL APPLICATIONS

3:20pm-3:25pm

Opening Remarks: Overarching Theme (Cell Biology); Electronic Questions

3:20pm-3:45pm

Jan Nolta, Institute for Regenerative Cures, UC Davis

3:45pm-4:00pm

McCarthy, RC Biochemical Analysis of Crude Collagenase Products Used in Adipose Derived Stromal Cell (Adsc) Isolation Procedures

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and Development of a Purified Tissue Dissociation Enzyme (Tde) Mixture 4:00pm-4:15pm

Kono, T Stem Cell Based Strategies to Enhance Pancreatic Islet Survival in Type 1 Diabetes Mellitus

4:15pm-4:30pm

Pellon, MAP Cross-talk Between Subcutaneous Adipose Tissue and Skin & Utilization of Ischemic Adipocyte in the Healing of Burns

4:30m-4:45pm

Planat, V Human ADSC Cell-Based Therapy For Skin Burn Wound Healing: Efficiency and Mechanisms

4:45pm-5:05pm

Panel Discussion & Electronic Answers

Day 2: Saturday, October 23, 2010 SESSION V: Clinical fat grafting: Innovation and Science behind Fat grafting supplemented with ASCs Moderator: Rod Rohrich, Peter Rubin 7:30am-7:40am

Opening Remarks: Electronic Questions

7:45am-8:00am

Coleman, S Density Fractions of Lipoaspirate : Implication in Fat Graft Survival

8:00am-8:15am

Canizares, O Comparison of the Fat Graft Survival Following Centrifugation

8:15am-8:35am

Hicok, K Standardization of Analytical Methods for Autologous Human Fat Grafts

8:35am-8:50am

Doi, K Stromal Vascular Fraction Isolation with an Automated System; Analysis of Cells and Clinical Use in Cell-Assisted Lipotransfer

8:55am-9:10am

Jaffaroa, D Mechanical Factors Influencing Fat Cell Transplants Quality

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9:10am-9:25am

Carvalho PP, Gimble J Processing and Passaging of Human Adipose-derived Stromal/Stem Cells: Use of Animal Free Products and Extended Storage at Room Temperature

9:25am-9:40am

Maxwell, P Bioengineered Breasts: combining Implants, Scaffolds, and Cells

9:40am-10:00am

Panel Discussion & Electronic Answers Break: 15 min SESSION VI: Fat Grafting: Innovative Technology and role of stem cell supplementation Moderator: TBA

10:15am-10:20am

Opening Remarks & Electronic Questions

10:20am-10:35am

Coleman, S Reconstructive and Regenerative potential of fat grafting.

10:35am-10:50am

Lee, HY Soft tissue volume augmentation with ASCs and scaffolds

10:50am-11:05am

Yoshimura, K Fat grafting with adipose stem cells; Stem cell grafting with dying tissue (signals)

11:05am-11:20am

DelVecchio, D Optimizing “Workflow” - Mega-Volume Fat Grafting Using the “Large Syringe” Technique

11:20am-11:35am

Cohen, S Fat Grafting Experience with Stem Cells

11:35am-11:50am

Rubin, JP Mammographic Changes after Stem Cell Supplemented Fat Transfer Compared with Changes after Breast Reduction

11:50am-12:10am

Panel Discussion & Electronic Answers

12:10pm-1:30pm

LUNCH – EXHIBITS – POSTERS

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1:30pm-3:25pm

Commercialization of ASC: Worldwide Perspective

1:40pm-2:00pm

Neil Riordan, Medistem

2:00pm-2:20pm

Bill Paspaliaris, Adistem

2:20pm-2:40pm

Ramon Llull, GID Stem Center

2:40pm-3:00pm

Yong Fan, FDA representative

3:00pm-3:25pm

Panel Discussion & Electronic Answers SESSION VII: Military Applications of ASC: present and future needs Moderator: Spencer Brown, TBA

3:30pm-3:50pm

Col. Robert Hale, USAF

3:55pm-4:05pm

Katz, A. Autologous fat transfer for scar prevention [late]

4:05pm-4:15pm

Rubin, JP ASC in Wound Healing

4:15pm-4:35pm

Panel Discussion & Electronic Answers SESSION VIII: Device & BioPharmaceutical Moderator: TBA

4:40pm-4:10pm

Opening Remarks & Electronic Questions

4:10pm-4:40pm

Joe Amaral. J&J Global commercial strategies for ASC

4:40pm-5:00pm

Panel Discussion & Electronic Answers

5:15pm-7:00pm

Cocktails with Vendors

Day 3: Sunday, October 24, 2010 SESSION IX: Wound Healing Moderator: Ramon Llull, TBA 7:30am-7:40am

Opening Remarks & Electronic Questions

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7:40am-7:50am

Lee, Coleman S Improvement in Radiation Injury Following Fat Graft

7:50am-8:05am

Brown S Effects of Fat Grafts and ASC in Radiation Rodent Model

8:05am-8:20am

Lindroos, B Long Term Follow-up of Clinical Mandibular Regeneration

8:20am-8:25am

LeBlanc AJ, Williams S Adipose-Derived Stromal Vascular Fraction Patch Improves Coronary Blood Flow after Myocardial Infarct

8:25am-8:30am

Harmon RJ Clinical Therapy of Adipose-derived Stem Cells in Dogs with Osteoarthritis and Rheumatoid-like Polyarthritis (Vetstem)

8:30am-8:50am

Panel Discussion & Electronic Answers SESSION X: Stem cells and Cancer: What is going on? Moderator: Ali Mojallal, TBA

9:15am-9:25am

Opening Remarks & Electronic Questions

9:25am-9:40am

Mojallal, A. Tumor Accelerated Growth in a Murine Model

9:40am-9:55am

Dominici, M Gene-Modified Adipose Derived Progenitors as Anti-Cancer Therapy

9:55am-10:10am

Lamblet, H Optimized autologous fat grafting with adipose derived stem cells within the operating room

10:10am-10:25am

Hitomi, E Analyses of hematopoietic cells resident in human subcutaneous adipose tissue

10:25am-10:40am

Jeong, S Therapeutic Potential Of ASC In Allogenic Transplantation on a Rat Hindleg Model

10:40am-11:00am

Panel Discussion & Electronic Answers

7


11:00am-12:00noon

Meeting Summary IFATS/Business Meeting/Future Sites

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iFats Dallas 2010 Program