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2011 Joint SOFT-TIAFT International Conference & Exposition on Forensic & Analytical Toxicology SCIENTIFIC PROGRAM 25 – 30 SEPTEMBER 2011 MARRIOTT MARQUIS HOTEL SAN FRANCISCO, CALIFORNIA, USA


2011 SOFT-TIAFT Organizing Committee Nikolas P. Lemos

Committee Chairman & Host

Ann Marie Gordon Co-Host

Daniel S. Isenschmid Treasurer

Vina R. Spiehler

International Delegate Liaison

Marilyn A. Huestis Scientific Program

Laureen Marinetti

Workshops

Dimitri Gerostamoulos Workshops

Jeri Ropero-Miller

Sponsors & Exhibitors

Peter R. Stout Sponsors & Exhibitors

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The 2011 SOFT-TIAFT Organizing Committee wishes to acknowledge the invaluable contribution made by dozens of SOFT and TIAFT members who assisted our distinguished International Advisory Board Members with the peer-review of submitted abstracts. International Advisory Board Members

International Advisory Board Members

Dan T Anderson, MS - USA

Hans H Maurer, PhD - Germany

Robert A Anderson, PhD - UK

Manfred R Möller, PhD - Germany

Sotiris Athanaselis, PhD - Greece

Christine Moore, PhD - USA

Elisabetta Bertol, PhD - Italy

Ashraf Mozayani, PhD - USA

Jochen Beyer, PhD - Australia

Ilkka Ojanperä, PhD - Finland

Federica Bortolotti, MD, PhD - Italy

David Osselton, PhD - UK

Jennifer Button, BS - UK

Frank T Peters, PhD - Germany

Hee-Sun Chung, PhD - Korea

Simona Pichini, PhD - Italy

Marc Deveaux, PhD - France

Anya Pierce, MBA - Ireland

Olaf H Drummer, PhD - Australia

Nikolaos Raikos, MD - Greece

Simon Elliott, PhD - UK

Marina Stajic, PhD - USA

Bradford R Hepler, PhD - USA

Osamu Suzuki, MD, PhD - Japan

David W Holt, PhD - UK

Franco Tagliaro, MD - Italy

Alan Wayne Jones, PhD - Sweden

Helena Teixeira, PhD - Portugal

Sarah Kerrigan, PhD - USA

Alain G. Verstraete, MD - Belgium

Pascal Kintz, PhD - France

Robert Wennig, PhD - Luxembourg

Thomas Kraemer, PhD - Switzerland

Sarah Wille, PhD - Belgium

Robert Kronstrand, PhD - Sweden Marc LeBeau, PhD - USA

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Wednesday, 28 September 2011 2011 SOFT-TIAFT OPENING CEREMONY 08:30-08:45

OPENING REMARKS: PROFESSOR NIKOLAS P. LEMOS, CHAIRMAN & HOST

08:45-09:00

WELCOMING ADDRESS: THE HONORABLE EDWIN M. LEE, MAYOR OF SAN FRANCISCO

09:00-09:50

PLENARY SESSION: “SAN FRANCISCO IN THE 1960S: SUMMER OF LOVE AND TOXICOLOGY” PROFESSOR THOMAS E. KEARNY

09:50-10:10

BREAK

10:10-11:55

10:10-10:25

10:25-10:40

10:40-10:55

10:55-11:10

Scientific Session on DUID GOLDEN GATE A

Scientific Session on Clinical Toxicology GOLDEN GATE B

O1: Driving Under the Influence of JWH-018. Montgomery

O12: Determination of Gamma-Hydroxybutyric Acid in Dried Blood Spots with "On Spot" Derivatization and GC-MS: Method Development, Validation and Application. Ingels

O2: The prevalence of alcohol and drugs in seriously injured drivers in Belgium. Verstraete O3: Oral Fluid Cannabinoids: Windows of Detection, and Sensitivity, Specificity and Efficiency of the Draeger DrugTest¨ 5000 after Controlled Smoked Cannabis Administration. Huestis O4: DUID Case Involving "Legal High" Internet Drugs: Mephedrone, MDPV and Phenazepam. Spirk

11:10-11:25

O5: The Role of Legal Drugs in Serious Crashes. Drummer

11:25-11:40

O6: A Model Drugged Driving Law. Talpins

11:40-11:55

O7: Forensic Toxicological Investigations Concerning Motor Vehicle Drivers with a Suspended License: a Retrospective Five Year Review. Argo

O13: Aminorex Poisoning in Cocaine Abusers? Karch O14: Towards a model for residual hazards from chemically contaminated human remains. Noort O15: UPLC-MS/TOF: An easy and fast Screening Method for Clinical Toxicology. Henschel O16: The clinical utility of a comprehensive Time-of-Flight LC-MS serum drug of abuse panel in emergency intoxication cases. Gerona O17: Findings of MDMA and MDA in Hair, Blood and Urine by LC-ESI-MS/MS: Report of 11 Drug Facilitated Crime Cases with Anterograde Amnesia. Deveaux O18: A new degradation product of olanzapine. Saar

LUNCH IN YERBA BUENA EXHIBIT HALL WITH POSTERS P001-P100 11:55-13:40 (See Pages 10 - 14 for Scientific Poster Titles and Presenting Authors’ Names)

For more information and to register, visit: www.toxicology2011.org

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Wednesday, 28 September 2011 (cont.) 13:40-14:40

13:40-13:55

13:55-14:10

14:10-14:25

14:25-14:40

14:40-16:30

17:30-23:00

Scientific Session on DUID GOLDEN GATE A O8: Alcohol and Drugs among Randomly Selected Drivers. Augsburger O9: Isomers of Fluoroamphetamines (FAs) Detected in Forensic Cases in Denmark. Johansen O10: Free and Glucuronide Conjugate Plasma Cannabinoid Pharmacokinetics After Ad Libitum Smoking of a 6.8% Δ9-Tetrahydrocannabinol Cigarette. Karschner 011: Status Update for ForensicDB: A WebAccessible Spectral Database for Shared Utilization by Forensic Laboratories. Moore

Scientific Session on Postmortem Toxicology GOLDEN GATE B O19: A case report of death by respiratory depression following methadone ingestion in an eleven-monthold boy – Accident or Child abuse? Tournel O20: An Epidemic of Fatal and Non-fatal Paramethoxymethamphetamine (PMMA) Intoxications in Norway. Vevelstad O21: A Review of Deaths in Subjects Commencing A Methadone Maintenance Program – A 15 year follow up. Pricone O22: Hug Drug or Thug Drug? The Reincarnation of MDMA in San Francisco Postmortem Cases: Five Years in Review (2006-2010). Armenian SOFT BUSINESS MEETING GOLDEN GATE B

ESCAPE TO ALCATRAZ & SAN FRANCISCO BAY DINNER CRUISE

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Thursday, 29 September 2011 Scientific Session on Alternative Matrices GOLDEN GATE A

Scientific Session on Postmortem Toxicology GOLDEN GATE B

08:30-08:45

O23: Quantification of tetrahydrocannabinol in oral fluid collected with the Statsure, Quantisal or Certus device using UPLC-MS/MS. Wille

08:45-09:00

O24: Abuse of benzodiazepines and/or zolpidem proved by hair analysis. Lee

09:00-09:15

O25: Cannabinoids in oral fluid following passive exposure to marijuana smoke. Moore

09:15-09:30

O26: Rapid Method to Screen and Confirm Hair Ketamine and Metabolites in 1 Hour. Tsui

O43: Studies on the metabolism of three model drugs by fungi colonizing cadavers using LCMS/MS and GC-MS analysis. Ramírez O44: Demonstration of Postmortem Redistribution of 3,4-Methylenedioxymethamphetamine and 3,4Methylenedioxyamphetamine in A Case of Ecstasy Intoxication. Hearn O45: Influence of ante mortem perfusion on autopsy blood ethanol concentration. Kintz O46: Characterization of single nucleotide polymorphisms of cytochrome P450 in an Australian deceased population. Pilgrim

09:30-09:45

O27: Elimination Times for Drugs of Abuse in Oral Fluid from Patients with High and Repeated Intake - Case Examples. Øiestad

09:45-10:00

O28: LC-HRMS method for determination of levamisole in hair: application to clinical samples. Nalesso

10:00-10:15

O29: Oral Fluid Drug Testing of Chronic Pain Patients. Heltsley

10:15-10:30

O30: Oral Fluid and Plasma 3,4Methylenedioxymethamphetamine (MDMA) and Metabolite Correlation after Controlled Oral MDMA Administration. Desrosiers

08:30-10:30

10:30-11:00

O47: Opioids in Fatalities. Ojanperä O48: Alcohol is associated with the partitioning of Morphine between blood and vitreous humour compartments in deaths associated with the use of Heroin. Stephen O49: Benzodiazepine-like hypnotics in postmortem blood: Zopiclone- and zolpidem-related fatalities in Norway. Frost O50: Investigation of Markers to Indicate and Distinguish Death Due to Alcoholic Ketoacidosis, Diabetic Ketoacidosis and Hyperosmolar Hyperglycaemic State using Post-Mortem Samples. Paterson

BREAK Scientific Session on Clinical Research GOLDEN GATE A

Scientific Session on Alcohol Biomarkers GOLDEN GATE B

11:00-11:15

O31: Proteomic Profiles in Intrauterine Growth Restriction. Favretto

O51: Ethyl-glucuronide and ethyl-sulfate in placenta and fetal tissues by LC-MS/MS: biomarkers of transplacental ethanol transfer. Morini

11:15-11:30

O32: Concentrations of atomoxetine and its metabolites in oral fluid and matched plasma specimens. Pichini

O52: Detection of ethylglucuronide and ethylsulfate in dried blood spots. Hernandez Redondo

11:30-11:45

O33: Pharmakokinetics of tetrahydrocannabinolic acid A after intravenous administration. Wohlfarth

11:00-12:30

11:45-12:00

12:00-12:15

O34: In-vitro kinetics of the human cytochrome P450 isozyme catalyzed metabolism of the Aporphine n Alkaloid Glaucine Using LC-MS . Meyer O35: Urinary Excretion Kinetics of MDMA and its Phase II Metabolites Following Controlled MDMA Administration to Humans. Schwaninger

O53: Diagnostic Performance of Ethyl Glucuronide in Hair for the Investigation of Alcohol Drinking Behavior: A Comparison with Traditional Biomarkers. Sporkert O54: Predicting Blood Alcohol Concentrations after Social Drinking in Human Subjects where Absorption may be Incomplete. Coward O55: Comparison of different markers of chronic alcohol abuse in the assessment of driving fitness. Polettini

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Thursday, 29 September 2011 (cont.) 12:15-12:30

O36: Cannabinoids in Expectorated Oral Fluid from Daily Cannabis Smokers During Prolonged Monitored Abstinence. Milman

O56: Liquid chromatography-mass spectrometry measurement of the alcohol biomarker phosphatidylethanol (PEth) in blood. Helander

LUNCH IN YERBA BUENA EXHIBIT HALL WITH POSTERS P101-P200 12:30-14:00 (See Pages 15 - 19 for Poster Titles and Presenting Authors’ Names) 14:00-15:30 14:00-14:15

14:15-14:30

Scientific Session on Clinical & Preclinical Research GOLDEN GATE A O37: Pharmacokinetics of Single Dose Clonazepam in Whole Blood and Oral Fluid. Kronstrand O38: Extended Plasma Cannabinoid Excretion in Chronic Daily Cannabis Smokers During Sustained Abstinence. Bergamaschi

14:30-14:45

O39: Detection of Anabolic Steroid Testosterone in Equine Plasma and Urine after Controlled Administration to Horses. Negrusz

14:45-15:00

O40: The uPA+/+-SCID Chimeric mouse: a model for in vivo study of steroid metabolism. Leen

15:00-15:15

O41: In vitro metabolic studies using homogenised horse liver. Wong

15:15-15:30

O42: Acute Oral 3,4-Methylenedioxymethamphetamine (MDMA) Effects on Immediate, Short Term and Delayed Memory. Hartman

O57: Detection of plant alkaloids in fatalities: the advantage of general (non-targeted) screening. Elliott O58: One-year monitoring of nicotine use in sport: frontier between potential performance enhancement and addiction issues. Marclay O59: Nano Ultra-Performance Liquid Chromatography Time-of-Flight Mass Spectrometry Multi-analyte Screening of Regulated Drugs and (un)known Biotoxins. Nielen O60: The use of Hybrid Linear Ion Trap LC-MS and UHPLC QTOF-MS in the detection of glucuronide metabolites in urine. Taylor O61: Semi-Quantitative Analysis in General Unknown Screening by Liquid Chromatography Hybrid Quadrupole Time-of-Flight Mass Spectrometry (LC-QTOF-MS). Broecker O62: MALDI-Mass Spectrometric Imaging – Analysis of Cocaine and Metabolites in a Single Hair. Kraemer TIAFT BUSINESS MEETING GOLDEN GATE B

15:30-17:30

18:30-00:00

Scientific Session of Analytical Toxicology GOLDEN GATE B

UNITING NATIONS PRESIDENTIAL GALA DINNER

For more information and to register, visit: www.toxicology2011.org

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Friday, 30 September 2011 08:30-10:30

Scientific Session on Synthetic Cannabinoids GOLDEN GATE A

Scientific Session on Analytical Toxicology GOLDEN GATE B

08:30-08:45

O63: Identification of the Major Metabolites of 6 Synthetic Cannabinoids Present in "Herbal Mixtures" in Human Urine Samples Using LC-MS/MS Techniques. Hutter

08:45-09:00

O64: ‘Spice’ in oral fluid: LC-MS/MS identification of active compounds. Coulter

09:00-09:15

O65: Determination of a synthetic cannabinoid, JWH018 and its metabolites in rat urine and hair samples using UPLC-MS/MS. Kikura-Hanajiri

09:15-09:30

O66: Application of Liquid Chromatography-Tandem Mass Spectrometry for Identification and Quantification of 'Legal Highs' Active Components' in Blood. Tokarczyk

09:30-09:45

09:45-10:00

10:00-10:15

10:15-10:30

O67: Determination of ‘Spice’ Cannabinoids in Serum and Hair by Liquid Chromatography-Tandem Mass Spectrometry. Neukamm O68: Quantitative Analysis of Synthetic cannabinoids JWH018, JWH073 and JWH250 in Routine Oral Fluid Specimens. Rana O69: Case Report: Synthetic Cannabinoid JWH-175, MDEA and MDA Involved Death in San Francisco. Gordon O70: LC-ESI-MS/MS analysis of synthetic cannabinoids in serum: Experiences regarding the spectrum of compounds and long-term detectability from 900 forensic & clinical samples. Kneisel

10:30-11:00 11:00-12:30 11:00-11:15

11:15-11:30

11:30-11:45

11:45-12:00

O85: The First Documented Case With Positive 1(3-Trifluoromethylphenyl) Piperazine (TFMPP) Results at the Office of the Chief Medical Examiner, City and County of San Francisco, California. Karamanidis O86: Proof of Concept for a Comprehensive Method for Rapid Drug Screening of Whole Blood with UHPLC Accurate-mass TOF LC/MS. Guale O87: Universal LC-MS Library – Dream or Reality? Use of a new drug and metabolite library recorded on a LXQ linear ion trap for drug screening using QTrap instruments. Wissenbach O88: Identification of New Amphetamine-Related Designer Drugs in Drug Seizures by means of GCMS, GC-MS After Derivatization With 2,2,2Trichloroethyl Chloroformate, and U-HPLC/HROrbitrap-MS. Frison O89: Qualitative and quantitative analysis of 4methylmethcathinone (mephedrone) by DESI-MS. Stojanovska O90: Death by “Bath Salts”: Postmortem Tissue Distribution of MDPV Following Lethal Intoxication. Wyman O91: New trips on the block – A retrospective study in hair. Rust O92: Studies on the CYP Isoform-Dependent Metabolism of the Cathinone-derived Designer Drugs 3-Fluoromethcathinone and 3Bromomethcathinone Using LC-HRMS. Meyer

BREAK Scientific Session on Analytical Toxicology GOLDEN GATE A

Scientific Session on Analytical Toxicology GOLDEN GATE B

O71: Synthetic Cannabinoid Use: Experience with Urine Drug Testing. Kacinko O72: Development and validation of an LC-MS/MS method for the detection and quantification of designer drugs, amfetamines, benzodiazepines, opiates and opioids in urine using the turbulent flow technique. Schäfer O73: Prediction of Liquid Chromatographic Retention for Differentiating Structural Isomers. Tyrkkö O74: Combined Urine Drug Screening and Confirmation by Liquid Chromatography-Time-of-Flight Mass Spectrometry and Database Search Including Exact Mass Qualifier Ion(s). de Castro

O93: A Dual Approach to the Unequivocal Diagnosis of Botulinum Toxin Exposure. van der Schans O94: Specific and rapid detection of drugs from oral fluid using paper spray ionisation tandem mass spectrometry. Parkin O95: Street Drug Availability – The Impact on Toxicology Laboratories. Akrill O96: Fast and efficient quantification of 31 common drugs of abuse and benzodiazepines in whole blood using fully automated sample preparation and UPLC-MS/MS. Rasmussen

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Friday, 30 September 2011 (cont.) 12:00-12:15

12:15-12:30

O75: In Vitro Stability of Cannabinoids and Cannabinoid Glucuronides in Authentic Whole Blood and Plasma Specimens Following Controlled Smoked Cannabis. Schwope O76: Fast Targeted Screening of 234 Drugs and Poisons in Urine Using LC/MS/MS. Beyer

O97: 2-Nitro-MAM and 2-Nitro-Morphine: Potential Markers for Monitoring the Presence of Opiates in Urine Adulterated with Potassium Nitrite. Luong O98: Are Negative Screen Results Due to “Below Cut-Off” Levels Really Negative? Wong

LUNCH IN GOLDEN GATE FOYER WITH POSTERS P201-P300 12:30-14:00 (See Pages 20 - 24 for Poster Titles and Presenting Authors’ Names) 14:00-15:30

14:00-14:15

14:15-14:30

14:30-14:45

14:45-15:00

15:00-15:15

15:15-15:30

Scientific Session on Alternative Matrices GOLDEN GATE A O77: Developing exhaled breath as a matrix for the detection of Cannabinoids. Beck O78: Unusual Codeine-to-Morphine Ratio in a Hair Sample: Indicator for CYP2D6 Polymorphism? Baumgartner O79: Investigating Prehistoric Hallucinogen Consumption: An Archaeological Case Study from Lipez, Bolivia. Miller O80: Segmental hair analysis as a useful tool in assessment of prenatal exposure to diazepam. Senczuk-Przbylowska O81: Simultaneous quantification of various drugs of abuse in oral fluid collected with the Statsure, Quantisal or Certus device using UPLC-MS/MS. di Fazio O82: Concentrations of Cocaine and Cocaine Metabolites in Oral Fluid After Drinking Coca Tea. Reichardt

15:30-15:45

O83: Operation Paris: The Shannon Matthews Case. Chatterton

15:45-16:00

O84: Δ -Tetrahydrocannabinol (THC), 11-nor-9carboxy-THC (THCCOOH), cannabidiol (CBD) and cannabinol (CBN) in oral fluid following controlled, smoked cannabis Lee

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Scientific Session on Postmortem Toxicology GOLDEN GATE B O99: Postmortem peripheral blood fentanyl concentrations in 20 cases: analysis and comparison to prior studies. Lung O100: A Family Tragedy after Three Doses of Tylenol. Martz O101: 1,5-Anhydroglucitol and Methylglyoxal – New Post Mortem Marker for Glucose Metabolism Disorders? Hess O102: Use and abuse of amphetamine in Sweden subject demographics, concentrations in blood in the living and the dead and the spectrum of other drugs used. Jones O103: A Study on the Forensic Toxicokinetics of Popular Poisons in China. Yun O104: Postmortem Drug Screening by Non-Targeted and Targeted UPLC Mass Spectrometry Technology. Rosano O105: Fatal methanol poisonings in Finland 2004 – 2010 with attention to formic acid concentrations. Viinamäki O106: Distribution of Cannabinoids in Postmortem Specimens Ingle

16:00-16:30

BREAK

16:30-18:00

PRESENTATION OF AWARDS & CLOSING CEREMONY GOLDEN GATE B

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Scientific Posters Wednesday, 28 September 2011 11:55-13:40 hrs   P001 P002 P003 P004 P005 P006

Presenting Author

Analytical Toxicology Analysis of Gamma-hydroxybutyric acid (GHB) in Urine Samples using Liquid Chromatography with Tandem Mass Spectrometry (LC-MS/MS) Simultaneous analysis of cardiac glycosides in blood and urine by thermoresponsive LC-MSMS Confirmation of Propoxyphene and Norpropoxyphene in urine by Laser Diode Thermal Desorption (LDTD) Confirmation of Methadone and EDDP in Urine by Laser Diode Thermal Desorption (LDTD)Mass Spectrometry Direct and automated analysis of dried blood spots coupled with liquid chromatography-mass spectrometry Rapid Isolation of Tetrahydrocannabinolic Acid A From Cannabis Sativa Using Flash Chromatography

Elian Kanno Tremblay Tremblay Déglon Wohlfarth

P007

Analysis of Amphetamines and Cannabis by Head-Space APCI/ITMS

Yamada

P008

Synthesis of an isotopically labelled internal standard for THCA-A by reaction of Δ9-THC-D3 with magnesium methyl carbonate (MMC)

Roth

P009

Identification of xenobiotics in human plasma/serum using automated sample preparation, standardized high-performance-liquid chromatography, high resolution mass spectrometry and platform-independent libraries

Grobosch

P010

Proof of concept for a rapid and simple method for the analysis of amphetamines and psychotropic drugs in urine using high temperature vaporization and diffusion solid phase microextraction technique

Fujii

P011

Determination of Cocaine and Cocaine Metabolites in Single Hairs by the MALDI LTQ Orbitrap XL Instrument – Preliminary Results

Musshoff

P012

Development of an ELISA for detection of tapentadol in oral fluid and blood

Rodrigues

P013

A novel ELISA screen for detection of Sufentanil in human body fluids

Rodrigues

P014

Development of an ELISA for detection of Diphenhydramine in urine and blood

Rodrigues

P015 P016 P017 P018 P019 P020 P021

High Sensitive Detection and Analysis of Abused Codacet® (Acetaminophen-Codeine) by Surface-Ionization Methods Feasibility of Surface-Ionization Methods for Detecting Trace Amounts of Antidiabetic Preparations Development and validation of an LC-MS/MS method for the detection and quantification of designer drugs, amfetamines, cocaine, opiates and opioids in blood and serum Development and Validation of a Novel Homogeneous Immunoassay for the Detection of Tapentadol in Urine Mix-mode TiO-C18 Monolith Spin Column Extraction and GC-MS Analysis for the Simultaneous Assay of Organophosphorus Compounds, Glufosinate and Glyphosate in Human Serum and Urine. A Validated Method for Simultaneous Screening and Quantification of 31 Drugs of Abuse in Whole Blood by Fully Automated SPE and UPLC-QTOF/MS Simultaneous determination of dimethyltryptamine and β-carbolines in plasma samples by LCMS/MS

Khasanov Khasanov Ewald Wang Saito Dalsgaard Oliveira

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P022

Production of identical retention time and mass spectrum for D -tetrahydrocannabinol and cannabidiol following derivatisation with trifluoroacetic anhydride

Paterson

P023

Identification of betaine ester I octyl chloroacetate by thin layer chromatography

Mohamed

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Scientific Posters Wednesday, 28 September 2011 11:55-13:40 hrs P024

Validated LC/MS Methods for the Determination of Amanita phalloides Toxins in Human Urine

Merová

P025

Detection and Analysis of 30 Compounds in Oral Fluid via Ultra High Pressure LC-MS-MS without Solid Phase Extraction

Workman

P026

Certification of Reference Materials: Purity Analysis of Morphine-3β-D-Glucuronide by Quantitative NMR, Enzymatic Hydrolysis LC-MS/MS Assay, and Mass Balance Purity Factor

Jian

P027

A Combined Method for the Analysis of Barbiturates and 11-nor-9-carboxy-Δ -THC in Urine by LC/MS/MS

Workman

P028

Development of an Advanced Toxicology Method Utilizing Turbulent Flow Technology

Pentis

P029

Enterprise LIMS Data Exchange in Clinical, Toxicology, and Public Health Laboratories

Ward

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P030 P031

Urine Barbiturate Analysis Using an Improved SPE Protocol and LC/MS/MS; Achieving Chromatographic Resolution of Isobaric Amobarbital & Pentobarbital The Application of HILIC Stationary Phase in Analysis of Anticonvulsants in Whole Blood by Means of NPLC-MS/MS. ®

Rummel Lechowicz

P032

Quantitative Analysis of Carboxy-THC in Urine Using UPLC -MS/MS

Lee

P033

Analysis of Amphetamines and Ephedrines in Urine using Solid Phase Extraction and Direct Mass Spectrometry

Inoue

P034

Benefit from the use of Deconvolution Reporting Software (DRS) and the Forensic Toxicology DataBase Library combined with Retention Time Locking (FT-DBL-RTL) in toxicological screening with GCMS in a forensic laboratory.

Brede

P035 P036 P037 P038 P039 P040

Evaluation of Solid-Phase Extraction Cartridges for the Quantification of THC-COOH in urine using Gas Chromatography-Mass Spectrometry. Simple Urine Screening for the Determination of Selected Benzodiazepines by Direct Injection LC/ESI-MS Method Optimization for the GCMS Determination of Amphetamines and Amphetamine-like Derivates in Urine Using On-line Trifluoroacetylation Analysis of drugs of abuse by GC-MS in dried blood spot sample matrix Protein Adduct Based Biomarkers of Chemical Warfare Agents: Characterization of HN-2 and HN-3 Adduction of Model Peptides High Mass Accuracy LC-MSMS Instrumentation with Improved Identification Software to Screen Compounds of Forensic Interest

Leong Athanaselis Fábián Lillsunde Thompson Philippe

P041

Proof of Concept for Drug Screening Using a High Resolution Accurate Mass System

Wang

P042

Direct Screening of “Herbal Blends” for Synthetic Cannabinoids by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass (MALDI-TOF) Spectrometry

Gottardo

P043

A Rapid Sample Preparation Procedure Utilizing Hybrid Quadrupole Linear Ion Trap Mass Spectrometry Detection as an Analytical strategy for Controlled Drugs in Blood and Application to Forensic Cases in Ireland

Dowling

P044

Evaluation of Supported Liquid Extraction (SLE) for the Determination of Cannabis and Synthetic Cannabinoid Compounds in Blood.

Dowling

P045

Analytical Reference Standards: Synthesis and Characterization of ±-threo-Ritalinic Acid-D10 Hydrochloride

Marek

P046

Method Development for Enantiomer Separation of Minor Metabolites from GammaHydroxybutyrate using Liquid Chromatography Mass Spectrometry

Kaplan

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Scientific Posters Wednesday, 28 September 2011 11:55-13:40 hrs P047

Proof of Concept for Analysis of 120+ Drugs in Whole Blood using LC/MS/MS

Newland

P048

Pyrolysis of Fentanyl: Isolating Markers of Smoking Abuse

Nishikawa

P049 P050 P051 P052 P053

Simultaneous Solid Phase Extraction and GC/MS Quantitation of Cocaine, Cocaine Metabolites, Standard and Extended Opiates, and Opiate Metabolites from Whole Blood. A Simplified Approach to the Extraction of Amphetamines from Urine using Supported Liquid Extraction prior to UPLC-MS/MS Analysis. A Novel Approach to the Simultaneous Extraction of 11-nor-9-carboxy-Δ9-THC (THCCOOH) and THCCOOH-Glucuronide from Urine using Supported Liquid Extraction prior to UPLCMS/MS Analysis. Extraction of Opioids from Urine using Supported Liquid Extraction prior to UPLC-MS/MS Analysis Reduction of Lorazepam to Delorazepam during Treatment of Urine Specimens with βGlucuronidase Enzyme

P054

Liquid handling of whole blood in a fully automated sample preparation setup

P055

WITHDRAWN

P056

New Tools for the Analysis of Cannabinoids in Blood

P057 P058

Development of an Analytical Method for the Simultaneous Detection of Abused Drugs, Their Metabolites and Common Adulterants in Blood by Precipitation and UPLC/MS/MS Development of Rapid LC/MS/MS-based Methods for Confirmatory Analysis of Opiates and Benzodiazepines

Jellick Jones Williams Jones Fu Wederkinck Andersen

Baumann Silva-Torres Stoll

P059

Construction of a LC-MS/MS Library for Screening 242 Drugs and Toxic Compounds

Zhang

P060

Identification and Quantification of 28 Drugs and Toxic Compounds in Blood, Urine and Gastric Content using LC-MS/MS

Liang

P061

Inhibition of 1, 4-butanediol metabolism in human liver in vitro

Presenting Author Bender

P062

Sublingual Buprenorphine Pharmacokinetics: Gender differences

Moody

P063

Distribution of Nalbuphine in Putrid Albino Rat Organs by HPLC-UV

Soliman

Clinical & Preclinical Research

+/+

P064

The uPA -SCID Chimeric Mouse: a Model for in vivo Study of Mibolerone Metabolism

Lootens

P065

Acute Administration of MDMA Induces Hepatocellular Damage, Oxidative Stress and Lipoperoxidation in Rat Liver

Karch

P066

Evaluation of In Vitro Metabolic Assay Systems for Common Drugs of Abuse

Schneider

P067

Effects of Ethanol on the Toxicokinetics of Methamphetamine in Rabbits

Wang

P068

Pharmacokinetic Drug-drug Interactions of MDMA with Methamphetamine in Brain

Fuchigami

P069

Effect of Co-Administration of MDMA and Methamphetamine on Dopamine and serotonin levels in rat brain

Ikeda

For more information and to register, visit: www.toxicology2011.org

12


Scientific Posters Wednesday, 28 September 2011 11:55-13:40 hrs Synthetic Cannabinoids

Presenting Author

P070

Development of New Polyclonal Antibodies for the Screening of JWH Synthetic Cannabinoids and Metabolites.

Benchikh

P071

JWH 250 Metabolite Identification and Reactive Metabolite Evaluation

Liu

P072 P073 P074 P075 P076

Identification of newly distributed designer drugs, synthetic cannabinoids and cathinone derivatives in Japan Screening for K2/Spice: Monitoring JWH-018, 073, 081 and 250 and some prominent metabolites by HPLC-MS/MS Capabilities of Ultra-High-Pressure Liquid Chromatography – High Resolution/High Accuracy Orbitrap Mass Spectrometry (UHPLC-HRMS) in Structural Characterization of New Amphetamine-Related and Cannabinomimetic Designer Drugs An Effective and Rapid Sample Preparation Using DPX-Polar Tips for the Detection of Synthetic Cannabinoids in Urine by LC/MS/MS Method Development for the Identification and Determination of Synthetic Cannabinoid Metabolites in Hydrolyzed Urine by LC/MS/MS

Uchiyama Dawson Frison Dalvi Rigdon

P077

Analysis of Synthetic Cannabinoids in Herbal Blends by GC Tandem Mass Spectrometry

Macherone

P078

Synthetic Cannabinoid Screening Assay in Urine Specimens by LC/MS/MS

Toivola

P079 P080 P081

Dose Dependent Disposition of the CB1 Agonist JWH-018 in the Mouse following Inhalation of the Herbal Incense “Buzz” Identification of the Synthetic Cannabimimetic 3-(1-adamantoyl)-1-pentylindole: Another Chapter in the Cat-and-Mouse Game Severe intoxications after consumption of products containing synthetic cannabinoids – analytical findings versus clinical symptoms

Amira Kneisel Kneisel

P082

Bioanalytical Quantification of MDPV; a Paranoia Inducing Designer Stimulant

Presenting Author Alexy

P083

Multi-Target Screening for New Designer Drugs by LC-MS/MS

Ambach

P084

Ion Trap GC-MS/MS analysis of “Bath Salts” in biological samples

Honnold

P085

Development of a novel Benzylpiperazine ELISA assay for urine and blood

Rodrigues

P086

Improved GCMS Derivatization Techniques for Analysis of New Designer Drugs: Methylone, Ethylone, Butylone, Mephedrone, and Methedrone

Carrell

P087

Identification and Differentiation of Methcathinone Analogues by GC-MS

Tsujikawa

P088

Bizarre behavior and death following ingestion of MDPV (“Bath Salts”)

Clay

P089

Determination of Cathinone Derivatives and Other Designer Drugs in Serum by Comprehensive LC-Triple Quadrupole MS/MS Analysis

Swortwood

P090

Stability of Cathinones in Whole Blood Samples

Sørensen

Bath Salts

P091 P092

A Newly Found Mephedrone Analogue – 4-Methylethcathinone Legally Dealt on the Czech and Slovak Drugs of Abuse Market Simultaneous Determination of Mephedrone, Methylone, MDPV, and Amphetamines in Urine by LC/MS/MS

Vorisek Rigdon

P093

Early Detection of Methcathinone and Related Compounds in Blood and Urine

Fürmanova

P094

2-Diphenylmethylpyrrolidine (Desoxy D2PM): another pipradrol analogue

Puchnarewicz

13


Scientific Posters Wednesday, 28 September 2011 11:55-13:40 hrs P095

A Validated Quantitative Method for Analysis of MDPV and Mephedrone (Bath Salts) in Urine Using LC-MS/MS

Lu

P096

Concept for Methods for the Prompt Identification of New Psychoactive Substances

Rofe

P097

Fluoro-and Methyl-Ephedrine Metabolites in Routine Urine Testing for Designer Stimulants

Uralets

P098 P099 P100

Analysis for Mephedrone (4-Methylcathinone) in Rat Plasma and Rat Brain Homogenates by Liquid Chromatography-Mass Spectrometry Routine Screening of Human Urine for 14 New Designer Stimulants Found in “Bath Salts” Using GC/MS Identification of Cannabis Using Gas Chromatography – Mass Spectrometry

Andrenyak Rana Lamchin

For more information and to register, visit: www.toxicology2011.org

14


Scientific Posters Thursday, 29 September 2011 12:30-14:00 hrs Postmortem Toxicology

Presenting Author

P101

Determination of blood cyanide in several poisoning cases

Minakata

P102

Histopathological evaluation of organs in cases of fatal pesticide poisoning

Kanchan

P103

Toxicokinetics and Detection of ACTP-Ester Residues in Goat Using HPLC

Sahu

P104

Homicidal Aluminium Phosphide Poisoning - A Case Report

Chandrakant

P105

Fatal poisoning with Taxus baccata: Quantification of paclitaxel, 10-deacetyltaxol, baccatin III, 10-deacetylbaccatin III and cephalomannine (taxol B) and of 3,5-dimethoxyphenol in post mortem body fluids by LC-MS/MS.

Grobosch

P106

Microanalysis of Carbon Monoxide in Decomposed Blood and Hepatic Tissue by Headspace Gas Chromatography and Mass Spectrometry

Hao

P107

Concentration Distributions of d,l-Methadone in Peripheral Blood from Forensic Autopsies, DUID Suspects and Users of Illicit Drugs

Holmgren

P108

Internet – Assisted Suicide (with pharmaceuticals)

Rohde

P109

Detection of Pentobarbital in Teeth Recovered from Skeletonized Remains by Microwave Assisted Extraction and Gas Chromatography-Mass Spectrometry

Betit

P110

A fatal case of simultaneous ingestion of mirtazapine, escitalopram and valproic acid

Gerace

P111

Association Between Antipsychotic Drugs and Sudden Cardiac Death

Aknouche

P112

Evaluation of the i-STATÂŽ1 handheld analyzer for postmortem vitreous humor chemistry analysis

Oles

P113

Screening and Confirmation of 29 Benzodiazepines and Hypnotics in Urine by LC-MS/MS

Liu

P114

Acute Toxicity by Hair Dye in Upper Egypt

Ahmed

P115

Fatal poisoning with Aconitum napellus, lethal thyroid storm or both?

Keller

P116

Hydrogen Sulphide and Cocaine: A Lethal Cocktail

Button

P117

Postmortem Toxicological Investigation of Alcoholic Ketoacidosis

Bosman

P118

Suicide by Asphyxiation due to Helium and Argon

Musshoff

P119

Preliminary Analysis of Distribution of Sulfonylureas in Tissues of Poisoned Animals

Ibragimova

P120

Postmortem Drug Concentration Ranges in Blood for the Non-Intoxicated State Compared to Commonly Cited Therapeutic Ranges in Serum

Linnet

P121

The Role of Methadone in Drug Related Deaths: the Italian Experience 2000-2010

De Giovanni

P122

Pilot Study: In Vitro Metabolic Effects of Escherichia coli on Cocaine and Fentanyl

Martindale

15


Scientific Posters Thursday, 29 September 2011 12:30-14:00 hrs P123

Analysis of cyanide in biological specimens: a comparison between a color test and a validated headspace gas chromatography method and its application in a fatal intoxication case.

Souza Pelição

P124

Liquid Chromatography/Time-of-Flight Mass Spectrometry Analysis on Post-mortem Blood Samples for Targeted Toxicological Screening

Josefsson

P125

Use and limitation of models for microbial ethanol production in post-mortem cases

Boumba

P126

Fatal mephedrone intoxication – a case report

Tokarczyk

P127

Investigations of codeine-related deaths should include concentrations of morphine and the morphine metabolites M3G and M6G

Frost

P128

Buprenorphine Related Deaths. Interpretation of post-mortem blood and urine levels

Seldén

P129

Suicide With bk-MBDB (Butylone): Clinical and Toxicological Findings

Klys

P130

The distribution of Doxepin and Sulpiride in a human poisoning death

Wei

P131

A Complex Case of Murder Involving Zolpidem

Pinorini-Godly

P132

6-Acetylmorphine of Unknown Origin in a Case of Morphine Overdose

Herndon

P133 P134

Relationship Between Femoral Blood and Liver Fentanyl Concentrations in Cause of Death Determination Fatal Consequences of Datura Poisoning in a Case of Robbery: Clinical, Toxicological and Forensic Features

Kloss Tournel

P135

Determination of barbiturates in postmortem whole blood sample using hollow fiber liquidphase microextraction and GC/MS

Menck de Almeida

P136

The Relationship Between Ante- and Post-Mortem Amlodipine Concentrations in Whole Blood Versus Plasma

Button

P137

Fatal Methanol Intoxication - Two Exceptional Case Reports

Dally

P138

Development of drug identification and semi quantitative analytical program by gas chromatography-mass spectrometry based on drug patterns in autopsy cases of Korea

Kim

P139

Rapid Analysis of Liver, Muscle and Vitreous Humor Samples using the Randox Whole Blood Drugs of Abuse (DOA) Arrays for use as a Near-Body Screen During Autopsy.

McLaughlin

P140

Toxicological Screening of Human Hair after Exhumation: The Potential Interest of Insect Pupae

Humbert

P141

Barbitone (barbital) and death in the workplace

Puchnarewicz

P142

Poisoning Deaths in the Region of Epirus, North-Western Greece During the Period 19982010

Boumba

P143

Diving under the influence of drugs

Villain

P144

Determination of Δ -Tetrahydrocannabinol and 11-nor-Δ -Tetrahydrocannabinol-9-carboxylic acid Bile Concentrations and their Importance in the Investigation of Forensic Cases

Athanaselis

P145

Postmortem Hair Analysis Verifies Heroin Exposure and Leads to a Killer

Athanaselis

P146

Interpretation of High Blood Clozapine Concentrations - A Case Report

Athanaselis

P147

Methadone-Related Deaths: A Worrying Increase

Vignali

9

9

16


Scientific Posters Thursday, 29 September 2011 12:30-14:00 hrs P148

Fatal Intoxication Due to Dichloromethane Exposure: a Case Report

Stramesi

P149

Unnatural Death Profiling in Cyprus: A Ten Year Study (2000-2010)

Liveri

P150

Influence of CYP2D6 and ABCB1 Gene Polymorphisms on the Disposition of the Enantiomers of Venlafaxine and O-desmethylvenlafaxine in Postmortem Femoral Blood

Karlsson

P151

Application of Enantioselective Analysis Combined with Genotyping: Implications for Interpretation of Postmortem Citalopram Levels

Kugelberg

P152

The use of pharmacogenetic analysis in forensic toxicology - Relation between CYP2D6 genotype and ethylmorphine/morphine ratios in post mortem blood

Zackrisson

P153

Vitreous Humor as an Alternative Matrix in Forensic Toxicology

Brunet

®

P154

Evaluation and Comparison of Neogen Corporation’s Methadone / LAAM ELISA Kit with Postmortem Specimens

Simons

P155

Distribution of the Inhalant 1, 1-Difluoroethane (HFC-152a) in the Rat

Ochi

P156

Cocaine, Metabolites and Derivatives in Vitreous Humor Using Disposable Pipette Extraction Tips and Gas Chromatography-Mass Spectrometry

Peres

P157

Alcohol in Fatal Traffic Accidents in Espírito Santo, Brazil

Barreto Mendonça

P158

Enzyme-Linked Immunosorbent Assay (ELISA) Analytical Performance Validation for the Detection of 20 Drug Categories in Human Performance and Post-mortem Blood

Baker

P159

Enzyme-Linked Immunosorbent Assay (ELISA) Casework Performance Validation for the Detection of 20 Drug Categories in Blood

Razatos

P160

Enzyme-Linked Immunosorbent Assay (ELISA) Validation for Positive Cutoff Concentrations of 20 Drug Categories in Human Performance and Postmortem Blood Samples

Hwang

P161

Contribution of Alcohol and Drugs to Fatal All-Terrain Vehicle Accidents in West Virginia

Bailey

P162

Simultaneous Determination and Quantification of Nine Opioids in Blood, Plasma, and Tissue Homogenates Using Methoxyamine/MSTFA Dual Derivatization and Mini-Bore Fast GC/MS-EI SIM

Baker

P163

Strychnine - a fatal case in the UK

Puchnarewicz

P164

Fatal Drug Intoxications Involving Oxymorphone

Gebhardt

P165 P166 P167

Heroin overdose and myocardial damages: the relationship between toxicology and immunohistochemistry investigations in 95 cases The analysis of gastric contents to discriminate between oral and intravenous administration of methamphetamine. Comparison of Ketamine and Norketamine Levels in Bone Marrow following Acute and Chronic Ketamine Exposure

Busardò Busardò Betit

P168

Case Report: Clinical and Postmortem Findings in a Fatal Valproic Acid Poisoning

Lanaro

P169

Blood alcohol levels in suicide by hanging cases in the State of Sao Paulo, Brazil

Leyton

17


P170

Clozapine Overdose in an Embalmed Case

Ng

P171

Stimulant Drugs in Oral Fluid in the UK

Akrill

P172

Methadone Incidence in Medical Examiner’s Cases in the City and County of San Francisco

Easterling

Workplace Drug Testing

Presenting Author

P173

Controlled Substances and Quotas. The impact of scheduling actions on Controlled Substances and the List I chemicals ephedrine, pseudoephedrine and phenylpropanolamine

Dang

P174

Detection of drugs of abuse in urine – do standard test panels cover the actual substances?

Dyrkorn

P175

Simple and Highly Efficient Drugs of Abuse Testing Methods by SPE and LC/MS/MS

Dioumaeva

P176

GC-TOFMS Analysis with Auto-Derivatization for Forensic Urine Drug Screening by SAMHSA Guidelines

Heim

P177

Cannabis and cocaine detection in workplace drug testing in Italy

Santoro

P178

Analysis of 2008-2009 Urine Drug Testing Results from a Medical Review Officer Data Source

Baylor

P179

Analysis of Selected Drugs of Abuse and their Pyrolytic Products by LC/MS/MS

Oldfield

P180

Swiss Guidelines 2011 for Drugs of Abuse Testing

Binz

P181

UPLC -MS/MS Method for SAMHSA Compliant Workplace Urine Drug Testing

Lee

P182

Anomalous Results of Morphine and 6-acetylmorphine in Urine Samples

Lewallen

P183

Workplace Drug Testing: Outcomes after One Year of Observation

Santoro

P184 P185 P186

®

Evaluation of the Randox Biochip Array Technology for the screening of drugs of abuse in urine A Simplified Approach to the Extraction of Benzodiazepines from Urine using Supported Liquid Extraction (SLE) prior to LC-MS/MS Analysis. Interpretation of Lateral Flow Immunoassay Drug Test Results: Evaluation of the Drug Panel Reader

Polettini Williams Gunnar

P187

Detection of Synthetic Urine in Workplace Drug Testing Specimens

Linden

P188

Specimen Validity Testing (SVT)- Analyzing pH, Creatinine Concentration and Specific Gravity in Korea

Ko

P189

WITHDRAWN

P190

Potency of Illicit Cannabis in Japan

Takagi

For more information and to register, visit: www.toxicology2011.org

18


Scientific Posters Thursday, 29 September 2011 12:30-14:00 hrs

Solid Doses

Presenting Author

P191

Comprehensive Two-Dimensional Gas Chromatography Time-of-Flight Mass Spectrometry (GC´GC-TOFMS) for Profiling of Illicit Drug Samples

Schäffer

P192

Prevalence and co-occurrence of active ingredients of ‘legal highs’

Byrska

P193 P194

Advanced LC-MS Approaches for the Detection of Synthetic Cannabinoids in Unknown Samples Quantitation of Esterified and Non-Esterified Steroids in Oil-Based Injectables with SPEUHPLC-DAD

Grabenauer Härtel

P195

Composition Analysis of “Legal Highs” by GC-EI-MS for Medico-Legal Purposes

Rojek

P196

Enantioseparation of Methylamphetamine by Capillary Electrophoresis: a Survey of the Synthetic Route of Methylamphetamine Samples Seized in the Australian Capital Territory (ACT)

Kelly

P197

A fast and inexpensive procedure for the isolation of synthetic cannabinoids from ‘Spice’ products using a flash chromatography system

Moosmann

P198

The Identification of Vapours from Illicit Cocaine Samples Using Static Head-Space Gas Chromatography Mass Spectrometry (HS-GC-MS)

Rofe

Clinical Toxicology

Presenting Author

P199

RP-HPLC Determination of Benzhexol Hydrochloride in Tablet Formulations and Urine

Ahmed

P200

Acute Deliberate Organophosphate (Coumaphos) Poisoning with Intermediate Syndrome in a One Year Old Child

Kiat

For more information and to register, visit: www.toxicology2011.org

19


Scientific Posters Friday, 30 September 2011 12:30-14:00 hrs

Clinical Toxicology

Presenting Author

P201

Reporting Two Suicidal Fatalities Due to the Ingestion of Chlorfenvinphos Formulations: Simultaneous Determination in Tissues of the Pesticide and the Petroleum Distillates by GCFID/GC-MS

Martínez

P202

Antidepressants in urine using the Triage® TOX Drug Screen fluorescent immunoassay followed by confirmation via direct injection LC-MS/MS

Banaszczyk

P203

Target screening of drugs from Dried Blood Spot samples based on LC-MS/MS and on-line desorption

Lauer

P204

Application of ultra high pressure liquid chromatography tandem mass spectrometry to the analysis of antiarrhythmic drugs in serum and plasma.

Thomas

P205

HIV/aids risk questionnaire accuracy to detect drug use in prison

Carvalho

P206

Validated method for the determination of Misoprostol Acid in whole blood by Ultra Performance Liquid Chromatography – Tandem Mass Spectrometry

Simões

P207

Validated method for quantitation of psilocin in plasma by LC-MS/MS and study of stability

Martin

P208

Thiethylperazine Intoxication in a Pregnant Woman in her 12th Week of Pregnancy

Ondrová

P209

Comparison of opioid analysis in whole blood and dried blood spots

Jantos

P210

Concentration Patterns of Buprenorphine and Metabolites, with and without Naloxone, in Human Urine

Carlisle

P211

Toxicological and Clinical Evaluation of Probationers for Marijuana Use in İzmir, Turkey

Akgür

P212

Development of a Colorimetric Assay Kit for the Measurement of Acetaminophen with Enhanced Precision and Assay Range on the Fully Automated RX Series Analysers

Bell

P213

Acute Poisoning by Slimming Capsules “Best Life”: Clinical and Analytical Data

Jamey

P214

Analysis of Oral Anti-diabetic Drugs and their Metabolites in Blood and Urine by Thin-Layer Chromatography

Ibragimova

P215

Analysis of Markers for Nicotine Exposure in Urine Specimens

Haglock

P216

In vivo Levamisole metabolism in humans

Bertol

P217

Toxicokinetics of Isopropanol, Acetone, Methylethylketone and Toluene Following an Overdose

Eysseric

P218

Fatal and non fatal methadone related intoxications in the region of Thessaloniki (Northern Greece)

Raikos

P219

Determination of Clenbuterol in Human Plasma and Urine by Liquid Chromatography Tandem Mass Spectrometry: Diagnosis of an Overdose in a Bodybuilder

Costa

P220

Persistent biomarkers for verification of exposure to organophosphate and organophosphothioate pesticides – a case study

van der Schans

P221

Case report of a Clozapine Intoxication of a 13-Month-Old Girl: Quantification of Clozapine and Its Main Metabolites in Serum and Urine Samples Over 11 Days

Wohlfarth

P222

Development of Two Monoclonal Antibodies for the Broad Detection of Barbiturates and for the Detection of Meperidine and the Metabolite Normeperidine

Benchikh

20


Scientific Posters Friday, 30 September 2011 12:30-14:00 hrs

P223

Application of Matrix Dedicated Evidence Biochip Array Kits to the Simultaneous Determination of Tricyclic Antidepressants (TCAs), Buprenorphine, Methylenedioxymethamphetamine (MDMA) and Other Drugs of Abuse in Urine and Blood

Piper

P224

Development of a Highly Sensitive Polyclonal Antibody for Measuring Lidocaine in Biological Samples

Lowry

P225

Use of anabolic-androgenic steroids in connection with violent crimes

Lood

P226

Observations on Methadone Co-Prescriptions and Non-Prescription Medications in a Pain Patient Population

West

P227

Characterization of Genetic Variants of Human Serum Transferrin

Santoro

P228

Validated analytical method for the determination of meta-chlorophenylpiperazine (m-CPP) in human plasma and urine by liquid chromatography-tandem mass spectrometry (LC-MS/MS)

Polesel

P229

The Relationship between Agouti-Related Protein (AgRP) and Leptin in Cannabis Smokers

Fathy

P230

Identification of Human Hepatic UDP-glucuronosyltransferases (UGTs) Involved in Metabolism of Ethanol

AlSaabi

P231

Production of Recombinant Hydroxyacid-oxoacid Transhydrogenase and its Application to Measure Gamma Hydroxybutyrate by a Colorimetric Assay

Alzeer

P232

Sensitive Determination of Amatoxins Using UPLC-MS-MS

Ishii

P233

Forensic Aspects of Teargas Toxicity

Bendary

P234

Cross-Reactivity of Tapentadol Specimens with DRI Methadone Enzyme Immunoassay

Collins

P235

Poisoning profiles in a rural agrarian society

Gambhir

P236

Quantitative U-HPLC-MS Analysis of 14 Benzodiazepines in Urine Using a High Resolution Accurate Mass Exactive Mass Spectrometer Equipped with a Higher Energy Collisional Dissociation Cell

He

P237

New Tools for the Analysis of Cannabinoids in Blood

Baumann

P238

Imidazole Cyclodextrin (ImCD) as an Antidote for Cyanide Poisoning: In Vitro and In Vivo Results

Yamagiwa

P239

Methadone and Metabolites in Hair of Methadone-Maintained Pregnant Women and Their Infants

Himes

For more information and to register, visit: www.toxicology2011.org

21


Scientific Posters Friday, 30 September 2011 12:30-14:00 hrs P240

Alternative Matrices Validation of a solid phase extraction procedure for identification and quantification of cocaine, metabolites and derivatives in meconium using GCMS

Presenting Author Alves

P241

Mistreatment of Older People in a Retirement Home: Evidence of Chemical Abuse through Hair Analysis

DumestreToulet

P242

Case Report of THC Identified in Pubic Hair Documenting Drug Use by a Public Authority Official

Aknouche

P243

Comparison Study of Oratect Oral Fluid Drug Screen Devices for Amphetamine, Cocaine, Opiates, Methamphetamine, THC and PCP with LC/MS/MS Confirmation

Wang

P244

Evaluation of On-Site Oral Fluid Drug Screening Devices

Bott

P245

Percentages of N- and O-demethyl metabolites of tramadol in hair – Use for assessment of tramadol intake vs. external contamination

Madry

P246

Effect of reducing the cut-off concentration for opioids in oral fluid screening

Garnier

P247

Quality Control in Hair Analysis: The Society of Hair Testing Experience

Jurado

P248

GC-MS analysis of hair for the detection of drugs of abuse and their metabolites

Raikos

P249

Validation of a Simplified GC-MS Procedure for Confirmation of Oral Fluid On-Site Immunoassay Tests in a Program of Roadside Toxicological Screening of Drivers

Pascali

P250

Evaluation of Different Hair Color and Ethnicity Types Following Surface Contamination with Cocaine and Laboratory Decontamination

Bynum

P251

Simultaneous application of the Cozart® DDS801 and DrugWipe® 5 oral fluid screening devices in an experimental procedure for roadside drug testing

Salomone

P252

Performance of Four Oral Fluid On-site Devices for Monitoring Drugged Driving Confirmed by UHPLC-MS/MS Analysis

Strano-Rossi

P253

Confirmation of Cannabinoids in Oral Fluid without Sample Pre-Treatment: UHPLC-MS/MS and SPME-GC/MS

Strano-Rossi

P254

Evidence of cathinone use through hair analysis using LC-MS/MS

Cirimele

P255

Concentration of Tramadol in Human Hair

Cirimele

P256

Comparison of Solid Phase Extraction versus Direct Analysis of Hair Extracts for Cocaine-N-Oxide by LC/MS/MS

Crawley

P257

Benzodiazepines in Oral Fluid: Effect of Screening Cut-Off Concentration

Coulter

P258

Hair analysis for estimation of exposure to methamphetamine and its related compounds

Nakashima

P259

UPLC-MS/MS Analysis of Drugs and Metabolites in Hair

Boone

P260

Screening of illicit drugs in hair with a combination of enzyme linked immunosorbent assay (ELISA) and enzyme multiplied immunoassay technique (EMIT)

Powles

P261

Detection of Phosphatidylethanol Species in Dried Blood Spots by LC-MS/MS

Faller

®

+

For more information and to register, visit: www.toxicology2011.org

22


Scientific Posters Friday, 30 September 2011 12:30-14:00 hrs

P262

Alcohol/Biomarkers A Study of Blood Alcohol Stability in Forensic Antemortem Blood Samples

Presenting Author Shan

P263

Chronic excessive alcohol consumption diagnosis: comparison between traditional biomarkers and ethyl glucuronide in hair in an authentic population

Morini

P264

Ethyl glucuronide by LC-MS/MS: Where are the limits?

Weinmann

P265

GC-MS/MS Method for the Measurement of Ethyl Glucuronide in Human Urine and Serum

AlSaabi

P266

Carbohydrate Deficient Transferrin: an Indication of Risk for Car accidents with Injuries

Bortolotti

P267

Detection of Ethanol Consumption Biomarkers (Ethyl Glucuronide and Ethyl Sulfate) in Saliva by LC/MS/MS

Guice

P268

Carbohydrate-Deficient Transferrin (CDT) as an Alcohol Biomarker: Influence of Age, Gender, Liver Disorders and Antiepileptic Medication

Loucka

P269

Assessment of Alcohol Intoxication via Visual Observations and Blood Alcohol Concentrations by the Widmark and Microdiffusion Methods

Uria Huaita

P270

Ethyl Glucuronide Concentrations in Pulverized and Cut Hair Samples

Albermann

P271

The Effects of Chemical Treatments on the Detection of the Alcohol Consumption Markers Ethyl Glucuronide (EtG) and Fatty Acid Ethyl Esters (FAEE).

Rowsell

P272

Influence of age, BMI and seasonal effects on ethylglucuronide concentration in hair

Salomone

P273

Alcohol Intoxication During a Drinking Experiment Based on Widmark’s Equation

Gnann

P274

In vitro formation of phosphatidylethanol homologues after incubation with d6-ethanol

Nalesso

P275

Evaluation of Phosphatidylethanol Concentrations in Drinking Experiments

Gnann

P276

Sports Doping An Analytical Method for the Determination of Testosterone and Epi-Testosterone by Liquid Chromatography-Tandem Mass Spectrometry

Presenting Author Taylor

P277

GC-GC with Heart-cutting as a Simple and Rapid Sample Purification Method for GC-CIRMS

Brailsford

P278

The Effect of Ethanol Ingestion on the Reliable Detection of Testosterone Doping in Sports

Vicente

For more information and to register, visit: www.toxicology2011.org

23


P279

DFSA Importance of Packaging Analysis in Cases of Drug Facilitated Crimes

Presenting Author Aknouche

P280

Opioids in Fatalities

Ojanperä

P281

Detection of GHB and Related Substances in Urine Samples by Enzymatic Screen Followed by UPLC-MS/MS Confirmation

Keller

P282

Gas Chromatography- Mass Spectrometry Analysis of Benzodiazepines in Spiked Drinks under Different Storage Conditions

Gautam

P283

Urine Toxicology Findings in Alleged Drug Facilitated Sexual Assault Cases Over a Six-Year Period (2005-2010) in the City and County of San Francisco, California

Williams

P284

DUPLICATE

P285

DUID Profile of a drunk driver and recidivism risk factors. Findings on the prevalence and development of drunk driving from roadside testing in Uusimaa, Finland 1990–2008

Presenting Author Gunnar

P286

Phenazepam in Finland

Kriikku

P287

Prevalence of Licit and Illicit Drugs in Whole Blood among Danish Drivers in West Denmark

Andreasen

P288

Benzodiazepines, Zolpidem and Zopiclone among Drivers Suspected to be under the Influence of Drugs

Donze

P289

Driving under the influence of hypnotics and tranquilizers in the region of Bern, Switzerland – case data and a novel LC-MS/MS method.

Bernhard

P290

Analysis of cannabinoids in total blood samples by immunoassay screening and UPLCMSMS confirmatory analytical method.

Castañera

P291

3,4-Methylenedioxymethamphetamine (MDMA) and Metabolites in Oral Fluid Collected with the Intercept® Device and by Expectoration Following Controlled Oral MDMA Administration

Scheidweiler

P292

Driving Under the Influence of Drugs: The England and Wales Perspective

Button

P293

Do DUI enforcement procedures miss drugs when alcohol is present in driving under the influence cases?

Lillsunde

P294

2-Amino-5-chloropyridine – a Potential Marker for Zopiclone Degradation in Forensic Cases

Nilsson

P295

Comparison of Illicit Drug Consumption in 1999 and 2009 in Individuals Suspected of Unfitness to Drive Due to Abusive Consumption of Drugs

Augsburger

P296

Proof of Concept for Automated SPE/HPLC/MS/MS Methods to Replace Traditional Immunoassay with MS Confirmation of Driving Under the Influence Samples

Sears

P297

Relationship between drug use and travel length among Brazilian truck drivers

Sinagawa

P298

Methadone and Driving in the City and County of San Francisco

Medina

P299

Felony Driving Under the Influence of Alcohol Cases over a Four-Year Period in San Francisco

Knight

P300

Misdemeanor Driving Under the Influence of Alcohol Cases over a Four-Year Period in San Francisco

Volk

For more information and to register, visit: www.toxicology2011.org

24


2011 SOFT TIAFT 2011 JOINT INTERNATIONAL CONFERENCE & EXPOSITION ON FORENSIC & ANALYTICAL TOXICOLOGY 25 – 30 SEPTEMBER 2011 MARRIOTT MARQUIS HOTEL 55 FOURTH STREET SAN FRANCISCO, CALIFORNIA, 94107 USA

www.toxicology2011.org Information contained in this schedule is accurate at the time of publication but is subject to change without notice. Please contact the 2011 SOFT-TIAFT Committee for the latest information.

2011 SOFT-TIAFT Scientific Program  

The detailed Scientific Program of the 2011 Joint SOFT-TIAFT Conference on Forensic and Analytical Toxicology

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