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Datasheet of OPC34712

Description: Brexpiprazole is a novel D2 dopamine partial agonist. in vitro: Brexpiprazole (OPC-34712) is a close structural analog of aripiprazole and shares some of its pharmacological properties. Similarly to aripiprazole, brexpiprazole exhibits partial agonism of D2R and an enhanced affinity for specific serotonin receptors (e.g., 5-HT1A, 5-HT2A and 5-HT7). Currently. in vivo: Brexpiprazole is in Phase III clinical trials for patients with schizophrenia and as adjunctive therapy for patients with major depressive disorder

Chemical Information Catalog

DC8286

Purity of current batch:

>98%

Molecular Weight (MW)

433.57

Molecular Formula

C25H27N3O2S

CAS No.

913611-97-9

Solubility (25째C)

DMSO

Storage

Store at -20째C (desiccating conditions).

Handling: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months. Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20째C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.


Brexpiprazole(OPC34712)|D2 dopamine partial agonist