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Antimicrobial cables and systems for medical technology Demanding applications – hygienic solutions

The Quality Connection


A new, highly effective technology for anti­ microbial treatment of cable surfaces Microorganisms are the cause of numerous infections in hos-

This is the basis for a highly effective technology with the help

pitals (nosocomial infections) [1]. Millions of people worldwide

of which LEONI can add antimicrobial [6] treatment [7] to cable

are infected with multi-resistant germs – many people also die

surfaces. In line with the Lewis acid-base theory, acid ions are

of this cause in Europe [2]. These infections stem from contami-

released that lower the pH level only on the boundary surface.

nated materials; especially plastic surfaces near patients [3] such

This reaction causes a disruption of the sensitive pH balance

as medical devices (e.g. ECG, ultrasound, endoscope) and their

of the microorganisms. Cell functions are compromised and

cables [4]. According to a study, 77 % of ECG cables are popu-

separation is restricted; the cell is weakened and ultimately dies

lated with antibiotic-resistant pathogens [5].

off. This antimicrobial effect can be microbiologically proven. Furthermore, because of its median grain size of > 1μm, the

The growth of germs depends on the pH level. Like the skin’s

oxide does not come under the controversial nanotechnology.

acid protective layer, a pH level of < 4 also prevents bacteria from settling on a plastic surface.

strong acid

0 pH-level

efficiency scope

neutral

4

7

strong alkaline solution

14


Verifications

Reference list:

Quality-Labs BT has verified the effectiveness.

[1] Gastmeier Petra; Nosocomial infections in Germany: “What are the numbers, based on the estimates for 2006”;

HygCen carried out medical testing pursuant to DIN EN ISO

Dtsch Med Wochenschr (2008); issue 133; 1111-1115

10993-5 and 10993-10.

[2] Jean-Louis Vincent; Nosocomial infections in adult intensive-care units; The Lancet; 361 (2003); 2068-77 [3] Kerri A; Environmental contamination because of multidrug-resistant Acinetobacter baumannii surrounding colonized or infected patients; American Journal of Infection Control (2011) Volume 39, Issue 9, Pages 711-715 [4] Donna Quinton Brown; Electrocardiography Wires: A Potential Source of Infection; NTI News Section B; 106 (2006) [5] Jancin Bruse; Antibiotic resistant Pathogens found on 77 % of ECG lead wires; Cardiology News; 2 (2004); 14 [6] Test report of QualityLabs BT GmbH [7] Zollfrank Cordt et al.; Antimicrobial activity of transition metal acid MoO3 prevents microbial growth on material; Materials Science and Engineering: C; (2012), 47-57 [8] Test report of HygCen GmbH

LEONI provides these benefits: ■■

■■

■■

A new, highly effective antimicrobial mechanism for

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No induction of resistances

plastic surfaces

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Reduction in adherence, thereby less biofilm formation

Biocompatible in accordance with DIN EN ISO 10993-5

■■

Lasting reduction in germ load

and 10993-10 [8]

■■

Risk of infection is lowered

No deactivation during use due to hand perspiration

■■

Hygiene is improved and overall costs reduced

or proteins ■■

Reduces the germ load also of e.g. MRSA, VRE and ESBL

Germ load General hygiene

Hand disinfection staff

high

An antimicrobial surface can contribute significantly to reducing the germ load, increasing the hygiene standard and minimising the risk of infection.

Antimicrobial surface

Immune system

low


0h

3h

6h

9h

12h Staphylococcus aureus MRSA ATCC 25923

Escherichia coli ATCC 27020

Pseudomonas aeruginosa ATCC 10145

Test description

Note regarding the test method

The test specimen (an approx. 4 cm long section of cable) is

The findings obtained with this method correspond to the

incubated with 109 CFU*/ ml for six hours. Thereafter the test

results of tests in practice, involving various timeframes and

specimen is wound across a blood agar plate, which is incubated

concentrations on the surface. A significantly faster reduction is

at 37 °C, every three hours.

evident in the case of a minor germ load. This method describes

*(CFU = colony-forming units)

not only the biostatic and biocide effect in planktonic condition, but also assesses the adherence and the biofilm formation of the germs. Blocking these is the key to eliminating germs on the

Analysis of the photographic documentation

surface.

A significant reduction in germs is evident after 3 hours. Subsequently, after 6 to 12 hours (depending on the germ), there are

LEONI is also backed in this by the findings of an accredited

no pathogens left on the cable surface.

laboratory, which applied a recognised, quantified measurement method [6]. A substantial reduction of germs of > 99.99 % is already achieved when adding a small measure of the oxide. The antimicrobial effect is also maintained during normal handling (affected by perspiration or protein) at different times and

Tested germs

in various concentrations.

Escherichia coli

ATCC 25922

Enterococcus faecium

ATCC 29212

Staphylococcus aureus (MRSA)

ATCC 25923

Staphylococcus epidermidis

ATCC 700562

Streptococcus spp.

ATCC BAA 1413 59650

Pseudomonas aeruginosa

ATCC 10145

Klebsiella pneumoniae

ATCC 10872

Candida albicans

ATCC 90028

Proteus mirabilis

D. Stickler, Birmingham

Enterobacter cloacae

ATCC 19336

Biological risk assessment There is no evidence of any side effects like toxicity, allergies and irritation pursuant to DIN EN ISO 10993 on the human skin [8].


Antimicrobial cable solutions – Made by LEONI As one of the world‘s leading manufacturers of special cables and cable systems for medical technology, LEONI exclusively provides its customers with an extensive portfolio of products for sophisticated applications in line with the respective requirement profile. In principle, any solution can be antimicrobial-treated regardless of the intended application.

Our product portfolio Cable

Applications Diagnostics

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Hybrid cables

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X-ray

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Catheter technology

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Fiber optic cables

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Mammography

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Intracorporal systems

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Measurement and control cables

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Computer tomography

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Extracorporal support systems

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Coaxial and high-frequency cables

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Magnetic resonance tomography

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Dental technology

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Data cables

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Ultrasound / sonography

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Miniature cables

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Molecular imaging / nuclear medicine

Patient monitoring

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Flat cables

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Endoscopy

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ECG, EEG & MEG

■■

Wires and strands

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Catheter technology

■■

Oxygen saturation

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ECG, EEG & MEG

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Blood pressure

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Laboratory technology

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Temperature

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Dental technology

Cable systems ■■

Cable harnesses and systems

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Pre-assembled cables

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Cable routing systems

Therapy

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Safety cut-out sensor

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Radiotherapy

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Laser medicine

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High-frequency surgery

Fibers & laser probes ■■

Fiber bundles

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Robot and computer-assisted surgery

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Laser probes

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Laparoscopy


LEONI Kabel GmbH Business Unit Healthcare

Stieberstrasse 5 D-91154 Roth Germany Phone +49 (0)9171-804-2266 Fax

+49 (0)9171-804-2199

www.leoni-healthcare.com


Antimicrobiële kabels en kabelsystemen