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CCM Data & Primary Intelligence

Future of Green Biotechnology in China

The First Edition

Prepared by:

Guangzhou CCM Information Science and Technology Co., Ltd . Guangzhou, P. R. China

Oct. 2009

Copyright by Guangzhou CCM Information Science and Technology Co., Ltd. (P. R. China) Any publication, distribution or copying of the content in this report is prohibited. Website: http://www.cnchemicals.com Tel: +86-20-37616606 Fax: +86-20-37616968 Email: econtact@cnchemicals.com

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CCM Data & Primary Intelligence Description: This report is the unique and latest one available in the world to provide good understanding about Green Biotechnology (GB) in China and to find out business opportunities in this field. The first edition of this report is finished in October 2009. Green biotechnology (GB) is mainly based on genetically modified technology and fermentation technology. Over the last thirty years, China’s GB industry has been developing stably. Chinese scientists have applied biotechnology techniques to develop many novel crop varieties that are suited to local farming conditions and can cope with challenges. More and more products in agriculture have adopted biotechnology, and production scale has been enlarged. Increasing use of green biotechnology in agricultural production can bring a lot of benefits. Driven by its substantial benefits for people, environment and economy, China’s GB industry has witnessed fast development and has played an increasingly important role in Chinese economic growth. However, the overall development of China’s GB industry remains in growth stage, and still has an enormous gap compared with developed countries. This report provides detailed information and systematic data from perspectives of production, market, high level overview, future forecast and opportunities on the sub-categories such as genetic-modified crops, bio-pesticides, bio-fertilizers, bio-feeds, transgenic animals, animal vaccines, bio-reactors, etc. Reasons to carry out this research Green biotechnology represents agriculture’s development trend Government encourages Biotechnology R&D and applications in agriculture Increasing concern over food safety Supply shortage of food and energy Huge opportunities What is covered? Sub-categories of green biotechnologies in China: Genetically modified crops, bio-pesticides, bio-fertilizer, biological veterinary medicine, biological feeds, plant/animal bioreactors, etc. For all the sub-categories, market data, major players, technical suppliers, technologies or R&D situations are included. Over 30 GB-related products falling in the sub-categories mentioned above are summarized specifically. Overview of China’s green biotechnology: A higher level analysis and summary Future prospects of each category of green biotechnologies; Key influencing factors and commercial opportunities

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CCM Data & Primary Intelligence Opportunities and recommendations Profiles of major players and research institutes Related policies and regulations What benefits one will get? Gain a clear understanding of the industry landscape and latest developments in R&D, production, technology advancement and future trends in China’s green biotechnology Precisely position development stages of key GB products or sub-categories in China based on basic data and latest infomation Acquire reasonable and constructive suggestions on market opportunities in China’s GB fields Get a thorough analysis of the marketplace for green biotechnology in China, current trends and future growth prospects Know more about how innovative players and research groups are conducting innovation, collaboration and achieving commercial success in China Credibility Scientific methodologies and varieties of data sources are adopted to ensure credibility. Major steps adopted to formulize this report: Desk research Telephone interviews with GB producers and GB researchers Email and on-line tools adopted to communicate with players/researchers Series of internal discussions in order to analyze the data and draw conclusions Forecast Report generation The data collected and compiled were sourced from: Published articles from periodicals, magazines, journals, the third-parties’ database Government statistics Primary information obtained from Tel-interviews, on-line chats, emails, questionnaires, etc. Comments from industrial experts CCM’s database Third-parties’ database Information from the Internet Data from various channels has been integrated and cross-checked to make this report as precise and credible as possible. Who needs to subscribe to this report? Biotechnology companies Update your knowledge and be well informed of latest developments in market, R&D and Website: http://www.cnchemicals.com Tel: +86-20-3761 6606

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CCM Data & Primary Intelligence applications of China’s green biotechnology Discover the potentialω opportunities for green biotechnology in China Benefit from a thorough review of new applications for bio-based products and assess the potential for further growth Agricultural companies Learn how green biotechnologies will change the status quo and future of agriculture Keep close track of recent developments of green biotechnology in China Agricultural product processors, end users of GB products Know what superior and novel GB products you can get from China and then creat more value to your customers and grasp commercial opportunities Research organizations and academies Keep an close eye on latest technical developments and newest scientific breakthroughs Identify the most significant commercial opportunities to steer future research

Main content: No.

I II III III-1 III-1.1 III-1.2 III-2 IV IV-1 IV-1.1 IV-1.2 IV-1.3 IV-1.4 IV-1.5 IV-2 IV-2.1 IV-2.1.1 IV-2.1.2 IV-2.2 IV-2.3 IV-3

Content Executive summary Methodology and sources Introduction to green biotechnology in the world Overview of China’s green biotechnology industry Policies and influencing factors Policies Regulations Some government support policies Influencing factors Markets of green biotechnology in China Genetically modified crops and their breeding Overview Insect-resistant cotton (Bt cotton) Other genetically modified crops R&D progress Problems existing in China’s GM crops Future forecast Clone and transgenic animals Overview Applications Applications of animal cloning technology Applications of transgenic animal technology R&D progress Future froecast Biological pesticide Overview

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Page 1 7 9 13 16 16 16 17 19 21 21 21 22 27 30 32 33 37 37 38 38 38 40 41 42 42

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CCM Data & Primary Intelligence IV-3.1 IV-3.2 IV-3.3 IV-3.4 IV-3.5 IV-4 IV-4.1 IV-4.2 IV-4.3 IV-5 IV-5.1 IV-5.2 IV-5.3 IV-5.4 IV-6 IV-6.1 IV-6.2 IV-6.3 IV-6.4 IV-7 IV-7.1 IV-7.2 IV-7.3 V VI VII VII.1 VII.2

Bio-insecticide Bio-fungicide Biological plant growth regulator R&D progress Future forecast Bio-fertilizer(microbial fertilizer) Overview Bio-fertilizer production in China R&D progress Future forecast Biological veterinary medicine Overview Animal vaccines Other biological veterinary medicine R&D progress Future forecast Biological feed additives Overview Feed enzyme preparations Microbial feed additives R&D progress Future forecast Others Plant bioreactor Animal bioreactor Plant tissue culture Recent industry activity in China Conclusion and recommendation Profiles of major players and researchers Profiles of major players Profiles of major researchers

49 57 61 62 63 68 68 69 79 80 83 83 84 89 89 90 93 93 94 102 103 104 107 107 108 109 112 113 115 115 129

Executive summary: Green biotechnology (short for GB), also known as agriculture biotechnology, is a rapidly expanding field with modern biotechnology involving introduction of foreign genes into economically important plant species, which can create benefits such as crop improvement and production of novel products. China’s GB industry has played an increasingly important role in China’s economic growth over the last thirty years with its rapid development gradually. Especially during the past decade, domestic GB has made considerable progress in production scaling-up, technology innovations and applications.

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CCM Data & Primary Intelligence In recent several years, with frequent outbreak of pest disasters and stricter environmental requirements, Chinese government is taking more and more measures to promote GB industry, which leads to huge market value. GB industry in China in following fields has witnessed significant development and progress. - Genetically modified crops and their breeding GM crops is the most fast-growing field among all applications of GB in China and has seen increasingly brighter prospect under governmental guidance. As of 2009, Chinese government has approved commercial production of six GM crops, namely cotton, tomato, morning-glory, sweet pepper, papaya and poplar, but currently, only GM cotton has achieved commercialized plantation at home. - Clone and transgenic animal Development of clone animal and transgenic animal is still under research stage in China though many technology breakthroughs have been made in this field. Currently, there is no related product sold in the market, due to various reasons with ineffective technology and R&D ability the most outstanding. - Biological pesticide Chinese biological pesticide industry is another rapid-developing field adopting GB techniques in China. Especially in the past decade, biological pesticide application is increasing largely. Total output of Chinese biological pesticides has also increased rapidly with CAGR of XX% from 2004-2008. With XX biological pesticide producers, most Chinese biological producers are universally small-scale, among which only XX~XX biological pesticide companies in China have annual sales value exceeding USDXX million. - Bio-fertilizer China’s bio-fertilizer industry has scored many achievements and been optimistic in recent several years, with its increasing consumption volume, seeing CAGR of XX% from 2005 to 2008. There were totally XX bio-fertilizer manufactures in 2008 and about XX have been approved by and cooperated with the Ministry of Agriculture. Most of them are of small scale with total output of about XX million tonnes in 2008, taking up only XX% of total fertilizer output in China. - Biological veterinary medicine In China, biological veterinary medicine generally includes animal vaccines, antiserum, toxoid, etc, among which animal vaccines accounts for about XX% of the total output in 2008, and thus the Website: http://www.cnchemicals.com Tel: +86-20-3761 6606

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CCM Data & Primary Intelligence animal vaccine is mainly introduced. Total animal vaccines capacity has reached XX billion doses in recent several years, far higher than the annual demand of about XX billion doses in 2008. There are XX produce biological veterinary products in China, accounting for XX% of total veterinary medicine manufacturers, and XX have been GMP certified. - Biological feed additive China as one of the leading feed stuff producers in the world has largely developed biological feed additives in the past few years with expanding application and rising consumption. The feed enzyme preparation in particular, has made great breakthroughs with technological improvement in this field. Though feed enzyme preparation in feed production application still faces many problems in screening strains and fermentation technology, it’s expected to witness fast development in the future especially with improved technology in genetic engineering. At present, there are about XX feed enzyme preparation manufacturers in China, with climbing output and market value. From 2006-2008, CAGR for feed enzyme preparation out was achieved at XX%. - Others Plant bioreactor, animal bioreactor and plant tissue culture are also important application areas of GB in China. For plant bioreactor and animal bioreactor, although there are no commercial products sold in the market yet, some potential products are expecting bright prospect. For the plant tissue culture industry, it has been booming for several years, bringing many commercial opportunities. By 2008, many plant tissue culture technologies had been put into application, and the most valuable technologies in China are crop tissue culture and flower tissue culture.

Character of CCM' Report: The aim of this report is to provide powerful assistance to the strategy group and the management team in making correct decision as how to penetrate the ever-increasing China market and how to catch the maximum commercial opportunities. The report is formulated independently by CCM’s professional market researchers, based on the first-hand and primary data which are analyzed by scientific methodology, confirmed with both manufacturers/end users/traders and legal authorities, and presented in a logic way. Sample pages

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................ -

Market situation

In the past few years, development level of different fields for GB industry takes on different looks. In China, GM crops is the most fast-growing field among the seven, although there is only Bt cotton has achieved commercialized plantation, meanwhile China has been importing large quantities of GM soybean annually, therefore, Chinese GM crops market also constitutes the largest proportions in the past few years, and the leading position is expected to continue in coming few years. ………… Table II.1 Production situation of GB industry by field Item

Categories

Major producers Shenzhen

Biocentury

Total output’ 2008

Market size' 2008

Trangene

Genetically (China) Co., Ltd., Origin Agritech Co.,

XX

XX

XX

XX

XX

XX

XX

XX

XX

XX

XX

XX

XX

XX

modified crops Ltd., etc. Clone

and

Qingdao

Samuels

Industrial

&

transgenic

Commercial Co., Ltd., Beijing Ji Pu Lin

animal

biotechnology Co., Ltd., etc. Zhejiang Qianjiang Biochemical Co.,

Biological

Ltd., Hebei Veyong Bio-Chemical Co.,

pesticide

Ltd.,

Zhejiang

Tonglu

Huifeng

Biochemistry Co., Ltd., etc. Fuhuakang Protection

Tute Co.,

Environmental Ltd.,

Dezhou

Green Bio-fertilizer

Yangguang Biotechnology Co., Ltd.,

biotechnology Shanxi Yian Biological Engineering Co., Ltd., etc. China Animal Husbandry Industry Co., Biological Ltd., QianYuanHao Biological Co., veterinary Ltd., Jinyu Baoling Bio-Pharmaceutical medicine Co., Ltd., etc. Guangdong VTR Bio-tech Co., Ltd., Biological feed

Shandong

additive

Bioengineering Co., Ltd., Novozymes

Yishui

Longda

(Tianjin), etc. Biotechnology Research Institute , Others Zhenxing Group, etc. Source: CCM International

IV-3 Biological pesticide ……………


-

Production

In the past decade, on one hand, Chinese biological pesticide industry has developed rapidly with increasing output, with CAGR of XX% during 2004-2008. On the other hand, biological pesticide market constitutes only about 10% of domestic pesticide market. Since Jan. 1st, 2007, China has banned the use of 5 high-toxic organophosphorus insecticides, namely methamidophos, parathion, parathion-methyl, monocrotophos and phosphamidon, which suggests huge development potential for biological pesticide. The total output of biological pesticide in China was about XX tonnes in 2008, up XX% compared with 2007. Figure IV-3.3 Sales income and profit of biological pesticide industry in China, 2003-2008

Source: CCM International Economic data bulletin

……………. Table IV-3.1.3 Key Chinese manufacturers of avermectins technical, 2009 No.

Company

Capacity 09(t/a)

Output 08(t)

1

Hebei Veyong Bio-Chemical Co., Ltd.

XX

XX

2

XX

XX

XX

3

XX

XX

XX

4

XX

XX

XX

5

XX

XX

XX

Source: CCM International

Future of Green Biotechnology in China  

This report is the unique and latest one available in the world to provide good understanding about Green Biotechnology (GB) in China and to...

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