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HOK B I O M E D I C A L + T R A N S L AT I O N A L H E A LT H FA C I L I T I E S

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“We interviewed many experienced firms for the IRC (now WIMR) project. In the end, we selected HOK because we were not only impressed with the firm’s breadth of experience, but also with the team’s personal approach to project delivery. We have not been disappointed.” - Mr. Mark Wells Assistant Dean of Facilities University of Wisconsin - Madison


B I O M E D I C A L + T R A N S L AT I O N A L H E A LT H FA C I L I T I E S A S A M P L E O F O U R P R O J E C T S F O C U S E D O N T R A N S L AT I O N A L A N D BIOMEDICAL RESEARCH

W IM R

CEDA RS

CRICK

TCMC

OS U

University of Wisconsin, Wisconsin Institutes for Medical Research

Cedars-Sinai Medical Center, Advanced Health Sciences Pavilion

The Francis Crick Institute

The Commonwealth Medical College

The Ohio State University Med. Ctr. Cancer Hospital and Critical Care Tower

UMB

EM O RY

U. F LO RIDA

U. B U F FA LO

RIM ED

University of Maryland, Baltimore Health Sciences Facility III

Emory Univ. Whitehead Biomedical Research Building

University of Florida, Lake Nona Academic and Research Center

University at Buffalo School of Medicine and Biomedical Sciences

Fondazione RiMED Biomedical Research & Biotechnology Center hok .com


HOK

HOK is a global provider of planning, design and delivery solutions for the built environment.

Since the firm’s founding in 1955, HOK has developed into one of the world’s largest, most diverse and respected design practices. The firm employs more than 1,600 professionals linked across a global network of 24 offices on three continents. hok .com


HOK SCIENCE + TECHNOLOGY

In response to the growing need to fully service the unique organizational and scientific challenges facing our clients in science and technology organizations, the HOK Science + Technology group was born.

This group of expert professionals brings innovative facility design to our most complex projects around the world.

hok .com


KING ABDULL AH UNIVERSIT Y OF S C I E N C E A N D T E C H N O L O GY

LEED PLATINUM Certification


S U S TA I N A B L E D E S I G N

HOK has become one of the world’s preeminent sustainable design experts and many of our projects have received LEED Certification.

We have made the commitment to design facilities from the whole building perspective.

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The new model of health sciences is changing from a focus on treatment of

models to fruition for academic

disease to a focus on health.

medical centers.

The increasing convergence

Present day function and future

of knowledge and capability at

exibility that allow for growth and

the most fundamental level of

renewal are the tip of the iceberg.

biological sciences and systems

Evolving trends in medicine and

requires moving away from

treatment, including translational

reparative medicine and nursing

medicine, genomic medicine and

to a new model of predictive and

research, proteomics, and evolving

proactive public health.

patient-centered care models are shaping today’s academic medical

An interdisciplinary model for

centers.

education, research, and the practice of medicine is at the

Environments for academic

forefront of design for health

medical research and education

sciences.

must be ready to accommodate tomorrow’s innovation. HOK

HOK develops innovative design

designs buildings that maximize

solutions which create aligned

opportunities for researchers and

vision and bring translational

physicians to share knowledge.


T R A N S L AT I O N A L R E S E A R C H FAC I L I T I E S

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T R A N S L AT I O N A L R E S E A R C H FAC I L I T I E S

If the goal of academic medical centers engaged in translational research is

application of new technologies

creating novel, basic scientiďŹ c

for the patient-driven environment,

discoveries that translate

including early patient testing and

into clinical applications, then

evaluation using traditional and

collaboration, technology and its

genomic techniques.

critical infrastructure are what enables development of bench-to-

By building partnerships

bedside therapies.

that facilitate the interaction between basic research and

The design of these facilities

both clinical medicine and clinical

must enhance the communication

trials, innovation can ourish

link between research scientists

because information can ow

and physicians vital to cutting-

freely between researchers and

edge research that connects

clinicians. Many major medical

basic research to patient care.

centers are looking to of predictive

Translational techniques are

medicine to identify biological

a core competency central to

markers to identify individuals

comprehensive cancer care,

at high risk for developing

emphasizing the bench-to- bedside

diseases using techniques such

potential. Facility design must

as genomics, proteomics, and

enable the development and

cytomics.


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SIZE

469,000 sq. ft. COMPLETION

2008


UNIVERSIT Y OF WISCONSIN, WISCONSIN INSTITUTES FOR MEDICAL RESE ARCH

Madison, Wisconsin

The new Wisconsin Institutes for Medical Research (WIMR) is the centerpiece of the Medical School’s efforts at creating the world’s preeminent cancer research institute. The seven-story East Tower is the first of WIMR’s three planned interdisciplinary research towers to house researchers in highly interactive spaces designed to cultivate collaboration.

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UW researchers from a wide range of backgrounds occupy the WIMR, working together to study the underlying mechanisms of cancer, identifying potential treatments and cures then rapidly translating their discoveries into promising new therapies for patients at the adjacent clinic/hospital. Adjacent to UW Hospitals and Clinics, WIMR scientists can easily interact with clinicians and are within sight of the patients whose lives they hope to improve. The East Tower, eliminates laboratory walls, places office areas close to labs, allows rapid sharing of complex equipment and facilities and includes interaction space on every floor. Alternate floors are also joined by twostory atriums to further enhance communication and collaboration. The Advanced Imaging and Radiation center, with walls and


UNIVERSIT Y OF WISCONSIN

ceilings more than eight feet thick, is designed to be vibrationfree. Equipment includes every imaging modality for human and animal research at the molecular level as well as a 30-ton cyclotron for production of short-lived imaging agents and computerized chemical synthesis. Complete facilities are provided for the development of state-of-theart, three-dimensional radiation oncology application development. The first floor and basement also house one of the nation’s largest rodent and primate vivaria. Lab floors are organized to support the multi-disciplinary approach to research, so that all parties involved in a specific research area are located on the same floor. Teams that require additional space can overflow onto another floor via the twostory atria without losing the ability to interact. hok .com


SIZE

820,000 sq. ft. COMPLETION

2013

4 LEED GOLD


CEDA RS-SIN AI M EDICA LCEN T ER A D VA N C E D H E A LT H S C I E N C E S P AV I L I O N

Los Angeles, California

Cedars-Sinai is dedicated to providing the best possible care for its patients.

HOK guided project planners at Cedars to realize the path to profound change in their organization would come through a translational facility that would combine patient care, clinical offices, research, physician education and training.

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Utilizing an incredibly flexible model, the facility was planned and designed to provide outpatient procedure services in Cardiac Care and Neuroscience. Attracting and retaining the “triple-threat� physicians (educator/researcher/physician) is a primary mission of Cedars-Sinai. The facility provides for procedure suites, clinic/office space, and research facilities, as well as a training center with a simulation center and debrief rooms. Every doctor who is assigned to this facility will be an active researcher and practicing physician, and


CEDA RS-SIN AI M EDICA LCEN T ER

will be able to directly apply their research into highly personalized patient care. A connected link to the main hospital facility will allow for inpatients to benefit from procedures in the state-of-theart procedure suites, and be transferred back to their rooms in the hospital. The building will also house a fully functioning pharmacy, Imaging center (including MRI and CT), and a centralized conferencing facility to allow for maximum interaction of physicians.

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SIZE

THE FR ANCIS CRICK INSTITUTE

635,000 sq. ft.

London, United Kingdom

COMPLETION

2014

HOK designed what will become one of the world’s major research centers, covering research in a broad range of biomedical sciences including translational research.

Six leading UK research organizations have come together to build this hub for research into the development, prevention and treatment of significant diseases.

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HOK designed what will become one of the world’s major research centers, covering research in a broad range of biomedical sciences including translational research. Six leading research organizations - The Medical Research Council, Cancer Research UK, The Wellcome Trust, UCL (University College London), Imperial College London and King’s College London - have come together to build the Francis Crick Institute: the hub for research into the development, prevention and treatment of diseases such as cancer, heart disease/stroke, infections, and neurodegenerative diseases. The laboratories are arranged over four floors, with each floor consisting of four interconnected blocks which will bring together staff working in different fields.


THE FR ANCIS CRICK INSTITUTE

The laboratories are designed to be adaptable to change as new scientific opportunities emerge in the future. This facility will support highly translational research as it is equipped with high-performance IT infrastructure for virtual collaboration, integrated analysis and bedside decision support as well as a state-of-the-art imaging center to further promote human subject translational research. More than 7,500 sq. ft. of biocontainment space (at BSL-3 or higher) will allow for world-leading research into diseases such as influenza, malaria, tuberculosis and HIV. A state-of-the-art, 85,000 sq. ft. barrier research facility includes: SPF (Specific Pathogen Free), EXP (Experimental Barrier), BSL3, UHS (Unknown Health Status), Aquatics and Imaging. hok .com


SIZE

194,263 sq. ft. COMPLETION

2011


T H E C O M M O N W E A LT H M E D I C A L C O L L E G E

Scranton, Pennsylvania

HOK worked with The Commonwealth Medical College to create their vision of a freestanding medical school with no university affiliation. Within this independent structure, TCMC is able to partner with health science programs throughout the region, offering students a variety of educational experiences; preparing them to become community physicians practiced in evidence-based medicine. hok .com


The west research wing and east educational wing surrounds a shared courtyard. The linkage between the two buildings acts as the central hub where students can gather and socialize at the grand porch, courtyard and cafĂŠ. To the east, public ground floor spaces include additional student common areas, a bookstore and lobby for the 250 seat auditorium. The Research space is 63,929 square feet and can support 16 Principal Investigators (PIs) for wet research and 4 PIs for bioinformatics. In 35 laboratories, researchers can focus on diseases that are relevant to the area, including issues with aging as well as cancers of the colon, breast and lung. The state of the art flexible labs, stairways and common areas offer ample daylight and promote interaction and collaboration. A 5,000 sq.


T H E C O M M O N W E A LT H M E D I C A L C O L L E G E

ft. vivarium and cagewash, as well as imaging facilities, support biomedical research for students and faculty. The ground floor of the north structure contains a simulation facility with 12 mock exam rooms for standardized patients (actors portraying patients) and several suites for simulated surgical procedures using high-fidelity robotics, as well as breakout rooms and small group work areas. The gross anatomy lab is also included in this area. All simulation spaces offer high definition video for real time viewing by professors or other students, or for later review. The new buildings incorporate principals of sustainable development and should garner the facility LEED Certification.

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SIZE

1,100,000 sq. ft. COMPLETION

2014


T H E O H I O S TAT E U N I V E R S I T Y M E D I C A L C E N T E R , J A M E S C A N C E R H O S P I TA L A N D CRITICAL CARE TOWER

Columbus, Ohio

As part of the University Medical Center’s South Campus Master Plan Implementation this project includes growth and replacement of the Arthur G. James Cancer Hospital and associated translational research facilities, critical care beds, surgery and imaging to create The Ohio State’s Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute.

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SIZE

198,000 sq. ft. COMPLETION

2009

4 L E E D - N C S I LV E R


UNIVERSIT Y OF CENTR AL FLORIDA SCHOOL OF BIOMEDICAL SCIENCE

Orlando, Florida

Providing quality undergraduate and graduate programs in the biomedical sciences to build robust research programs focused on cancer and cardiovascular, neurological, and infectious diseases is the mission of the Burnett School of Biomedical Sciences.

HOK’s design creates the cornerstone facility of the new research quadrant.

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As envisioned in HOK’s campus masterplan, this facility is the first of several buildings that will ultimately create a biomedical cluster; providing UCF with key health partnerships to allow for the rapid translation of laboratory findings into new patient cures. The School is committed to its role in developing technology-based industry in Florida.Innovative partnerships formed with the College of Optics and Photonics and the NanoScience Technology Center facilitate interdisciplinary research and education programs in the application of photonics, bioinformatics and nanoscience to biomedical problems. HOK designed this facility to “(HOK are) the first architects I have worked with that listened to our issues, and responded with contemporary and cost effective solutions.” Robert N. Gennaro, PhD Burnett College of Biomedical Sciences

support the new undergraduate curriculum in biomedical sciences; updated to better prepare students for admission to medical/ health profession schools


UNIVERSIT Y OF CENTR AL FLORIDA

and graduate programs in the biomedical sciences. The research center includes four levels of labs and investigator offices, specialty core support labs, a transgenic animal facility (vivarium), faculty offices and administrative suite. Core lab areas include space for two Electron Microscopes, two Confocal Microscopes and associated image processing; large x-ray crystallography suite; multiple rooms for light and fluorescence microscopy, as well as conventional dark rooms. Containment space is an enhanced BSL-3, with HEPA filtration of all exhaust air, and shower-out ability. HOK worked closely with UCF to include sustainable features such as FSC Certified lab casework and wood materials; as well as energy recovery on general lab exhaust. hok .com


SIZE

325,000 sq. ft. COMPLETION

2001 4 L E E D S I LV E R


EMORY UNIVERSIT Y W H I T E H E A D B I O M E D I C A L R ES E A R C H B U I L D I N G

Atlanta, Georgia

This eight-story interdisciplinary biomedical research facility for genetics, cell biology, physiology and neuroscience research includes special facilities such as animal housing, tissue culture, and environmental health and safety support facilities. It supports BSL-2 and BSL-3 research activities.

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SIZE

330,000 sq. ft. COMPLETION

2017


U N I V E R S I T Y O F M A R Y L A N D , B A LT I M O R E H E A LT H S C I E N C E S F A C I L I T Y 3

Baltimore, Maryland

This new facility for the University’s Medicine, Dentistry and Pharmacy Schools is the third phase of the Health Science Facility at UMB, and is expected to help advance UMB’s position as academic research leaders, and to recruit the best faculty, students and staff. The building is sited among the three schools’ existing facilities to maximize interactions and the sharing of resources. hok .com


SIZE

100,000 sq. ft. COMPLETION

2012 4 L E E D P L AT I N U M


UNIVERSIT Y OF FLORIDA ACADEMIC AND R E S E A R C H C E N T E R AT L A K E N O N A

Orlando, Florida

This new academic and research facility will complement the Lake Nona “Medical City� institutions. The UF College of Pharmacy, including the newly established pharmacometrics and systems pharmacology initiative in the interdisciplinary Institute of Therapeutic Innovation, will relocate its Orlando campus to this vibrant new building.

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Sited on approximately five acres “All of the HOK team have been extremely responsive to the needs of the faculty and the Lake Nona development. We have been impressed with their BIM capabilities, their team approach with the Construction Manager and the willingness to meet the goals of UF for a minimum Gold LEED building.� Carol J. Walker, Assistant Vice President UF Facilities Planning & Construction

directly adjacent to the Sanford Burnham Institute, the new center takes a dramatic form to represent the innovative, collaborative and life changing activities housed inside. The research areas include two floors of open laboratories consisting of large, ballroom plan island bench areas with mobile sinks and casework, supported by fume hood and BSC alcoves and other support functions at either side, and are located to maximize the views of the wooded preserve to the south. A glass wall along the inboard side of the research laboratories provides a visual connection to the office zone for faculty and graduate students. One floor is devoted specifically to research conducted in enhanced environments.


UNIVERSIT Y OF FLORIDA

The first floor of the building accommodates a state of the art conference center, consisting of a large, media-rich auditorium, break out conference rooms, and a large media-equipped lobby capable of accommodating social, academic and student events. Amenities are centrally located to support and connect the laboratories and offices. The remainder of the first floor is clinical research space operated by the Institute on Aging, an interdisciplinary group involved in the areas of research, education and health care across all UF Colleges and Departments. Passive and active design strategies through the building led the facility to a LEED Platinum Certification.

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SIZE

? COMPLETION

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SIZE

538,000 sq. ft. COMPLETION

2014

FONDA ZIONE RI.MED BIOMEDICAL RESE ARCH AND BIOTECHNOLOGY CENTER

Carini, Sicily

This new Biomedical Research and Biotechnology Center is designed to be a new center for translational research pairing scientific researchers with practicing clinicians on a common campus. The master plan is comprised of a large research complex, a future 300-bed hospital and common shared elements such as an auditorium, employee cafĂŠ, administration complex and gardens. hok .com


SIZE

500,000 sq. ft. (Phase I) COMPLETION

2016


U N I V E R S I T Y AT B U F F A L O , S C H O O L O F MEDICINE AND BIOMEDICAL SCIENCES

Buffalo, New York

Located at the center of the region’s emerging bio-sciences corridor, this new medical school development will anchor a mixed-use district on campus and bring 1,200 students, faculty and staff downtown.

The new center will create connections that allow students, faculty, biomedical researchers and clinicians to move easily from classroom to bedside to lab. hok .com


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Biomedical and Translational Research Facilities  

An overview of HOK's experience with Biomedical and Translational Research Facilities with emphasis on Cancer Research.