CHEMISTRY 332. (3) MEDICINAL CHEMISTRY. A study of pharmacologically active compounds with emphasis on chemical structure, mode of action, and the relationships of these factors to therapeutic effects in humans. The major classes of drugs discussed are various central and autonomic nervous system agents, cardiovascular agents, diuretics, antibiotics, and antineoplastic agents. Prerequisite: Chemistry 231 or consent of the instructor. Offered: staff permitting. CHEMISTRY 335. (3) BIOCHEMISTRY. An introductory survey. Emphasis is placed upon the application of basic principles of chemical structure, conformational analysis, mechanism, and dynamics to molecules and reactions of importance in living systems. The principal focus is at the molecular level. Proteins are covered extensively, and attention is also given to carbohydrates, lipids, and nucleic acids. Students who have received credit for Biology 311 may not receive credit for Chemistry 335. Prerequisites: Chemistry 231 and Biology 110 and 151, or consent of the instructor. Offered: fall semester of even-numbered years. (Cross-listed as Biology 311 in the fall semester of odd-numbered years.) CHEMISTRY 336. (3) BIOCHEMISTRY II. An extension of the topics in Biochemistry I (Chemistry 335, cross-listed as Biology 311). Topics include metabolic mechanisms, molecular signaling, bioinformatics, DNA, RNA and proteins biosynthesis, the molecular basis of the senses, and the chemical operation of the immune system. Extensive use is made of international databases, molecular visualization, and evaluation methods. Prerequisite: Chemistry 335 or Biology 311. Offered: spring semester of even-numbered years. CHEMISTRY 340-341. (3-3) PHYSICAL CHEMISTRY I, II. The theoretical principles of chemistry are developed and used to explain selected chemical phenomena. Chemistry 340 considers thermodynamics, statistics, and kinetics; Chemistry 341 considers introductory quantum mechanics and statistical mechanics. Prerequisites: for Chemistry 340, Chemistry 110 and Mathematics 142; for Chemistry 341, Chemistry 340. Corequisite: for Chemistry 340, Physics 131. Offered: 340 in the fall semester; 341 in the spring semester.
CHEMISTRY 342. (3) PHYSICAL CHEMISTRY III. The quantum mechanics introduction of Physical Chemistry II is extended to molecular systems and used in the prediction of chemical and spectroscopic properties. The theoretical basis of spectroscopic techniques is examined. Prerequisite: Chemistry 341. Offered: spring semester, staff permitting. CHEMISTRY 420. (3) ADVANCED INORGANIC CHEMISTRY. Basic theoretical concepts of inorganic chemistry applied to the principles of inorganic synthesis, and introductory organometallic and bioinorganic topics. Prerequisite: Chemistry 340. Offered: spring semester. CHEMISTRY 440-441. (3-3) CHEMICAL INSTRUMENTATION AND ANALYSIS. Principles of instrumental chemical investigation and analysis, and analytical methodology. Topics include basic concepts of electronics applied to chemistry; introduction to analog and digital signal enhancement techniques; computer-assisted acquisition, manipulation, and presentation of data; survey of spectroscopic, electrochemical, mass spectrometric, and chromatographic methods of analysis. Prerequisite: Chemistry 341, or consent of the instructor. Offered: 440 in the fall semester; 441 in the spring semester. TECHNIQUES TRACK CHEMISTRY 151-152. (1-1) TECHNIQUES OF CHEMISTRY. An extended project involving the independent synthesis and analysis of a coordination compound, requiring the use of library facilities, volumetric and gravimetric techniques of quantitative analysis, and introductory spectroscopic techniques. Two second-semester projects identify unknown compounds using chemical and spectroscopic techniques. Breakage deposit: $35.00. Prerequisite: Chemistry 151 for 152. Corequisite: Chemistry 103 or 110. Offered: 151 in the fall semester; 152 in the spring semester.