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NutraNews ISSUE 22

We

NutraNews™ ISSUE 22

Ingredient of the Month The company behind Recent ingredients

September 2011

enable the reduction of statin consumption. CardiaBeat is ideal for incorporation into 2011 dairy September products, due to its healthy market image and the natural presence of fat, which can be substituted or augmented by the ingredient. Its use in food applications has just been launched in Europe, which has thus far been the focus of

Ingredient of the Month

Regulatory Updates

Top 20 September

Industry News Letter of the Month – Super Seeds

Contact

This month’s high scorer within the Nutrafiles benchmarking system on market ® penetration is: BENEO’s inulin. Orafti inulin is extracted from chicory roots and is composed of glucose and fructose chains. Inulin has good solubility and an excellent taste profile. ® Orafti inulin can be used to replace fat and sugar and to increase the dietary fibre content of food and drink products. It is especially suited for use in dairy, bakery and cereals, confectionery, beverages and baby food products. Many food producers also use inulin in their products to enhance the fibre content, improve the texture, increase calcium absorption from a diet and for its prebiotic effect and the influence it has on digestive health. The ingredient has a wide spread market penetration due to its diversity in many types of applications, which has been further exploited by various qualities designed for particular application areas. Recent development is ® ® Orafti L58 (liquid and organic), produced from organic sugar. Orafti L58 Organic offers customers outstanding technological and nutritional properties, as a prebiotic fibre to promote good digestive health, but can also be used to replace sugar in a multitude of applications. Orafti® inulin, a range of products ®

Orafti ST-Gel

Instant-gel forming

®

Orafti HPX

HP for high temperature processes ® ® Orafti GR Orafti LGI Granulated Low sugar inulin ® ® Orafti HP Oraft HSI High-performance High soluble inulin ® Orafti Synergy1 oligofructose-enriched inulin for calcium absorption claims

The ingredient is found in about all food & drink applications: beverages, confectionery, bakery, cereals, dairy, baby food, supplements and many more.

Enzymotec's investments. Published and Powered by: NUTRAFILES® -a division of Canadean Ltd

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NutraNews ISSUE 22

September 2011

The Company Behind

B

ENEO-Orafti Head Quartered in Tienen, Belgium, operates in more than 75 countries and has production units in Oreye (Belgium), and Pemuco (Chile). BENEO-Orafti is part of BENEO; a division of the Südzucker Group, this division employs almost 900 people and has production units in Belgium, Chile, Germany and Italy. Operating entities BENEO-Orafti

Production companies

Tienen, Belgium (HQ) Singapore, Singapore Barcelona, España Saõ Paulo, Brazil Morris Plains, New Jersey, USA

Oreye, Belgium Pemuco, Chile

BENEO’s product portfolio consists of functional ingredients with nutritional and technical advantages, derived from chicory roots, beet sugar, rice and wheat. BENEO is the ideal partner to help improve the health, taste, texture and nutritional value of a product. Through a unique chain of expertise, including the BENEO-Institute, BENEO actively supports industry partners in the development of more balanced and healthy food products. BENEO-Institute: The Institute aims to advise customers and partners, reaching from ingredient approvals, physiological effects and nutritional composition to communication and labelling. As such, customers can benefit from the latest research in nutritional science and advice on claims and other regulatory affairs topics that range from prebiotics over functional sugar to rice derivates. The key nutritional topics that will form the basis of the BENEO-Institute’s work include weight management, digestive health, bone health, physical and mental performance, the effects of a low glycaemic diet in the context of healthy eating and disease prevention as well as dental health.

BENEO-Technology Center: The Center brings together BENEO’s long-standing food application and technical expertise to enhance and encourage product innovation. As such it complements BENEO’s chain of expertise providing customers with specialist advice to tackle technical questions in product development and formulation.

BENEO’s core competencies  Ingredients from nature  Health, Nutritional and Technological benefits  Product development & application technology  Market & consumer research  Concept development  Nutritional science & regulatory support through BENEO-Institute More Information: www.beneo.com

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NutraNews ISSUE 22

September 2011

Recent Ingredients Ageing

Cognitive Nerves

Glycosann SOL OxyPhyte Ultra blend

&

General Nutrition

Rhosavin 100 MEGANOL EPA&DHA

ClearSweet corn syrups Cleardex corn syrups Isosugar IsoClear high fructose corn syrup Satin Sweet 65% high maltose corn syrup

Growth

MagGran MC

Gut Health

Orafti Oligo-fructose

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Heart Circulatory

&

Stelessterol Tensio Control Pomega3 Aqua 10 Omelife Smooth FUXIONS OxyPhyte Blueberry Extract MagGran DC Megapex

Immune

OxyPhyte grape concentrate OxyPhyte Grape Skin 10% Resveratrol Graviola Licorice Series Lalmin Se

Performance& Sport

Hyvital Whey CMA 500 Hyvital Wheat Glutamine PA G4 Syrup Clintose maltodextrin

Reproductive

Testoterone Advantage

Skeletal & Joint

PrimaFlex Glycollagen Glycopure Glucosamine Sulphate 2KCL Chondronat Co-Joint Chondroitin K2Vital MagGranCC


NutraNews ISSUE 22

Skin Oral

Weight Management Metabolism

OxyPhyte Grape Seed Extract OxyPhyte White Tea Extract AquaCacteen

&

September 2011

Basic Profiles In future the Nutrafiles Ingredients database will be extended with general food grade ingredients for that purpose a category named General Nutrients are being implemented as part of the system.

Volactive UltraWhey 90 D-xylose CTR Fructofin C Fructopure Krystar Orafti Inulin OxyPhyte Yerba Mate Polyphenols OxyPhyte Green Tea Extract SteviaCane Chrominex3+ Green Coffee Bean NEOSORB- Sorbitol Powder NEOSORB- Sorbitol solution ChitoClear

September Regulatory Updates Vitamins D DSM Nutritional Products Europe AG, has recently got an EFSA expert opinion for a health Claim related to Article 14 of Regulation (EC) No 1924/2006. The EFSA Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on the scientific substantiation of a health claim related to vitamin D and risk of falling.

The Panel considers that the following wording reflects the scientific evidence: “Vitamin D may reduce the risk of falling. Falling is a risk factor for bone fractures”. The Panel considers that, in order to obtain the claimed effect, 800 I.U. (20 μg) of vitamin D from all sources should be consumed daily. The target population is men and women 60 years of age and older

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Tripeptide IPP VPP Valio Ltd, Finland, had submitted a proposed health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 to the EFSA Panel on Dietetic Products, Nutrition and Allergies. The panel was asked asked to deliver an opinion on the scientific substantiation of a health claim related to isoleucyl-prolyl-proline (IPP) and valyl-prolylproline (VPP) and maintenance of normal blood pressure (BP). The Panel concluded that a cause and effect relationship has not been established between the consumption of IPP and VPP and maintenance of normal blood pressure.

September 2011

In weighing the evidence, the Panel took into account that 13 of the human intervention studies provided, four of which were adequately powered to detect small betweengroup differences in SBP, did not observe an effect of IPP and VPP on SBP or DBP; that the interpretation of the results from seven out of the eight studies which reported an effect of IPP and VPP on office SBP was hampered by major methodological limitations; that the animal studies did not provide additional information on the effect of IPP and VPP on BP in humans; and that there is no convincing evidence for a mechanism by which IPP and VPP could exert the claimed effect at the proposed dose.

Top 20 in September Health Area IPR Novelty Regulatory Market Biology Action

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NutraNews ISSUE 22

Industry News

September 2011

MYR0.51 ($0.178) per shares payable in full upon acceptance.

Nisshin OilliO to acquire Industrial Quimica The Nisshin OilliO Group, Ltd., a Japanese manufacturer and seller of edible oils, has entered into a stock purchase agreement to acquire 85% stake in Industrial Quimica Lasem, S.A., a manufacturer of chemicals for cosmetic industry, from Josep Betriu Pi, Josep Marti Pellise and Mercapital, S.L. for a consideration of EUR26 million ($36.71). Both Industrial Quimica and Mercapital are based in Spain. Mercapital operates as a private equity firm. Nisshin OilliO also holds a right to acquire remaining 15% stake in Quimica Lasem. Edme to form joint venture with Cerex Edme Limited, a UK-based producer of ingredients for the baking, cereal and food industries, has agreed to form a joint venture with CereX BV, a Netherlands-based producer and seller of natural cereal extracts, to distribute malt extracts in the UK and in Europe.

The shares have been paid on the basis of one rights share for every two existing ordinary shares of MYR0.50 ($0.17) each held in KFM together with up to 37,168,725 new free detachable warrants on the basis of three warrants for every two rights shares subscribed. AFFIN Investment Bank Bhd. is acting as a merchant banker to KFM on the transaction. WILD Flavors to acquire assets of A.M. Todd Company WILD Flavors (Schweiz) AG, a Swiss manufacturer of natural ingredients for the food and beverage industry, has reached an agreement to acquire certain assets of A. M. Todd Company, a US-based provider of mint flavours and ingredients. The transaction is expected to complete by October 31, 2011. Biothera partners with United Pharmacopeial Convention (USP)

States

Cargill to form joint venture with Grupo USJ

The United States Pharmacopeial Convention (USP) has entered into a collaboration agreement to develop a monograph for beta glucan from baker’s yeast with Biothera, a developer of health ingredients for functional foods and beverages, nutritional supplements, cosmetics and animal nutrition products. Both companies involved in the transaction are based in the US.

Cargill, Incorporated, a producer of food, agricultural, financial and industrial products and services based in the US, has entered into a joint venture with Grupo USJ, a Brazilian producer of sugar, ethanol and bioelectricity.

USP is a scientific non-profit organization that sets standards for the quality, purity, identity, and strength of medicines, food ingredients, and dietary supplements manufactured, distributed and consumed worldwide.

SJC Bioenergia is a new 50-50 joint venture company formed which combines industrial assets of Grupo USJ and other mills.

Biothera contributed the reference standard and two methods for identifying and quantifying the beta 1,3/1,6 branched glucan polymer derived from the cell walls of baker’s yeast as well as additional methods to assure the purity of the material.

Edme will combine the production, packaging and distribution capabilities with CereX. It has also invested GBP0.35 million ($0.54 million) in a new packaging facility

In addition to sugar and ethanol, SJC Bioenergia will also generate electricity from sugarcane baggage. Kuantan Flour Mills announces rights issue of 24.78 million shares Kuantan Flour Mills Bhd. (KFM), a Malaysian producer of wheat flour, pre-mix and trading products, has agreed to issue up to 24.78 million shares of MYR0.50 ($0.17) each at an issue price of

Viocare acquires DSM Personalized Nutrition from Royal DSM Viocare, Inc., a provider of wellness and nutritionbased systems, has acquired DSM Personalized Nutrition LLC, a provider of whole-health wellness services, from Royal DSM N.V., a Netherlandsbased life sciences and material sciences company.

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Viocare and DSM Personalized Nutrition are based in the US. Pursuant to the transaction, DSM will remain involved in the business as a minority shareholder in Viocare through DSM Venturing. Kerry agrees to acquire SuCrest Kerry Group plc, a UK-based provider of food ingredients and flavours for the food and beverage industries, has entered into an agreement to acquire Sucrest GmbH, a German provider of sweet ingredients to the bakery, ice-cream, confectionery, cereal and snack sectors. The transaction is expected to be completed by December 31, 2011. Olam International plans to acquire Vallabhdas Kanji Olam International Limited, a Singapore-based company engaged in supply chain management of agricultural products and food ingredients, is planning to acquire Vallabhdas Kanji Limited (VKL), a processor of spice and spice ingredients, from The J. V. Mariwala Group, a company engaged in the business of food ingredients, spices and spice extraction. Both VKL a

September 2011

nd J.V. Mariawala are based in India. Global Sweeteners Jincheng Corn

to

acquire

Changchun

Global Sweeteners Holdings Limited has entered into a sale and purchase agreement to acquire the entire issued share capital of Changchun Jincheng Corn Development Co., Ltd., a Chinese whollyowned subsidiary of Global Bio-chem Technology Group Company Limited, a manufacturer and seller of corn refined products, for a purchase consideration of HKD510 million ($65.44 million). Both Global Sweeteners and Global Bio-chem are based in Cayman Islands.lobal Sweeteners is a manufacturer of corn based refined and sweetener products, while Changchun Jincheng is a corn refinery plant with a processing capacity of 600,000 metric tonnes per annum. The consideration will be satisfied upon completion of the acquisition by Global Sweeteners allotting and issuing to Global Bio-chem 377,778,000 new shares at an issue price of HK$1.35 ($0.17) per consideration share. Upon the issue and allotment of the consideration shares, Global Bio-Chem’s shareholding in Global Sweeteners will increase from 52.23% to 64%.

Letter of the Month Super seeds for heart and performance Karin Elisa Nielsen, Division Director Nutrafiles, Canadean Ltd

As an ingredient, cocoa beans are found in numerous food and beverage products and support the most important demands from modern consumers; - indulgence, health support and performance booster. What more do we need? The seeds from the tropical tree Theobroma cacao L, were initially traded by the Mayans (200 BC until 1500 AD) to the Aztecs, who used them in drinks and various dishes. Today cocoa is consumed mainly as a confectionary or drink flavouring. When properly sweetened, cocoa’s flavour pleases most consumers. However, the sugar is a concern; recently it was announced that a naturally sweetened, tooth friendly chocolate containing stevia would be launched in UK, early in 2012. Also, Barry Callebaut’s recent consumer survey revealed

that 1 in 3 Europeans wants chocolates with health benefits and 4 in 10 want a reduced sugar content. On the other hand, perhaps consumers are getting used to the bitter taste, as they recognise dark chocolate to be healthier, and the consumption grows faster today representing up to 40% market

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NutraNews ISSUE 22

related to cognitive functions and exerting increasing energy and alertness. However, any potent effect may not be expected from normal consumption, whereas studies show that encapsulated or inhaled cocoa may give other results. Interestingly, caffeine has just been granted an EFSA health claim on alertness– could cocoa be next? It definitely has the reputation of being a mood food. Additionally many essential nutrients are found in rich measures in cocoa, as essential minerals: potassium, calcium, magnesium, iron and zinc. 300 mg/100g or ml

share in major markets. Ancient cocoa drinks were different - bitter strong drinks that probably were more like coffees and teas. These bitter notes come mostly from the various polyphenols present in cocoa. Modern biotechnology has identified that processing, as well as crops, may influence the content of bio actives. More than 10% of flavanols by weight are found in the cocoa mass. Flavanols are also the main subject of interest for the cocoa health and nutritional science. The highest flavanol content is in the dark chocolate. Clinical studies confirm that dark chocolate in comparison with milk or white chocolate exerts the healthy heart benefits. Clinical data from chocolate studies has been various, but unfortunately very biased due to the fact that blind studies are difficult – the testers are too accustomed to chocolate and can effortlessly identify chocolate to a placebo. The healthy heart benefits are partly attributed to the potent antioxidant capacity of cocoa flavanols as studies have shown that high consumption populations produce more nitric oxide than low consumption groups. The flavonoids, or more specifically the flavanol, epicathecin, has been demonstrated to increase blood capillary widening (vasodilatation) and this is regulated specifically by nitric oxide. Healthy heart benefits are further substantiated by studies on blood pressure in normal healthy subjects. By consumption of dark chocolate, systolic blood pressure was significantly reduced, and still was by 5% for eight weeks after trials ended. In a meta-analysis the blood pressures were reduced 4.7 mm (systolic) and 2.8 mm (diastolic) as compared to non-cocoa consuming controls. Another health benefit related to heart health is the cholesterol and blood triglyceride lowering effect of dark chocolate, which recently has been scrutinised in a meta-analysis of science from 10 studies verifying that dark chocolate indeed, had a significant reduction of LDL cholesterol and total cholesterol. Good news is that the active dose seems to be lower than 500 mg a day, and some supplementation studies favour approximately 300 mg – allowing a beneficial effect on consuming 100g of quality dark chocolate per day – or using ingredients as Acticoa and Cocanox offering increased bioavailability and standardised high levels of flavanols. Cocoa also contains anadamines, caffeine, theobromine, and phenyletylamine, all compounds

September 2011

250 200 150 100 50 0 Dark Milk Chocolate Chocolate Chocolate milk

Figure 1. Cocoa Polyphenol contents

Flavanols

Flavonols

Hydroxycinnamic acids

Stilbenes

Main Sources:

   

INRA – Polyphenol-explorer Shroeter et al. Proc Natl Acd Sci 2006 Taubert et al. Arch Int Med 2007 Tokede et al. Eur J J Nutr 2011

Contact Information Canadean Ltd www.nutrafiles.com

Tel.: +44 (0)1256 394 200 info@nutrafiles.com Nutrafiles@anadean.com

Disclaimer: Reasonable care has been taken in preparing this document and the information provided herein is believed to be accurate. However, this information is not reviewed by any authority as EFSA or FDA.

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NutraNews | September 2011