Page 34

LSS Urinary System 352 352

352 390

Alexandra Burke-Smith 240 390

And again, we get this, Descending 290 318 343 374

Interstitium 318 343 374 421

Ascending 159 197 290 421

And yet again, we get this, Descending 290 314 344 388

Interstitium 314 344 388 448

Ascending 170 232 321 448

Thus, if we go around the cycle 4 times, this is what we end up with. Note that while we started with the same osmolarity everywhere we have finished with (a) Interstitial osmolarity near the bend of the loop well above the starting value of 290 mosomol/l – i.e. HYPERTONIC (b) Osmolarity in the fluid emerging from the loop of Henle well below 290 mosmol/l – i.e. HYPOTONIC Descending Interstitium Ascending 290 214 170 314 344 232 344 388 321 388 488 448 This is obviously a very simplified model of the loop of Henle. We can complicate it further by considering 50 horizontal levels in the loop (instead of 4) and by going round the cycle 100 times (instead of 4). This graph shows the calculated values of the interstitial osmolarity at 50 different levels after 100 cycles. 34

Alex's Urinary  

Alex's Urinary

Advertisement