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Duke Anesthesiology Newsletter :: Tuesday, June 25, 2013

Tuesday, June 25, 2013 • Volume 15, Issue 24

Resident Graduation Wrap-Up By Irene Kontje On Saturday, June 22, 2013, the Department celebrated the graduation of fourteen residents at Hope Valley Country Club in Durham. The graduating residents are Drs. Brian Barrett, Miles Berger, Liz Crafts, Christy Crockett, Tori Dallas, Bola Faloye, Jason Guercio, Liz Malinzak, Cory Maxwell, Jeff McKenzie, Jacob Nadler, Quinton Quinones, Shannon Tew and Darrell Wilcox. Read online.

A Friday Farewell to Dr. Katherine Grichnik Dr. Katherine Grichnik will be retiring from the Duke University School of Medicine on June 28th, 2013. She will be moving to Florida and will be assuming a new role as Director of research, education and quality for American Anesthesiology, a division of the Mednax National Medical Group. For her administrative roles, Dr. John Sundy of Rheumatology is the new Director of the DCRI’s Center for Educational Excellence and Dr. Chitra Subramaniam has been named Assistant Dean for CME in the School of Medicine. Although transitions are hard, Dr. Grichnik is both delighted and grateful to have been a part of Duke Anesthesia for 22 years – She is incredibly proud to have been a member of a Department marked by quality, skill and dedication of all aspects of clinical, research, education and administrative work - Duke Blue will always be with her! She can be contacted at the following email and phone numbers: kgrichnik@gmail.com or katherine_grichnik@americananesthesiology.com (after August 19th) Work: 954-384-0175 Cell: 919-612-3682

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Duke Anesthesiology Newsletter :: Tuesday, June 25, 2013

DREAM Innovation Grant (DIG) Update The DREAM Innovation Grant (DIG) supports innovative high-risk, and potentially high-reward investigations to accelerate anesthesia and pain management research. Our goal is to raise $90,000, which will allow us to fund at least three $30K DIG recipients in 2014. The winners of this grant will be announced in October 2013. To date, we have raised $41,305 towards our goal!

2014 DREAM Innovation Grant (DIG) Application Announcement The DIG supports innovative high-risk, and potentially high-reward investigations to accelerate anesthesia and pain management research. Research deemed innovative may introduce a new paradigm, challenge current paradigms, look at existing problems from new perspectives, or exhibit other uniquely creative qualities. The DIG promotes new ideas; therefore, proposals need not include preliminary data. However, a solid rationale for the work must be provided. A maximum of $30,000 will be awarded to each recipient. None of the funds awarded are to pay for faculty salary or overhead expenses. The number of grant recipients and grant amount will be determined by the DREAM Innovation Grant Committee after all applications have been received. Please note that you must be a faculty member to apply for a DIG grant. Application and Deadline Applications and questions should be submitted to David S. Warner, M.D. at david.warner@duke.edu. 1. A Statement of Intent (Deadline August 1, 2013): a. Abstract (150 word max) b. Budget (Budgets should not include salary support for a faculty, resident, or fellow) c. NIH formatted Biosketch (PI only) 2. NIH R03-like Application Format (Hard Deadline September 2, 2013): i.e., up to 1 page for Specific Aims and up to 6 pages for the research plan (background, preliminary data and/or rationale, experimental plan, description of roles of scientific team members, timeline for milestones and completion, and a detailed definition of plans to advance work beyond this funding interval). A major criterion for funding will be the plan for and likelihood of follow-on extramural funding resulting from this project. All pages are to be single-spaced in 11 point Arial font. Appendices will not be considered. Final applications must be submitted as a single pdf document and include the final abstract, budget, biosketches of key personnel, specific aims, and research plan.

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Duke Anesthesiology Newsletter :: Tuesday, June 25, 2013 3. All complete submissions will undergo review and selection by the Senior Research Council. Written critiques will be provided to the applicants. 4. Winners will be announced October 13, 2013 during the ASA Alumni Reception in San Francisco.

Vouchers for Data Management Using the Pedigene Informatics System From: Sally Kornbluth, Ph.D., Vice Dean for Basic Research OVERVIEW:   As very large datasets become more common in biomedical research, we want to ensure that School of Medicine investigators have access to the capabilities they need to manage, analyze, report and replicate complex data. Recent advances in ‘omics and other high-throughput technologies have led to the generation of massive amounts of data, requiring implementation of complex data management processes for storing data and for enabling adequate analysis.  Replication of such analyses mandates access not only to the final data sets, but also a record of the steps performed during the manipulation of the raw data sets to produce the final set of analyzed data.  Such investigations must clearly specify each step in the handling of original source data so that others can use the same original data set to replicate the final analyses.  In addition, even for smaller datasets, where research is destined for clinical translation, it is critical that investigators have a secure system that ensures data provenance and enables storage and interrogation of data for quality assurance and analysis using validated software. The Duke Center for Human Genetics has developed an informatics system called PEDIGENE, which is designed to implement best research practices in a flexible, secure and accessible software platform. This informatics system provides a backbone to allow the flow of data from hypothesis to data analysis to integration and inference. The system can connect specialized core resources to data generation and analysis for large and small projects alike, and along the way provide the opportunity for trainees to learn in a robust software environment. The PEDIGENE system is also linked to a study implementation group, an experienced group of senior staff to work with investigators to understand software needs, research workflows and presentation of results. It is the goal of this RFA to facilitate access to PEDIGENE by basic and translational researchers seeking a robust data management.  The voucher of up to $7500 will allow initial specification and development of a study-specific or laboratory-specific informatics system in collaboration with PEDIGENE staff and members of the study implementation group. REQUIREMENTS: Applicants for funds must be Duke School of Medicine faculty members. The proposal must be accompanied by a brief note from the manager of the PEDIGENE Shared Resource (Barbara Due) attesting to the utility of PEDIGENE for the proposed application.  We recommend that faculty meet with PEDIGENE staff prior to submitting the proposal to understand the requirements and to discuss timing of the work.  PROCESS: Investigators must prepare a one-page proposal describing the informatics needs for the research project or laboratory workflow and the utility of PEDIGENE for achieving the goals of the project (11 pt font, 0.5” margins). Completed application packets (Investigator name and contact information cover page, the one-page proposal, and the letter from the manager of the PEDIGENE Shared Resource) should be sent as a single pdf file to Chris Freel  (christopher.freel@duke.edu). The deadline for submission is July 22nd, 2013.       FUNDS:  Vouchers are not renewable or transferable. The funds are provided directly to the PEDIGENE facility to cover the costs for the approved project.

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Duke Anesthesiology Newsletter :: Tuesday, June 25, 2013

AWARDS: Proposals will be reviewed by a faculty committee chaired by the Vice Dean for Basic Science. The committee will be charged with selecting proposals that will benefit substantially from the use of the PEDIGENE system. Up to ten awards will be made depending on the application pool.   Awards will be announced in early August.

Second Annual Holland-Trice Scholars Award for High Risk/High Impact Discovery Research in Brain and Disease From: Sally Kornbluth, Ph.D., Vice Dean for Basic Science Request for Proposals The Duke University School of Medicine is pleased to announce a second call for proposals for high risk/high impact research in the area of brain and disease. This RFP is focused on discovery science and priority will be given to School of Medicine investigators researching the basic biology underlying brain disease, including (but not limited to) Alzheimer’s and other neurodegenerative disorders, stroke, and behavioral disorders. Up to $50,000 for one year will be provided for pilot research projects on brain and disease based on these criteria: Originality Scientific rational Potential for scientific impact Clear articulation of the way in which the proposed research differs from other funded projects of the Principal Investigator Clarity of plans for obtaining subsequent extramural funding to extend or complete the project We expect to fund four projects during the present academic year. Grants funded during the last cycle of this award mechanism are not eligible for renewal, though previously funded investigators may apply for distinct projects.  Please include the following in your proposal: Title page and contact information Abstract of 150 words or less describing the project Project summary in 3 pages or less (11 point Arial font, inclusive of figures but not including citations), addressing the selection criteria listed above. Biographical sketches for participating faculty. Please use the “NIH Biosketch Form”  http://grants.nih.gov/grants/funding/phs398/phs398.html    Deadline: Proposals must be received by 5 PM EST, August 1, 2013 Selection Process for New Awards – Proposals will be peer-reviewed, and awards announced by October 1, 2013.  Selection of peer reviewers and final funding decisions will be made by the Dean of the School of Medicine.  Applicants will be notified of funding decisions but will not otherwise receive feedback from the evaluation process.  Awardees will be required to submit a year-end progress report and will be expected to present their accomplishments at an informal meeting towards the end of their

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Duke Anesthesiology Newsletter :: Tuesday, June 25, 2013 year of funding. Applications should be submitted as pdf files to: anne.meska@duke.edu

Request for Proposals for Interdisciplinary Colloquia 2013 From Nancy C. Andrews, M.D. Ph.D., Dean, Duke University School of Medicine & Sally Kornbluth, Ph.D., Vice Dean for Basic Science, Duke University School of Medicine OVERVIEW: The School of Medicine (SoM) is pleased to announce its third annual RFP to provide support for interdisciplinary colloquia that bring together basic science, translational and clinical faculty members with common interests in a biomedical problem or area. Interested applicants are encouraged to read about colloquia that have been funded in previous years at http://medschool.duke.edu/research/interdisciplinary-colloquia FUNDING:  Awards of up to $5,000 will be provided to support each successful proposal.  Funds can be used to cover the cost of food, meeting venue, external speakers or other meeting costs. REQUIREMENTS:  Proposals must be submitted by teams representing two or more departments, institutes or centers.  Applicants for funds must be faculty members with primary appointments in a School of Medicine department. Meetings may have any format (e.g., small monthly dinner meetings, larger quarterly meetings, other approaches), but should be designed to bring together lab-based investigators and clinicians with diverse perspectives. Preference will be given to proposals that articulate a plan to sustain interactions and/or prepare joint grant applications after the initial colloquium supported by the SoM. PROCESS:  Please send a one-page (maximum) description of the proposed colloquia, organizers and potential participants, the format of the meeting(s), plan for advertising, budget, and plan to sustain the meetings and/or organize multi-investigator grant applications after the initial funding has been used. Renewals of previously-funded colloquia will be considered, though these applicants must articulate the value added by their colloquia over the past year(s), including submitted collaborative publications and grants from colloquia participants. Applications should be sent in PDF format to Carolyn Mackman (carolyn.mackman@duke.edu) with the subject line “Interdisciplinary Colloquium Funds” by July 31, 2012. AWARDS NOTIFICATION:  Successful applicants will be informed by August 30, 2013, and will have one year from the start of funding to spend the funds.

Upcoming Major Funding Opportunities from the PatientCentered Outcomes Research Institute (PCORI) From Jill Boy As many of you know, PCORI is an independent, non-profit, non-governmental organization funded from the Medicare trust fund. Its mission and vision are described below.

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Duke Anesthesiology Newsletter :: Tuesday, June 25, 2013 Mission: The Patient-Centered Outcomes Research Institute (PCORI) helps people make informed health care decisions and improves health care delivery and outcomes by producing and promoting high integrity, evidence-based information that comes from research guided by patients, caregivers and the broader health care community.

Vision: Patients and the public have the information they need to make decisions that reflect their desired health outcomes. PCORI just came out with a series of FOAs that have quite a range of opportunity for our clinical research faculty. They include: A national network for EMR based research, including: Data research networks—these are to be EMR based integrated systems with a requirement for 1 million patients per system; 8 will be funded; Patient powered networks—these must be co-led by patient advocacy groups; multiple networks will be funded; A coordinating center for the effort—only one coordinating center will be funded. For these networks, the rules are evolving, but currently are: Each institution can be part of 2 applications for each type of network, but can only accept funding for one of each type; Individuals can be part of multiple applications; The coordinating center institution cannot be a part of a network; LOI's for the network proposals are due by June 19, 2013. There are also 5 R-01 type areas:  health systems improvement, disparities, CER methods, assessment of therapies and strategies, communication & dissemination.  These applications are entirely open with no limitation on the number of applications. An individual can be a PI on only one of these per cycle, but can be a co-investigator on an unlimited number. After many discussions with faculty, we have decided to appoint a review committee to adjudicate which applications should go in when there are a limited number allowed from each institution and to provide feedback to applicants who are not familiar with the unique criteria that will be used to judge PCORI grants. Members of the committee, configured to represent the Schools of Medicine and Nursing, the Health System and patient advocates, include: Adrian Hernandez, Gillian Sanders, Amy Abernethy, Iain Sanderson, Jeffrey Ferranti, Beth Merwin, Diane Holditch-Davis, Janet Prvu Bettger, Michelle Lyn, and Bray Patrick-Lake. If you are planning to submit a Data Research Network or a Patient Powered Network application, it is critical for you let us know right away because of the limited number of applications per institution. Please send an email to Dr. Gillian Sanders no later than Friday, June 14, 2013: Gillian D. Sanders Ph.D. Associate Professor of Medicine Duke Evidence Synthesis Group, Director Duke Clinical Research Institute Duke University Phone: 919-668-7824 Fax: 919-668-7032

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Duke Anesthesiology Newsletter :: Tuesday, June 25, 2013 Email: gillian.sanders@duke.edu

Calendar of Events Take a look at what's coming up in the Department of Anesthesiology with our all new online calendar of events. Keep up-to-date with departmental events, CME conferences, Preceptorships and social happenings.

Important Dates: 2013 ASA Meeting: October 12-16, 2013 | San Francisco, CA 25th Annual Duke Anesthesiology Alumni Reception: October 13, 2013 | San Francisco, CA Duke Anesthesiology Holiday Party December 14, 2013 | 6:30 PM - 12:00 AM | Cotton Room at Golden Belt | Durham, NC View all departmental events online.

DukeWELL Seminars FREE! Seminar Series DukeWELL (formerly Duke Prospective Health) proudly sponsors a free monthly seminar series, presented by Duke Integrative Medicine that address such topics as stress, healthy eating, meditation, movement, sleep, massage and more. Classes have limited seating and pre-registration is required.  To register Duke employees can call 919-416-DUKE (3853) or click here to register online. To find the DukeWELL seminar enter DukeWELL in the search bar under the calendar. DukeWELL monthly seminars are held on Thursdays from 5:30pm to 7:00pm at Duke Integrative Medicine on the Center for Living Campus. Upcoming dates are listed on the right under Program Information.  To find out more about the DukeWELL program, click here.

Comings and Goings in the Department Please welcome Maryam (Samila) Mohseni to the department. Samila is our new IT Director.  She joins us today, Tuesday, June 25, 2013.  Welcome aboard! Katherine Wilbur joined the department on June 10, 2013. Dionne Apedjihoun joined the department on June 11, 2013.  Dionne is a new Clinical Research

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Duke Anesthesiology Newsletter :: Tuesday, June 25, 2013 Coordinator II. Sandhya Gohimukkula started with the department on June 24, 2013. The following have left the department. We wish them best of luck on their future endeavors. Students Matthew Gray and Monroe Wolf left the department on May 31, 2013. Student Darya Cheng left the department effective June 7, 2013. Yuling Yeh, Visiting Research Scholar, left the department on June 14, 2013. Student Paige Noble left the department on June 14, 2013. Kristine Brown, Research Technician II left the department on June 20, 2013.

Let's Keep in Touch Please contact Tiffany Nickel at tiffany.nickel@duke.edu with your new mailing and email address prior to your departure so that we can add you to our database! If you haven’t already, check out our new alumni database at: http://anesalumni.duhs.duke.edu/alumni

Anesthesiology on Facebook and Twitter Do you have exciting news or information pertinent to the academic community that you want to share through the department’s social media sites? The department has Facebook and Twitter accounts for Duke Anesthesiology, Duke Anesthesiology Alumni, and the DREAM Campaign.  Send your announcements to Tiffany Nickel (tiffany.nickel@duke.edu) to be posed on the department’s social media sites.  Remember to keep announcements to 140 characters in length so that they are twitter compatible (about the size of this sentence).  Including a link to another online source for more information is highly recommended.

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