▲ existing building
@4240 Laboratory and Office Building
St. Louis, Missouri, USA
Completion: 2014 Annual EUI: 124 kBTU / sf / yr
This adaptive reuse project anchors the Cortex
Large floor plates and highly adaptable
Relocating the building’s main entry promotes
Innovation Community, a 200-acre mixed-use
mechanical systems enable @4240 to
interaction with the newly planned Cortex
urban research district in midtown St. Louis.
support a variety of tenants, from small
Commons, a park-like green space that serves
startups to larger, more established research
as the district’s community hub.
Originally constructed in 1948 as a telephone
organizations. The space includes fully
handset factory, the three-story building was
equipped conference rooms, open meeting
Located within walking distance of a planned
redeveloped by Wexford Science & Technology
areas, green spaces, cafés and casual
public transit station, the building is near
to provide flexible laboratory and office space
Barnes-Jewish Hospital, Washington
for tenants involved in life sciences, research, technology, innovation and entrepreneurship.
University School of Medicine and Saint Louis The LEED Platinum-certified project features
University. This location provides convenient
extensive use of renewable building materials
access to additional scientific resources and
Preserving and highlighting the masonry
and energy-efficient measures, including a
structure’s historic character, the design
50-kV photovoltaic array.
team retrofitted the building with modern, high-performance systems that enable it
The design and construction team worked
to function as a state-of-the-art research
within historic guidelines to restore the
and office facility. Floor openings cut into
building’s deteriorating brick facade, add
the middle of the building allow skylights
insulation under a new roof and upgrade the
to illuminate a courtyard, light wells, the
industrial windows with historically accurate,
building’s interior and a two-story concourse.
insulated replacement glazing. The building
By creating informal meeting and collaboration
is 45 percent more energy efficient than a
areas, the concourse functions as a “mixing
typical lab and office facility.
space” for the complex.
◄ central concourse level 1
2016 design annual
183,000 sq. ft. / 17,000 sq. m.