Page 1

Human Clinical Research Facility | 675 John Kimbrough Blvd. | Building #1542 College Station, TX 77845-4243 979/458-1498 | hcrf@tamu.edu | hcrf.tamu.edu


LEADERSHIP Richard B. Kreider, PhD, FACSM, FISSN, FACN, FNAK Professor, Department of Health & Kinesiology Director, Exercise & Sport Nutrition Lab Executive Director, Human Clinical Research Facility

Nicolaas E. Deutz, MD, PhD Professor, Department of Health & Kinesiology Director, Center for Translational Research in Aging & Longevity Director of Clinical Research, Human Clinical Research Facility


COLLABORATION OPTIONS Collaborative Grants PI’s and/or grant sponsors collaborate with HCRF researchers serving as Co-PI’s or Co-I’s on developing grant and contract proposals;

TEXAS A&M UNIVERSITY HUMAN CLINICAL RESEARCH FACILITY

obtaining IRB approval; conducting the clinical trials; data management and analysis;

The Human Clinical Research Facility (HCRF), a 23,000 square foot biomedical research facility

presenting results; and, publishing research

that was developed to provide a centralized research facility for clinical researchers to conduct

findings. IDC's are shared among Co-PI's.

human clinical research trials at Texas A&M University. The HCRF houses two primary research groups from the Department of Health & Kinesiology in the College of Education and Human Development; the Exercise and Sport Nutrition Laboratory (ESNL) and the Center for Translational Research in Aging and Longevity (CTRAL). The ESNL was developed in 1997 under the direction of Richard B. Kreider, PhD and is dedicated to study the role of exercise and nutrition on health, disease, rehabilitation and performance. The CTRAL was developed in 2006 under the direction of Nicolaas E. Deutz, MD, PhD and Marielle P. Engelen, PhD and is dedicated to the study of translational research on nutrition, exercise, and metabolism in relation to aging and the common diseases of our aging population.

Fee for Service Testing TAMU PI’s and/or external sponsors work with the HCRF directors and staff to coordinate collection of data on IRB approved independently designed, funded, and managed clinical trials on a fee for service basis.


FACILITY OVERVIEW


CLINICAL TESTING & REHABILATATION The Human Clinical Research Facility provides approximately 23,000-square-feet of new space, and includes the following: Level 1: 9,863 sq. ft. • Circuit & Group Training •

Exercise Training & Rehabilitation

Break Room

Faculty Offices

Graduate Assistants

Conference Room

Work Room

Level 2: 12,189 sq. ft. • Study Rooms •

Metabolic & Fluxomics Unit Laboratory BioBank

Metabolic Kitchen

Clinical Preparation

Nurse Station

Clinical Testing Exam Rooms - Dexa Room - REE Room -


VISION/MASTER PLANNING


RESEARCH CAPABILITIES Exercise Training & Rehabilitation Physiological Testing

Preliminary Concepts

Height / Weight Skinfold Body Composition Bioelectrical Impedance (BIA) Body Composition/Bone Density Assessment (DEXA) Dietary intake analysis (4-day) Lung function Resting Energy Expenditure ECG Stress Test Cardiopulmonary / ECG Stress Test Endurance Time to Exhaustion Test Isotonic Strength Testing Isokinetic Strength Testing Anaerobic Capacity Testing Balance/Gait Analysis Biomechanical Analyses Cognitive Function Psychosocial Assessment Clinical Research Unit for Overnight Stay Research Bedrest Studies Sleep Studies Comprehensive Wet Lab Facility for Sample Analysis Stable Isotope Tracer Metabolism Studies Anabolic Response to Food Digestion and Absorption of Nutrients Protein Synthesis/Breakdown Tissue (muscle, fat) Protein and Fatty Synthesis Metabolic Kinetic Phenotyping Using a 20 Stable Tracer Mixture Intravenous Pulse Elevation Study

Data Entry / Management Data Storage Clinical Trial Consulting

11 GREENWAY PLAZA, 22ND FLOOR, HOUSTON, TX 77046 \\ 1-800-838-7272


CONCEPT DESIGN

Project Initiation / Review IRB Submission Assistance Participant Recruitment, Familiarization, Scheduling and Enrollment Use large database of previously recruited subjects with diseases like COPD, CHF, Cancer, ASD, MCI and healthy subjects Entrance Criteria Exam by Medical Screening Phlebotomy, Biopsy, Sample Handling, and Storage IV Solution Infusions Clinical Chemistry Analysis LC-MS/MS and GC-MS/MS Analysis Biobank with 15 year of samples of human studies that received stable isotope solutions Muscle and Fat Biopsies 24 hour Nursing Supervision

*


RESEARCH SERVICES


LANDSCAPE

Level 1 Floor Plan

Level 2 Floor Plan


FLOOR PLANS


ARCHITECTURE

PBKSPORTS.com


INTERIORS


INTERIORS


ARCHITECTURE

PBKSPORTS.com


FLOOR PLANS


LANDSCAPE

Level 1 Floor Plan

Level 2 Floor Plan


RESEARCH SERVICES


CONCEPT DESIGN

Project Initiation / Review IRB Submission Assistance Participant Recruitment, Familiarization, Scheduling and Enrollment Use large database of previously recruited subjects with diseases like COPD, CHF, Cancer, ASD, MCI and healthy subjects Entrance Criteria Exam by Medical Screening Phlebotomy, Biopsy, Sample Handling, and Storage IV Solution Infusions Clinical Chemistry Analysis LC-MS/MS and GC-MS/MS Analysis Biobank with 15 year of samples of human studies that received stable isotope solutions Muscle and Fat Biopsies 24 hour Nursing Supervision

*


RESEARCH CAPABILITIES Exercise Training & Rehabilitation Physiological Testing

Preliminary Concepts

Height / Weight Skinfold Body Composition Bioelectrical Impedance (BIA) Body Composition/Bone Density Assessment (DEXA) Dietary intake analysis (4-day) Lung function Resting Energy Expenditure ECG Stress Test Cardiopulmonary / ECG Stress Test Endurance Time to Exhaustion Test Isotonic Strength Testing Isokinetic Strength Testing Anaerobic Capacity Testing Balance/Gait Analysis Biomechanical Analyses Cognitive Function Psychosocial Assessment Clinical Research Unit for Overnight Stay Research Bedrest Studies Sleep Studies Comprehensive Wet Lab Facility for Sample Analysis Stable Isotope Tracer Metabolism Studies Anabolic Response to Food Digestion and Absorption of Nutrients Protein Synthesis/Breakdown Tissue (muscle, fat) Protein and Fatty Synthesis Metabolic Kinetic Phenotyping Using a 20 Stable Tracer Mixture Intravenous Pulse Elevation Study

Data Entry / Management Data Storage Clinical Trial Consulting

11 GREENWAY PLAZA, 22ND FLOOR, HOUSTON, TX 77046 \\ 1-800-838-7272


VISION/MASTER PLANNING


CLINICAL TESTING & REHABILATATION The Human Clinical Research Facility provides approximately 23,000-square-feet of new space, and includes the following: Level 1: 9,863 sq. ft. • Circuit & Group Training •

Exercise Training & Rehabilitation

Break Room

Faculty Offices

Graduate Assistants

Conference Room

Work Room

Level 2: 12,189 sq. ft. • Study Rooms •

Metabolic & Fluxomics Unit Laboratory BioBank

Metabolic Kitchen

Clinical Preparation

Nurse Station

Clinical Testing Exam Rooms - Dexa Room - REE Room -


FACILITY OVERVIEW


COLLABORATION OPTIONS Collaborative Grants PI’s and/or grant sponsors collaborate with HCRF researchers serving as Co-PI’s or Co-I’s on developing grant and contract proposals;

TEXAS A&M UNIVERSITY HUMAN CLINICAL RESEARCH FACILITY

obtaining IRB approval; conducting the clinical trials; data management and analysis;

The Human Clinical Research Facility (HCRF), a 23,000 square foot biomedical research facility

presenting results; and, publishing research

that was developed to provide a centralized research facility for clinical researchers to conduct

findings. IDC's are shared among Co-PI's.

human clinical research trials at Texas A&M University. The HCRF houses two primary research groups from the Department of Health & Kinesiology in the College of Education and Human Development; the Exercise and Sport Nutrition Laboratory (ESNL) and the Center for Translational Research in Aging and Longevity (CTRAL). The ESNL was developed in 1997 under the direction of Richard B. Kreider, PhD and is dedicated to study the role of exercise and nutrition on health, disease, rehabilitation and performance. The CTRAL was developed in 2006 under the direction of Nicolaas E. Deutz, MD, PhD and Marielle P. Engelen, PhD and is dedicated to the study of translational research on nutrition, exercise, and metabolism in relation to aging and the common diseases of our aging population.

Fee for Service Testing TAMU PI’s and/or external sponsors work with the HCRF directors and staff to coordinate collection of data on IRB approved independently designed, funded, and managed clinical trials on a fee for service basis.


LEADERSHIP Richard B. Kreider, PhD, FACSM, FISSN, FACN, FNAK Professor, Department of Health & Kinesiology Director, Exercise & Sport Nutrition Lab Executive Director, Human Clinical Research Facility

Nicolaas E. Deutz, MD, PhD Professor, Department of Health & Kinesiology Director, Center for Translational Research in Aging & Longevity Director of Clinical Research, Human Clinical Research Facility


Human Clinical Research Facility | 675 John Kimbrough Blvd. | Building #1542 College Station, TX 77845-4243 979/458-1498 | hcrf@tamu.edu | hcrf.tamu.edu

TAMU Human Clinical Research Facility Brochure  

Overview of the research facilities, capabilities, services, and collaboration options