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90 Infection Infection is a well-recognised cause of morbidity and mortality in preterm infants. Figures 24 and 25 show the percentage of babies (< 28 weeks and 28-31 weeks gestation respectively) who suffered from one or more episode of late onset sepsis, with available ANZNN data as a comparison. The percentage of babies less than 28 weeks gestation who suffered from one or more episodes of late onset sepsis appeared to be trending up from 2008 to a peak of 53.6% in 2011 subsequently this decreased to a low of 13.8% in 2013, increasing in 2014 to 31.6%. The percentage of babies born between 28-31 weeks gestation who had one or more episodes of

sepsis appears more stable over the reported time period although the lowest percentage (1.9%) of episodes of infection was also been seen in 2014. There has been a quality improvement initiative undertaken to improve the way central lines were inserted and maintained during this period, Central Line Associated Bacteria (CLAB) which is a regular change of staff shift check and is temporally associated with the decrease percentage of babies that have had an episode of sepsis. Routine Lactoferrin use may also have contributed to the decreased incidence of sepsis seen in 2013 and 2014.

percent (n=2) and 8.7% (n=2) of babies less than 28 weeks being admitted to the Middlemore Hospital Neonatal Unit in 2013 and 2014 respectively suffered from early onset sepsis. For babies 28-31 weeks gestation admitted to the Middlemore Hospital Neonatal Unit 2.6% (n=2) suffered from early onset sepsis in 2014.

Early onset sepsis is less common than late onset sepsis. Seven

45

100

40

90 80  

Number of  babies  

35

70

30

60

25

50 20  

40

15

30

10

20

5 0  

% of  babies  with    1  or  more  episodes  of  sepsis  

Figure 24. Number of babies born at < 28 weeks gestation, admitted to the neonatal unit, and the percentage who suffered from one or more episodes of late onset sepsis

total babies  

% sepsis   MMH  

%sepsis ANZNN  

10

2007 2008   2009   2010   2011   2012   2013   2014  

0

Source: Data provided by Middlemore Hospital Neonatal Unit 2015. Collected as per ANZNN guidelines. Note: ANZNN= Australia and New Zealand Neonatal Network, MMH=Middlemore Hospital

2014 2015 maternity quality and safety programme  

This Annual Report (2014-2015) covers the continued progress and initiatives undertaken over the last 12 months as part of the Maternity Qua...

2014 2015 maternity quality and safety programme  

This Annual Report (2014-2015) covers the continued progress and initiatives undertaken over the last 12 months as part of the Maternity Qua...