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Recerca: Control de la potència de les cèl·lules mare | 35

iPSC humanes agregades per formar cossos embrioides

Projectes de recerca n CELLSCAFF-CARTILAGE In situ tissue engineering using stem cells and functional biomaterials to repair articular cartilage: An ‘in vivo model’ (2009-2012) IP: Ángel Raya MICINN, FCCI-ACI-E

Human pluripotent stem cells and zebrafish heart regeneration as experimental tools to understand cardiac muscle cell differentiation (2009-2012) IP: Ángel Raya MICINN, Investigación fundamental no orientada. n

n Generación de un modelo neuronal dopaminérgico a partir de células madre pluripotentes inducidas de pacientes con enfermedad de Parkinson asociada a mutaciones en el gen LRRK2 IP: Ángel Raya ISCII; Convocatoria de financiación interna para proyectos cooperativos de CIBERNED n HEMO-iPS Use of patient-specific induced pluripotent stem cells to improve diagnosis and treatment of Hemophilia A IP: Ángel Raya ISCIII; E-Rare JTC 2011

CELLSCAFF-CART Reparación de Cartílago Articular mediante Ingenieria de Tejidos in situ: modelo in vivo (iPSC) IP: Ángel Raya MICINN; Fomento de la cooperación científica internacional (FCCI) ACI-Promociona n

n Zebrafish heart regeneration and human pluripotent stem cells as models to understand human cardiac muscle cell differentiation IP: Ángel Raya EMBO

Publicacions Sánchez-Danés, A., Richaud-Patin, Y., CarballoCarbajal, I., Jiménez-Delgado, S., Caig, C., Mora, S., Di Guglielmo, C., Ezquerra, M., Patel, B., Giralt, A., Canals, J.M., Memo, M., Alberch, J., López-Barneo, J., Vila, M., Cuervo, A.M., Tolosa, E., Consiglio, A. & Raya, Á. (2012). Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson’s disease. EMBO Molecular Medicine, 4 (5), 380-395

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Futterer, A., Raya, Á., Llorente, M., Izpisua-Belmonte, J.C., de la Pompa, J.L., Klatt, P. & Martinez, A.C. (2012). Ablation of Dido3 compromises lineage commitment of stem cells in vitro and during early embryonic development. Cell Death and Differentiation, 19 (1), 132-143

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McLenachan, S., Menchon, C., Raya, Á., Consiglio, A. & Edel, M.J. (2012). Cyclin A(1) is essential for setting the pluripotent state and reducing tumorigenicity of induced pluripotent stem cells. Stem Cells and Development, 21 (15), 2891-2899

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Profile for IBEC

Memòria IBEC 2012  

Memòria 2012, Institut de bioenginyeria de Catalunya (IBEC)

Memòria IBEC 2012  

Memòria 2012, Institut de bioenginyeria de Catalunya (IBEC)

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