The abuse of and addiction to opioids such as heroin, morphine, and prescription pain relievers is a serious global problem that affects the health, social, and economic welfare of all societies. Currently, the CDC has estimated 91 opioid overdoses per day in the U.S. and there is a greater need within our healthcare system to find solutions to end this epidemic. Medical Cannabis is a solution to our Opiate Dependency and we bring to you the evidence-based research to validate this claim in this important Issue of Cannabis Nurses Magazine: Opiate Dependency.