We are pleased to present part 2 of a 2 part Delaware Journal Public Health issue on chronic disease. This issue contains articles on the Center of Biomedical Research Excellence in Cardiovascular Health (at the University of Delaware); a Community Perspective article on a Comprehensive Approach to Building Healthy Communities; CareLink in Action - Information Technology-enhanced Care Management Improves Clinical Outcomes and Lowers Costs in Chronic Disease and Episodes of Care; Understanding Type 2 Diabetes - Truth or Myth; A Public Health Response to Diabetes in Delaware through Partnership, Referral, and the Diabetes Self-Management Program; Strategies to Engage Community Partners in Research used by the Delaware Clinical and Translational Research, Accelerating Clinical and Translational Research; Preventing Chronic Disease - The Vision of the Delaware Division of Public Health; a Patient Guide to Prevent, Rest, and Treat Chronic Disease; and a Chronic Disease Lexicon of Terms.