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Datasheet of UNC0224

Description: UNC0224 is a potent and selective G9a inhibitor with IC50 of 15 nM in the G9a Thioglo assay. UNC0224(Compound 8) also potently inhibited GLP with an IC50 of 20 nM and 58 nM in the Thioglo assay and and AlphaScreen, respectively. 8 was more than 1000-fold selective for G9a over SET7/9 (a H3K4 HMT) and SET8/PreSET7 (a H4K20 HMT) in Thioglo-based biochemical assays.

Chemical Information Catalog


Purity of current batch:


Molecular Weight (MW)


Molecular Formula




Solubility (25째C)



Store at -20째C (desiccating conditions).

Handling: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months. Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20째C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

UNC-0224|UNC0224|PRMTs inhibitor  
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