Page 46

scriptions a year and they were over 25 cannabis containing over-the-counter medications on the market. In 1964, Dr. Raphael Mechoulam a professor of pharmacology at Hebrew University isolated and characterized the THC molecule. Since then, cannabis is once again proving to be an extremely useful and versatile therapeutic substance. Both the medical and industrial hemp uses cannabis's many valued uses. This article will examine just one aspect of cannabis' multi-pronged medicinal targets of cannabis and autoimmune disease. It will place the medical application in the context of an overview of a better understanding cannabis, cannabinoids, terpenes, and the endocannabinoid system (ECS).

Endocannabinoid System (ECS) Plants are complicated. Coffee has 880 different molecules, tomatoes 380 mol-


ha nf-magazin . com

ecules, and cannabis is no exception. The cannabis plant has at least 512 different molecules, 113 of which are cannabinoids. Cannabinoids are 21 carbon molecules that either block or stimulate the human body’s CB1 or CB2 receptors. These receptors are part of the endocannabinoid system. This system includes at least two neurotransmitters, (2AG and Anandamide) and two enzymes, FAAH and MYGL. These enzymes help metabolize both endomean derived from inside the body and phytomean cannabinoids, which stem from plants. The ECS interacts with other neurotransmitters such as dopamine and dopamine transporters to help generate important effects to help us be healthy. The CB1 receptors are found largely in the brain and the CB2 receptors are found largely in the immune system. The endocannabinoid system is arguably the largest neurotransmission system in the human brain. It is central to homeostasis and is important in modulating the speed of neuro-

Profile for Hanf Magazin

Hanf Magazin | Ausgabe 05