CMHC - Cardiometabolic Chronicle July 2018

Page 24

DIABETES by numbers A healthy lifestyle

Saturated fat

may be more harmful to the

liver

is crucial to

preventing diabetes

and heart disease. A study surveying

3,679 US

adults without diabetes found that

only 3.1%

of participants met the combined recommended diet and physical activity goals.

than unsaturated fat or simple sugars. In a study of

38 overweight people overfed

1000 extra Kcal/day of saturated, unsaturated fats, or simple sugars for 3 weeks, extra calories from saturated fat increased

met the fruit, vegetable, and dairy recommendations.

liver triglyceride content by 55%. Excess unsaturated fats increased this content by 15%, and sugars by 33%. Decreas-

met the physical activity and the weight loss/maintenance goals, respectively.1

3.https://www.ncbi.nlm.nih.gov/pubmed/29844096

21%, 29%, and 13% 37.8% and 58.6%

ing intakes of saturated fat may reduce the risk of non-alcoholic fatty liver.3

1.https://www.ncbi.nlm.nih.gov/pubmed/29500166

A large Korean study showed that

cancer

may increase the risk of

type 2 diabetes. The study included

524,089

men and women with no cancer or diabetes at baseline, followed-up for 7 years.

15,130

participants developed cancer and

26,610

developed type 2 diabetes. Cancer was associated with a

1.35X greater risk

for developing type 2 diabetes. Pancreatic, kidney, and liver cancers were associated with the highest diabetes risk, increasing this risk by

5.15X, 2.06X, and 1.95X.

2

2.https://www.ncbi.nlm.nih.gov/pubmed/29879271

24

www.cardiometabolichealth.org

A recent study published in Diabetes Care shows the staggering economic impacts of diabetes in the US in 2017. The cost of diabetes increased by 26% from 2012-2017, and now costs the US economy $327 billion – including

$237 billion

in direct medical costs and

$90 billion

in lost productivity. Diabetes care accounts for 1 in 4 US healthcare dollars. Diabetics spend an average of $16,7500 in medical care a year, and have medical costs that are

2.3X higher

than non-diabetics.5 Controlling blood glucose, blood pressure, and cholesterol are important for the long-term management of type 2 diabetes. In a retrospective study of 53,120 patients with type 2 diabetes selected from the Veterans Affairs (VA) medical records, achieving treatment goals of

HbA1c <7.0%, LDL-C <100 mg/dL, and BP <140/90 mmHg (triple-goal achievement) was associated with a decreased risk of microvascular and macrovascular complications, and all-cause mortality, with 13,507 patients achieving all three of these targets.4

4.https://www.ncbi.nlm.nih.gov/pubmed/29596940

5.https://www.ncbi.nlm.nih.gov/pubmed/29567642

Food insecurity and living in areas with low physical access to nutritious foods may complicate symptom control in diabetics. A longitudinal study that followed 391 diabetics for a total of 37 months, showed that food insecurity is associated with a 0.6%, or 6.6 mmol/mol higher HbA1c compared to participants that were food secure. Living in an area with low food access was not associated with a change in HbA1c.6 6.https://www.ncbi.nlm.nih.gov/pubmed/29555650


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