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Datasheet of SYM2206

Description: SYM 2206 is a novel, potent, non-competitive AMPA receptor antagonist (IC50= 2.8 μM). SYM 2206 exerts anticonvulsant effects, elevates the threshold for maximal electroshock-induced seizures in mice. TID20 and TID50(threshold increasing doses by 20% and 50%) values for SYM 2206 are 4.25 and 10.56 mg/kg in the MEST test in mice, respectively.

Chemical Information Catalog

DC8308

Purity of current batch:

>98%

Molecular Weight (MW)

366.42

Molecular Formula

C20H22N4O3

CAS No.

173952-44-8

Solubility (25°C)

DMSO

Storage

Store at -20°C (desiccating conditions).

Handling: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months. Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.


SYM-2206|SYM2206|AMPA receptor inhibitor