Issuu on Google+

N E WS

PAGE 8 THURSDAY, APRIL 18, 2013

THE DAILY PENNSYLVANIAN

Breakthrough tech at Say Goodbye to Penn cancer center Your Seniors The Center for Personal Diagnostics to expand repertoire of cancer-detecting tests BY DINA MOROZ Staff Writer

Place an ad in the DP’s

Graduation Goodbyes

Issue

Submit by: April 22nd Publication Date: May 10th For more information, call us at 215-898-6581 or email: advertising@theDP.com

Classifiedads FORRENT

FORRENT

503 South 42nd St. 1st floor. Large efficiency. Large porch. Price negotiable, all utilities included. Available 8/1. 267‑872‑5154.

4612 BaltimoRe ave. 2nd floor, rear. 1BR, large kitchen & L/R. Recently reno‑ vated. Available now! 267‑ 872‑5154.

SwaRthmoRe: 2 aptS for rent. All utilities included, 3 blocks to train, available now. (1) 1BR, new eat‑in kitchen, refinished wood floors, $850/month. (2) Charming studio apt with sunroom, first floor, $675/month. Call 610‑543‑ 7539. No smoking, pets.

4614 BaltimoRe ave. Studio. 2nd Floor Front. Available 6/1. 267‑872‑5154 Find houSing RentalS at www.sublet.com. Short or Long Term. Furnished and unfurnished. Advertise Avail‑ able Rentals Free. www. sublet.com 503 S. 42nd Street. Victo‑ rian house, very large rooms. University students preferred. 8BR, 3.5BTH, ceil‑ ing fans, W/W carpet, stor‑ age room, W/D, backyard, porch. Finished basement, 2 kitchens, 2 refrigerators. Alarm system. Available 5/1. 267‑872‑5154.

FORRENT

WANTED

penn oFF‑campuS Apartments. Reserve yours today @ www.BergerProperties.org 215‑771‑1036.

SUBLET

Great 1br apt

laRge BedRoom in 7 bedroom house at Locust and 41st. Available summer and/or fall $800/month. email klbelgrad@gmail.com

SUBLET

Seeking Special egg Donor. $25,000. Help Caring Ivy League Couple! Seeking Penn student, Grad Student or Graduate, athletic, 5’7” to 5’10” tall, German, Eastern European, English or Irish descent (other heritages con‑ sidered), pretty, athletic, fun, kind, age 21‑32. Please be our Donor. Medical Proce‑ dure really easy and in NYC vicinity. Send picture, ré‑ sumé and where you can be reached during school year and during summer to: Donors for Kindness, P.O. Box 9, Mt. Kisco, NY 10549

please recycle this dp!

1 bedroom, 1 bathroom & living room space available in fully furnished apartment. Available May 10 - August 10. Rent $1,500/month, price negotiable. Gym in building. Train station close by. Contact Bessie Greene: (267) 273-4495 (215) 222-0200

bessie.greene@hilton.com

SUDOKUPUZZLE

� � � � � � � � �

� � � � � � � � �

� � � � � � � � �

� � � � � � � � �

� � � � � � � � �

� � � � � � � � �

� � � � � � � � �

Skill Level: Complete the grid so each row, column and 3-by-3 box (in bold borders) contains every digit 1 to 9.

� � � �

Solution to Wednesday’s Puzzle ������

��������������������������������������

� � � � � � � � �

� � � � � � � � �

� � � � � � � � �

� � � � � � � � �

Now part of the Apartments @ Penn family of properties, 117 S. 43rd Street!

Call us today for details! sponsored by:The New York Times Syndication Sales Corporation

620 Eighth Avenue, New York, N.Y. 10018 www.apartmentsatpenn.com For Information Call: 1-800-972-3550 For Release Thursday, April 18, 2013

215.222.0222

NEWYORKTIMESCROSSWORDPUZZLE Edited by Will Shortz

� � � � � � � � �

� � � � � � � � �

� � � � � � � � �

� � � � � � � � �

� � � � � � � � �

� � � � � � � � �

Create and solve your Sudoku puzzles for FREE.

Play Sudoku and win prizes

at:

prizesudoku.com

The Sudoku Source of

“Daily Pennsylvanian”.

No. 0314

Crossword

Across

2429 LOCUST, Apt. 318

������

to prevent the disease from returning. C y t oge net ic s — w h ic h looks at the DNA of chromosomes — was discovered at Penn more than 50 years ago. However, this analysis does not detect abnormalities in the majority of patients. “S o t he quest ion is: is there a way to identify abnormalities in those patients with normal chromosomes? And that’s what the Center for Personalized Diagnostics is doing for us,” Luger said. “So far we’ve looked at about 30 patients with acute leukemia and 95 percent of them have had genetic abnormalities identified that were not done by traditional tests.” She explained that the goal is to develop novel therapies that are less toxic and allow for treatment w ithout the side effects that result from chemotherapy. In addition to this goal, CPD is currently work ing on gene panel based tests that will hopefully be able to detect a variety of cancers via a simple blood test, according to Roth. “It is thr illing for us to be able to offer new hope to patients. Our entire team is very gratified by our early experience. This is working out even better than we had hoped,” he said.

(215) 898-6581

www.theDP.com/classifieds

1BR apaRtment. 3400 Sansom St., across Penn Law. Call John at Avril 50, 215‑222‑6108 or avril.fifty@ verizon.net

4614 BaltimoRe ave. 3rd floor. Very large 3BR, two full bathrooms, balcony, large L/R, eat‑in kitchen, A/C Available 5/1 or 6/1. 267‑872‑ 5154.

Pen n’s Cent er for Per sonalized Diagnostics uses cutting-edge, genome-wide tests to see the rare mutations that even high-power microscopes cannot detect. The CPD — a joint venture between the Department of Patholog y and Laborator y Medicine and the Abramson Cancer Center —began testing for patients on Feb. 14. “On a day to day basis, we receive tumor specimens that the pathologists have already reviewed and … we extract the DNA from the samples we receive,” Robert Daber, the Technical Director of Clinical Genomics at the Center for Personalized Diagnostics said. “We then sequence a large number of genes from the genome and look for mutations that are present in the tumor specimens that then help the clinicians understand how to treat their patients better.” David Roth , chair of the depa r t ment of Pat holog y and Laborator y Medicine , j o i ne d P e n n a l mo st t w o years ago and created CPD

in close collaboration with Chi Dang of the Abramson Cancer Center. “This technolog y, called massively parallel sequenci ng , or ‘ ne x t ge ne r at ion sequencing,’ allows us, for the first time, to determine the nucleotide sequences of many genes simultaneously,” he said in an email. “In our first few weeks of applying these tests, called cancer gene panels, we have already found mutations in samples from several patients that are very rare in those particular cancers, and would not have been looked for using single gene tests.” Since CPD began operating two months ago, tests in 80 percent of patients revealed genetic mutations — findings that allow for more efficient treatment options. The center currently focuses on four disease areas — acute myeloid leukemia, brain tumors, lung tumors and melanoma — but plans to expand tests to other diseases in the near future. Director of the Leukemia Program at the Abramson Cancer Center Selina Luger e x pl a i ne d t h at mo st p a tients with A ML receive a standard treatment of induction chemotherapy to treat the disease. Once patients are in remission, they are given more chemotherapy

25 It starts in  March: Abbr.

56 Open a tad 57 Roof with  removable panels 26 It, in Italy   5 Short 58 “… ___ the  29 Showy bloom,    8 ___ folder frumious  to flower  Bandersnatch!”:  enthusiasts 12 Hard-to-tolerate  Carroll sort 30 Be half-asleep 59 Italian port 13 Allegheny plum,  32 Terrier on the  e.g. 60 “___ Smile”  silver screen (1976 top 5 hit) 14 Prevail upon 33 Middle of the  61 ___ Miss quote 15 French cleric 37 2009 “Star Trek”  62 Like plow horses 16 Superior of a  villain bos’n Down 38 Vertebral 17 Actress Sorvino   1 L i k e   t h i s 39 Unites after a  18 Beginning of   break   2 Patient, cheerful  a quote by 3-/31sorts, it’s said 41 Assay, say Down on which    3 See 18-Across Stephen Colbert  42 Old French coin commented   45 Like some media   4 Kilt feature “I hope teenagers    5 John Paul II, for  47 Some electric  aren’t watching  one cars this right now”   6 Pueblo people 49 Golf club V.I.P. 21 Fulfilled   7 1983 title role  50 End of the quote 22 Cerium and  for Barbra  samarium are  53 Works at the  Streisand rare ones National Gallery   8 Tally 23 Classic prize 55 Indian attire   9 Flower from  which an oil is  ANSWER TO PREVIOUS PUZZLE derived L O N G F A C T O S C A N 10 Accepted A J A R I G L O O P O G O 11 Player of Eddie  M A D A M B O U G H T A F L Y in “The Rocky  P I A N O R E O A D F E E Horror Picture  Show” U R S A F L E E T S D E F L A T E R M O U S E 13 One of three  A L L E L E I O U S M E W choices in a kids’  game B I A S L E D O N D I V A S A G O L E O D A R L I N 19 Consoling word  B A B A O F S E V I L L E that bears  repeating? L I E F O R O D I E O H A R E G A L A S C A P 20 Quick to the   B O R I S G O O D E N O U G H helm O P E C T O N E R F L E E 24 Truck renter S E R A O P E R A F L E W 27 Went 4-0, say   1 Bass technique

1

2

3

4

5

6

7

8

12

13

14

15

16

17

18

19

20

22

23

25

26

27

28

30 33

34

10

11

43

44

21 24

29 31

35

32 36

37

38

39

40

45

41

42

46

49 53

9

50 54

47 51

48

52

55

56

57

58

59

60

61

62

puzzle by mike buckley

28 Actor Davis

35 French flag

48 Wild guesses

30 Indian attire

36 Went out with

31 See 18-Across

40 Went out with

51 Comic who said  “A conservative  is someone  who believes in  reform. But not  now”

33 1940s quartet  42 Wood in Tolkien  with the #1 hit  films “Into Each Life  43 Sporty Chevy Some Rain Must  44 Log-in need Fall,” with “the” 34 Eligible one in   El Salvador

52 Exact 46 Stockholder on a  54 Day ___ ranch?

For answers, call 1-900-285-5656, $1.49 a minute; or, with a credit card, 1-800-814-5554. Annual subscriptions are available for the best of Sunday crosswords from the last 50 years: 1-888-7-ACROSS. AT&T users: Text NYTX to 386 to download puzzles, or visit nytimes.com/mobilexword for more information. Online subscriptions: Today’s puzzle and more than 2,000 past puzzles, nytimes.com/crosswords ($39.95 a year). Share tips: nytimes.com/wordplay. Crosswords for young solvers: nytimes.com/learning/xwords.


Thedailypennsylvanian