With execution of the function, two cells are filled. The one on the left is the slope, and the one on the right is the y‐intercept. I manually added the slope and Y‐intercept labels for clarity.
From the y‐intercept, Vmax can be directly determined. The slope can then be used to determine Km.
Vmax is 12.3 mmol/min, and Km is 224 mmol. A graph can be more satisfying than the LINEST function. The graph below shows the data in a Lineweaver‐Burk format. Right click on a data point, select a Format Trend Line..., select a Linear regression and Show Equation, and the graph will display the best‐fit equation for the data points. The slope and y‐intercept should match the output of the LINEST function.