Von Willebrand Disease (vWD) is a common bleeding disorder caused due to missing or defect in von Willebrand factor (VWF), a clotting factor which helps blood to clot. Low amount of Willebrand factor (VWF) leads to severe and bleeding. There are four types of vWD namely Type 1 vWD, Type 2 vWD, Type 3 vWD, and Acquired vWD. Desmopressin is a common drug used for treatment of vWD, which is an antidiuretic hormone that triggers the release of VWF into the plasma and may increase levels of factor VIII.