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Report from the CRY Centre for Cardiac Pathology (CRY CCP)

Since opening in April 2007 the CRY CCP, the Charity's diagnostic and research laboratory and office, has become well established within the National Heart and Lung Institute at the Royal Brompton Hospital. Research Fellow Sofia De Noronha is running the laboratory very smoothly along the health and safety guidelines established by Imperial College. CRY’s equipment is up to date and working well, making us fully functional and independent of the hospital laboratory. This has led to a significantly reduced turn around time for cases sent to the Centre. Dr Mary Sheppard, who heads the unit, is able to issue her pathology report for coroners and refer pathologists within two weeks, a substantial decrease from the past when it may have taken her up to a month to issue such a report. We have also seen a dramatic 80% increase in the referral pattern. The total number of CRY cases referred in 2007 was 78; from January 2008 to December 2008 the total number of CRY cases referred was 141. The turnaround time of all CRY cases has been kept below 14 days for most of 2007 and 2008, the exceptions occurring when Dr Sheppard has to be out of the office attending conferences or taking annual leave. Our large database of 2000 hearts has resulted in several research projects. Two of these were publications in 2008, nine have been presented as posters at meetings, five have been submitted as papers and four are in preparation. Sharleen Hill, a student under the supervision of Dr Sheppard for her research project, completed her study of sudden cardiac death in young people and was awarded a both a first class honours degree and an award for 'Outstanding student of her year' (2008). Both Sharleen and another student under the supervision by Dr Sheppard, Agata Prowaski, were awarded travel bursaries of £1000 from the British Division of the Academy of Pathology. They presented their research at the US and Canadian Academy of Pathology in March 2009. Our research in the future will emphasise arrhythmogenic right ventricular cardiomyopathy (ARVC), idiopathic left ventricular hypertrophy (ILVH), exercise-related sudden deaths as well as tie in with clinical follow up of families to correlate clinical and genetic diagnoses with pathological diagnoses. Dr Sheppard's secretary, Kathrin Hault, left the Centre in autumn of 8

| CRY Update Issue 48

Top left: the CRY CCP office at Royal Brompton Hospital Top right and middle: Dr Mary Sheppard and Research Fellow Sofia de Noronha Above: Dr Sheppard speaking at the 2008 CRY international Conference in London

2008 to take up medical studies and has been replaced by Jemma Wells who now fulfills the role of Medical Secretary at the centre very efficiently. For more information about the CRY CCP, go to the coroner/pathology section of the CRY website at

CRY Update Magazine - Issue 48  

CRY’s quarterly update magazine with news and information about the charity and our supporters. Registered Charity 1050845.

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