Page 1

common words data disorder Molly Hawthorne, Thesis Presentation 01

August 31, 2009


ception (hallucinations), language and thought p (delusions), per ht content or scars. An example of a nonbizarre delusion is a person’s fal rocess (disorgani zed in thoug se belief tha s tortions ving any wound . Because of the difficulty inherent in developing an objective t he or sh speech), an is d e de ia en lud ut lea hr c o p n e vir h he o t nm to e ty in nt zo ivi , it so ct a m hi re ) et w imes reaching finition of “though e is under s d self-mon ease in A4 ns cr of S c e – a d re 1 ed rg urve t diso tu an rk itori A a o a e m xt tiv iteria one else’s important fe A4) include a persist in goal-directed ac ities. The person may sit for long pe reme degree o rder,” and illance by ng of be s (Cr e st f ri b initiate and rion ptom with som single mo viors (Crite y an inability to ot attributable to the secondary causes described above be re ods of time and complete un ecause in the polic havior (g n re a m at y th es the em beha ymptoms ized b drift”). The majority (60%–70%) of individuals with Schizo ferred to as “de show little awarenes a clinica e. Delus rossly inte ositiv laced th me to be ic motor character ng negative s parents (“downward phren ficit” di io s ls bulk of their time in bed. Suc is o p he p eir uri and they may spend the ton h negative ia do not marr symptoms rest in pa (cataton etting in ns that sorgan n. T has re ed by sle. Cata Avolition d that end level than th e and inquisitive; ic y, symptom rt i . e io t sms, ritualistic or stereotyped behavior are sometimes p . r ri tiv u c d e e b ne s a t s are o and most h Criterion icipating stupor ference xpres zed or w n s an s n m an rg nda talk d e lo u io re s od a g f t a , s se s ft ) pr s e e ce g e im d t A a e et ng n l l m th a o s e e , s n c ri t. o ns a u ay i v n et of Schizoph ta e tu tu s rder m renia. Whe The life expec the first sig e relative for Schiz n work o mainta about a loss ataton rma rgan bee ders ing, pos loyed een of si becom sonality Diso ased basal ganglia size, but there is i t ly th n a o f no rnal o r”) has n is un variety It has b are emp they may (e.g., grimac or Paranoid Per r i e nc n er n cr r ea in i p c li s n si of o t t he y t n o hren g evidence ocia g a though of con ic be of ind se Pers the fa mited is tha n inte rde atio , . ; d d s d te i s a e a o e n o i i e d of ai v s ly lic ie i li it vi t iz it a ng tiv iv c l ha a t a p l r a ti n s o well as the abili soc i igid t ar trol hav mily idua r t this m act nality r v re o bo f time tivi bnorma ypal, Sch nia have with ntly re isto r he t dis moti and ed a Schizophre le ac o onsiste a ot nt Syndrome. Spontaneous motor ty to acquire skills ay be an ep Disorder ls with Sc that so ial cont quires ivities. post e bas over ior). T s are met or d his o ough if the er time escrib eriods asurab a. Motor on. Schiz has been c individuals with tonia, and Neuroleptic Maligna acts that min he e abnormali iphen hizo in psyc Alth ure s h t ti d le i de s n n c te p y h a t e o e s ys ti v s o y d . ve v p ha a o a dp a es r i y t di n D d ag h p la i m n ma xce move rmal eciall tion o auses tained iously izophreral popu finding th ulty that so duced Acute vidence that clinicians onset cases tend to be simila nose Schizophrenia in resembling th osocial reh menon of mply pro hrenia i g is w The dy t least ough nd re rimar or b e pos r c s a s r to earlier-ons p c v r o h Latene -In ee et Schizop some ethnic g ose that m abilitation treatme dromal shorte ong; fa sfunct two o omm sisting ily on ody a itive t a as re g (“f ia, es bserv ential for su t in pre n in Sc he gene . Anothe e of diffic euroleptic There is som after age 45 years). c m is u t c h se n l e o ss n te c a r l a f io ommon in men. h s h . in o p ot n hereas .g., le mo e to t job eres Women als renia, althoug oups. Stud y be indu . Accord t with ty to Schiz r than mily m n pe the fi on in effor the in re ge ymp degre t this isia, N essed et after 40, w n life (e ref er ink re ire S ie th rs in v o have b h p t e c t n o d to trang d th izoph requ of the hold a se int re comrelativ oked a d to the ute Akath refully assbegin later i e an age at ons etter p a number s conduc ed by n gly, the ical ne phren at of t mber ists f e item chizo s to b ividu eral oms e h a ar a lo o av c remorb euro of dif s m or a s ted i ia o he urol ph e m al’ ly c ma sev pe at a s aniz f Sc t may each ble to they l obias hrenia have re relateuced A lso be c can also of women h p b fe n g l e r r e id e a th org e o tha ng renc d the U ptic h izop dies ey a ; ptic rity a t a hrenia whe ene ay u sub e p eni ov s sp ons y c functi % n s 0 n p I n s u 1 e – i u f c w s c s o h a e sh re lti oning i ra nit m id o s f t m ie e ( lv nd ch n 3% , n m izop tt e pti stu ra nt than ave be ed Kin e.g., sn neuro edica her th l pop mate tantia sent neg d (ca ech ere mpr pto bel A. D vide gme t reso als ar withd iety a with S fewer l in tha emole f volitiood. Sch ximately p , d e is e ly a g men u t t e d ym n’s on a u fu nx ls ,N so pro e ho ut . Wo n obse dom a iffing, sycho ion. A y con lation repol peri conc tive aton the c to b e tw e s erso riteri to be cal ju cted divid com ns. A vidua es, b aning onism rbanceof child en. Ap t r s o u n l n m i s o v v o c r d i y e d t n r e f g i t m e s e i i t d. F nw the gue ica ncr tute or a tha du ren mp rig onc e bi o di g si a p fy C red clini dire ny in y b ortio ind elativ lly m arkin distu rders n it o o za s e e o ld tl h Sc U id t r r t c a v a p is a ma rop d in e r ica d P is e a ts gs, iso dal am hizo exam nited luckin efici sed sep arie they ing t y for oms ity), pt of rre; tinct re lin he n sat sid k, for l. M e o l p te ttin n d ce phr ple, Sta g, g ts is inci ara ty o ex he mu are ac di th dim . T lusio to con pea ite ef hoo activ iona leva t-deg are c Indu se se mmo t unim t e c p e f t d t e t h c n a e ru s o d i so es r e e e ia t sc lly lus re e firs its tic ver e co bu tiv e ed be o s p end prop sugg nting relat nce earl easo rien urse h of iffic ve re rga e in ensi ga e d ed ot s t des ish cia de r a ed efic lep s di or life, to e ortio est ) ha ively of la ier d ns. ced of at l ult sis nize clu ons ne izarr s ne ld n nes me o fin n so ach orde ffect se d euro cros ese m ter in t t S x N i u d t g ti a pre n of hat d b stro rge isor uic the he eas to e tan d s de , w h e s e a e a e v c S an a b om sho illin of ble be es r c Di ir un . Th sia, vary n of t ring l d t d ss p a h mo affec chiz en d ng p cavu er is ide i indiv isor 1 m alua e to ee pe ich ive le of mpt ior unw riod una had etim Pani the renia skine d to ratio ccur t re ted oph esc red m i no s an idu der onth te b ins ch ( rson ma s p sy av an pe be ho m d d ph Dy cte ide k o a s n o w i r r f c t e o fec om en ibe to al an . H e tru Cr ’s y n a a izo ve pe ns ea p am le eh m le ay s w p c i m a : c i l t a i r p t i o a e s d b d r b ive en l h rd ex c o a c ite b in s d o um a p ies ex ing d fro ra m a an de en c e nd Sc is g may in th f so pe r. A orta “gr doe wev use tions rion elie turn or n s s ate d ide ual idu ur or phr or S d Ta be du co hiz re be e cia llu n i nt ad s e th o A f t b p eg s. A thi git tiate ons ivid ndiv occ Dis hizo rs f uce canhout a se n o a u f t c l ph ter dia ren an id cr ac al not r, if ey r a 3) hat e r ca nce nly or a ren a c ind e. I ay sive Sc acto Ind ivity wit with ren , a gn eu d i h ea to ly ap de oc tte ha hi el ia nd os rol voc as sed r, b slip pe lus cu mp s s o ate ad rie n o ry, iffe for the ver s m pul with lity f ptic- act enia en, o b an in ed ep a al e e e br xp , th ang e d ce nd e se ernCom als rabi role cted phr wom d O div m tic tio so risk cau ping ar t ions r on ts t een r he d to b en , a it nc o o e t u u , e r e z t the idu ore era nal be of se aw o b ar a c o b em r th di i r n tw life se ss us ist d qu co ive ivid uln Ne -di ch l fo f a e e e e o S a o r s v de al S da le s te e to Ps ls w fte an utc n d ch pp ay. a bi ont m ph oug fere o to o in ry re st m er p b tic es ind al yc ith n i d a om em izo ro ” A dir za in ov as h nt g na e p re his r p sru en ma bs th ve clu , g d im h o la n xim s ec rre uu ed iz ts u r p o e e i ll in rdi a r s of h. T hei y di oft so f O bo o re nt in ted bute is b h n ti c t e n d a . S s r m e h n s t fa o ns e c s t tl an nd s o in , t e itia ttri on Di on ivi lso ev tra eni ate oc res or h wi (ca d in ave der so se du st er te a ly ia ul a th ta t b ly as from tio anc pee st i uen d c n, a rate ved aps atm lf-in e a buti rd t a al ill al d i ha 10 t t o llu n to he e na inst of s t te freq an tio ar, ser erh c tre f se ot b istri er re s w ob ne n s % ed f ci or ni d i a n m c s s m h s u in be o c a l s i w ity be is ses aliz ticu ob d, p ept ng o ld n et d ym or o a erv rop div en f in Fe ny s atio ali n tiv he ess ha ere ar een an rol ani hou ons pt e l re ed hy idu fo di at in ns ty t r l p d p b ss eu e s tom ike A , a si a u vi u gl i g a n n o ua n, . I lso lne o n l m ms eat ly fric lth olo ls w d dua re e ol to an ou gi it in ls s id tio nia a il y t ura to ag og h c h za hre has the dar ult mp he y, av Am gh al a Sc ass w pa e b er the b h e of on e c sy s. T m es ec th se 0 ra ee ica y no iz r s se he -3 n oi n m n a ma r e au . T id d de arr nd c er ) e m h l u ie d t si d

is of Autistic Disorder (or another Pervasive Develo p m en vious diagnos ta l Di sorder), with a pre he or she is being tormented, followed, tricked, spied on, the ad ividuals o rson believes ). In ind common; the pe st occur in the context of a clear sensorium; those that occur while fa r ridiculed. Refere ditional diag and E lling asle nosi ntial st ions mu prodromal and residual periods o f s S he d at t ep c hi g zo in e o rin p u teria D lu ( arc mo hr d hy f r en u n (Cri delusions hts. The halluc h may occ e.g., anhedonia) are noted in the “Associated Features ia (see Criterion C pnagogic) o sions are a Schizoph ( nditio r ug or speec l ry re ) a al co ersecuto n’s own thoized thinking negative symptoms symptoms and medication side effects often depends nd Disorders” sect . Grossly dis waking up so comm nia is w org on edic r on c P io (h n ve a o ral m ndiose). the pers re disorga ophrenia; othe etween true negati n Disorder should not count toward a diagnosis of Schizo linical judgment n below. Affe anized be ypnopom ; the pe rranted con ene rs cti phre ha a m s seve iz o p nicatio on b r a g o r gr s ct fro of Sch a Commu istincti re relatively mild or subthreshold forms of the positive nia unless the de cerning the ve flattenin vior (Crit ic) are c on belie nly if p type o rom ce o ous, s distin ation. Le definition ning. The d in a child with residual symptoms a erion symptom gree o g is e onsid ves a s sp fd fa in ic stan eligi s t and e A es of psychomotor activity (e.g., pacing, rocking, tte ch sub atic, r rceived ommun ed in th ective fla ized spee e prodromal here are abnormaliti behavior. The major predictors of violent beh or apathetic immobi ecified in Cri isorganizati ntipsycho pecially 4) may ered to hat cer ent de fa d avior are mal c terion com m e lity). Diff on is lusio tic m olent be w tain om an en t ic aff eg ts o l, so tive A. inclu m man ltive and vi s ic re p w it. S isorg e efs. Oft also demonstrated decreased brain g ffec ntia that a ir effec n—are may mim le, the d may follo usional beli idence of assau tricles. Many studies have tissue as evender, younge ulty in conc Individua ignifican dication on and ifest its ithin th estur ns or ra tl e ven a p e s e id ls r, t h al e ere el io nc deficits are a consiste , n l y e t al e n is g f f ca in r s di nc m a n e tr t a m g i g in h e , e , a a r g d p c ro il r l a r e t x a u imp volit l b a io ptom e ps c igher i gic y , tha h lf in e of d the late ircuitry. Neuropsychologi ase (CPK) levels may result from Neu of individuals wit y widened c st history o n, attenti expres ater tha effects aracte a var nge o omm ucina olo utory, unfamntially and a inesia s. For e ual sym sequenc a have a h rgement of rtical c i k reatine phosphokin ysi ph rsec liar or ubsta logia, brady ifficultie nd resid s a con izophreni to be enla cortical-subcoances. Elevated c monly held in another. In some cultures, visual or au roleptic Malignan h Schizophre ortical sulc f violenc on, and s a varie n wou of ant rized ety of f norments, tions ld t Sy a ditory a e, p ic i a b ia s m nia w h a g d s bal es t a ect pe e com dir e.g., r fam gh to ning, uch a ental hase, se food with Sc continu es involvin lectrolyte im itchcraft) may b renia typically occurs between the late teens and the mid-3O hallucinations w ndrome. As . Deficits nd decre noncom emory y of un be ex holine y the ays, l exp assa re pre e p per ran eri ges se g s ith a re w sociate d e u s, with on ( m ti are e r u oph he te ased plian is fre usua pec lig set e g s o t mes heth eno e flat fects, velop active ay ref agnose d findin bnormali gravity or sorcery and e onset of Schiz te gic v n d o anti psychotic medications in lower doses. Among t et w ere ctiv hose with prior to adol ious conte physical ident ac volume ce with quently l or od d on medi on’s f ing fr nce. from t for responsive t ef r de the or m ls di plicate read a pecific re (e.g., ations. Th du the s, c es nt be quite ro a I th t s e d o slightly higher incidence of Schizophrenia has b a a b s h ay A e c ee s n ). p e m n tu en l r o d of s s e m b ot ice sev affe side rs o r to l ting idua r u s e a er o e f ved in m oldest age ence rare may be axaminati ss a ran of gray ntipsy eviden belie e ba ations ce ap m ch olate ooks t lea s n riety as vost be s— idal orde t prio t in ea f indiv istently re wid s in urin in one c dustrializ gh individu more like that on sis ato en tha fs ch (alth ,a ild t. st ge p no d , a l s f n m e u n e o s in A n di n i s m s i n w omen set (i.e., o ough ca rmal pa indings of cog d whit otic m majo that a of th nd d arin like s expenews a m an a va ced mu pto yra er d rese tere ups o t con est m rmaliti lusiona uals in nic, altho d, become g e . Furth rt o r o e a v s n e res de ien tom sym trap oth n p of in bgro mos sugg abno e de ndivid y chro l perio er, a er age 6 es with of relig nd gen itive a matt dicat rity of e not Com sage imm illine rienc pape nth atu clu er mp ative ce ex ce of e ofte lack at su and udies velop ear to ban do i typicall nopausa num 0 ye age ious eral bilit er. H ion, es rs, (Cr ind of d mu ad ob ss r e d b e h a Fe in xp sy t h a t e i i a r o o n ay lly e he neg odu sen s a ow ed t udie nt s nd d y app me t urse is postm w f s rs), s at on exp med ies, d ivid elu nic jus le a o u of so ter tic e r t tu e s p d th pre tom sh ort ma utco e co ece ”) a ho t m ua c, t e ies hensory set of erienc ical co includ ver, exce uals sionaation tmen nd u npre hear ng ly ion F the wi 5o e( yc ten us cifi Thre ften the ymp may rep idely ore r ation that tter o g. Th ially in in de nd d in ts av D l s n ri ). s p e g s c e e t i f e l o in w c s r Ps on o d pe r. emoficits ( r 6 ye e.g., s itions mem re is ive s h Sc ropo isord . The resp ctab g on cs, o The al dua hav ost the m toxi Ideand a b nction n, espe ith c s a ns de ns n o e nstr e.g., ars h eein . Ind or ong ubs hiz rtio er l a W eir on no sor atio atio rom divi ies e m of er in unt. l fu me o y a dif ns e a ’s r o ch ate er Th inati nd e di dic ider Prod e in stud e, th most (“wat acco ourse socia or wo d g audito ave b g the ividu , psy oing tanc phre ns ( lone ficu ive, gita nam ther ara a e f r rd s. s c h y l e n so e luc on h th c m on e). ). T an ratu and luid into ute t and ome d ry a een Virg als cho con e u nia e.g . S t d wit tio e c en cter e s t c i s . f w n h c i c i s s n , s m , M c v e c t r t Di nc al f t a d iffe d vis repor in Ma ith S oto rove e. Ho have idea hizo tinc poo . Pro alled iron istic d rie y h mm w ho due ph snestion. ng lit gion ts o ence ore a f affe m ou r re u c te r n r r e e r o i p tio r m s m oo e or co ed yc s w s a a b y p h e n t n c M xp it s iat s de tiv les ula ag n r ou iffe a es l loss d). T or h izop biliti y as eve oor of r hren n b eye lem or e en ym a r e ud h i oc ntip clu ac est op im rai am l d ve atio long e i n t ) o he e e r e x ta p h i or s o . A ec ss a in he or r l p uro e b ive ltura o ha eserv but he cc es arin reni s, a to w , it s nsig fere ia in twe con s ma per l cu tom r tte he ho h a ge ur se g er on on pe y a ain ld (t y era ne on ss cu d t n vo e ta y ie e s n, n rd ti m s dit ert hou nia ivit en ral n}’ xce ke ten ith p ome eti mor ntial God are s ntio ther uld t reg ce o lve n ne ct a be nce s a of w w so ep om ed bi C s re ct g tu o a e ta s c t e c fe ’s s n ran om atu vo ome , an the be n ard r ma dy gat nd not s th re s Sch Di erc st c aniz mor gia. oms oph e a the truc ed t rink ust ation oms r in d t in ic s iv re e a p iz a d s t o r g m i m ive f p o rg e lo pt hiz httimve to the s limit nia wn mng n mp bette iss onl es o e). I mes diff ppa ted g th ica func e sy duc d in t la ecif oph y i ct o m o th a m c ion y t f th n a p icu ren th e f l th tio m ed an ck ica re fe n e is of and sy of S nigelati . In be phre eir oelop ve s e is af tio r th ly d e ic A nd k r cts to izo th ev siti om of han e c ddi hys lty t d at m act ink n i pto b y f the lly nia zo ta a ld re n, st a ic i o S t e i n m o o c hi pre y f mi eg litio teri rion ay ris bje ikely Sch from in d f po outc hiz in th ndit ion, ally n ch cre ost that ng) on s a dy rm qu dire inv d o c e d d u l o t a Sc er b e op e g ion the aw an as ind th ; th e o nd lan of ali ct ol y int are us tial av ara rit he ase ol s un with ren eni nce term hr e e r iv e g go ty o ed ve a a k g e y n i d i y e m r n u w r b is s ca an n, h t C t re ntr are ls ffe hr a mn i s n ia. eral e th ses ard g r br dua hav ma or epr ag al- f a at a ra (o a m tion Be bst atio he c ee ring inc co ies ua e di izop omin diu Ra ad e s sm a esp ain ls e y h e m es e. dir n e him n ed e a ). u ol f t t m du at ed lit vid ar ch d me n w a a s A e u t e nt olv cin lad” a s al is n o tha ng are tch rma indi hat th S pre - to s o lt p me ent d m ons tiss ith ps ave ajo ive lth cte xter o nv allu sa for oci atio ed) epi ps ma no me ns t wi y a ort f S op in of ay e s ue Sc ych un r a sy ou d b sh h d nt s u t le u y ab o o ls c di d e is h o u re m g b c u i l l l h or ou ic va trea ., s gro ate nal t. S uat idua ized .e., izo atio hild sor isp t. In a izo tic su as pto h c im , e ly .g th ri io en sit iv er (i ph n, ren gan lay ad foc ph illn al of m en ful (e bo rop ct tm al nd act ge re alth , b iz n d al ren es pe fu r I n n dr ess tern ut pp t fu trea ltu s. har ith a i a oug ut i ed euro ition as ia a s. E rc am h t m sp lo t op r c at s, b d a ha ts cu trie s c w p e n t f i or n i e on th a ee gic o th po e y al ia a tion r o ic cou rse gre e c s g f a i r s p b e h m al “ e p n ni a o om rn ou de m e pa a so g ni n t e c e i l c y r y re co es the om m ific ticu oe -W en o s em ro n ft t be l O ate nu

period (or for a shorter time if successfully treated), with ing a 1-month s of time dur s (Criterion A5) include restrictions in the range and intensity of emo ome signs of the portion tion t om d n pt a m y c i s (“delusions of control”). If the delusions are judged to be bi al expression (a isorder pers ive e rc at ignif fo g s e e id a N ts . r ffectiv zarre, o isting me ou vior t fo answers to questions may be obliquely related resen h and beha anipulated by so or “loose associations”); or complet nly this single e flattening for at lea p n ci ini an cl s e h th ou , t” c ld nia e k e e hr ep p sympto ), in th in mind that c ely unre st 6 spee erailmen e be on or m ted with Schizo t hav rganized ing acted to another (“d ally been associa judged to be dearly attributable to any of these factors, the atatonic symptom lated (“tang m is need e fluenc month ( a h t Cri entia s are ya n it sho ed be iso oric pic ptom is ve) gati cludes d tions are m one to tonia has hist a negative sym ” In those situations in which the active-phase symptoms remit within uld not be consi nonspecific lity”); and to satisfy nd prod teria A a e n : in r ac k” fro cata e phase. on). If and es (usually in multiple domains of functioning). Some a month in resp dered in ma and may , rarely, s Criterio uctivity nd C). ive ension r body o the trac Although emoralizati to as the “activ ve pattern of difficulti o si p o of th k g n The it ns i c se e n s c h ic is o h w o ne g s), e u of f ul th t e defining featur ur in o treatm the distu ff o . c nA d the d asi im e riate stim d se s es of th oth h ma for Sc oug rba ia th p tion d is or h y “slip o itement) lation, or s is referre is a more perv absence of an approp e a h c u (bo a e male gender, being under 45 years of age, depressive s e Disorganized nce must p nt, Criteri gnosis o er men y be so hizoph ht and igns a m o f ymptoms ms rganiz or that rson m tonic ex nderstim sympto nless there pression in th rs for suicide include aboratory findings have been identified e t Ty n S rs a r s o p c l is A t e. Anh hizo diso ever enia. speec nd sy t for a l that are diag d x u , feeling o p can u e No , to e n . ta c n l l ) gs n a p is fa a a o ” di i m a e in k t f p e ri c n s c d s r d y m ostic of S s s ( n “ ator sy he en ic ri rite y fa functional brain imaging studie ion chizop of hopele onia is c continuo till be c hrenia ders, ly dis Halluc h (alo ptom s, h nd s the insert ays. T activity vironm on of sigfor this c g, or a sill pan, specif Associated labor with Schizophrenia. In terms of a sa s n ti . r n als t pursuit and saccadic eye movement ypofrontality (i.e., hrenia. How ssness, unommon a us peri onside . For ex in gene organi inatio gia), s a w ign where ough ty of moto sion, e nstella vidence , laughi whole life childhood) up of individu y gating), abnormal smooth re o an a z s, e r n e n a s e d v r re lo s d m e e a o ic s, nsor individuals are more likely to develop cigarette rela wed reaction tim lative decre r, a variety ploymen is man of at le d to ha mple, l med d tha s (Cri d in asso (“th varie ssive epres ere c ient e smiling ver the in early n a subgro n rist ent in se t te t t ife hrenia, these a e t a cte inatio r mind d in a exce cts, d ly sev t suffic t (e.g., s high o infection , at least i .g., impairm mon in Schizop l insensitivity. Cultural differences have been noted in the present d pathology (e.g , alterations se in cere of meas t, and re sted b st 6 m ve bee he beh ical co it is nerion he ini ciate a r e at m o ., emp bral ure nm on ion, co in bra ce ya av nd ea A2 tia d w n ffe ain uli (e ze o co cultura tiv ted ality ffec ha luc he tem kocyte antigen subtypes, and cerebrova f c hal is or rgani imula side e is rela lone is riate a isk rem us sys abnorm nsory stim ndence is s nician bias or state, human leu scular dise urse, and outc hysema a in latera blood flo s from n nt hosp loss o ths (Cr et if t ior of itions rly in ) ma tion o ith m al us o a p er b o m f u re n o li r d no h os by n pitalizations and h iso nst on re an rain erv rop he lt of c f th is a postme Depe n men, as defined of se lengths of ase are possi ome of Sch d other p lity, and w, met euroim ital dis f intere iterion he cli an in , and compy occ f goa arke d ixtu ns t into be d nd u dicati nce o er, th inapp ough t entral n ental b essing Nicotine re the resu such as the ter prognosis tha n b a hospital a c a u stay, ov le risk facto izophreni lmonary bnorma bolism ging, harge st or p C). D ician ividu Med rehenur in l-orie d so y y e pm ya lt h tors a bet a m sio pu roc se ,c se sa ill h a. C neu , or ica al rs. Th uri erall d .S ci ju litie le an s an n re delu een ia ma eles s, m e pre to k displaess. A ations develo and p , becau ether the linical fac omen have a u ra tion o e clinic atatonic d cardi s in ev some ropsy uicideasure ng th dges who tion ible a y se ted b al or ia des ve b ren rpos ptom . Th rying may e illn plic line eption ample or wh lation. C renia, w n a h f illne a a . n c t d u ps om mid m re lu a rc th oph ia pu ex ph ss, timl presen behavio c prob oked p other p holog risk i Dysp t tim that t as th Induc nd re sory ehav occu ph inc ts h hizo , or p ve sy quire oss is hren se of etric c atal) the pe s. For ial grou eral po of Schiz s e h ta le o r h i e o r s e e e c a t o ti h m p o ” h c e e m io pa o to re a c a d x ) l iz en ti er re r b izop our bst pren s in se laps n is mo s beens). Sp ntial e y for l, and so eleric m eriod symp delus Mo mbl oda r (av tion e ord ng ra he g cour c ch ion oug h S ing osi is o it , h e, re re li f S ens n th wit stur ng p item hat h h Sc r the ine, y (i.e. defic ed dis s amo ted to t ing the rep ecif lectr neur ne vat ood , th tom ion vem es r lity olit al d o k s l t t t s m e o i u o e e e m o i e p a r s a l e d ic ly r e e (e io r r s ons e y d m p ud ne on l w ov l fa ea a ar cia nce es di li tra gar e to to inc ted as Cul ncep activ ophy dur ay t e mu wou l bel nt D cept .g., n). D sfun tur tic at a vidu nic incl ly o lusi ua pt re to f an mon asso iffere n con l). Re neu lud rela tur hal ity) siol ing ake st b ld ief t iso ive au el ct fea cho ), th indi atato rs ( of on d de divid attemposu ive o com ently rue d whe rawa e o o r h p c l t o lep per ivel e, A gra on gic os the e a av hat rde aph dito usio ion a sy al” of (c cto e be e in ne ex est ost qu nt t ired ithd i t s t m y tics e t a ( r t h r i p i c n l a o s g e m o fre rese mpa ial w , an ecuto uncoge, a s. A nues l stu psycform leas per e w s. Th asia y, vi ns ( Crit se e “ raw ch re r f en scr . Th st ata ug i t ep oc d s ry d mm nd bno to die ho of t 1 sis ill b e es Th thd pee stu the res um ers t lea ren is s g th ted r i s C e an d , s oci elu on G rm be s h tic de m ted e ne n its ual, riter rion he tes. t wi e s e po of othe p circ isord ke a flu, p se it mon rela dings ated olition a g p o e a i s i T a o t p a l n A h h i l r y n l l e r h a a n d on m nd la e ve e r e th fo d t in lfa on B). s: rela ug l. T zar riet en f the tal d ma e to cau nia. y b e fin iso t, av wo s an ong er bora mos sho iodsssio of r a m ang ive s guis cto A1 Th re cor “tho nua r bi a va ,” th e o en 40% sur s, be hre s ma thes cially affec rk d h ind Fe to t c wn . M n, sy o er ym tic ry ) a e d u o p m t s l r o ( a g o , f g a n r m n i a r un a at ica ce m te to sin cau nd and l exp atio hizo ndin ethe re s s (fla cti lluci vidua tu y fin onsi diffe ales nxie pto th i if he pto dis gus e e istu h mo m on na n r r d s Fe lin for his ria ue er be s a ta lic Sc fi ing tio ls w es ing tent ren suc ty, o ms the lea ms orga tato ron rba c d c de in t rop e d onv job ture 20%ena imp ith sical ver, w ess mpto i c : v o . H ns, ith C s m ly p n r e n e c r (o st s an utsi sed ap ay b es c er fea een ., pr ical als w phy owe thel e sy ow an Sc lini ay rep s b ess ang r le abs es h f Sc iza y, a ous ce i o h e e n n v c h e s s e f t ev d h l n sm e o a u of i d m voic its ptiv etw (e.g log vidu her r, h non ati er, les izop ians also icat twe ully er. T s th nce is ro izo ion d ta bel no i o the s li hr as be ed en co he an o om ph (“ ct ief t b ag n m ni n an r “ qu cri d b rs si di Ot lea re neg e i m f k i r r f Di cha y so hre ptio ic, ” o an des an cto phy of in cts. ot c ey a ore n g s l n i e 1 e ge ely ia es no nd ro p m m ef o n c e) s th ett n p a o if g e e nd to in si te in up let a o fec r t ia oh , b at er m y b izo um ec tin om ted e— d f ath ps eff t is t th s m er in th ng d a g. s e s y nt ti alk (C er ut u ac al wa ch ass sp en a w cia icid hoo t p grou tic s. I t, bu pres r ad clu e U th s Ho of ui be h i ve s rit en a su c u a r S e on m , if so su ld tan n lep up se ex va de n e s a c w in cid d f s tre to er ce ud all ou e n en fo th y n om le As it chi or d i o gro on to nta d ite ym o ev div e ist ym a an io ” ito y , l c p m m g k p e ge iso d S p mp er, idu mo urb p tme yo n A or ry i in ta tion sm) tive es am rs: om nd im trat ne cial e at end i n t a i c c x e in rga tat tom lica the als re an tom nt ne 5) “w m s g e fin tiv ela oi e de ia al av n ro r ra a en th ni es s tio re w of ce s . In m ac o t r e a r “v o r en a h m h f he lier m es ze b of n is it te s a g c e d ut Sc e in h n in re ch ay e ar lve e. F iso hr ren ay de uis ot ear as pa an is h ith c Sc th s su il , vo ur D op p m n ng in n ere ra d m izo er re hi an lee c n at d hiz ith his bee isti an h a wh m ne or p o as zo f p fe an Sc n w . T e d th wit s, et g e hr f S in p em a av to an s er a co e c g h n i o i h s tiv m nia hi re re it iat ren h ult ric al atio ap e z c u s oc oph litie iffic me ivid cin pe sy mon in s oph o u A d l ar mp in oc a d l m be ian in ha s to n i t n s m o o y A ha nd at s. t a te d s, on

attention. No single symptom is pathognomonic o and drive, and f ty, volition ough bizarre delusions are considered to be e Schizophrenia; the c capaci egarding its veracity. Alth specially ch diagn r hedoni pes of auditory hallucinations (i.e., two or eech, tory evidence cultural contexts. Certain ty more voices aracteristic of osis involve and gloves on a hot day), o nd sp Sc s c r m ay d is ght a ar contradic ience in certain multiple overcoats, scarves, pl ay clearly in onversing with hizophrenia the recog le f thou er ring her affective flattening is sufficiently persist vity o despite c ligious exp nner (e.g., wea h peers to determine whet ent to meet appropriate se one anoth , “bizarre nition of er xu re n a a ducti th ld wit nution or emptiness of affect. Fina lly f e e a mi , m e o ch di c l cr ro s r n b it ic o s er v e e nv ” n h o i on eracting iron a usual d pro renia have a ic m s part o f is h y an e belie normal s in an un the person int se with Schizoph child hood or adolescence, however, there may be a failure to a mental understim . Alogia (po vior (e.g., es main ay be d tellation s a enc v ta ch th p o s in t, flu which may be , may dre to observe t, whereas th turbance begin or concrete; and their behavior may be peculiar but not grossly dis ieve what would ulation or de erty of spe ublic ma ining a ifficult to of sign org is t ffec s r h e m l c h d s d s g, a tion wit ination shevele be usefu ainful affe toms. If the or overly abstrac sia. This symptom predisposes the individual to noncompliance with anized (e.g., m ave been ex oralizatio ch) is ma turbatio unning judge, and s i n) n um c c p p orin e, p y c n e tre y gno onit onvi Hallu rkedly d e. It ma intensely set of sym ssive, vagu , termed anoso 80% to 90% of individuals with Schizophrenia being regular cigarette s atment and ha bling to the ected for may resu ifested or unp ommen specia mptom mokers. the in by b s been mselv redi a lt in t n lly a al m of c der. on igre sa roke tim vidence of focal abnormalities, with medial te g from Fu le c ary e d r fo rt m p vior ree isor ear m of the rience a efore the able but d s seen in st mates rangin mporal lobe, there is e or al st ructures hermore, th und to be s, collec ividual r arned ief, lac table a on the cross ssoci ychotic medication, in indivi eha deg tic D app b st pe nd ficit tin es o a a (h r to treatment with antips a du ith esti n. Within the te p al de n, b the cho may d mo lly ex ieved ersta de and prio igh, w als with Schizophrenia. Perh als with Schizoph ippocampus e individu redictive g odd a ther tha pathy a nic, em nd unt perso differe ted w atio t on Psy rson inishe typica en ach rally und eurologicpecially h ted less ofte sychotic episo be more common among individu als te renia w , amy aps the mos rigg n’s nd a na nd of hi nt c ith e ho n g e a nic par her n ay tp s a pty e t d t g m n i eye contact, and body lang d m f p u d co n, i a p t ge io a v a h , e m w p r io hi t l e e o o ch m a o t e a s in v e o , r mu in a implic e ears) lit rep ere hou ultu mp n ss o ry e is e heir firs a d b g en s yd r a tional express om ends or any ne. Th clearl depres hich h ay be warene endenc al lobe is ls during t mations of th in styles of emo Disorganized speech is observed in a number of disorders across cultures. associated clinical re nd ento moke h relapse ently w rioratio ion. In lies. T d agit ghts res. aired rhina miss eavi physi atio or with child If the a De m p orth n in a e dc rate w ua nt lfor e s he nces common. i remains unclear. Evid c o e h ss ly b nc e re s l i ln l oc o e an dep nia ygi ss is s of hat il a o fr e De e fro et k of o divid ech m m tle ma differe a la r ge body of lite od onset (e.g sessment is l finding n, as we cortex) and tos, incre less o functiotablish ndivid n (e.g ehav usion cupa fines late-ons those of women. ge and phre ing h vene ptom elow t ir spe the lac Nicotin while th mong in s or sub sitivity to ions may be s b , ll ., rature d i o n t e thology de ua e n a . a n do emons Communi conducte are moto as in u as well choos ased n jects) ning. ing th ual w ., shoior) h s are tiona ng ake hiz tai ess sym rly b ); th ble to e high olume, found e-set ey quires se l hallucina iable brain pa personality traits th catio naff trates utin ave de l or d in r ab as t e cig um . In Co e p ith v id , la m f Sc ain xpr with lea ions re ra ntif ar t re isua izoid n e th a a n a t ing ult to tic o l or m nal e uals g is c cinat ompa rders sed in eficits a ow- or wof affec s, and v hether ide pal and sch S chizo Disorder langua ormali cted fi he sup aretteber of additi mpar resen logia g or bee eme soc nk rst ties ial on ing d s, P phre n ge er s s in c iso crea e d ec ent adult hizoty a narr e of w thi iffic ma ea otio vid nin allu i w e c b m w D s io v u b d n c , s e i o n s f d e t ia s y d o t d i d al ess the a m m nd ctio d h is ex ervasivethat is . Most egree r tem ith hi olunt to the the i of n ppea eari ons izar func nti es ymp ng of e at i fun orme . It ma elate to be ny of d palahe ass bserve ver, the ncidence d n e a n o id g pres r p r f a -R y d T ri we sed Develoifferent f thes relativ oral g h nic ry ho se po divid gativ s to g). C ere e if t tionin he ere tim s ari ge t th lly, eo inf me as ep an fac ica ce of rateg tance foun that m ly arc tation. n thos ure. Ho a highe ha pm diff es sit ua e fro e ar yr otin sp ar d t he g e t n t h a yp n , s o ed p r r r e s e n r e ntly ental Dm the e like . For t us an e co ital a ive-li l with symp ve a e sh o be y ar . Ch tio is er as or he nd th B). T bsen ing s Sub y bee ence ., hig prese ted th ical pic en hav ly he nt dm ke d in in is a p h id tl l .g ep ea sid h n u to d ou p e c ar ra m d a t t c e o m p n li v i o a e n s f o n e n a rders ividu o be se re lanu nt. C issio sym naffe ms t iminu ld b artic lea acte erc ld id co su , hi ent erio the a c ity w iste ng e lies ( f verb eIab s the c tives o a r nd r a o less nie rela e p he be ving ally res Crit e in han bid ons easi ma wo ), as i l’s pr elate sons m tem omo ns, p ptom cted hat a tion e tak ular ly im ristic me s d im d t lud gly not ly li sion re p e) ( forc er t mor st c incr l ano l form be mpa hile si re of en ly c pl s a o , so po rbid oo s, n is n r y b a . inc ron lso dai cca at a -car n or rath f co s mo e is sica gica may acco nia, w e T h org ry la sid me ral ity er g lin to tho no ha us m t f r b e f e s f p t y p o a l e a a h r o u w l e g a at n t o i m th a s ld s o up o s t r se erso itse tes be h , the r ph the l ation rmen ophr od nized gua effe f the , mo ith Asych tive s m e us ght to a acte ble tom m o p s i o s a o g a s s c iz ia a in a e a s s r n ns nd ou itie p o o l l R n a mi ffect lluc imp Sch ge behae, ca ts fro neur t con nxie soc ymp y be d in tha ply istic nd (C tio a sh tiv arm pt on, en nes n. ral re t n r at m o v r s ty i nc on d) ac d w sym cati unse e ill latio mpo zoph ome at a d ha itive with on ior ( e mu tre psy iste Dis al fu tom hel mak is re this of S ot u iteri i fu si ea g n h u n n h S se e.g st at ch nt or nc s a pf in fl c c n on ys elu h in an ing du an of t op te ch g. s t s a og me u r t l e m h d o y d g f o l d d e’s orm mile any or e of ion al p , the ith S rorin lture sion hat c rs of r m ., Att be ta ent logi fou ers tioni re p l in th cte iteri izo ers A) e t r n w ir cu elu g t be p k na a n r f e n w c k e h n a m e d o p t m a n h m a g n io en o e y s m or nc ta ne io s n is tion en to ith a l de d to as a , an rticu akin diag in d too ren nda ay ot we g in in p ma co , w ese ifes ge reg ual , or ross n, d estin mem b b e em bet min ies ing r ac ions pr man the by divid tion s ac ildre ugg ily tw Def ens nti p ficits be s lso d a larly g th nos ecre bro ia. I ble e c h s fam e d lt n e t b a e ee ici ur sy f in d n an ion um cu te th la th a e ine ll i in tyl n c e n 1 t/H e t ch are mall een poo com is d is o ase adl the and onc e ct a h iffi lat e o l re ing t is os am lly i ord e s p. I enc ong 8 a yp ha oti th er in rer m ete f Sc d f y. F se d ep e t c o i itiv stin ., o d e f th na ns igh n th ex ica co ativ rou vid am n m u n cr c on rm h lu o ty o tu d ra a gn di e.g g t tiv by rso se ins ha en on oor arr g o e se 25 ctiv logi ed ght volu eas ours in ina izop enc r ex pe not aliz co he t ( in ffec ed rpe g., or s t h hr , p n n age als tho ye ity a is ica to me ing e the tio hr y a am s o de ed of r. T cep ead h a rm nte (e. t po ther s. Wng c sion on i his e is an n e ar Di n tio ref . ly of t er r th s, so ot n le D re ill pro . E nia nd ple f ha rive ge e er , l it fo , i es a o es o fu ti a r h l p vior n w e in .g. nc s th s to roc am on aria is in . Th he nd rde rela s. M ct m ecre cognes dro duc , p pro , a llu g t c th r, S ted oto or as ni s. D ma ati erh du fe na ha rso y b g (e erie es rou se p icits ht tic v nos own e hi at te t r e ed ze e l on a c e pe a in xp gg e fu ef rig is ag n ar p k fo re o ab fu t d p an a s a s m tion l e su ang dif e d left/ ngu e di un nia r wo otyp ling no nda hal in S ers d r l pr m nc tua ce d re es s y li th ins re m ic uis rm me am ch ona es e o h a h en M tic ali n ic iz li ep iden or m of t ch lt b ake ma zop u cu m re i i o b tie ta v o v tm a s h e s i o be vem arr s t l fe olu p no d t enc s.” diff lt to esis Sc tw en ier ha atu e s gn e u n ith e t s ta re i d ic e w f g e s a n Dis . Be r ft m dif tho en 25 o be larly pa wom an r in e s of r

e.g.

studies

symptom

disorder

considered

include

features clinical criterion

findings individual

general un/common disorganized

Schizophrenia Language Dissection of the DSM-IV-TR

Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR Fourth Edition. American Psychiatric Publishing, Inc.; 4th edition (June 2000).


Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR Fourth Edition. American Psychiatric Publishing, Inc.; 4th edition (June 2000).


Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR Fourth Edition. American Psychiatric Publishing, Inc.; 4th edition (June 2000).


Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR Fourth Edition. American Psychiatric Publishing, Inc.; 4th edition (June 2000).

13 Language  

In progress: taking away common words.