@ResearchWales Issue 2

@ResearchWales Health and Care Research Wales Magazine - Issue 02 - June 2017

The magazine to showcase health and social care research Wales

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‘What is research?’

Find out how research is keeping you extrordinary

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New developments in social care research

Mental Capacity: Action in Research

“Research is critical to improving what

Developing a consensus to improve access to

happens now in social care services”

health and social care research for adults with

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impaired capacity to consent

Health and Care Research Wales Magazine - Issue 02 - June 2017

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Contents

The Wales School for Social Care Research

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Seal or Varnish?

Mental Capacity: Action in Research

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‘What What is is research?’ research? video PAG E 0 3

Foreword

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Professor Jon Bisson, Director of Health and Care Research Wales

Mental Capacity: Action in Research day

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News

Learning to lead our lives

Research news from across Wales

Monmouth Comprehensive School research

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Social care research

R&D Forum

New developments, including the launch of the Wales School for Social Care Research.

The annual NHS R&D Forum comes to Wales in 2018

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Seal or Varnish?

Combating teenage activity

Preventing tooth decay in children How can we help teenagers be more active?

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Ten things you didn’t know about ADHD PAG E 1 6

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International Clinical Trials Day Celebrating the contribution of 24,000 people who took part in research last year

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New mums study

What is research?

Pregnant women and new mothers feel like their health is ‘under surveillance

Watch our latest video

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Meet our fellows

Calendar

Health and Care Research Wales Magazine - Issue 02 - June 2017

to be put in place over the next year with

edition of @ResearchWales magazine. The

the implementation of consistent UK

articles highlight the excellent work being

study set-up processes in Wales, helping

undertaken and demonstrate a vibrant health

ensure excellent delivery and better use of

and social care research and development

resources.

community in Wales that is integrated with other sectors and benefits greatly from

A major development in the last few months

strong public involvement and engagement.

has been the finalisation of appointments to all 30 specialty lead posts in Wales. This

Health and Care Research Wales is now

group of highly experienced, predominantly

two years old and I am delighted that we

clinician/practitioner-researchers will

can already showcase many examples of

champion research in their fields and

excellent health and social care research that

represent Wales at UK-wide meetings to

are having a positive impact on the health,

facilitate involvement of Welsh sites in more

wellbeing and prosperity of the people in

high quality studies and their effective

Wales.

delivery.

Developing and disseminating evidence

I hope you enjoy this edition of @

leads to the delivery of high quality and

ResearchWales magazine and look forward

innovative services. Health and Care

to continuing to work together to ensure that

Research Wales has a major role to play in

Health and Care Research Wales builds on its

this and it is vital that research is used to

positive achievements to date.

deliver prudent health and social care.

A key priority for the next year is to build on

Professor Jon Bisson

the work already undertaken to develop a

Director, Health and Care Research Wales

Foreword

It is a pleasure to welcome you to the second

strategic approach to ensure the impactful delivery of research knowledge mobilisation in health and care services in Wales.

Over the last year, significant changes have been made to the way we support and deliver high quality research. We anticipate another key piece of the jigsaw

Health and Care Research Wales Magazine - Issue 02 - June 2017

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B ETS I CADWAL ADR U NIVER S IT Y H EA LTH BOAR D

News

Award win for Ysbyty Gwynedd team

Research news from across Wales

Ground-breaking research into the impact of long-term drug herapies to treat people with the chronic skin condition psoriasis has won a top award.

More than 140 psoriasis patients who are being treated at Betsi Cadwaladr University Health Board’s three acute hospitals are taking part in the national study.

The team at Ysbyty Gwynedd in Bangor have now won an award from the British Association of Dermatologists Biologic Interventions Register (BADBIR).

The award, which names Ysbyty Gwynedd as a ‘model centre’, is for recruiting the highest number of patients in North Wales to the UKwide study, which will continue to monitor patients until at least 2028.

The research aims to assess the long-term safety of biologic treatments for psoriasis, which target a specific area of a patient’s immune system.

D IA B ETES R ES EARCH U NIT CY M R U

Public Reference Panel

The Diabetes Research Unit Cymru’s Public Reference Panel has been established for over a year and is made up of eight members of the public.

As well as working with the Executive Group and research theme leads to shape research, group members have reviewed funding applications and helped develop and support public engagement activities.

Feedback from researchers who have received a review of their research summary: “I’m a new investigator and am working on a new programme of research. The insights will likely shape the way I think about and present this research beyond the current proposal.”

S AIL DATABANK

Celebrating ten years Professor David Ford, co-director at SAIL said: “The SAIL (Secure Anonymised Information Linkage) Databank has come a long way in ten years. We have already formed strong links with many research organisations, and we hope to forge relationships with new partners as we move forward.

“There will be challenges ahead, but we look to the future with excitement as we continue to work on improvements and novel developments to enable the best use of data

“The panel provided the opportunity for us to reassess how the application would be understood by potential reviewers. We would like to thank members for their invaluable contribution to the design of this study.”

to benefit population health and well-being.”

Download the 10 Year review to read the full story: saildatabank.com/wp-content/uploads/ SAIL_10_year_anniversary_brochure.pdf

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Health and Care Research Wales Magazine - Issue 02 - June 2017

WA LES CA NC E R RE SEA RC H C E NT RE

MONOCLE trial Patients with an uncommon form of cancer known as Chronic Myelomonocytic Leukaemia (CMML) are being recruited to a trial to test the safety and effectiveness of a new drug.

40 patients in the phase two MONOCLE trial will be treated with Tefinostat, allowing researchers to test the effectiveness of the drug in CMML, as well as monitoring side effects. Blood and bone marrow samples from patients will be tested in the laboratory to help us better understand how the drug works and to identify which patients are

The Wales Cancer Research Centre’s Dr Steven Knapper is the Chief Investigator leading the trial in Cardiff. He explains: “We are very excited to be in a position to commence the MONOCLE study which will, for the first time, allow us to assess the effects of Tefinostat, a monocyte-directed often-neglected haematological malignancy.

Hospital sites across the United Kingdom will be open for recruiting patients into the trial. I am extremely grateful to our funders Bloodwise and the CRT Pioneer Fund for making this study possible.”

The Early Phase Unit at Velindre is working in partnership with the Wales Cancer Research Centre to adopt its first combination trial, which is now open to a small number of eligible patients.

drug called Lynparza (olaparib) combined

CMML is an uncommon form of cancer that causes a build-up of cells called monocytes in the bone marrow and blood. It mainly affects older people and the average length of survival is only 11-17 months. Most patients with CMML are unsuitable for bone marrow transplant therapy and there are currently very few other treatment options.

side effects.

in the world to access the drug-radiation

The trial, which will look at the effects of a

Chronic Myelomonocytic Leukaemia:

monocytes without causing unacceptable

Welsh patients are to be some of the first combination trial, known as PARADIGM 2.

therapeutic agent, in patients with this

treatments which can target the abnormal

“This is the first ever early phase cancer trial combining drug and radiotherapy to be opened in Wales” Cutting-edge brain tumour treatment made available in Wales

most likely to benefit in future.

There is a pressing need for new drug

V ELIN D R E CANCER CEN TR E

with radiotherapy for patients with aggressive brain tumours, could lead to another treatment option being available to patients on the NHS.

Dr Robert Jones, who leads the Unit said, “The work we do here is vital in developing new and better treatments for cancer patients in Wales and beyond, and it is important that we can offer these trials in a more local setting for patients who otherwise may have to travel to Oxford or London. We are excited to be able to offer a new type of trial to patients, and hope that we continue to build on our expanding portfolio of early phase trials.”

Over the next five years, there will be a significant rise in the number of drug radiation studies available to cancer patients.

The increase in therapies will offer cancer patients across Wales a chance to access new treatments and improve patient outcomes.

About the trial Chief Investigator •

Glioblastoma is one of the most common types of brain tumours in adults and is usually treated with surgery and

Professor Anthony Chalmers

Supported by

radiotherapy. Radiotherapy damages DNA in cells, preventing their replication and growth.

Lynparza also prevents repair of damage to DNA so enhances the effect of radiotherapy.

The effectiveness of the combination will be

•

Cancer Research UK

•

AstraZeneca

•

NHS Greater Glasgow and Clyde

•

The Brain Tumour Charity

•

University of Glasgow

tested on a small number of cancer patients in this early phase trial.

Health and Care Research Wales Magazine - Issue 02 - June 2017

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H EA LTH AND CAR E R ES EARCH WAL ES

Continuing Professional Development accreditation All courses on our national research training programme are now accredited by the Continuing Professional Development (CPD)

accreditation of our training courses ensures we continue to maintain the high standard and quality of teaching we have become known for.”

Our training programme provides highquality training delivered across Wales by our team of expert facilitators. Find out more about our training courses: www.healthandcareresearch.gov.wales/ training-courses/what-courses-we-offer/

Certification Service. Courses include: Good Clinical Practice, Valid Informed Consent and

HE A LT H W I S E WA L E S

an Introduction to Research Methods.

Your information will protect the nation Since its launch in 2016, the HealthWise Wales

Certificates of attendance will now display the accreditation logo together with the allocated CPD (Continuing Professional Development) hours.

team has been working with the public to Lynette Lane, Senior Training and

achieve some ambitious goals.

Development Manager, said: “The CPD To encourage members of the public to share their health information, last month they launched a second advertising campaign.

The adverts highlight the importance of the public’s involvement in research and features participants who want to share their story.

You can hear their stories on the HealthWise Wales YouTube channel: www.youtube.com/channel/ UCdM2NSxdOtek404lV4inaKw The team is working hard to make the project a success to benefit the NHS and the public.

If you have any ideas or would like to help raise awareness; the project team is looking for people of different ages and backgrounds, from all over Wales to join in.

Your contribution, no matter how small, is invaluable to future generations.

WELS H AM BU L ANCE S ERVICE NH S TR U S T

39p patch is trialled in UK-wide study

Around 13 people per day experience a stroke in Wales according to latest statistics.

The researchers believe that the patch can improve outcomes for people who have had a stroke if the medicine is administered quickly.

So far, more than 10,000 participants have

A medicine skin patch, costing as little as

signed up. The results from some of the first

39p, could greatly improve the chances

The patch can be applied by paramedics in

studies will be shared later in the year.

of someone surviving a stroke, according

an ambulance before the patient arrives at

to research funded by the British Heart

A&E, saving vital time.

Find out how you can get involved here:

Foundation (BHF) Cymru.

“As a Trust we are proactive in taking part in

www.healthwisewales.gov.wales Researchers are testing a plaster-like patch

research into pre-hospital emergency care

Tel: 0800 9 172 172

which is applied to a patient’s shoulder or

in order to improve the clinical care of our

08:00 - 19:00 Monday to Friday

back and administers a drug whilst a patient

patients.

is travelling to hospital.

“We hope that by involving those who are

Email: healthwisewales@cardiff.ac.uk

The Welsh Ambulance Services NHS Trust

eligible in this UK-wide clinical trial we can

is one of the first ambulance services in the

develop a safe and effective pre-hospital

UK to take part in the RIGHT-2 trial in the

intervention for stroke patients.” Dr Brendan

Abertawe Bro Morgannwg and Hywel Dda

Lloyd, Welsh Ambulance Services NHS Trust.

University Health Board areas.

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Health and Care Research Wales Magazine - Issue 02 - June 2017

B R A IN UNI T

First robotic ‘neuromate’ in Wales aids epilepsy surgery The BRAIN Unit is celebrating the landmark

suffering up to six fits every day for the past 20

“It will enable us to investigate and treat even

stereoelectroencephalography (SEEG)

years.

the most complex cases to achieve seizure freedom for our patients. In collaboration

procedure, the first of its kind to be carried out With the robotic arm, it took Professor

with the BRAIN Unit, it will also enable us to

Gray 55 minutes to accurately identify

perform leading research for measuring brain

The ‘neuromate’ robot, named by creators

and operate on the epileptogenic zone in

signals and delivering therapies directly into

Renishaw, assisted Professor Gray, at the

a procedure that would normally take four

the brain, across many neurological diseases,”

University Hospital of Wales, during surgery

hours. Follow-up surgery a week later was

said Professor Gray.

while he used intracerebral electrodes to

performed in the hope of relieving Denise

measure electrical signals in the brain.

of her epileptic symptoms.

with robotic assistance in Wales.

Denise appeared alongside Professor Gray on BBC Wales television to discuss her

Patient Denise Casey, from Neath Port Talbot,

“The Renishaw robot is a significant step

experience. Watch the interview here:

was diagnosed with epilepsy when she was 31,

forward for epilepsy surgery in Wales.

www.bbc.co.uk/news/uk-wales-39513139

WELSH HE A LT H E CO N O M ICS SUPPORT SE RVI C E

Filling the gap where patients used to fall

services makes when they are available in

described seven broad types of valued

clinics. These services are typically delivered

service and support provided by ECLOs,

by eye clinic liaison officers (ECLOs).

working in ways which reflect the individual circumstances of different clinics and

The report identifies three areas of impact:

hospitals.

The Swansea Centre for Health Economics

On patients: ECLOs help those with the

On services: ECLOs enhance and broaden

(SCHE) has completed a major study in

greatest needs and appear to maintain their

the care clinical services provide. They have

partnership with the Welsh Institute for

health-related quality of life by providing a

the potential to not only reduce patients’

Health and Social Care. The study, which was

wide range of well-targeted, well-appreciated

longer-term care needs but to release NHS

commissioned by the Royal National Institute

services.

staff to perform their clinical roles. Evidence

of Blind People (RNIB), evaluated the impact of patient information and support services in UK

of their impact on productivity and efficiency On clinics: Across the UK, the study

is less clear, but they do make a contribution

NHS ophthalmology.

to various other NHS objectives

The study aimed to understand the

relevant to all four

difference providing information and support

nations.

Health and Care Research Wales Magazine - Issue 02 - June 2017

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N O RTH WAL ES O RGANIS AT IO N F O R R A N DO M IS ED T R IAL S IN H EA LTH

Supporting the world’s largest study of preterm children One of the studies NWORTH is currently supporting is Respiratory Health Outcomes in Neonates (RHiNO).

The research study - which is taking place at

CA RD IFF AN D VA L E UN IVE RS I T Y

the new Paediatric Clinical Research Facility - aims to understand why prematurely born children develop lung disease and to identify

Paediatric Clinical Research Facility

the optimal treatment for their lung disease.

The first Paediatric Clinical Research Facility

management and statistical support.

NWORTH is conducting the study, along with the RHINO research team, offering trial

(PCRF) in Wales has opened.

Based in the Noah’s Ark Children’s Hospital

It focuses on patients with chest injuries

for Wales and supported by the Children and

which, while being relatively minor, can lead

Women’s Clinical Board, the vision is that

to serious, potentially fatal complications.

the facility will act as a hub for paediatric

Often, these complications don’t emerge for

research, attracting new high quality research

several days, leading to people returning to

programmes and expertise to Cardiff.

hospital as emergency cases.

Rhian Thomas-Turner, Operations Manager,

Dr Battle, who has been working on the

explains: “The PCRF, which offers the first

project for a decade, carried out initial

protected space for under 18s, offers

work at Morriston Hospital. The research

significant potential to expand and

resulted in the creation of a risk factor

enhance the current levels of research and

based diagnostic tool that can identify from

development within paediatric services

the start which patients are most at risk of

across Wales.

developing complications.

“As well as collaborating with universities and health boards, we’re also looking to build a broad commercial research portfolio.

This will not only give paediatric patients an extra treatment option, but will increase research capacity within the facility.”

A team of paediatric research nurses including Gail Marshall, Jennifer Muller from the Children’s Hospital and Deb McNee who

A B ERTAWE BRO M O RGANNWG U N IV ER S IT Y H EALT H BOAR D & S A IL DATABANK

Morriston researchers secure £230,000 for next stage of lifesaving study

But now a UK trial is needed to test whether the screening tool works in clinical practice.

The grant has funded a feasibility study, involving four hospitals in Salford, Manchester, Taunton and Newport, with around 300 patients taking part.

Dr Battle explains: “The feasibility study allows us to test all the different aspects

is part of the research delivery staff will be

Researchers at Morriston Hospital, working

of the methods for the big trial. After that

helping to deliver studies.

on a study that could save lives around the

we will recruit more hospitals and probably

UK, have been awarded a £230,000 Research

involve a couple of thousand patients, to test

If you would like more information on the

for Patient and Public Benefit grant to take it

whether the score actually saves lives.

PCRF or have an opportunity you’d like to

to the next stage.

“The ultimate goal will be getting it into NICE

discuss, contact Rhian Thomas-Turner, PCRF Operations Manager:

The study, led by Dr Ceri Battle (pictured

guidelines, which we hope will happen in

Rhian.Thomas-turner@wales.nhs.uk

above with her supervisor, Professor Adrian

perhaps three or four years.”

Evans), is being carried out as part of Morriston’s academic emergency medicine

Research for Patient and Public Benefit grant:

research programme.

www.healthandcareresearch.gov.wales/ health-research-grant-and-rfppb/

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Health and Care Research Wales Magazine - Issue 02 - June 2017

PRIME C E NT RE WA L E S

Antibiotics not effective for clinically infected eczema in children Findings from a study led by PRIME Centre Wales and Cardiff University suggest there is no meaningful benefit from the use of either oral or topical antibiotics for milder clinically infected eczema in children.

Eczema is common, affecting around one in five children in the UK. Eczema sometimes gets worse, or ‘flares’. Doctors currently prescribe antibiotics as a treatment for around 40 per cent of these flares, despite there being little research to show whether the drugs work.

infection, children with milder eczema are

The CREAM study was designed to find out if oral (taken by mouth) or topical (creams and ointments applied to the skin) antibiotics help improve eczema severity in children with infected eczema.

Results from the analysis of data showed no significant difference between the groups in the resolution of eczema symptoms at two

Swansea University and Public Health Wales.

unlikely to benefit from antibiotics, and their use can promote resistance and allergy

Health and Care Research Wales delivery staff

or skin sensitization.

recruited and supported the study.

“Providing or stepping up the potency

The study was funded by the National

of topical corticosteroids and emollients

Institute for Health Rsearch Health Technology

should be the main focus in the care of

Assessment Programme

milder clinically infected eczema flares.”

www.healthandcareresearch.gov.wales/ funding

The CREAM (ChildRen with Eczema,

weeks, four weeks or three months.

Dr Nick Francis, Clinical Reader at Cardiff University and practicing GP, who led the study said: “Topical antibiotics, often in combination with products with topical corticosteroids, are frequently used to treat eczema flares. Our research shows that even if there are signs of

WA LES G E NE PA RK

Antibiotic Management) study was led

The CREAM study

by Dr Nick Francis and Professor Frank

www.cream-study.co.uk/

Sullivan, University of Toronto, coordinated by the Centre for Trials Research at Cardiff University, and in collaboration with colleagues at University of Bristol, University of Oxford, University of Dundee,

acknowledge individuals or teams who have made a real difference in meeting the

Outstanding contribution to engagement

objectives, values and beliefs of the School of Medicine. The inaugural awards ceremony was held at Cardiff City Hall on 18 October 2016.

The Wales Gene Park Genetics Engagement Programme has been delivering events to

The Wales Gene Park has been recognised in an ‘Outstanding Contribution to Engagement’ award. The accolade is part of the STAR (STaff Appreciation & Recognition) awards, launched by Cardiff University in 2016 to

over 58,500 health professionals, school

Left to right: Jayne Dowden (Chief Operating

and college students, patients and the

Officer, Cardiff University), Emma Hughes (Wales

public across Wales for over 13 years. The

Development Officer, Genetic Alliance UK),

programme has expanded over the years and

Angela Burgess (Education and Engagement

is going from strength to strength, adapting

Project Manager, Wales Gene Park), Rhian Morgan

to meet the needs of its audiences and

(Education and Engagement Officer, Wales Gene

keeping abreast of the changes in this fast-

Park) and Professor Ian Weeks (Acting Head, School

moving scientific field.

of Medicine, Cardiff University).

Health and Care Research Wales Magazine - Issue 02 - June 2017

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FE AT U RED

The Wales School for Social Care Research launches

Improving care through research and evidence The Wales School for Social Care Research officially launched at the Temple of Peace in Cardiff, on 14 February 2017.

The School has been created to improve and increase social care research in Wales. Its close links with social service providers will ensure that care and support for children, young people and adults in Wales is based on solid evidence of what works.

Rebecca Evans, Minister for Social Services and Public Health, who spoke at the launch, said: “The Welsh Government has prioritised social care as a sector of national strategic importance.

“Social care must be high quality and effective, and the work undertaken at the Wales School for Social Care Research will help ensure that we develop evidenceinformed policies and services that meet the needs of people in Wales. Today’s research is tomorrow’s care.”

Professor Fiona Verity, Director of the Wales School for Social Care Research, explains: “At the heart of the School will be a genuine approach to working together; sharing and generating new knowledge that can make a difference. We believe the School is a vital step in improving social care research across Wales in ways that strengthen and build on what is already happening across the country.

“Research is critical to improving what happens now in social care services, and can also tell us how to improve the wellbeing of individuals, families and communities.”

The School will work with social care providers to help improve care for children, young people and adults as outlined in The Social Services and Well-being (Wales) Act 2014.

There will also be an emphasis on involving

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Health and Care Research Wales Magazine - Issue 02 - June 2017

and engaging the public in social care research, helping to better meet the needs of individuals, their families and carers.

Facebook: www.facebook.com/WSSCR Twitter: @WSSCR

New Developments in Social Care Research

“The work undertaken at the Wales School for Social Care Research will help ensure that we develop evidenceinformed policies and services that meet the needs of people in Wales” Rebecca Evans The scale of need indicates the importance of robust research to both increase knowledge and to inform practice. In response to this, the Welsh Government has made a commitment to support social care research, which has seen the launch of the

Social care services have traditionally had a lower profile than health services. It may be because social care activities are less visible, often taking place in people’s homes rather than in public buildings such as hospitals and clinics. But low visibility doesn’t equate

Wales School for Social Care Research. The

improving social care policy and practice.

School will lead in developing capacity in

These initiatives align with an existing

social care research, promoting research-

programme of work funded by Health and

mindedness in practice, and fully-embedding

Care Research Wales to support health and

public involvement in social care research in

social care research teams who have a track

Wales.

record of research excellence, to address areas of public need. These developments

to low numbers. Data from StatsWales

In addition to this, Social Care Wales will

(2015-16) show there were more than twice

launch a consultation on the new Social

as many places in care homes (26,259) as

Care Research Strategy, which has been

hospital beds (10,935) in Wales. Most people

developed jointly with Health and Care

who have social care needs remain in their

Research Wales and the Wales School for

own home, supported by formal services or

Social Care Research, in summer 2017.

friends and family. Carers Wales reported

This is underpinned by the aim for Wales

If you would like to know more about these

that over 320,000 people were caring for

to be renowned for the development,

developments, please contact Dr Catherine

others and that 123,000 people take on a

conduct and use of excellent social care

Poulter, Social Care Research Manager, Health

new caring role each year.

research that supports individuals, families

and Care Research Wales Support Centre

and communities through informing and

Catherine.Poulter@wales.nhs.uk

will not only complement the world class social care research that is already taking place in Wales but will also ensure that the research findings make a difference to people in Wales.

Health and Care Research Wales Magazine - Issue 02 - June 2017

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FE AT U RED

Seal or Varnish?

Preventing tooth decay in children Research published in May 2017 found that applying fluoride varnish to children’s teeth is just as effective as alternative expensive treatments.

Since fluoride toothpaste was introduced in the early 1970s, we’ve seen

Novel aspects of this trial and the contribution to revised trial regulations

huge improvements in oral health. But tooth

Fluoride Varnish is a prescription only

decay remains an issue.

medicine, which meant that full regulations

Diet is a major factor in

that apply to a Controlled Trial of an

the growth of plaque,

Investigational Medicinal Product (CTIMP) applied. This led to interesting discussions

with sugary foods and

The Seal or Varnish study was led by

with the Medicines and Healthcare products

Professor Ivor Chestnutt from Cardiff

Regulatory Agency (MHRA) over the

drinks being the main

University School of Dentistry, in

application of CTIMP protocols in a mobile

contributors. Rates

collaboration with Cardiff and Vale University

dental clinic at a time when the MHRA were

Health Board Community Dental Service.

producing their Risk-adapted Approaches

of decay are often

Professor Chestnutt and his team set out

to the Management of Clinical Trials of

higher in children who

to discover whether decay on first adult

Investigational Medicinal Products. Professor

live in disadvantaged

molars can be prevented by two different

Chestnutt believes that discussions over the

treatments: fissure sealants (seal) or fluoride

resulting risk-adapted approach would make

communities.

varnish (varnish).

running a similar trial again less taxing.

The first adult molars that come through when

The role of Health and Care Research Wales

More than 800 children were treated as part of the trial and given either ‘seal’ or

children are around six years old are particularly

‘varnish’. The children, from disadvantaged communities across Cardiff and Vale and

Professor Ivor Chestnutt commented: “This

Cwm Taf university health board areas,

study shows that we have the infrastructure

vulnerable to decay –

attended a mobile dental clinic which visited

and support in Wales to run what has been one of the largest dental clinical trials

which is caused by a

schools every six months for three years.

build-up of plaque that

conducted in recent years.

attacks the teeth.

Professor Ivor Chestnutt said: “Our research has shown that the fluoride varnish – which

“The support of Health and Care Research

is simple to apply – does prevent tooth

Wales and its predecessor bodies have been

decay just as well as a more difficult and

crucial in us being able to compete for this

expensive treatment. Over the three years

type of work and to deliver a world leading

there was a cost saving of £68.13 per child in

study in the area of pragmatic clinical trials

the varnish group.

in Wales. The research infrastructure in the form of the Trials Unit and the financial

“The study provides invaluable evidence

support for the excess treatment and service

for National Health Service dental services

support costs, which are considerable in a

in the UK and has implications for dental

study such as this, are crucial.

prevention around the world.”

“We also benefitted from input from Health and Care Research Wales research nurses

who helped us chase up responses to parental questionnaires that were important in informing the health economic analysis that was an integral part of the study.”

The setting for the trial was the Welsh Oral Health Improvement Programme – Designed to Smile (www.designedtosmile.co.uk). The study was funded by the National Institute for Health Research (NIHR) and coordinated by the Centre for Trials Research at Cardiff University.

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Health and Care Research Wales Magazine - Issue 02 - June 2017

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“Teeth designed to last a lifetime, frequently have to be extracted within a few years of eruption.�

Professor Chestnutt

Name Surname Name Surname

Health and Care Research Wales Magazine - Issue 02 - June 2017

13

F EATURED

Ten things you didn’t know about ADHD Professor Anita Thapar is Clinical Professor in the Division of Psychological Medicine and Clinical Neurosciences at Cardiff University. She is also senior investigator in the National Centre for Mental Health (NCMH).

You’ve probably heard of Attention Deficit Hyperactivity Disorder – better known as ADHD, and is one of the many conditions studied by NCMH researchers. It’s a relatively common condition that is thought to affect somewhere between 1 in 100 to 3 in 100 children in the UK. But there are a lot of

1

misconceptions. Here, Professor Thapar tells us ten things you might not know about ADHD.

ADHD is not just ‘naughty ’ behaviour ADHD is a combination of attention difficulties, hyperactivity and impulsive behaviour which causes real problems for how children get on both at home and at school, and affects learning and relationships. This pattern of symptoms has a strong biological basis.

2

ADHD is not ‘new’

ADHD hasn’t become more common recently

3

The prevalence of ADHD isn’t increasing – research shows the number of people with ADHD hasn’t changed over recent years. However, there is now more awareness of and recognition of ADHD, so more people are being diagnosed.

Children with the clinical features that characterise ADHD were described by a paediatrician in The Lancet medical journal as early as 1902, and there are also much earlier descriptions – so it certainly isn’t a ‘new’ condition.

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Health and Care Research Wales Magazine - Issue 02 - June 2017

4

Some children grow out of ADHD, but some don’t The course of ADHD is very variable. While some individuals no longer experience ADHD symptoms when they reach adulthood, many will continue to meet all the criteria for a diagnosis, or will at least retain some of the symptoms.

5

A diagnosis of ADHD doesn’t necessarily mean a child will be prescribed medication In the UK, behavioural interventions are the first line of treatment for children with milder ADHD. Medication is only used when ADHD symptoms are severe and are causing major difficulties. Even then,

67

medication shouldn’t be given without behavioural interventions.

There’s no test for ADHD Neither blood tests nor brain scans can tell whether or not someone has ADHD. The diagnosis is made by taking a careful clinical history, including information from home and school, and by observing the child in a clinic setting.

ADHD has nothing to do with junk food, or bad parenting

So far there has been no substantial evidence to suggest sugar and artificial food additives play any part in ADHD. There is also little evidence to show dietary changes can help with ADHD symptoms.

8

ADHD is certainly not caused by bad parenting or lack of discipline.

Parenting a child with ADHD can be challenging, but specific parenting strategies with more structure, routines and positive reinforcement can help.

There is no single cause for ADHD We know so far that ADHD is a largely genetic disorder, but some environmental factors also play a role. We still have yet to understand how these different factors contribute to developing

9

the condition.

Genetics are important, but there’s no ‘ADHD gene’ While ADHD is strongly linked to our genetics, there isn’t a specific gene that causes it – instead there are many different genes that seem to contribute to our risk of developing ADHD. We also know these genes don’t entirely account for the development of ADHD, so things in a young person’s environment must also be involved. We don’t know exactly what yet, which is why research like ours is taking place. This

10

is also why there isn’t a genetic test that can tell us whether or not someone has ADHD.

ADHD can run in families, but doesn’t always People who have a close relative with ADHD are more likely to have ADHD, or features of ADHD themselves, than people who don’t.

However, as described above, the way genes contribute to ADHD isn’t straightforward. This means someone with a close relative with ADHD won’t necessarily have the condition themselves, and someone with ADHD might have no other relatives with it.

The way genes interact with other factors is extremely complicated, which is why research in this area is so important.

For more information from the NCMH about ADHD visit: www.ncmh.info/conditions-we-study/attention-deficit-hyperactivityHealth and Care Research Wales Magazine - Issue 02 - June 2017

15

FE AT U RED

Pregnant women and new mothers feel like their health is ‘under surveillance’

New mums and pregnant women today feel more judged than ever before, according to a recently published study from the South East Wales Trials Unit.

The study achieved significant media coverage, striking a chord with expectant and new mums across the UK. Lead author of the research, Aimee Grant, tells us about what they discovered after talking to mothers and grandmothers from across South Wales.

“

Pregnancy is a time when women are

expected to make changes to their health in order to benefit their unborn child. The list of ‘risky behaviours’ has increased significantly over the past 50 years, and today expectant mothers are advised to cut out alcohol, cigarettes and a range of foods, among other things. After their baby is born, women are reminded of the superiority of breast milk over formula – and can feel guilty whichever they choose.

But we’ve found that women aren’t left alone in their pre and postnatal health endeavours: friends, family and even strangers are all also policing their behaviour, focusing on anything thought to be risky to the baby’s health.

We spoke to six mothers, with babies aged two years and under, and their own mothers (the grandmothers) to tell us their experiences of infant feeding. Most reported that as soon as they were pregnant, they were asked about how they were going to be feeding their baby by acquaintances, friends and family. Everybody who asked appeared to have an opinion on what the ‘right’ choice should be.

Though most questioners acted with good intentions, some of the mums reported more intrusive and judgmental experiences.

This ever present low level surveillance and policing continued when the babies were born too, this time focusing on feeding. In

16

Health and Care Research Wales Magazine - Issue 02 - June 2017

general, the mothers said that pressure from health professionals was less than from other sources.

Unhelpful and often incorrect feeding advice came from a broad range of sources.

We heard that friends would push some women to feed their babies differently, and eventually the mums withdrew from these friendships to stop the flow of advice. Family and friends also judged women for how they fed their baby, for example criticising for breastfeeding frequently (a normal behaviour in young babies).

Most surprisingly, pressure continued to come from strangers. Mothers were questioned by strangers about what milk was being fed to babies from bottles in public.

One of the mums told researchers about her experience in a café.

Tanya, who was pregnant at the time, was having lunch with her mother. They didn’t expect the waiter to tell them what to eat.

A fear of negative judgement also existed around the preparation of formula: one mum

But according to Tanya he acted “like the kind of food police”.

reported hiding the powder under the table so as not to be seen.

“He said ‘The only things you can have are, um, cheese and pickle’.”

For new breastfeeding mothers, it is important they feel able to do so in public.

New motherhood is exhausting and finding the time to express breastmilk to use in public adds a further time-consuming task to

“It was just like, ‘We can’t serve you this.’ It was like he was the pregnancy expert.”

Tanya also told us that in another cafe, a man cleaning the floor had reacted to her getting out a bottle of expressed milk by asking her if she was breastfeeding.

their days. So the policing of new mother’s behaviour in public is likely to contribute to

She simply replied: “Yes”, but later admitted: “It’s quite intrusive ... I wouldn’t walk

the UK’s low rates of breastfeeding.

up to him and say ‘What did you have for your lunch today?’”

Alongside this, the UK does not currently

By contrast, Tanya’s mother Diane told the researchers that she had not

have a strong breastfeeding culture or

experienced anything like the same pressure to breastfeed or eat certain foods

adequate interventions to help mums to meet their breastfeeding goals, so this means

when she was a young mother.

that knowledge and support about how to breastfeed is not passed on to new mothers.

This explains why 81% of new mums start breastfeeding, but only 55% are still

Associate at the South East Wales Trials Unit.

breastfeeding at six weeks. For this reason,

Researchers: Miss Ruby Marzella, summer

it is really important that mums who are

placement student, School of Medicine,

formula feeding are not stigmatised when

Cardiff University; Dr Dawn Mannay, Senior

they feed their babies.

Lecturer, School of Social Sciences, Cardiff University.

The best advice to take is that if you see a woman you don’t know, who is pregnant or

The study was funded by the Children and

has a baby with her, think carefully before

Young People’s Research Network, who were

asking questions about infant feeding. Your

part of Health and Care Research Wales.

”

questions and comments could be making a difficult situation worse.

Aimee is currently working on an animated video to help disseminate the findings on

January this year. This second project examined health and wellbeing in pregnancy (and health behaviours such as smoking in pregnancy and infant feeding) from a holistic perspective, considering the women’s life history and current circumstances.

Women were interviewed three times, using participatory tasks to help them lead the interview. She is currently finalising papers for publication from this project and plans to further pursue this research later in the year.

If you have any questions or would like any

social media.

further information, please contact Aimee

from a piece originally written for The

Aimee has also led on a larger study funded

622).

Conversation.

by the Wellcome Trust’s Institution Strategic

Research Lead: Dr Aimee Grant, Research

Support Fund, which was completed in

The above is an amended extract taken

Grant (GrantA2@cardiff.ac.uk ; 02920 687

Health and Care Research Wales Magazine - Issue 02 - June 2017

17

F E AT URED

Meet our fellows Health and Care Research Wales runs a number of funding schemes designed to stimulate excellence in health and social care research.

Our Health Research Fellowship Award

“As graduation approached I started looking

aims to support individuals to become

at my options. I was especially interested in

independent researchers and to undertake

diseases. Why do they happen? What can be

high-quality research. Find out more

done to help people and families affected

information about our funding schemes: www.healthandcareresearch.gov.wales/

by them?

funding/our-funding-schemes/

“So the logical next step was to do a PhD. I started applying for projects that sounded

Here, we find out a bit more about three

interesting, and I was successful in applying

of our health fellows and the projects they

for a Huntington’s disease research project

secured funding for.

within the Brain Repair Group.

Dr Emma Yhnell, Cardiff University

“During my PhD I conducted some research into cognitive training in Huntington’s disease, which allowed me to apply for further research funding to translate ideas into the patient clinic. Initially, I was able to secure research funding from the Jacque and Gloria Gossweiler Foundation to use brain imaging to try to see if computer game brain training changes the structure of the brain.”

Emma’s Health Research Fellowship Award “In 2016, after completing my PhD, I was awarded the Health Research Fellowship Award to further explore computer game brain training, looking at personalising cognitive training and how feasible it is for people with Huntington’s disease – something that’s never been done before.

Title: Using computer based cognitive training to provide a personalised

“Based on pre-clinical work and research

therapeutic intervention for people with

into other brain diseases we think computer

Huntington’s disease

game brain training has the potential to be

How I got here

beneficial in Huntington’s disease, but we

“I’ve always loved science. In 2009 I started

have to test this to be sure.

my first degree in biochemistry at Cardiff University, which confirmed that science was

“I love talking to patients and feeling that I

where I wanted to work.

can make a real difference to people’s lives.

18

I get paid to do something I love and I really appreciate that.”

Dr Nathan Bray, Bangor University Title: Mobility and Quality of Life: Improving methods of economic evaluation of assistive technologies for people with impaired mobility In the UK more than 11 million people live with an impairment, disability or limiting chronic illness. Many people rely on mobility aids, such as wheelchairs, to help them move around and maintain independence.

The NHS supports more than 1.2 million people with long-term mobility needs, half a million of which are working age adults. More evidence is needed to understand which devices and interventions are the most costeffective means of improving mobility and quality of life.

The aim of this project is to develop a mobility-related quality of life outcome measure, which will help researchers and medical professionals to understand how different mobility aids effect the quality of

Health and Care Research Wales Magazine - Issue 02 - June 2017

“I love the challenge of answering questions nobody knows the answers to. There is no better feeling than finally getting the results of an experiment that you have been working on for two years.” Dr Emma Yhnell Dr Kelly Morgan, Cardiff University

But later research suggested that schemes are often not delivered consistently after a trial has finished. Plus, there is little evidence relating to the effects of schemes like exercise referral on long term health outcomes.

Kelly is investigating post-trial NERS implementation across all 22 local

life of people with mobility impairments.

authorities in Wales, and aims to evaluate

This novel outcome measure will also enable

the longer-term physical and mental health

health economists to assess the relative cost-

benefits of NERS for patients.

effectiveness of different mobility aids.

Nathan will be interviewing people who

She hopes that the evidence will help

use mobility aids, then developing an

understand what kinds of changes can be

outcome measure questionnaire based on

made to NERS to meet the needs of local

their responses. He will then validate the

stakeholders without compromising the

questionnaire and develop a preference-

effects of the scheme. The research will also

based scoring system.

“I have found my career

reveal more about the longer-term health Physical activity is related to lowered

outcomes for NERS patients compared

risk of heart disease and diabetes, and

to other patients who are eligible for the

improved well-being. But most adults

scheme but have not taken part.

in Wales do not meet public health

in research to be fulfilling,

recommendations for physical activity.

“The best part about

challenging and exciting; to

In 2007, a National Exercise Referral

being a researcher

date I have dedicated my

Scheme (NERS) was introduced in Wales to increase activity levels among patients

is the opportunity to

career to disability research

who are most at risk of health problems

continually learn, work

and I hope my work will

that could be prevented by physical activity.

with individuals from all

have a positive impact on the lives of people with disabilities.”

Dr Nathan Bray

different sectors, all the An evaluation of the scheme showed the scheme benefitted patients referred for both coronary heart disease and mental health problems. It all looked promising, so NERS was rolled-out across all local authorities in Wales in 2012.

while striving to make a difference to the health of the public.”

Dr Kelly Morgan

Health and Care Research Wales Magazine - Issue 02 - June 2017

19

F E AT UR ED

Mental Capacity: Action in Research On 16 March 2017, researchers and members of the public from across the UK converged on City Hall in Cardiff.

Together, they aimed to develop a consensus

delegates on their understanding of the

to improve access to health and social care

principles of the Mental Capacity Act and the

research for adults with impaired capacity to

need for change.

consent.

The second keynote was from William The day was sponsored by the National

Mieville-Hawkins, who was joined by

Mental Capacity Forum, Welsh Government

members of his family to give a very

and Health and Care Research Wales, and

moving account of his ongoing recovery

was unique in bringing together research

from a catastrophic brain injury. In an

leaders and the public from different

inspirational address, William and his

disciplines and care settings.

family sharply highlighted the need for evidence-based improvements in services

It was the first step in the development of an

and care, and the imperative to work closely

easy-to-read guide for researchers, people

with those directly affected. William’s blog

with impaired capacity and the public around application of the Mental Capacity Act to

on his day in Cardiff can be viewed here mybraininjuryrecoveryblog.wordpress.

health and social care research.

com/2017/03/16/amazingly-proud/

Two keynote speakers galvanised the

A series of short presentations gave further

delegates into action. Firstly, Baroness Finlay

insights into research with adults with

of Llandaff, Chair of the National Mental

impaired capacity from legal (Helydd Wyn),

Capacity Forum, passionately challenged

researcher (Vicky Shepherd), participant

20

Health and Care Research Wales Magazine - Issue 02 - June 2017

(Charlotte Harding) and carer (Caryl Kelly) perspectives. These set the scene for workshops in emergency care, intensive care,

5 Principles of the Mental Capacity Act

learning disability, dementia care, mental health and end of life/palliative care, where delegates highlighted the key issues and challenges within each specialty area. The themes from each workshop were brought back to the whole group to begin to develop consensus statements.

The commitment of Welsh Government to improving the access of people with impaired capacity to research and to ongoing service development was underlined by Vaughan Gething, Cabinet Secretary for Health, Well-being and Sport, who spoke of the opportunities in Wales through established research and lay communities to work closely with policy-makers.

The proceedings of the whole day were captured as a visual ‘map’.

1.

Least restrictive option

2.

Best interests

3.

Unwise decisions

4.

Support individual

5.

Presume capacity

All delegates will now be involved in the ongoing development of easy-read resources in this field.

If you would like further information or would like to be added to the circulation list to be kept up-to-date with further work, please contact healthandcareresearch@wales.nhs.uk

Health and Care Research Wales Magazine - Issue 02 - June 2017

21

FE ATUR ED

“Learning to lead our lives”

Researchers at PRIME Centre Wales have tracked an innovative approach to student health and well-being that t

Deputy headteacher of Monmouth Comprehensive School, Andy Williams, introduces restorative practice and tells us about the benefits it has brought to his school

At Monmouth Comprehensive we see academic errors as accidental and students are supported. But we also see errors in behaviour as accidental, and when

“In the face of pressure

relationships are harmed, our restorative

from various sources for

practice mirrors the academic approach, and

schools to become exam

provides support.

factories, the restorative Our outcomes over the past five years demonstrate the significant contribution that

model supports our

restorative practice has made to the wellbeing

young people in leading

of our students, staff and also the wider

their lives as healthy,

community: • The number of students receiving a fixed-term exclusion dropped by 95%

resilient, centred and valued individuals.”

• The number of days lost through exclusion dropped from 160.5 to 2 • Attendance figures at the school are at their highest level in its history

R

• All students at the school have left with a estorative practice has transformed

qualification

our climate, our language and our

• Staff illness with a stress-related tag has

culture, and we feel that every school could benefit from this model.

dropped by 82% over the same period.

• Anti-social behaviour involving youths in Monmouth has dropped by 48% in

A restorative school emphasises the

three years.

importance of relationships for supporting emotional wellbeing, resolving conflict and

Our approach to teaching and learning

preventing harm.

builds relationships and self-esteem from the classroom out, starting with the young

The practice is based on the values of

person’s experience and giving them skills.

restorative justice, used in a criminal justice

In line with our core restorative beliefs, we

setting. It’s about empowering individuals by

support young people in expressing their

giving them a voice.

22

perspectives, their thoughts and feelings, strengthening their sense of self.

In addition, the school is now exploring the links between developing restorative practice and mental health and wellbeing.

Building self-confidence and self-worth through expressing and exploring our personal narratives, linked to the cognitive and affective aspects of our nature and through being able to express our need along with supporting the needs of others.

The above is an extract from a piece originally published in SecEd magazine.

Health and Care Research Wales Magazine - Issue 02 - June 2017

they hope can be rolled out across schools in Wales

The role of research

What did we find?

Students and staff experience reflected and confirmed the principles of restorative

Dr Nina Gobat, Research Fellow from PRIME

practice and helped us better understand

Centre Wales, tells us about how she got

how we think the approach works to achieve

involved in the project.

its outcomes. Students described feeling valued and confident. They were able to

What did we do?

articulate how they felt – which really stood

We used a new method of developing

a commitment to understanding student

out for me. And for staff? They developed

interventions called a pragmatic formative evaluation. To do this we looked at the

behaviour and a shift in focus away from using punishment and reward to focusing on relationships. Longer term outcomes

evidence on restorative approaches and

included increased school connectedness,

worked with Andy to map out what we

positive student engagement in learning

thought was happening in the school in a

and enhanced school reputation. Students

model. We then ran several focus groups

described the school culture as inclusive,

with staff and students and interviewed further refine it to explore underdeveloped areas.

Staff and senior leadership commitment,

The novelty of the work is that we

is fundamental to the progression and

investment and ownership of the approach,

collaborated with innovation that seemed to be working already at the “front line”, i.e.

maintenance of the approach. But there are challenges too of course, such as staff

in the school, rather than try and impose our research ideas onto existing systems. intervention to continue and grow in the school over time, as well as things that challenge its continuation.

approach and tensions between wellbeing and academic attainment outcomes. It’s an on-going process of reflection and improvement to keep restorative practice alive and well.

trustworthy and supportive.

senior leadership to test this model, and

We could identify what has allowed this

changes, lack of consistency in delivering the

“We’re trying to think about health at a much earlier stage. It’s also about finding new ways of carrying out research.”

“(Wellbeing) is what the school runs on. If students feel safe and secure, almost like loved, it’s like a big family and then they’re more likely to concentrate and get on with work.” – student

Health and Care Research Wales Magazine - Issue 02 - June 2017

23

NEWS

R&D Forum comes to Wales The NHS R&D Forum, Health and Care Research Wales and the Health Research Authority are delighted to announce that the 2018 Annual NHS R&D Forum will be held on the 14 and 15 May 2018 at the Celtic Manor, Newport.

The 2018 event will coincide with the 70th anniversary of the NHS. The Celtic Manor will host the the Forum, allowing more space for sessions, exhibition and workshops.

What were the outcomes?

(the Centre for Development and Evaluation of Complex Interventions for Public Health

Professor Jon Bisson, Director Health and

The main outcome of this research has been

Improvement) was key to the success of the

Care Research Wales said: “We look forward

the co-production of a model for a whole

project.

to welcoming the R&D community across

school restorative approach that impacts on

the UK to this great event and to celebrate

student wellbeing. The approach adopted

School Health Research Network is funded

the importance of research at the exciting

in Monmouth is an example of front-line

through Health and Care Research Wales’

milestone of the 70th anniversary of the

innovation. We hope to be able to share

National Centre for Population Health and

NHS.”

this in a way that other schools might use

Wellbeing Research.

to enhance mental health and wellbeing

Dr Maria Palmer, Director R&D Forum, said:

outcomes. We plan to track the diffusion of this approach by using information collected routinely through the School Health Research Network, of which Monmouth Comprehensive is a member.

“We are delighted to have secured such a

“We’re all equal here. Staff or students. We’re all the same.”

– student

fantastic venue for the 2018 Annual Forum.

We are grateful to Health and Care Research Wales who have provided tremendous support to us to enable us to bring the Annual Forum to Wales in 2018.”

And it all feeds nicely into the Wellbeing of Future Generations Act (Wales) 2015. The

Keep up to date with information about the

Act is about improving the social, economic, environmental and cultural well-being of Wales. Specifically, in this context, “A society in which people’s physical and mental wellbeing is maximised and in which choices and behaviours that benefit future health are understood.” That’s an inspiring vision and one that will take commitment and innovation to achieve.

The project was supported by a grant received through the Institutional Strategic

2018 Annual Forum, including when the call

“They get down to your level, they don’t stand at the front and say, ‘I’m your teacher, you’ve got to respect me’, they’re not pushy. They (help) you to realise what you’re doing wrong and how you can (sort it out).” – student

Support Fund (ISSF) at Cardiff University, which is funded by the Wellcome Trust.

Collaboration between PRIME and DECIPHer

24

Health and Care Research Wales Magazine - Issue 02 - June 2017

for abstracts and bookings open here: www.delegant.co.uk/2018rdf

Combating teenage inactivity A project to assess whether giving teenagers vouchers to spend on activities of their choice can improve their health launched earlier this year at Swansea’s Limitless Trampoline Park.

The ACTIVE project, which is being carried

receive £20 per month in vouchers, for 12

out by a team of researchers based at the

months, to spend on physical activities of

Farr Institute, Swansea University Medical

their choice. The other four will act as a

School, will involve eight secondary schools

comparison group and will continue as usual,

in Swansea, and around 1,000 pupils aged

but will receive a fully-funded mindfulness

13 to 14.

course for pupils or teachers as a thank you for taking part.

The project, funded by the British Heart Foundation, aims to see whether giving

Both groups will take part in data collecting

teenagers vouchers to spend on activities of

exercises, measuring fitness, motivation

their choice can reduce the time spent being

and heart health and pupils will wear an

sedentary, improve fitness, lower the risk of

accelerometer device to record activity

heart disease and improve general health.

levels.

The ACTIVE project follows on from an earlier

Professor Sinead Brophy, a principal

study, where children in a Swansea school

investigator from the Farr Institute at

were given vouchers to spend on sporting

Swansea University Medical School, said:

activities.

“This project is trying to examine how we might help teenagers be more active

The study found that Year Nine pupils who

and how being active affects educational

received the vouchers had improved attitudes

attainment, social relationships, and the

to physical activity, increased socialisation

health, fitness and wellbeing of the pupils”.

Physical inactivity is one of the most important issues in public health today.

Studies have indicated there is a decline in physical activity in adolescence.

Research has shown that physical activity can control weight, reduce stress and even result in a higher IQ.

with friends and improved fitness and physical activity.

All schools involved will receive a

Four schools taking part in the project will

report on the outcome of the study with

Follow the ACTIVE project on Twitter:

recommendations for future interventions.

@ActiveProject_

Health and Care Research Wales Magazine - Issue 02 - June 2017

25

International Clinical Trials Day 2017 The contribution of 24,000 people who took part in part in research in Wales last year was celebrated on 20 May.

cancer to cognitive behavioural therapy.

Events to celebrate International Clinical Trials Day took place across Wales, including a ‘satsuma tour’ by the Welsh Ambulance Service Trust, and a public-facing event at the

International Clinical Trials Day marks the day James Lind started his first ever clinical trial on board the HMS Salisbury in 1747.

The naval surgeon took 12 men with scurvy, divided them into six pairs and experimented with different remedies. The two treated with citrus fruits made an impressive recovery.

The experiment not only cured two men of scurvy, but paved the way for the discovery of the health and social care advances we’re all

26

One of the easiest ways people can get involved in health and social care research is by registering for HealthWise Wales.

familiar with – from effective treatments for

Waterfront Museum in Swansea.

Professor Jon Bisson, Director of Health and Care Research Wales, said: “Behind every effective treatment there is a person.

A person who has taken part in a study or

In the run up to International Clinical Trials

research project. Without them, we simply

Day, we launched our new animated video.

wouldn’t have the treatments we rely on. So

Aimed at members of the public who have

International Clinical Trials Day offers a great

little or no knowledge of research, the video

opportunity to thank the 24,000 people who

explains research in easy to understand

took part in research in Wales last year.

terms.

Health and Care Research Wales Magazine - Issue 02 - June 2017

Jon Bisson added: “We hope the video prompts more people to ask about health and social care research. Taking part, however big or small, gives people the opportunity to improve tomorrow’s care. That’s a powerful thing.”

International Clinical Trials Week also saw us launch our first ever Facebook page.

HealthWise Wales is a unique opportunity to be part of shaping the health and wellbeing of future generations in Wales, and help the NHS in Wales to plan for the future. Register for HealthWise Wales here:

Follow, like and share our Facebook page and YouTube channel: Facebook www.facebook.com/ResearchWales/ YouTube www.youtube.com/channel/UCKR5m1jTmj06DnECTA5XTfg

www.healthwisewales.gov.wales

Health and Care Research Wales Magazine - Issue 02 - June 2017

27

Calendar Click here for: Health and Care Research Wales events calendar

28

Aneurin Bevan University Health Board R&D conference

MediWales Connects

Tuesday 20 June Christchurch Centre, Newport

Wednesday 21 June Mercure Holland House Hotel, Cardiff

ABUHB’s eighth annual research and

An all Wales NHS collaboration conference.

development conference, with speakers

The event will highlight and showcase the

including Professor Marcus Longley,

excellent work being carried out by the

University of South Wales, and Louise Taylor,

health and care communities in in Wales.

consultant midwife.

Genetics and Genomics for the 3rd Generation

Dining with Dementia in Mind

Wednesday 21 June Jury’s Inn, Cardiff

Wednesday 21 June Scout and Guide HQ, Swansea

Join the Wales Gene Park for the second ‘3G’

The seminar will highlight the importance of

conference and discover how genetics and

the dining experience for residents in long

genomics affect our everyday lives.

term care, with a focus on dementia.

National Centre for Population Health and Wellbeing Research conference

National Social Services Conference

Monday 26 June Park Plaza, Cardiff

Join the key leaders from social care across

An opportunity to learn more about the work of

motivating speakers.

Wednesday 28 June Venue Cymru, Llandudno Wales to access inspirational, informative and

NCPHWR.

Health and Care Research Wales Magazine - Issue 02 - June 2017

Welsh Stroke Conference 04 - 05 July All Nations Centre, Cardiff

Health and Care Research Wales Conference Thursday 05 October SWALEC Stadium

One of the biggest multidisciplinary events in

Centre for Ageing and Dementia Research annual conference Tuesday 10 October Jury’s Inn, Cardiff

Wales, the conference is now in its 16th year.

Collaborate 2017 Tuesday 17 October Taliesin Arts Centre, Swansea

Wales Cancer Conference 23 - 25 November Principality Stadium, Cardiff Hosted by the Wales Cancer Network and the

Dedicated to celebrating and promoting

Wales Cancer Partnership, the conference

collaborative projects and partnerships

will bring together the professional cancer

across industry, academia, government,

community from across research and clinical

health boards and other organisations.

disciplines.

2018 NHS R&D Forum 14 - 15 May 2018 Celtic Manor, Newport The NHS R&D Forum, Health and Care Research Wales and the Health Research Authority will come together to host the 2018 annual event. Delegate bookings open later this year www.annualrdforum.org.uk/delegates

F UN D ING

Health and Care Research Wales funding scheme launch dates 2017

2018

Summer

PhD Social Care Studentship Award

Summer

PhD Health Studentship Award

September

Clinical Research Time Award 2017 Health Research Fellowship Award

September

Clinical Research Time Award 2018 Social Care Research Fellowship Award

November

Research for Patient and Public Benefit (RfPPB) Wales Research Funding Scheme - Social Care Grant Award

November Research for Patient and Public Benefit (RfPPB) Wales

Research Funding Scheme - Health Grant Award

www.healthandcareresearch.gov.wales/funding/our-funding-schemes/

Health and Care Research Wales Magazine - Issue 02 - June 2017

29

‘What is research?’

Find out how research is keeping you extraordinary Page 27

Join us on our social media channels

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Health and Care Research Wales Magazine - Issue 02 - June 2017