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Technical application recommendations Geistlich Mucograft® Seal is an alternative to autogenous soft tissue grafts. Technical guidelines have been developed for the use of Geistlich Mucograft® Seal based on over five years clinical experience with Geistlich Mucograft® and the consensus reached at the meeting of the Geistlich Mucograft® Seal Advisory Committee (2013). When using Geistlich Mucograft® Seal, special attention should be paid:

Minimise invasion, maximise soft tissue outcome

Geistlich Mucograft® Seal Geistlich Mucograft® Seal has to be used with an alveolar filling material (e.g. Geistlich Bio-Oss® Collagen). Prior to applying Geistlich Mucograft® Seal, the adjoining soft tissue margins should be de-epithelialised. This allows soft-tissue cells to migrate from the softtissue border into the matrix. Geistlich Mucograft® Seal should be adapted to the defect size and applied in the dry state. Orientation of Geistlich Mucograft® Seal: The compact structure of the matrix should face towards the oral cavity and the spongy framework towards the extraction socket. The spongy structure of Geistlich Mucograft® Seal is marked with grooves.

Fixation of Geistlich Mucograft® Seal Geistlich Mucograft® Seal should be sutured with non-resorbable suture material and not glued. The good adaptation of the product to the tissue margins can be achieved with single-interrupted, double interrupted or cross suture, depending on the defect. The finest possible suture material should be selected that can be conveniently used by the surgeon. For single-interrupted sutures 5.0 or 6.0 sutures are recommended for cross sutures a 5.0 suture size is suitable. When suturing Geistlich Mucograft® Seal, assure a tension-free close adaptation of the device edges to the de-epithelialised marginal soft-tissue border of the extraction socket.

Collagen matrix for soft tissue regeneration in extraction sockets Available size: 8 mm diameter

Geistlich Bio-Oss® Collagen Spongiosa granules with 10% collagen, pre-formed block Available sizes: 100 mg 250 mg

1

Araujo M. et al., Int. J. Periodontics Restorative Dent. 2008; 28:123–135.

2

Araujo M. et al., Clinical oral implants research 2009; 20:433–440.

3

Jung RE et al. J Clin Periodontol. 2013 Jan, 40(1):90–8.

4

Geistlich Mucograft® Seal report on the meeting of the Advisory Committee, 2013, data on file.

5

Thoma D. et al., J. Clin. Periodontol 2012; 39:157–165.

6

Hämmerle C. et al., ITI Consensus statement FDDH; EM:supplementation.

For further application information, please also observe the technical guidelines.

Subsidiary Great Britain, Ireland Geistlich Sons Limited 1st Floor, Thorley House Bailey Lane Manchester Airport GB Manchester M90 4AB Phone +44 1 614 902 038 Fax +44 1 614 986 988 www.geistlich.co.uk

Manufacturer: Geistlich Pharma AG Business Unit Biomaterials Bahnhofstrasse 40 CH-6110 Wolhusen Tel. +41-41-4925 555 Fax +41-41-4925 639 www.geistlich-pharma.com

More details about our distribution partners: www.geistlich-pharma.com/mycontact

HSH 1718


Advantages of using Geistlich Bio-Oss® Collagen and Geistlich Mucograft® Seal > Horizontal and vertical bone loss can be largely compensated1-3 > Soft tissue management possible 8–10 weeks after dental extraction 4 > Minimally invasive3,4, lower morbidity4

Treatment options for the extraction socket

Immediate implantation

Fill the gap

Intact extraction socket* Geistlich Bio-Oss® or

Day 0

6

> Good wound healing3–5 and tissue integration4,5 > Natural colour and texture adaptation

+

Geistlich Mucograft® Seal

Geistlich Bio-Oss® Collagen

4,5

> Simple application and shorter operating times4 > Various therapy concepts possible: from early implantation 8–10 weeks after extraction through to late implantation or bridge restoration4

Early implantation Day 0

Intact extraction socket*

Spontaneous healing6 OR

As required: Guided bone regeneration at implant placement

+

8–10 weeks4

Geistlich Bio-Oss® Collagen

Geistlich Mucograft® Seal

+ Geistlich Bio-Gide®

Geistlich Bio-Oss®

Intact extraction socket*

+

Delayed or late implantation

Dr. Raffaele Cavalcanti, Bari, Italy

Advantage: Soft tissue management following tooth extraction «Ridge preservation with Geistlich Bio-Oss® Collagen and Geistlich Mucograft® Seal minimises ridge resorption in extraction sockets with preserved alveolar buccal walls. Soft-tissue quality and maturation after 8–10 weeks provides an ideal contour for early implant placement.»

Day 0

Geistlich Bio-Oss® Collagen

Geistlich Mucograft® Seal

+

after 3 months6 Defective extraction socket

+ Geistlich Bio-Oss® Collagen

Geistlich Bio-Gide®

Geistlich Bio-Oss®

Geistlich Bio-Gide®

Intact extraction socket*

+ Advantage: Preservation of the bone volume Geistlich Bio-Oss® Collagen and Geistlich Mucograft® Seal preserve significantly more bone volume than spontaneous healing.3

PD PhD Dr. Ronald E. Jung, Zurich, Switzerland

As required: Guided bone regeneration at implant placement

Geistlich Bio-Oss® Collagen

Bridge restoration Day 0

Geistlich Mucograft® Seal

6 months Defective extraction socket

+ Geistlich Bio-Oss® Collagen

Geistlich Bio-Gide®

*The definition of an intact extraction sockets varies among experts and includes buccal bone defects of 0 to 50%.

Bridge restoration


1718 mucograft flyer