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Contents Recently Released..............................................3 From the New Series: Imaging in Medical Diagnosis and Therapy ........................4 Nuclear Medicine Physics..................................7 Imaging ..........................................................10 Page 3

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Image Processing ............................................13 Medical Physics & Biomedical Engineering ....15 Sensors & Instrumentation..............................18 Related Books of Interest ................................20

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Visit us at to view more information and complete tables of contents for these and many other related books.

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MBMPHYS_5.5x8.5_MC_ISSUU:MBMPHYS MC_ISSUU 9/6/11 2:48 PM Page 3

Recently Released New!


Physics for Diagnostic Radiology

Handbook of Biomedical Optics

Third Edition

Edited by

Philip Palin Dendy

David A. Boas

Addenbrookes NHS Trust, Cambridge, UK

Harvard Medical School, Charlestown, Massachusetts, USA

Brian Heaton

Constantinos Pitris

Aberdeen Radiation Protection Services, UK

University of Cyprus, Nicosia

“… written in a clear and concise style, supported by excellent illustrations. The textbook describes recent state-of-the-art advances in medical imaging in a way radiologists, radiographers and medical physicists will find easy to understand. It is internationally recognised as one of the key textbooks in its field.”

Nimmi Ramanujam

—Dr. Keith Faulkner, North East Strategic Health Authority, UK

Fully revised and updated, this bestselling text helps readers understand how various imaging techniques work. This edition includes new chapters on PET and PACS as well as new material on digital receptors, radiation doses and risks to patients, and special radiographic techniques, including subtraction techniques and interventional radiology. It also emphasizes the differences between analogue and digital images and covers multi-slice CT and three-dimensional resolution, dual energy applications, and cone beam CT. Exercises, multiple choice questions, extensive references, and further reading aid in understanding.

Selected Contents: Fundamentals of Radiation Physics and Radioactivity. Production of X-Rays. Interaction of X-Rays and Gamma Rays with Matter. Radiation Measurement. The Image Receptor. The Radiological Image. Assessment of Image Quality and Optimisation. Tomographic Imaging with X-Rays. Special Radiographic Techniques. Diagnostic Imaging with Radioactive Materials. Positron Emission Tomographic Imaging. Radiobiology and Generic Radiation Risks. Radiation Doses and Risks to Patients. Practical Radiation Protection and Legislation. Diagnostic Ultrasound. Magnetic Resonance Imaging. Digital Image Storage and Handling. Multiple Choice Questions. Index. Catalog no. 83155, August 2011, 720 pp. ISBN: 978-1-4200-8315-6, $79.95 / £49.99 Also available as an eBook

Duke University, Durham, North Carolina, USA

Taking a broad yet detailed approach, this comprehensive handbook covers light-based diagnostic methodologies and light-mediated therapeutics as well as concepts and cutting-edge optical methods used in research and practice. Extensively illustrated, the book presents the theory and fundamentals, along with state-ofthe-art applications. The expert contributors also discuss advantages and disadvantages of various techniques. After introducing the background principles of optics, light sources, and irradiation and basic tissue optics concepts, the book focuses on spectroscopic methods, tomographic imaging, microscopic imaging methods, molecular probe development, and phototherapy. • Provides an in-depth introduction to the field, exploring applications for biomedical research, diagnosis, and therapy • Includes the theory and fundamentals of each subject with the aim of accessibility to a wide, multidisciplinary readership • Discusses advantages and drawbacks of various state-of-the-art techniques • Introduces the principles of optics, lights sources, and irradiation, as well as basic concepts in tissue optics • Covers spectroscopic methods, including tomographic imaging, microscopic imaging methods, molecular probe development, and phototherapy

Selected Contents: Background. Spectroscopy and Spectral Imaging. Tomographic Imaging. Microscopic Imaging. Molecular Probe Development. Phototherapy. Catalog no. 90364, June 2011, 831 pp. ISBN: 978-1-4200-9036-9, $149.95 / £95.00 Also available as an eBook

For more information and complete contents, visit


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From the New Series: Imaging in Medical Diagnosis and Therapy New!


Quantitative MRI in Cancer

Informatics in Medical Imaging

Edited by

Thomas E. Yankeelov, David R. Pickens, and Ronald R. Price

Edited by

Vanderbilt University, Nashville, Tennessee, USA

Steve G. Langer

Propelling quantitative MRI techniques from bench to bedside, this volume explains the biophysics and theory behind many MRI techniques and gives example of how these techniques are applied in cancer diagnosis and treatment. The first section of the book presents basic cancer biology, theoretical aspects of NMR/MRI physics, and the hardware required to form MR images. The next three sections cover image processing and characterizing tissue properties using endogenous and exogenous contrast mechanisms. The book concludes with emerging areas of MR cancer characterization. Leading the way toward more personalized medicine, this text brings together existing and emerging quantitative MRI techniques for assessing cancer. It provides a self-contained overview of the theoretical and experimental essentials and state of the art in cancer MRI. • Shows how MRI is used today for the diagnosis and therapy monitoring of cancer • Discusses qualitative and quantitative aspects of the techniques • Presents a detailed treatment of the state of the art in tissue characterization using endogenous and exogenous contrast agents • Covers image processing in cancer • Explores emerging trends in MR characterization, such as radiation therapy planning, molecular and cellular imaging, pH imaging, and hyperpolarized MR

Selected Contents: Physical Basis of Magnetic Resonance Imaging. Characterizing Tissue Properties with Endogenous Contrast Mechanisms. Characterizing Tissue Properties with Exogenous Contrast Agents. Image Processing in Cancer. Emerging Trends. Index. Catalog no. K11087, September 2011, 338 pp. ISBN: 978-1-4398-2057-5, $129.95 / £82.00 Also available as an eBook


George C. Kagadis University of Patras, Rion, Greece Mayo Clinic, Rochester, Minnesota, USA

This book presents a comprehensive survey of the field of medical imaging informatics. It reflects the considerable advances made in recent years, most notably in radiology. In addition to radiology, the book addresses other specialties, such as pathology, cardiology, dermatology, and surgery, which have now adopted the use of digital images. The text discusses basic imaging informatics protocols, picture archiving and communication systems, and the electronic medical record. It also details key instrumentation and data mining technologies used in medical imaging informatics as well as practical operational issues, such as procurement, maintenance, teleradiology, and ethics. • Introduces the basic ideas of imaging informatics, the terms used, and how data are represented and transmitted • Emphasizes the fundamental communication paradigms: HL7, DICOM, and IHE • Describes information systems that are typically used within imaging departments: orders and result systems, acquisition systems, reporting systems, archives, and information-display systems • Outlines the principal components of modern computing, networks, and storage systems • Covers the technology and principles of display and acquisition detectors, along with other key computer technologies • Discusses procurement and maintenance issues, ethics and its relationship to government initiatives such as HIPAA, and constructs beyond radiology

Selected Contents: Introduction to Informatics in Healthcare. Standard Protocols in Imaging Informatics. Information Systems in Healthcare Informatics. Key Technologies. Operational Issues. Medical Informatics beyond the Radiology Department. Catalog no. K11526, October 2011, c. 363 pp. ISBN: 978-1-4398-3124-3, $149.95 / £95.00 Also available as an eBook

New & Essential Medical Physics Books from CRC Press

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From the New Series: Imaging in Medical Diagnosis and Therapy Coming soon!

Coming soon!

Adaptive Motion Compensation in Radiotherapy

Image-Guided Radiation Therapy

Edited by

J. Daniel Bourland

Martin Murphy

Wake Forest University, Winston-Salem, North Carolina, USA

Virginia Commonwealth University, Richmond, USA

Reflecting recent advances in the field, this book provides the first detailed treatment of online interventional techniques for motion compensation radiotherapy. It explains how adaptive motion intervention is imaging-intensive and relies on near real-time image acquisition and processing. With a focus on the strategy of online motion compensation, the book discusses necessary motion detection methodology, repositioning methodology, and how to interpret and respond to target movement data in real time. It covers methods of detection and correction and then offers examples. It also gives attention to the distinct problems in dose planning and delivery posed by each adaptation technology.

Edited by

Image-guided radiation treatment (IGRT) is rapidly becoming the standard approach to external-beam radiation therapy. Its advantages include greater precision, reduced likelihood of positioning errors, and online correction of motion errors. This volume provides a cutting-edge overview of the latest IGRT technology and systems, including a historical perspective, discussion of future directions, and firsthand insights from experienced expert authors. Each chapter discusses the geometry of the imaging and treatment system, relevant imaging principles and algorithms, treatment principles, image fidelity (scatter, spatial, and contrast resolution), and clinical applications.

• Explains problems with dose planning and delivery of various methods

• Presents contributions from an international team of experts • Discusses the geometry of the relevant imaging system • Presents imaging principles and algorithms for each modality • Gives detailed information about image fidelity, including the spatial and contrast resolution • Includes clinical applications

• Discusses fault detection and quality assurance

Selected Contents:

Selected Contents:

Introduction. 3D Conformal Radiation Treatment (3D CRT). Intensity Modulated Radiation. Optical/Remote Monitoring IGRT. Ultrasound IGRT. MV Fan-Beam IGRT Rock Mackie (Tomotherapy®). CT In-Room IGRT. kV Cone-Beam IGRT (Elekta®) . kV Cone-Beam IGRT (Varian®). MY Cone-Beam IGRT (Siemens®). kV Fluoroscopic + IMRT IGRT (BrainLab®). kV Fluoroscopic + Robotic Linac IGRT (Cyberknife®). Multi-Modality Image Registration. Shape and Deformable Models. Future Directions.

• Provides an overview of the full spectrum of image guidance techniques for medical interventions in the context of the critical issues of motion compensation • Covers adaptive motion compensation • Pays special attention to the interplay between beam and target movement

OVERVIEW: Introduction to Motion Adaptation in Radiotherapy. Online Target Localization. Control Loops and Timing. BEAM GATING AND BEAM TARGET REALIGNMENT: Robotic Linac Tracking. MLC Adaptation. Charged Particle Beam Steering. Couch Realignment. INTEGRATED SYSTEMS: CyberKnife. ViewRay. MRI and Linac. TREATMENT PLANNING, QUALITY ASSURANCE, AND FAULT DETECTION: Treatment Planning. Optimization. Online Fault Detection and Response. Quality Assurance. Catalog no. K11160, December 2011, c. 168 pp. ISBN: 978-1-4398-2193-0, $149.95 / £95.00 Also available as an eBook

Catalog no. K10143, February 2012, c. 264 pp. ISBN: 978-1-4398-0273-1, $129.95 / £82.00 Also available as an eBook

For more information and complete contents, visit


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From the New Series: Imaging in Medical Diagnosis and Therapy Quality and Safety in Radiotherapy Edited by

Adaptive Radiation Therapy

Todd Pawlicki, Peter Dunscombe, Arno J. Mundt, and Pierre Scalliet

Edited by

“The contents and layout are excellent.”

“The breadth of the book is impressive, and the authors of each chapter provide a wealth of up-todate references, making it easy for readers who are interested in exploring certain ART techniques and technologies in more detail … a valuable work on a very dynamic field …”

—Eric E. Klein, Washington University School of Medicine

“… well written and easy to read. Because of its comprehensive nature, students as well as seasoned radiation therapy professionals will find this book useful. … No one book contains the range of topics covered in this book. … Each chapter includes a wealth of references which readers can use to supplement the material in this book. This is an important reference on critically important topics.” —Arthur Olch, FAAPM, Children’s Hospital Los Angeles

This work encompasses not only traditional technically oriented quality assurance activities, but also general approaches regarding quality and safety. Experts both inside and outside the field discuss the processes and the people delivering the service. The book discusses lean thinking; looks at reactive and prospective error management techniques; deals broadly with techniques to monitor, assure, and improve quality; and provides explicit details of quality control relating to equipment and patient-specific issues. • Presents a global view of modern quality techniques that encourage improved patient care and safety • Includes examples that highlight the use of techniques from manufacturing and engineering • Offers guidelines for setting up quality assurance programs and performing quality assurance procedures

Selected Contents: Introduction to Quality Assurance and Quality Management. Medical Quality Assurance in Radiotherapy. Quality of Systems and Processes in Radiotherapy. Patient-Specific Quality Assurance in Radiotherapy. Catalog no. K10241, December 2010, 643 pp. ISBN: 978-1-4398-0436-0, $129.95 / £82.00 Also available as an eBook


X. Allen Li Medical College of Wisconsin, Milwaukee, USA

—Moyed Miften, Medical Physics

“The editor and authors are to be commended for putting together this excellent book describing the rationale, technologies, implementation, and future research for adaptive radiation therapy (ART). … The book contains a wealth of useful information ranging from practical workflow issues to directions of future research. I recommend this book for medical physicists and radiation oncologists who are interested in clinical practice and research utilizing advanced imaging and radiation therapy technology.” —James C.H. Chu, Rush University Medical Center

This comprehensive book explores ways to optimize radiation plans. This includes the use of patient-specific 3D and 4D morphological and biological information to help define targets and individualize post-treatment assessment. Worldclass experts discuss technologies for the delivery of treatments across various modalities and review clinical examples that demonstrate modern applications of ART for various cancers, such as brain tumors, sarcomas, and lung, prostate, and breast cancer.

Selected Contents: Treatment Planning and Delivery of Physically and Biologically Adaptive Radiation: An Introduction. Part I: Treatment Planning. Part II: Treatment Delivery. Part III: Clinical Applications. Catalog no. K10840, January 2011, 427 pp. ISBN: 978-1-4398-1634-9, $149.95 / £95.00 Also available as an eBook

New & Essential Medical Physics Books from CRC Press

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Nuclear Medicine Physics Measurement and Detection of Radiation Third Edition

Nuclear Medicine Physics

Nicholas Tsoulfanidis

Edited by

University of Nevada, Reno, USA

Sheldon Landsberger University of Texas, Austin, USA

“This book is an excellent review of nuclear detection systems. The updated text is particularly timely with regard to the current zeitgeist for homeland security, nuclear non-proliferation, and nuclear security.” —Steven Biegalski, University of Texas

With the miniaturization of equipment, increased speed of electronic components, and more sophisticated software, radiation detection systems are now more productively used in many disciplines. Continuing in the tradition of its bestselling predecessors, this edition illustrates the fundamentals of nuclear interactions and radiation detection with a multitude of examples and problems. It offers a clearly written, accessible introduction to nuclear instrumentation concepts.

New to the Third Edition • A new chapter on the latest applications of radiation detection, covering nuclear medicine, dosimetry, health physics, nonproliferation, and homeland security • Updates to all chapters and subtopics within chapters, as needed • Many new references and a completely updated bibliography

Selected Contents:

Joao Jose De Lima IBILI Biophysics Institute, Coimbra, Portugal

“… The data contained here will no doubt prove vital to researchers in multiple looking for ways to expand and upgrade patient care (specifically, oncologists charged with diagnosing and treating various forms of cancer will immediately benefit from learning how nuclear imaging techniques can enhance the patient experience in the clinical setting).” —The Electric Review, January 2011

Nuclear Medicine Physics offers a state-of-theart account of the physics behind the theoretical foundation and applications of nuclear medicine. It covers important physical aspects of the methods and instruments involved in modern nuclear medicine, along with related biological topics. The book discusses the production of radioisotopes and radiopharmaceuticals, positron physics and positron applications in medicine and biology, and modern radiation detectors and measuring methods. It also explores systems in nuclear medicine, imaging methodologies, dosimetry, and the biological effects of radiation. • Discusses topics useful in nuclear medicine R&D and clinical applications • Contains material on subjects not frequently covered in similar books, such as accelerators and positron physics

Introduction to Radiation Measurements. Statistical Errors of Radiation Counting. Review of Atomic and Nuclear Physics. Energy Loss and Penetration of Radiation through Matter. GasFilled Detectors. Scintillation Detectors. Semiconductor Detectors. Relative and Absolute Measurements. Introduction to Spectroscopy. Electronics. Data Analysis Methods. Photon (Gamma-Ray and X-Ray) Spectroscopy. Charged-Particle Spectroscopy. Neutron Detection and Spectroscopy. Activation Analysis. Health Physics Fundamentals. Applications of Radiation Detection. Appendices. Index.

• Describes the production of radioisotopes and the biological effects of radiation

Catalog no. 91859, December 2010, 518 pp. ISBN: 978-1-4200-9185-4, $129.95 / £82.00 Also available as an eBook

Catalog no. C7958, November 2010, 524 pp. ISBN: 978-1-58488-795-9, $149.95 / £95.00 Also available as an eBook

• Presents novel physical approaches relating to radiopharmaceuticals and their use

Selected Contents: Introduction. Radioisotopes and Radiopharmaceuticals Production. Positron Physics: Applications in Medicine and Biology. Modern Radiation Detectors and Measuring Methods. Systems in Nuclear Medicine. Imaging Methodologies. Dosimetry and Biological Effects of Radiation. Index.

For more information and complete contents, visit


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Nuclear Medicine Physics

Edited by

Semiconductor Radiation Detection Systems

Harald Paganetti

Edited by

Massachusetts General Hospital and Harvard Medical School, Boston, USA

Krzysztof Iniewski

Coming soon!

Proton Therapy Physics

Compared to x-ray-based radiotherapeutic modalities, proton therapy provides greater 3D localization, higher beam doses, access to deeper tumors, and less damage to surrounding healthy tissue. Though over fifty years old, it is now coming to the forefront of cancer treatment with a greater understanding of the biophysics and better treatment and patient outcomes. This book presents an overview of proton therapy that addresses all key topics, including, biophysics, accelerators, hardware, beam delivery, treatment planning, dose calculation, quality assurance, and precision. • Provides an overview of proton therapy • Covers beam delivery using passive scattering and magnetic beam scanning • Details the physics of treatment planning for homogenous fields and intensity-modulated fields • Discusses precision and uncertainties for both moving and non-moving targets

Selected Contents: Introduction. History and Rationale for Proton Therapy. Physics of Protons Stopping in Matter. Proton Accelerators, Transport and Gantries. Beam Delivery Using Passive Scattering. Beam Delivery Using Magnetic Beam Scanning. Characteristics of Clinical Proton Beams. Physics of Treatment Planning for Homogeneous Fields. Physics of Treatment Planning for IntensityModulated Fields. Dose Calculation Algorithms. Quality Assurance and Dosimetry. In Vivo Dose Verification. Precision and Uncertainties for Non-Moving Targets. Precision and Uncertainties for Moving Targets. Secondary Radiation. Shielding. The Physics of Proton Biology. Catalog no. K11646, December 2011, c. 696 pp. ISBN: 978-1-4398-3644-6, $129.95 / £82.00 Also available as an eBook

CMOS Emerging Technologies Inc. Vancouver, British Columbia, Canada

This essential resource addresses the state of the art in the design of semiconductor detectors and integrated circuits in the context of medical imaging using ionizing radiation. It includes exciting opportunities in x-ray detection, CT, bone dosimetry, and nuclear medicine applications, such as PET and SPECT. In addition to medical imaging, the book explores other applications of semiconductor radiation detection systems in areas related to security, such as luggage scanning, dirty bomb detection, and border control. • Addresses semi-conductor detector and integrated circuit design • Describes new advances in x-ray detection, CT, bone dosimetry, and nuclear medicine • Explores semiconductor radiation detection systems in security applications

Selected Contents: Spatial and Spectral Resolution of Semiconductor Detectors in Medical Imaging. Silicon Radiation Detectors with ThreeDimensional Electrodes (3D Detectors). Cadmium Zinc Telluride Pixel Detectors for Hard X-Ray Astrophysics. Hydrogenated Amorphous Silicon Radiation Detectors. Novel X- and Gamma-Ray Detectors Based on Metamaterials. Multicell Geiger-Mode Avalanche Photodiodes: Silicon Photomultipliers. Hybrid Photodetectors for Single-Photon Detection. High-Resolution CdTe Detectors and Application to Gamma-Ray Imaging. Caliste: Microcamera for Hard X-Ray Astronomy. Hybrid Pixel Array Detectors for Photon Science. XPAD, a Photon-Counting Imager for X-Ray Applications. Ultrafast Electron Beam Tomography. Compton Imaging: Principles and Practice. Multimodality Imaging with MR/PET and MR/SPECT. Hard X-Ray Imaging Detectors Onboard the BalloonBorne High-Energy Focusing Telescope. Index. Catalog no. K10214, May 2010, 400 pp. ISBN: 978-1-4398-0385-1, $149.95 / £95.00 Also available as an eBook


New & Essential Medical Physics Books from CRC Press

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Nuclear Medicine Physics



Essentials of Functional MRI

Introduction to Drug Evaluation and Dose Estimation

Patrick W. Stroman

Lawerence E. Williams

Queen’s University, Kingston, Ontario, Canada

City of Hope National Medical Center, Duarte, California, USA

“A comprehensive book, combining a strong theoretical background with profound practical hints for the use of fMRI in medical research … represents a major step forward.”

“I believe that it will be very valuable in our education of Ph.D. students and also very valuable for researchers in this area. I will recommend the book to my colleagues.”

—Massimo Filippi, Scientific Institute HSR, Italy

—Sven-Erik Strand, University of Lund

“I find the book packed with information. It will be useful for both a clinical audience and MR technologists.”

“The book is written in a very clear style, and is accessible not only to physicists, but to any professional involved in radiopharmaceutical development and clinical or preclinical experiments. … an essential part of my library.”

—W. Einar Mencl, Haskins Laboratories and Yale University

With a minimum of technical jargon and advanced mathematics, this book presents a solid, practical foundation on fMRI as a tool for research and practice. The author reviews research and clinical applications for disease diagnosis, treatment monitoring, and surgical planning. He also covers the underlying biophysical mechanisms that relate MRI changes to neuronal activity as well as the expanded use of fMRI beyond the brain to the brainstem and spinal cord. • Provides a full-color interior with more than 130 figures • Explains how to design and analyze an fMRI study • Presents an overview of alternative fMRI methods • Discusses fMRI of the cortex, brainstem, and spinal cord

Selected Contents: Introduction. Basic Concepts. Source of the MR Signal and Its Properties. The Fundamental Building Blocks of MR Imaging Methods: Spin-Echoes and Gradient-Echoes. Creating an Image from the MR Signal. Principles and Practice of fMRI. fMRI Study Design. fMRI Data Analysis. Clinical Applications of fMRI. Supplementary MRI Methods. Glossary. Appendices. Catalog no. K10992, June 2011, 311 pp. Soft Cover, ISBN: 978-1-4398-1878-7 $79.95 / £49.99 Also available as an eBook

—Manuel Bardies, INSERM

Catalog no. K10532, December 2010, 326 pp. ISBN: 978-1-4398-1067-5, $129.95 / £82.00 Also available as an eBook

Coming soon!

Compound Semiconductor Radiation Detectors Alan Owens European Space Agency, Noordwijk, The Netherlands

This book describes all aspects of radiation detection and measurement that use compound semiconductors, including crystal growth, detector fabrication, and spectroscopic performance. A comprehensive reference source for researchers in various disciplines as well as graduate students in specialized courses, the text outlines the potential and limitations of semiconductor detectors. The author covers growth techniques, detector fabrication, contacting systems, current radiation detection systems, and performance improvements. Catalog no. K13387, December 2011, c. 570 pp. ISBN: 978-1-4398-7312-0, $129.95 / £82.00 Also available as an eBook

For more information and complete contents, visit


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Imaging New!

Lung Imaging and Computer Aided Diagnosis Edited by

Ayman El-Baz University of Louisville, Kentucky, USA

Jasjit S. Suri Biomedical Technologies, Inc., USA

Lung cancer remains the leading cause of cancerrelated deaths worldwide. Early diagnosis can improve the effectiveness of treatment and increase a patient’s chances of survival. Thus, there is an urgent need for new technology to diagnose small, malignant lung nodules early as well as large nodules located away from large diameter airways because the current technologies—namely, needle biopsy and bronchoscopy—fail to diagnose those cases. However, the analysis of small, indeterminate lung masses is fraught with many technical difficulties. Often patients must be followed for years with serial CT scans in order to establish a diagnosis, but interscan variability, slice selection artifacts, differences in degree of inspiration, and scan angles can make comparing serial scans unreliable. Lung Imaging and Computer Aided Diagnosis brings together researchers in pulmonary image analysis who present state-of-the-art image processing techniques for detecting and diagnosing lung cancer at an early stage. The book addresses variables and discrepancies in scans and proposes ways of evaluating small lung masses more consistently to allow for more accurate measurement of growth rates and analysis of shape and appearance of the detected lung nodules. Dealing with all aspects of image analysis of the data, the book examines: • Lung segmentation • Nodule segmentation • Vessels segmentation • Airways segmentation • Lung registration • Detection of lung nodules • Diagnosis of detected lung nodules • Shape and appearance analysis of lung nodules Contributors also explore the effective use of these methodologies for diagnosis and therapy in clinical applications. Arguably the first book of its kind to address and evaluate image-based diagnostic approaches for the early diagnosis of lung cancer, Lung Imaging and Computer Aided Diagnosis constitutes a valuable resource for biomedical engineers, researchers, and clinicians in lung disease imaging.


Selected Contents: A Novel Three-Dimensional Framework for Automatic Lung Segmentation from Low- Dose Computed Tomography Images. Incremental Engineering of Lung Segmentation Systems. 3D MGRF-Based Appearance Modeling for Robust Segmentation of Pulmonary Nodules in 3D LDCT Chest Images. Ground-Glass Nodule Characterization in High-Resolution Computed Tomography Scans. Four-Dimensional Computed Tomography Lung Registration Methods. Pulmonary Kinematics via Registration of Serial Lung Images. Acquisition and Automated Analysis of Normal and Pathological Lungs in Small Animals Using Computed Microtomography. Airway Segmentation and Analysis from Computed Tomography. Pulmonary Vessel Segmentation for Multislice CT Data: Methods and Applications. A Novel Level Set-Based Computer-Aided Detection System for Automatic Detection of Lung Nodules in Low-Dose Chest Computed Tomography Scans. Model-Based Methods for Detection of Pulmonary Nodules. Concept and Practice of Genetic Algorithm Template Matching and Higher Order Local Autocorrelation Schemes in Automated Detection of Lung Nodules. Computer-Aided Detection of Lung Nodules in Chest Radiographs and Thoracic CT. Lung Nodule and Tumor Detection and Segmentation. Texture Classification in Pulmonary CT. Computer-Aided Assessment and Stenting of Tracheal Stenosis. Appearance Analysis for the Early Assessment of Detected Lung Nodules. ... Catalog no. K12032, August 2011, 496 pp. ISBN: 978-1-4398-4557-8, $189.95 / £114.00 Also available as an eBook

New & Essential Medical Physics Books from CRC Press

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Diffuse Optical Tomography Principles and Applications Huabei Jiang University of Florida, Gainesville, USA

DOT can provide spatial distributions of intrinsic tissue optical properties or molecular contrast agents through model-based reconstruction algorithms. This book covers almost every aspect of DOT, from mathematics, reconstruction algorithms, instrumentation, and phantom experiments to clinical applications. It presents the fundamental principles of DOT, including its mathematical foundations and computational methods, and explains how to set up experimental image systems and how to translate laboratory studies into clinical applications. Catalog no. K12111, December 2010, 375 pp. ISBN: 978-1-4398-4757-2, $129.95 / £82.00 Also available as an eBook

Essentials of Forensic Imaging A Text-Atlas Angela D. Levy Georgetown University Hospital, Washington, D.C., and Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA

H. Theodore Harcke, Jr. Armed Forces Institute of Pathology, Washington, D.C., and Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA

“The work is very well done and makes a significant contribution to the literature on the topic … The printing and illustration quality is outstanding.” —Joel Lichtenstein, University of Washington

“… well illustrated through correlation of photographs and radiological images of the highest quality. … The book is certain to find extended use in training programs and daily death investigation and documentation.” —William A. Murphy, Jr., University of Texas MD Anderson Cancer Center

“… useful for practicing forensic pathologists. The numerous examples covering a wide variety of forensic cases … illustrate the value of imaging techniques in medicolegal death investigation.”

PACS and Digital Medicine Essential Principles and Modern Practice Yu Liu St. Luke’s Medical Center, Milwaukee, Wisconsin, USA

Jihong Wang University of Texas MD Anderson Cancer Center, Houston, USA

“… a thorough and practical reference for radiologists, administrators, engineers, and others who might create, manage, or use such a system. …” —SciTech Book News, February 2011

This useful guide explains how PACS are used in radiology, teleradiology, cardiology, pathology, and radiation oncology. The authors cover PACS system components, quality control, IT infrastructures, networks, and data storage technologies. They also describe industry standards; security, privacy, and safety regulations; and the replacement of legacy systems. Catalog no. C8365, November 2010, 367 pp. ISBN: 978-1-4200-8365-1, $129.95 / £82.00 Also available as an eBook

—John Butts, University of North Carolina at Chapel Hill

This volume provides a technical and interpretive foundation for applying modern cross-sectional imaging to forensic autopsy. It integrates more than 300 color images with basic forensic pathology in a topical format. After introducing basic concepts and imaging techniques, chapters are organized by cause of death. The atlaslike presentation is supported by full text explanations that review relevant forensic and radiologic principles.

Selected Contents: Introduction to Forensic Imaging. Integrating Imaging and Autopsy. Postmortem Change and Decomposition. Gunshot Wounds. Blunt Force Injury. Death from Fire and Burns. Blast Injury. Sharp Force Injury. Death by Drowning and Bodies Found in Water. Suicide. Natural Death. Other Causes of Death. Beyond Standard Autopsy. Catalog no. 91115, December 2010, 282 pp. ISBN: 978-1-4200-9111-3, $149.95 / £95.00 Also available as an eBook

For more information and complete contents, visit


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Imaging Handbook of Physics in Medicine and Biology Edited by

Handbook of Photonics for Biomedical Science

Robert Splinter

Edited by

University of North Carolina at Charlotte, USA

Valery V. Tuchin

“The handbook includes hundreds of diagrams, images and tables, making it a useful tool for both medical physicists/engineers and other medical/biology specialists … includes materials that are rarely combined together, which strengthens its interdisciplinary approach.”

Addressing problems in biomedical optics and biophotonics, this handbook describes advanced biophotonics methods and techniques intensively developed in recent years. It discusses optical and terahertz spectroscopy and imaging methods for biomedical diagnostics based on the interaction of coherent, polarized, and acoustically modulated radiation with tissues and cells. The book covers modalities of nonlinear spectroscopic microscopies, photonic technologies for therapy and surgery, and nanoparticle photonic technologies for cancer treatment and UV radiation protection. The text also elucidates the advanced spectroscopy and imaging of normal and pathological tissues.

—Physics in Medicine and Biology, 55 (2010)

“… an excellent work by a highly competent team. The book chapters follow logically from the properties of the cell membrane through sensors and electroreception, biomechanics and fluid dynamics to the recording of bioelectrical signals, bioelectric impedence analysis, x-ray and computed tomography, magnetic resonance imaging, nuclear medicine, ultrasonic and thermographic imaging … keep this book close at hand and do not hesitate to use it frequently.” —BioMedical Engineering OnLine, 2010

This volume covers materials associated with replacement or repair of tissues or entire tissue structures. It describes specific biological features and then delves into the physics of explicit anatomical structures starting with the cell. The contents are then organized by organ type and biological function. In addition to physical descriptions, each chapter discusses principles of related diagnostic methods and technological aspects of therapeutic applications. A final section on regenerative engineering emphasizes biochemical and physiochemical factors important in improving or replacing biological functions.

Selected Contents: Anatomical Physics. Physics of Perception. Biomechanics. Electrical Physics. Diagnostic Physics. Physics of Accessory Medicine. Physics of Bioengineering. Catalog no. 75241, April 2010, 548 pp. ISBN: 978-1-4200-7524-3, $149.95 / £95.00 Also available as an eBook


Saratov State University, Russia

• Describes important methods, such as finite-difference time-domain simulation, for the mathematical modeling of light transport and interaction with cells • Discusses recent optical and terahertz spectroscopy and imaging methods for biomedical diagnostics • Presents novel modalities of photon ballistic, multidimensional fluorescence, Raman, confocal, CARS, and other nonlinear spectroscopies that provide molecular-level cell and tissue imaging • Explores key photonic technologies for therapy and surgery, including photodynamic, low-intensity laser, and photothermal therapies • Explains how nanoparticle photonic technologies are used for cancer treatment and human organism protection from UV radiation • Focuses on advanced spectroscopy and imaging of a variety of normal and pathological tissues, such as embryonic, eye, skin, brain, and gastric tissues Catalog no. K10313, May 2010, 868 pp. ISBN: 978-1-4398-0628-9, $149.95 / £95.00 Also available as an eBook

New & Essential Medical Physics Books from CRC Press

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Image Processing New!

Applied Medical Image Processing A Basic Course Wolfgang Birkfellner Medical University of Vienna, Austria

“[A]n outstanding work that will be of interest to virtually all biomedical engineers. … In each wellorganized chapter, important concepts and definitions are described concisely and well. Relevant medical images used for processing compliment many of the concepts discussed. Where important, the mathematical formulation is provided. The text and images refer to several MATLAB-based programming examples that are provided at the end of each chapter. … an excellent reference work for biomedical engineers, scientists, and clinicians. …” —Edward J. Ciaccio, Columbia University, BioMedical Engineering OnLine, 2011

“The plethora of examples in each chapter … allows the reader to apply the theory and visually assess the outcomes. This book is a perfect blend of theory and practice. I highly recommend it.” —Pascal Fallavollita, Technische Universität München

Using real medical images and techniques, this book provides a practical introduction to medical image processing. The author combines clearly written textual explanations with numerous tables, diagrams, and figures as well as illustrative examples and exercises using MATLAB® and Octave. The accompanying CD-ROM contains sample images and files that can be used with either program.

Selected Contents: A Few Basics of Medical Image Sources. Image Representation. Operations in Intensity Space. Segmentation. Filtering and Transformations. Spatial Transforms. Rendering, Visualization, and Surface Models. Registration. Volume Reconstruction. Appendix. Glossary. Index. Catalog no. K11176, September 2010, 403 pp. ISBN: 978-1-4398-2444-3, $69.95 / £44.99 Also available as an eBook

Practical Biomedical Signal Analysis Using MATLAB® Katarzyn J. Blinowska and Jaroslaw Zygierewicz University of Warsaw, Poland

This book not only covers the current techniques of biomedical signal processing, but it also offers hands-on guidance on which methods are appropriate for a given task and different types of data. The first several chapters of the text describe signal analysis techniques—including the newest and most advanced methods—in an easy and accessible way. MATLAB® routines are listed when available and freely available software is discussed where appropriate. The final chapter explores the application of the methods to a broad range of biomedical signals, highlighting problems encountered in practice. • Provides hands-on guidance for those working in the area of biomedical signal analysis • Covers tools for stationary and nonstationary signals, nonlinear methods of signal analysis, and models and measures for multivariate signals • Compares the advantages and disadvantages of different methods in the context of applications • Refers to MATLAB routines and freely available software found on the Internet • Applies the methods to a variety of signals: o electric: electroencephalogram, electrocorticogram, event-related potential, electrocardiogram, heart rate variability signal, electromiograms, electroenterograms, and electrogastrograms o magnetic: magnetoencephalogram and magnetocardiogram o acoustic: phonocardiograms and otoacoustic emissions

Selected Contents: Introductory Concepts. Single Channel (Univariate) Signal. Multiple Channels (Multivariate) Signals. Application to Biomedical Signals. References. Index. Catalog no. K10605, September 2011, 324 pp. ISBN: 978-1-4398-1202-0, $99.95 / £63.99 Also available as an eBook

For more information and complete contents, visit


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Image Processing


Introduction to Holography Vincent Toal Dublin Institute of Technology, Ireland

“The breadth of coverage of this book is remarkable …” —Joseph W. Goodman, Stanford University

“The structure and approach of the book are excellent. … a great inspiration for any researcher in the area of signal processing.” —Joseph Rosen, Ben Gurion University of the Negev

“This is a complete treatise on holography… I thoroughly recommend it to both students and experienced practitioners of the subject.” —Chris Dainty, National University of Ireland

“… essential reading for those involved with photonics, a primary reference worth purchasing.” —Martin Richardson, DeMontfort University

With more than 300 illustrations, this practical guide explains how to use holographic techniques to solve specific problems in a variety of fields. It covers numerous existing and emerging holographic applications in advertising, data storage, life sciences, and nanoengineering. The text chronicles the historical development of holography, reviews essential optics, presents basic holographic principles, and describes the conditions for successful holography in the laboratory.

Selected Contents: OPTICS: Light, Waves, and Rays. Physical Optics. PRINCIPLES OF HOLOGRAPHY: Introducing Holography. Volume Holography. HOLOGRAPHY IN PRACTICE: Requirements for Holography. Recording Materials. Recording Materials in Practice. APPLICATIONS: Holographic Displays. Other Imaging Applications. Holographic Interferometry. Holographic Optical Elements. Holographic Data Storage and Information Processing. Digital Holography. Computer-Generated Holograms. Holography and the Behavior of Light. Polarization Holography. Holographics Sensors and Indicators. Appendices. Catalog no. K10987, September 2011, 502 pp. ISBN: 978-1-4398-1868-8, $99.95 / £63.99


Signal Processing in Magnetic Resonance Spectroscopy with Biomedical Applications Dzevad Belkic and Karen Belkic Karolinska Institute, Stockholm, Sweden

Addressing the critical need in clinical oncology for robust and stable signal processing in MRS, this book explores cutting-edge theory-based innovations for obtaining reliable quantitative information from MR signals for cancer diagnostics. By defining the natural framework of signal processing using the well-established theory of quantum physics, it illustrates how advances in signal processing can optimize MRS. The book bridges the gap between mathematical signal processing methods and their clinical relevance in MRS, showing how accurate quantification helps in timely cancer detection. Applying the fast Padé transform (FPT) to several problems in oncology diagnostics, including ovarian, breast, and prostate cancer, the authors examine the remarkable ability of the FPT to unambiguously quantify isolated, tightly overlapped, and nearly confluent resonances.

Selected Contents: Basic Tasks of Signal Processing in Spectroscopy. The Role of Quantum Mechanics in Signal Processing. Harmonic Transients in Time Signals. Signal-Noise Separation via Froissart Doublets. Padé Processing for MR Total Shape Spectra from in vivo Free Induction Decays. Exact Reconstructions of Spectral Parameters by FPT. Machine Accurate Padé Quantification and Exact Signal-Noise Separation. Magnetic Resonance Spectroscopy (MRS) and Magnetic Resonance Spectroscopic Imaging in Neuro-Oncology: Achievements and Challenges. Padé Quantification of Malignant and Benign Ovarian MRS Data. Breast Cancer and Non-Malignant Breast Data: Quantification by FPT. Multiplet Resonances in MRS Data from Normal and Cancerous Prostate. General Discussion. Conclusions and Outlooks. Catalog no. K10321, January 2010, 468 pp. ISBN: 978-1-4398-0644-9, $119.95 / £76.99 Also available as an eBook

New & Essential Medical Physics Books from CRC Press

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Medical Physics & Biomedical Engineering Coming soon!

A Practical Approach to Medical Image Processing Elizabeth Berry Elizabeth Berry Ltd, Leeds, UK

Using the freely available software program ImageJ, this text provides instruction on the skills needed to perform filtering and image enhancement techniques used in structured image discrimination. Case studies demonstrate how image processing concepts are applied to reallife situations, such as how to uncover information from images with distortion and pixel-size limitations. A CD-ROM contains the Windows version of ImageJ software, digital images, and documents to be used with the practical activities included in each chapter. Catalog no. C8245, December 2007, 304 pp. ISBN: 978-1-58488-824-6, $88.95 / £41.99

Correction Techniques in Emission Tomography Edited by

Mohammad Dawood, Xiaoyi Jiang, and Klaus Schäfers European Institute for Molecular Imaging, Münster, Germany

“It is refreshing to have a text on emission molecular imaging relevant to animals and human beings with an emphasis on those factors that detract from resolution and quantification. This book implicitly distinguishes between molecular imaging of emitters and molecular imaging provided by magnetic resonance techniques … wherein the response to the injected pattern of the radiofrequency field is measured. … this book shows how researchers have overcome limitations in emission tomography noted 40 years ago and have brought the methods to the goal of high spatial resolution and quantification. Most importantly, these advances have enabled clinically useful applications not available to other diagnostic methods.” —Thomas F. Budinger, University of California, Berkeley

An Introduction to Radiation Protection in Medicine Edited by

This book presents compensation techniques for a range of PET and hybrid PET imaging modalities, including newer hybrid systems currently in preclinical and small animal settings that are being developed for clinical applications. The authors address the problems encountered in emission tomography and their effects on the resulting images.

Jamie V. Trapp

Selected Contents:

Queensland University of Technology, Brisbane, Australia

Introduction. BACKGROUND: Biomedical Applications of Emission Tomography. PET Image Reconstruction. CORRECTIONS TECHNIQUES IN PET AND SPECT: Basics of PET and SPECT Imaging. Corrections for Physical Factors. Corrections for Scanner Related Factors. Image Processing Techniques in Emission Tomography. Motion Correction in Emission Tomography. Combined Correction and Reconstruction Methods. RECENT DEVELOPMENTS: Introduction into Hybrid Tomographic Imaging. MR-Based Attenuation Correction for PET/MR. Optical Imaging. Index.

Tomas Kron Peter MacCullum Cancer Center, Melbourne, Australia

With worked examples and real-world case studies, this text covers the physical and biological background of the subject and addresses the medical situations where radiation is the tool to diagnose or treat human disease. It examines the framework of ICRP radiation protection guidelines, the units and tools used in radiation protection, and the concepts of a system of radiation protection in the workplace. The core of the book presents detailed information on the practical applications of radiation protection in radiology, nuclear medicine, and radiotherapy. Catalog no. C9640, March 2008, 296 pp. ISBN: 978-1-58488-964-9, $83.95 / £41.99

Catalog no. K10659, November 2011, c. 288 pp. ISBN: 978-1-4398-1298-3, $119.95 / £76.99 Also available as an eBook

For more information and complete contents, visit


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Medical Physics & Biomedical Engineering New!

Fundamentals of MRI An Interactive Learning Approach Elizabeth Berry Elizabeth Berry Ltd, Leeds, UK

Andrew J. Bulpitt University of Leeds, UK

“This interactive book with CD by Berry and Bulpitt provides an easy-to-follow, step-by-step process to efficiently assimilate and develop understanding of the fundamentals of MRI. … This will be an invaluable learning tool and resource for those interested in grappling with the complexities of MRI. I would highly recommend this interactive book to those wanting an understanding of MRI.” —Vincent Khoo, Royal Marsden Hospital

Catalog no. C9012, December 2008, 320 pp. ISBN: 978-1-58488-901-4, $61.95 / £34.99

Biomolecular Action of Ionizing Radiation Shirley Lehnert Montreal General Hospital/McGill University, Canada

“… a worthy addition to the library of didactic textbooks in our field. … succinct and easy to read. This book certainly belongs on the bookshelf of anyone who is interested in understanding radiation biology, including residents, graduate students, and postdoctoral researchers. In particular, radiation oncology residents will find this book to be an excellent source of information for understanding the molecular basis of radiation biology.” —Zhong Yun and Joann B. Sweasy, Yale University School of Medicine

Catalog no. IP164, October 2007, 560 pp. Soft Cover, ISBN: 978-0-7503-0824-3 $88.95 / £48.99 Also available as an eBook


Stem Cell Labeling for Delivery and Tracking Using Noninvasive Imaging Edited by

Dara L. Kraitchman Johns Hopkins University, Baltimore, Maryland, USA

Joseph C. Wu Stanford University School of Medicine, California, USA

A comprehensive overview of cell therapy imaging, this book emphasizes the use of medical imaging for therapeutic delivery/targeting, cell tracking, and determining therapeutic efficacy. It presents background information and insight on the major classes of stem and progenitor cells and describes the main imaging modalities and state-of-the-art techniques currently employed for stem cell tracking. The book also offers clinical perspectives on existing and potential uses of stem cells as well as the impact of image-guided delivery and tracking in major organ systems. Catalog no. K10383, October 2011, c. 454 pp. ISBN: 978-1-4398-0751-4, $129.95 / £82.00 Also available as an eBook

Handbook of Anatomical Models for Radiation Dosimetry Edited by

Xie George Xu Rensselaer Polytechnic Institute, Troy, New York, USA

Keith F. Eckerman Oak Ridge National Laboratory, Tennessee, USA

This pioneering work brings together recommendations sanctioned by the ICRP and documents 40 years of cutting-edge work with Monte Carlo codes and radiation protection dosimetry. Assembling the work of nearly all major phantom (computational model) developers around the world, it presents detailed accounts for each wellknown phantom, including those for radiation protection dosimetry applications involving environmental, nuclear power plant, and internal contamination exposures. Related data sets can be downloaded from the authors’ website. Catalog no. C5979, September 2009, 757 pp. ISBN: 978-1-4200-5979-3, $133.95 / £85.00 Also available as an eBook

New & Essential Medical Physics Books from CRC Press

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Medical Physics & Biomedical Engineering


Introduction to Physics in Modern Medicine Second Edition Suzanne Amador Kane Haverford College, Pennsylvania, USA

“… textbooks introducing this topic to students from non-scientific backgrounds need to present the fundamental theory in a manner that is easily grasped yet sufficiently in depth to enable the reader to appreciate its application to real problems. Introduction to Physics in Modern Medicine manages to tread this fine line admirably. … To make this second edition up to date, the author describes a number of recent advances … the contents are thoroughly grounded in well-explained practical examples. … [a] well-researched book that renders complex subject matter thoroughly understandable and enjoyable.” —Contemporary Physics, Vol. 52, Issue 2, 2011

From x-rays to lasers to MRI, developments in basic physics research have been transformed into medical technologies for imaging, surgery, and therapy at an ever-accelerating pace. Physics has joined with genetics and molecular biology to define much of what is modern in modern medicine. Covering a wide range of applications, Introduction to Physics in Modern Medicine, Second Edition builds on the bestselling original to provide medical personnel with an exploration of the physics-related applications found in state-of-the-art medical centers.

New to the Second Edition • Coverage of hybrid scanners for cancer imaging and the interplay of molecular medicine with imaging technologies, such as MRI, CT, and PET • Advances in robotic surgery devices and pills that can film from the inside upon swallowing • Recent forms of cancer treatment, including intensity-modulated radiation therapy and proton therapy • The use of imaging technologies in developing countries

Requiring no previous background of physics, biology, or chemistry and keeping mathematics to a minimum, the applications-dedicated chapters adhere to simple and self-contained qualitative explanations that make use of examples and illustrations. With an enhanced emphasis on digital imaging and computers in medicine, the text gives readers a fundamental understanding of the practical application of each concept and the basic science behind it. The book provides medical students with an excellent introduction to how physics is applied in medicine,while also providing students in physics with an introduction to medical physics. Each chapter includes worked examples and a complete list of problems and questions. That so much of the technology discussed in this book was the stuff of dreams just a few years ago makes this book as fascinating as it is practical, both for those in medicine as well as those in physics who might one day discover that the project they are working on is the basis for the next great medical application. • Introduces state-of-the-art medical physics • Explores recent developments and emerging technologies • Contains case studies, worked examples, and exercises • Offers supporting material on the author’s website

Selected Contents: Introduction and Overview. Telescopes for Inner Space. Lasers in Medicine. Seeing with Sound. X-Ray Vision. Images from Radioactivity. Radiation Therapy and Radiation Safety in Medicine. Magnetic Resonance Imaging.

Catalog no. C9438, April 2009, 448 pp., Soft Cover ISBN: 978-1-58488-943-4, $59.95 / £38.99 Also available as an eBook

For more information and complete contents, visit


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Sensors & Instrumentation


Introduction to Biomedical Engineering Technology Second Edition Laurence Street Rosedale, British Colombia, Canada

Medical devices are often very complex, but while there are differences in design from one manufacturer to another, the principles of operation and, more importantly, the physiological and anatomical characteristics on which they operate are universal. Introduction to Biomedical Engineering Technology, Second Edition explains the uses and applications of medical technology and the principles of medical equipment management to familiarize readers with their prospective work environment. Throughout, the text incorporates real-life examples of the work that BMETs do. Appendices supply useful information, such as normal medical values, regulatory bodies, Internet resources, and information on training programs. Thoroughly revised and updated, this edition includes more examples and illustrations as well as end-of-chapter questions to test readers’ understanding.

New to the Second Edition • A wider range of devices, an expanded section on equipment management, and more information about test equipment • New, integrated end-of-chapter questions • More illustrations and real-life examples of BMET work, including the adventures of “Joe Biomed” and his colleagues • New appendices with information about normal medical values, regulatory bodies, educational programs in the United States and Canada, international BMET associations, Internet resources, and lists of test equipment manufacturers

Catalog no. K12781, October 2011, 360 pp. ISBN: 978-1-4398-6058-8, $89.95 / £56.99


Written by an experienced biomedical engineering technologist (BMET), the book describes the technological devices, various hardware, tools, and test equipment used in today’s healthcare arena. Photographs of representative equipment; the technical, physiological, and anatomical basis for their function; and where they are commonly found in hospitals are detailed for a wide range of biomedical devices, from defibrillators to electrosurgery units.This accessible text supplies an essential overview of clinical equipment and the devices that are used directly with patients in the course of their care for diagnostic or treatment purposes. The author’s practical approach and organization, outlining everyday functions and applications of the various medical devices, prepares readers for situations they will encounter on the job. • Describes the day-to-day work of BMETs using extensive examples • Offers chapter summaries and questions to aid in reader comprehension • Contains more than 360 illustrations, including a 16-page color insert • Includes a 16-page grayscale insert with photographs of real-life equipment problems • Provides appendices listing normal medical values, biomedical associations, test equipment manufacturers, helpful Internet resources, and more

Selected Contents: Introduction. Diagnostic Devices: Part One. Diagnostic Devices: Part Two. Diagnostic Devices: Part Three. Diagnostic Imaging. Treatment Devices: Part One. Treatment Devices: Part Two. Treatment Devices: Part Three. Biomedical Engineering Technologist (BMET) Work. Testers and Tools. Batteries, Radiation, and Computers. Technology Management. Appendices. Index.

New & Essential Medical Physics Books from CRC Press

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Sensors & Instrumentation New!

Basic Transport Phenomena in Biomedical Engineering Third Edition Ronald L. Fournier University of Toledo, USA

This book explores fundamental engineering and life science principles to uncover key concepts in biomedical engineering transport phenomena. It reviews the basics of thermodynamics and then examines the physical properties of body fluids and the cell membrane. The book also covers the properties of blood, solute transport, pharmacokinetic analysis, extracorporeal devices, tissue engineering, and bioartificial organs. Each chapter ends with problems to help clarify the material. • Provides an introductory-level text for readers in bioengineering, chemical engineering, mechanical engineering, and the life sciences • Presents a basic understanding and the theories of transport in biological systems • Builds on this knowledge base to show real-world applications in the development and design of artificial organs, drug delivery systems, and tissue engineering • Includes numerous examples with a discussion of the numerical methods used to solve the problems • Contains an extensive bibliography of the research literature that supports the material in the text • Supplies numerous illustrations and problems that offer readers the opportunity to explore in greater detail the material covered in each chapter

Biomedical Sensors and Instruments Second Edition Tatsuo Tagawa Waseda University, Tokorozawa, Saitama, Japan

Toshiyo Tamura Chiba University, Chiba, Japan

P. Ake Oberg Linköping University, Sweden

The living body is a difficult object to measure: accurate measurements of physiological signals require sensors and instruments capable of high specificity and selectivity that do not interfere with the systems under study. As a result, detailed knowledge of sensor and instrument properties is required to be able to select the best sensor from one of the many designed to meet these challenges. From the underlying principles to practical applications, this updated edition provides an easyto-understand introduction to the various kinds of biomedical sensors. It presents state-of-the-art discussions on sensors for the measurements of pressure, flow, motion, temperature, heat flow, evaporation, biopotential, biomagnetism, and chemical quantities. • Organizes topics to make it easy to find the best possible choice of sensors for each measurement situation • Includes more than 300 updated figures and tables that facilitate an intuitive understanding • Presents numerous examples of sensor applications that demonstrate practical methods of research • Provides references at the end of each chapter for further study

Selected Contents:

Selected Contents:

Introduction. A Review of Thermodynamic Concepts. Physical Properties of the Body Fluids and the Cell Membrane. The Physical and Flow Properties of Blood. Solute Transport in Biological Systems. Pharmacokinetic Analysis. Extracorporeal Devices. Tissue Engineering. Bioartificial Organs. Index.

Fundamental Concepts. Pressure Measurements. Flow Measurement. Motion and Force Measurement. Temperature, Heat Flow, and Evaporation Measurements. Bioelectric and Biomagnetic Measurements. Chemical Measurements.

Catalog no. K11304, September 2011, 483 pp. Soft Cover, ISBN: 978-1-4398-2670-6 $89.95 / £44.99 Also available as an eBook

Catalog no. 9078X, March 2011, 423 pp. ISBN: 978-1-4200-9078-9, $139.95 / £89.00 Also available as an eBook

For more information and complete contents, visit


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Related Books of Interest New!

Intellectual Property in Academia

Coming soon!

A Practical Guide for Scientists and Engineers

Tianhu Lei

Edited by

Nadya Reingand CeLight, Inc, Silver Springs, Maryland, USA

This book provides a practical understanding of intellectual property basics relevant in an academic environment. It describes the process of performing a comprehensive prior art search, determining business value, filing for a patent, licensing to companies, and using follow-up patents to create a valuable portfolio. The text also covers starting a new business, with cases of student inventions that led to successful startups, and reflects recent changes in application procedures. A special chapter addresses issues in copyright law relevant to academics, such as determining what is copyrightable in reporting an industry-sponsored project. • Provides complete step-by-step guidance on how to proceed with inventions in an academic environment • Reflects recent changes in patent law and filing procedures, such as electronic filing, accelerated submission, and online prior art searching • Gives detailed instructions on patent filing, prosecution, and intellectual property portfolio management • Addresses the critical issue of ownership of the legal rights to intellectual discoveries developed under various types of contracts • Shows the IP limitations associated with different types of contract funding

Selected Contents: Introduction to Intellectual Property in Academia. Patent Basics. Prior Art Searching. Valuation of Technology-Based IP in Academia. Drafting a Patent Application. Electronic Filing of US Patents. Filing University Patent Applications through an Office of Technology Transfer. University Patent Revenue Generation: Case Studies. Copyright. Catalog no. K11674, October 2011, c. 296 pp. Soft Cover, ISBN: 978-1-4398-3700-9 $49.95 / £31.99 Also available as an eBook


Statistics of Medical Imaging University of Pennsylvania and Children’s Hospital, Philadelphia

Providing a unified framework for study, this book reflects the extensive work being done in the statistical aspects of medical imaging. It presents a complete look at medical imaging and statistics, from the statistical aspects of imaging technology to the statistical analysis of images. The author discusses the statistical principles underlying medical imaging and offers reference material for researchers involved in the design of new technology. Numerous real examples, algorithms, and illustrations are included throughout. The text also includes exercises drawn from the author’s many years of experience studying the statistics of medical imaging. • Provides a comprehensive overview of the statistical aspects of medical imaging • Covers the physics and mathematics of imaging, statistical aspects of imaging technology, and the statistical analysis of images • Features a wealth of real examples to illustrate the methods described • Includes algorithms for many of the methods, enabling their practical use

Selected Contents: IMAGING PHYSICS AND MATHEMATICS: Introduction. X-Ray Computed Tomography. Magnetic Resonance Imaging. Magnetoencephalography. IMAGING STATISTICS AND IMAGE STATISTICS: Statistics of X-Ray Computed Tomography. Statistics of Magnetic Resonance Imaging. Statistics of Magnetoencephalography. Statistics of NonDiffraction Computed Tomography. STATISTICAL IMAGE ANALYSIS: Stochastic Image Models. Model-Based Image Segmentation. Magnetoencephalography Data Analysis. Applications of Image Analysis. Appendices. Catalog no. C8842, December 2011, c. 416 pp. ISBN: 978-1-4200-8842-7, $99.95 / £63.99 Also available as an eBook

New & Essential Medical Physics Books from CRC Press

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Related Books of Interest Radiation Threats and Your Safety Radiation Risks in Perspective Kenneth L. Mossman Arizona State University, Tempe, USA

“…a useful source of information on how risks, and especially radiological risks, are assessed, evaluated and communicated by/to a variety of stakeholders … The book contains a great deal of interesting information and is certainly thought-provoking. It also contains some useful cross-references to chemical risks and how these are addressed. …” —Ron Brown, Journal of Radiological Protection

“It imposes a minimum burden of mathematical symbols, freshens graphs from the older literature to make them easy for a broad audience to understand, and provides simply formatted tables that list the main concepts as they are introduced. … The mixing of a studied description of risk management with advocacy, debate, and some stridency makes for an exciting read. … gives anyone interested in risk management policy the perspective of a well-read, involved, and spirited actor in the field.” —Mark P. Langer, American Journal of Roentgenology, (189) 1

This book uses radiological risk as a model to illuminate the fundamental problems and possible solutions to public perception, reaction, and policy when faced with possible health risks. With supporting case studies, it discusses current assessment methods, prioritizing of expenditure, and the public’s extremist tendency to demand zero risk tolerance.

Selected Contents: Introduction. Risky Business. Scientific Guesswork. No Safe Dose. Uncertain Risk. Zero or Bust. Misplaced Priorities. Avoiding Risk. Radiation from the Gods. Hold the Phone. PR Campaign: Proportion, Prioritization and Precaution. Glossary. Index. Catalog no. 7977, October 2006, 207 pp. ISBN: 978-0-8493-7977-2, $102.95 / £65.99 Also available as an eBook

A Guide to Preparation and Response for Professionals and Community Armin Ansari Centers for Disease Control and Prevention, Atlanta, Georgia, USA

“The author … has skillfully assembled a body of knowledge on preparedness and response to accidental and intentional radiological and nuclear incidents targeted at concerned citizens and early responders. … a good contribution on the subject. It is a good resource for both perspective and plain-language explanations of sometimes complex subjects. I would recommend it to health physicists, emergency managers, and those involved with public communication.” —George J. Vargo, Health Physics, June 2011

“I was very impressed with the book and would strongly recommend it … . The book is well written and places many very intimidating subjects in simple language. … The book also contains a number of unique items, or perhaps little gems, such as insights not commonly found in the literature nor echoed in circles of health physicists. … I found the book to be well written and of high quality with a potentially wide audience who could substantially benefit from reading and using it.” —Nuclear Technology, Vol. 171, August 2010

Selected Contents: Introduction. Radiation, The Environment, and Us. The Basics. Health Effects of Radiation. Types of Radiation Emergencies. Government Response to Radiation Emergencies. Medical Response to Radiation Emergencies. Radiation Drugs. Protecting Yourself from Radiation. The Family Emergency Plan. Environmental Effects of Radiation Emergencies. Psychosocial Impact. Professional Response. Community Preparation. Living with the Threat. Catalog no. C8361, October 2009, 344 pp. ISBN: 978-1-4200-8361-3, $71.95 / £45.99 Also available as an eBook

For more information and complete contents, visit


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Related Books of Interest Quantitative Understanding of Biosystems An Introduction to Biophysics Thomas M. Nordlund University of Alabama at Birmingham, USA

“The book contains a beautiful review of essential physics for understanding biological systems, particularly at the molecular scale, emphasizing that which is rarely taught in standard physics classes: how to think like a physicist. The chapters on quantum mechanics and the interaction of photons with biological systems are particularly welcome, and set this book apart. …” —Ernest Barreto, George Mason University

“A superb pedagogical textbook about the behavior and properties of the microscopic structures that form the essential building blocks of living systems. … Full-color illustrations aid students in their understanding of how to use mathematical tools to better grasp, analyze, and project solutions to problems involving the quantitative characterization of biosystems. … an excellent college text or self-instruction manual for advanced biophysics science students.” —Midwest Book Review, May 2011

This color text provides a hands-on understanding of the movement of microorganisms, reviews the necessary mathematics, discusses quantum mechanics in biosystems, and describes the transition from discreet random walks to continuum diffusive motion. A CD-ROM includes “active” versions of Excel graphs and diagrams from the text, along with links to mathematical and biological/biochemical source data.

Selected Contents: Introduction, Approach, and Tools. Structure and Function. Biological Activity: Quantum Microworld. Biological Activity: (Classical) Microworld. Appendices. Glossary. Further Resources. Index. Catalog no. 89772, March 2011, 583 pp. ISBN: 978-1-4200-8972-1, $89.95 / £57.99 Also available as an eBook


Ultrasonics Fundamentals, Technologies, and Applications, Third Edition Dale Ensminger Sunnyvale, California, USA

Leonard J. Bond Pacific Northwest National Laboratory, Richland, Washington, USA

Reviewing the scientific basis behind recent improvements, this book presents a completely revised and expanded examination of the state of modern ultrasonics. With new and additional figures and references, the third edition of this bestselling industry reference discusses the full breadth of ultrasonics applications for industrial and medical uses. The book provides a unique and comprehensive treatment of the science and technology behind the latest advancements and applications in low and high power implementations. Coverage combines fundamental physics, an analysis of sensors and transducers, and the systems required for the full spectrum of industrial, nondestructive testing and medical and biomedical uses. It also covers both mainstream and the more unusual and obscure applications of ultrasound.

Selected Contents: Ultrasonics: A Broad Field. Elastic Wave Propagation and Associated Phenomena. Fundamental Equations Employed in Ultrasonic Design and Applications. Design of Ultrasonic Horns for High Power Applications. Basic Design of Ultrasonic Transducers. Determining Properties of Materials. Nondestructive Testing: Basic Methods and General Considerations. Use of Ultrasonics in Nondestructive Testing and Evaluation of Metals. Use of Ultrasonics in the Inspection and Characterization of Nonmetals. Imaging, Process Control and Miscellaneous Low-Intensity Applications. Applications of High-Intensity Ultrasonics: Basic Mechanisms and Effects. Applications of High-Intensity Ultrasonics Based on Mechanical Effects. Applications of Ultrasonics Based on Chemical Effects: Sonochemistry. Medical Applications of Ultrasonic Energy. Appendices. Glossary. Catalog no. DK8897, September 2011, 765 pp. ISBN: 978-0-8247-5889-9, $199.95 / £127.00 Also available as an eBook


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New & Essential Medical Physics Books from CRC Press, 2011