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LIFE SCIENCE IN OULU Company Cataloque 2016

Biotech Ÿ Diagnostics Ÿ Health/Wellness Services Ÿ Health IT Medtech Ÿ Pharmaceuticals Ÿ Other Products and Services

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CONTENTS OuluHealth, At the Heart of Innovation 5 Medical Technologies in Oulu 6 Biotech in Oulu 8 Bioeconomy 10 Food Safety 12 BIOTECH Paras Biopharmaceuticals Finland ValiRx Finland Ltd

49 59

DIAGNOSTICS Focalspec Ltd Ginolis Ltd JouZeNet Consulting Ltd Kide Clinical Systems Ltd Medengine Ltd Medfiles Ltd Mediracer Ltd Otometri Ltd Pedihealth Ltd Screentec Ltd Spektikor Ltd ValiRx Finland Ltd

25 26 35 36 41 42 43 48 50 55 56 59

HEALTH IT 9solutions Ltd Aava Mobile Ltd Aica Ltd Bittium Ltd Eagle Vision Management Ltd Emfit Ltd Fjuul Ltd Grant4com Ltd Haltian Ltd Health Innovation Academy Ltd Kide Clinical Systems Ltd Medanets Ltd Medengine Ltd Nortal Ltd Otometri Ltd Prowellness Ltd Qaamos Ltd Screentec Ltd Tieto Healthcare & Welfare Ltd Usbimed Ltd Valkee Ltd

14 15 17 20 22 23 24 27 28 30 36 40 41 46 48 52 53 55 57 58 60

HEALTH&WELLNESS SERVICES Aava Mobile Ltd Aica Ltd Checkmylevel Ltd Fjuul Ltd Grant4com Ltd Haltian Ltd Happywise Ltd Health Innovation Academy Ltd

15 17 21 24 27 28 29 30

Laturi Ltd Medengine Ltd Medfiles Ltd Otometri Ltd Prowellness Ltd Qlu Ltd Valkee Ltd

37 41 42 48 52 54 60

MEDTECH Emfit Ltd Focalspec Ltd Ginolis Ltd Grant4com Ltd Health Innovation Academy Ltd JouZeNet Consulting Ltd Kide Clinical Systems Ltd Lojer Ltd Medengine Ltd Mediracer Ltd Optomed Ltd Otometri Ltd Pedihealth Ltd Screentec Ltd Spektikor Ltd Usbimed Ltd

23 25 26 27 30 35 36 39 41 43 47 48 50 55 56 58

PHARMACEUTICALS BBS-Bioactive Bone Substitutes Ltd Medengine Ltd Paras Biopharmaceuticals Finland Ltd Pharmatory Ltd ValiRx Finland Ltd

19 41 49 51 59

OTHER PRODUCTS & SERVICES 9solutions Ltd Admescope Ltd Biosilta Ltd Focalspec Ltd Ginolis Ltd Grant4com Ltd Haltian Ltd Happywise Ltd Health Innovation Academy Ltd Horsegenetest Europe Ltd Innokas Medical Ltd Inspector Sec Ltd J. Nuosmaa Ltd JouZeNet Consulting Ltd Lewel Group Finland Ltd Medfiles Ltd MedKit Finland Ltd MeKitec Ltd Pedihealth Ltd Pharmatory Ltd Qaamos Ltd Screentec Ltd Usbimed Ltd

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LIFE SCIENCE IN OULU, Company Cataloque 2016 Executive Publisher BusinessOulu Yrttipellontie 6 FI-90230 OULU, FINLAND Editors Reeta Räisänen, Heidi Tikanmäki, Alpo Merilä, Aaltje Bos, Noora Jansson, Salla Hirvonen, Tero Suutari (BusinessOulu) and companies’ own articles Design & layout Tero Suutari, BusinessOulu

Photography: Studio P.S.V./Reijo Koirikivi Tero Suutari Shutterstock companies’ own photos Translation Monetra Tulkkipalvelu Printed by Erweko, Oulu Published 2016

BusinessOulu Oulu – Capital of Northern Scandinavia – is a growth and development hotspot in Northern Europe. BusinessOulu is in charge of implementing the City of Oulu’s industrial policies and providing growth companies with the services they require, in addition to promoting export, import, investments, and employment. With the help of its international partner network, BusinessOulu acts as a partner to companies and helps them grow, particularly in the North, where it leads and participates in the operations of Suomi-talo (”Finnish Business Hub”). BusinessOulu persistently develops the tourism business, conferences, congresses and events. Oulu’s innovation environment, ecosystems, and think tanks create innovations in a bold and productive manner. The aim is to rapidly develop business opportunities and significantly increase start-up investments. BusinessOulu’s OuluHealth ecosystem is in charge of the Health of the Future scheme, part of the national Innovative Cities (INKA) 2014–2020 program.

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OULU LIFE SCIENCE COMBINES DISCIPLINES FROM HEALTH, BIO, WELLNESS AND FOOD SAFETY SECTORS The life science ecosystem in Oulu is one of the strongest in Finland. It is based on a combination of business- and scientific disciplines dealing with living organism such as human beings, plants or animals in the fields of bio, medicine, health and wellness. The life science sector also links with several different business fields like information- and communications technology (ICT), micro- and nanotechnologies.

There are more than 1,700 life science companies located in Oulu, and from those at least 240 are hi-tech companies. These particular companies address varied global needs and aim to penetrate international markets. Companies also form a central part of OuluHealth ecosystem that the life science sector works closely together with. OuluHealth is one of the five Innovation Alliance ecosystems in Oulu that combines different specialized fields from health, natural sciences, information technology, academic knowhow and business. Oulu life science sector is getting stronger year by year. It is also a field that will be invested in increasingly in the future. This allows life science companies in Oulu, with special expertise and know-how, to grow their businesses and serve their customers even more effectively on domestic and global markets. Best regards, Heidi Tikanm채ki Key Account Director, Life Science BusinessOulu +358 40 542 0007 heidi.tikanmaki@businessoulu.com

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OULUHEALTH, AT THE HEART OF INNOVATION OuluHealth is a network of experts representing health, medical/natural sciences, information and other technologies, academic know-how and business all focusing on one goal: to create an innovative health environment and to deliver sustainable services to customers and health companies in the region. While health care is often referred to as a singular entity, it is, actually, a patchwork of organizations, businesses, hospitals, research institutes and disease specific clinics, each with their own priorities and benefits. The problem of fragmentation in our health care system, i.e. the patients often going from nurse to doctor, from doctor to laboratory, from laboratory to specialist and then to therapist is the root cause for of the skyrocketing costs of medical services. Despite the good intentions of government, health care workers and service providers, there´s often limited interaction between these different actors, leaving patients to find their way through unclear care pathways. THE NEED FOR AN ECOSYSTEM Providing the highest level of care requires that care professionals engage with the patient, work together and interact in a meaningful way in an environment that supports personalized care. OuluHealth works towards this innovative environment by facilitating cooperation between health providers such as Oulu University Hospital, research institutes, scientists, industry partners, technology stakeholders, and the City of Oulu. INDIVIDUALIZED CONNECTED HEALTH Like many other cities around the world, Oulu is adopting information technology as a way to access and share information, to enlarge health care resources and to provide increased, flexible opportunities for patients and doctors to communicate and deliver care. This means, for instance, that people can choose when, where and what kind of technology they need in order to connect with their doctor. Prescription, feed-back, and test results will be delivered electronically, irrespective of time and place and patients can decide with whom they like to share the result of a check-up. In plain language, people will become more responsible for their own health. A REALISTIC TESTING PLATFORM The Oulu University Hospital has opened a living lab environment that enables and supports the development of health and medical technology products and services in a user-oriented way. For health care professionals in particular, the living lab facilitates multi-disciplinary innovation workshops and rapid prototyping. The facilities can be converted into various test scenarios such as an operation

theatre, a ward or delivery room where professionals can test the latest medical technology solutions on the first floor of the Oulu University Hospital. DIGITAL ECOSYSTEM FOR BIO BANKS The Northern Finland Biobank Borealis will create a new digital ecosystem for national biobanks. Digital data will facilitate biobank research and diagnostics by enabling researchers to study high-resolution images instead of tissue samples. In addition to this, The Northern Finland Biobank will offer the research community access to professionallymaintained sample collections. These are linked to clinical health information and accumulating research data as well as sample storage, management and data mining infrastructures. The biobank is owned by a federation of municipalities of Northern Ostrobothnia’s hospital district (PPSHP). CONTACTS

Noora Jansson Director OuluHealth, BusinessOulu +358 40 753 2917 noora.jansson@businessoulu.com

Salla Hirvonen Specialist OuluHealth, BusinessOulu +358 40 726 1842 salla.hirvonen@businessoulu.com

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MEDICAL TECHNOLOGIES IN OULU Finland’s northern city of Oulu is becoming a widely recognized leader in the emergent field of medical technology, which combines life sciences and medicine with different aspects of engineering. As the population ages and the desire to take control of one’s own health grows, so grows the need for novel, affordable technologies that provide instruments for measuring health. The development of such technologies lies at the intersection of engineering, medicine and natural sciences, which is exactly where the competitive advantage of Oulu lies.

Oulu’s medtech ecosystem is a multifaceted network consisting of the university, public organizations like the Oulu University Hospital and the VTT Technical Research Centre, and various medtech companies and services providing R&D to companies and manufacturers. Two of the University of Oulu’s main research focus areas, biosciences & health and information and communications technology (ICT), are being combined in the university’s research projects. Indeed, a good deal of health-related innovation in Oulu stems from university research. Some of these scientists and designers have achieved massive global success, such as Polar Electro. Although not directly related to medical technologies, Codenomicon, an Oulubased company that also has its roots in the university research, was recently chosen by the US Food and Drug Administration to provide solutions for fuzz-testing medical devices and software. VTT Technical Research Center of Finland conducts research in fields that integrate ICT and printable electronics. It collaborates closely with other players in the medical technology field. Oulu’s world-class engineering expertise has already been put to use to solve health-related questions. Innokas Medical, for example, designs and manufactures medical equipment for the world’s leading medtech companies. Another example is Ginolis Ltd, a manufacturer of diagnostic disposables and tools, which utilizes the automated technologies derived from the mobile phone industry.

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These companies that represent the health ecosystem of Oulu greatly benefit from the city’s collaborative atmosphere as well as the unrivalled level of innovation and intelligence among the workforce. The combination of engineering know-how and medical expertise in the Oulu region make it a perfect environment for innovative companies aiming to be the next big thing in the booming market of medical technologies. Many of Oulu’s medical technology companies are startups, but have potential to evolve into global players and large-scale employers, both in the R&D and manufacturing areas.


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BIOTECH IN OULU In addition to medical device technology and information and communications technology (ICT), Oulu has a reputation as one of the most intelligent and innovative cities in the world. This is due to the novel work being done in the city’s biotech labs and businesses. Among them, there’s the world’s first production method for recombinant collagen, world-class production technologies for biopharmaceuticals, and drug discovery based on cutting-edge research related to connective tissue and hypoxia, to name a few.

Oulu’s particular blend of modern biotech has its roots in academic research. A leader coordinating and supporting cutting-edge biotech research in the area is unquestionably Biocenter Oulu. Founded in 1986 within the University of Oulu, Biocenter Oulu is the first biocenter founded in Finland, and serves as a multi-disciplinary umbrella organization. It gathers together the strongest assets of Oulu’s biotech and health related research, which is one of the university’s main focus areas in research. Such excellence has not been unnoticed by the business world. One of the most successful biotech companies currently benefiting from this research is a US-based biotechnology company FibroGen, which focuses on the development therapeutics. The company started collaborating with the University of Oulu back in 1994, when it was searching for a partnering research group with specialized know-how on collagen research. Oulu’s excellence in protein research and production also expands beyond extracellular matrix proteins. This highclass protein research provides biotech companies in the Oulu region with strong expertise in many traditional biotech areas, including bioprocessing and recombinant protein production.

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One example is Paras Biopharmaceuticals, the winner of 2014 Frost & Sullivan Biopharmaceuticals Technology Innovation Leadership Award. It is a biotechnology company developing optimized manufacturing technologies for protein and peptide drugs. It has developed some of its protein production technologies in collaboration with the university research, and works collaboratively with several protein research groups. In addition, the patented recombinant protein production technology utilized by Biosilta, a company concentrating on large-scale biomolecule protection, was originally developed at Biocenter Oulu. Because the work being done in modern biotech is increasingly more dependent on technology, the biotech field in Oulu also hugely benefits from the wide engineering expertise in the region. And while biotech companies and research units based in Oulu are varied in their focus and scale, they are equal in their level of innovation and ambition. With the city’s wide array of research institutions and resources, Oulu is quickly becoming the ideal location for biotech companies seeking to develop and commercialize new concepts.  


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BIOECONOMY Oulu has been recognized for its strengths in especially biosciences and biotechnology, information technology (especially wireless technology) as well as other technologies related to these (for example censors and AI, effective bio-production technologies and cleaning and characterization technologies of bio-products). All these competencies are developing at a fast pace. Tailor-made proteins, enzymes and genetic circuits are being planned, built and utilized, and biological devices and production systems (cells) are being installed in a controlled manner. New competencies lead to new products and solutions in bioeconomy. They, in turn, open new business opportunities. In addition, they promote sustainable development by, for example, replacing oil and solvent-based products.

The approach is wide ranging from biological and biomedical research to modelling, computer-aided planning, process technology, chemical synthesis and material physics. Bio-economic products are versatile: they can be either of biomass origin or produced. They also represent different levels of the value pyramid. Innovations and technological competence are amongst the key elements to success in Oulu. Therefore, the emphasis will lie on the top levels of the pyramid. This is also reflected in the goal of LifeScience in Oulu, which is to create new

economic growth and new jobs in bioeconomy through added-value products and services and by developing related technology. Oulu LifeScience is focused on 1. added-value products and services and technologies related to these 2. products and solutions with a global base and good market opportunities 3. exploiting the full potential of the region

PHARMACEUTICALS COSMETICS UNIT PRICE

• NEW EXPERTISE • INVESTMENTS • GLOBAL NETWORKING • R&D • NNOVATIONS

BIOMATERIALS

BIOCHEMICALS

BIOFUELS

BIOENERGY - HEAT & ELECTRICITY QUANTITY HIGHER PULP AND PAPER

Figure: Ministry of Employmend and the economy: Report 06/2011 ”Biotalous nousuun” (Increasing the bio-economy).

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• • •

PRICE COMPETITION COMPETITIVE STRUCTURES AND OPERATIONAL MODELS


BUSINESS AREA:

Health IT | Health/Wellnes services | Diagnostics | Medtech | Pharmaceuticals | Biotech | Other products and services

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FOOD SAFETY Global trends – such as an increased export of food, the mobility of consumers and an increase in large-scale processed and convenience food consumption – contribute to risks related to food safety. Authorities are devoted to increasing the quality and safety requirements. Consumers are also keen on getting more information on food safety. This increases the need for self-monitoring of foreign objects and substances in the food industry.

Therefore, we need to develop different methods and devices so that we can 1) detect challenging foreign objects, for example glass or bone chips, in food casings, 2) identify foodborne pathogens already at an early stage of the food production process. By using new methods with a rapid identification we can identify for example listeria monocytogenes already a few days earlier than normally. 3) There is also a need to identify chemical contamination (for example toxins). The traceability of raw materials and products as well as remote diagnostic and quick diagnostic products and cloud service and analytics are also subject to increased interest. Food Safety Cluster is a well-equipped food safety laboratory based in Oulu offering technology companies and food companies a platform for testing and development, and research partners for developing competence, products, services and solutions in the food industry. This gives us a possibility to meet the growing needs of the food safety and food processing industry.

At present, North America is the main market for food safety testing. Asia-Pacific is expected, however, to be the fastest-growing market during this decade. New regulations support the growth of food safety testing. For instance, Implementation of Food Safety Modernization Act (FSMA) in the U. S. and an extended food safety action plan implemented in China are projected to drive the growth of the food safety testing. By 2019, Food Safety Testing Market is estimated to be worth $15 Billion (marketsandmarkets. com, January 2015).

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HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

9SOLUTIONS LTD Unique solution for healthcare safety and productivity. 9Solutions is a manufacturer of modern healthcare safety and productivity solutions for hospitals, care homes, and home care environments. 9Solutions provides unique customer benefits by combining real time situational awareness, healthcare safety solutions, and workflow optimization intelligence integrated in a single solid system. 9Solutions systems are used globally in improving the productivity and safety of healthcare professionals, residents and patients.

PRODUCTS / SERVICES 9Solutions Integrated Positioning and Communication System (IPCS) is based on Bluetooth® Low Energy and Cloud Technologies covering following application requirements in one solid system: A Personal Alarm system for staff, a Nurse Call system for patients and residents, care phones and GPS trackers for home environment, and smart phone application to connect professionals and families. All solutions utilize the 9Solutions real-time locating technology platform. Home Care An up-to-date snapshot of the daily life of an elderly person for professionals and relatives • Tracking safety bracelet, smart exit detector and care phone • Background system for upkeep and management • Smart phone application for staff and relatives Assisted Living The system keeps the staff up-to-date about important events and tasks. • Location of residents at room-level accuracy • Advanced exit monitoring: bed, apartment, area, property • Wireless tracking safety bracelets • Wireless, fixed call buttons and pull cords Healthcare Centres and Hospitals One connected system solves the safety and location information needs. The infrastructure required is integrated into the corridor dome lights. Nothing else is needed.

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• Location information on people and devices • Nurse call • Personal safety • Automatic alerts on the basis of the location • Monitoring of the activity level of the client being sent home and safety alerts • Open interfaces Competitive advantage: • One for all. Only a single connected solution is needed for home care, assisted living, healthcare centres and hospitals. • Wireless, SaaS-based solution is easy to install: Deployment time of the 9Solutions system is typically 1/3 comparedto competing solutions. Easy installation guarantees highly competitive investment cost. • Predictable life cycle costs: Advanced Software as a Service (SaaS), 24/7 free support, and robust standardized technology ensure 100% transparent maintenance costs. • Decision-making is speeded up and decisions are based on real facts thanks to the real- time situational information and automated reporting. Your reliable partner. Globally 400 care home & hospital deployments, European-wide cooperative partner network. Market leader in care home solutions. Market share approx. 25 %.

� Offices: Oulu (HQ) & Helsinki Staff: 25 Our roots are in the resolute Finnish wireless technology industry. Our mission is to utilize the solid foundation to improve and enhance safety and productivity of the healthcare sector. CONTACTS 9Solutions Ltd Teknologiantie 2, 90590 Oulu +358 20 752 9050 sales@9Solutions.fi www.9Solutions.com


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

AAVA MOBILE LTD Aava Mobile, located in Oulu, has quickly become the biggest ODM in Europe for mobile devices. In 2009, Aava Mobile was founded with a focus on open OS smartphones and handhelds. The Company name, Aava Mobile (Aava is Finnish for “open”), represents this product philosophy. In recent years, Aava Mobile has introduced its smartphone skills on the purpose-build tablet and handheld market. Currently, Aava Mobile offers tablets and handhelds for semi-professional and professional markets.The offering includes customer-specific tablet and handheld developments as well Aava roadmap products for various vertical markets. Aava Mobile works with its partners and customers to address their specific needs for vertical market devices.

PRODUCTS FOR HEALTHCARE • Ruggedized tablets and handheld devices • SmartBox – compact PC computer for smart devices or light computer replacement • Custom HW designs INARI: The water-proof, shock-proof and dust-proof housing (IP65) withstands the requirements of healthcare, retail, construction, military and other harsh environments without the extra bulk or weight of a ruggedized case. Chemically resistant IP65 mechanics makes Inari perfect for healthcare implementation resistance up to 1.8m. • Ruggedized & Waterproof • One-hand Design • Intel Platform x86 • Digital Pen • Easy Customization • Removable Battery • Longevity 4 years availability

REFERENCES Apart from delivering our roadmap products and accessories to the medical customers we also develop customized purpose-built devices from concept to final production, fast and affordable. We license our platforms, we develop customized products based on the latest mobile chipsets, screen sizes, radio/antenna specifications, certification requirements, and manufacturing techniques. We take care of the full process, from requirements specification to industrialization and manufacturing. We treat your IP with extreme care, and our approach offers significantly reduced costs and time-to-market.

� CONTACT Our headquarters: Aava Mobile Oy Nahkatehtaankatu 2 FI-90130 Oulu, Finland Tel.: +358 8 373 800 Fax: +358 8 373 811 info.fi@aavamobile.com Our subsidiary: Aava Mobile GmbH Christoph-ProbstWeg 420251 Hamburg, Germany Tel.: +49 40 61135-425 Fax: +49 40 61135-426 info.de@aavamobile.com www.aavamobile.com

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HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

ADMESCOPE LTD Admescope is a preclinical contract research organization (CRO) providing the pharmaceutical, biotechnology and veterinary industry with premium quality tailormade services to drug discovery in the area of ADME-Tox.

SPECIAL KNOW-HOW The service offering is widely spread over the whole ADME-Tox area, from highly tailored studies to High Throughput Screening (HTS). Our unique expertise lies in in vitro & in vivo drug metabolism, drug-drug interactions, pharmacokinetics and quantitative bioanalysis. The right study set-up can always be found whether in the discovery or lead optimization phase. The state-of-art quality data is ensured by optimizing the conditions according to the compounds’ characteristics instead of using generic protocols. All data can be interpreted for the customer so that (s)he understands the real meaning of the numericalvalues and observations. Our team of experts consists of chemists, biochemists, pharmacologists and technicians, all with a long experience and a strong

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expertise in ADME-studies. The combination of our expertise and top quality instrumentation enables us to deliver high scientific and technical quality, always on time. PRODUCTS / SERVICES We provide customers with high-quality problem solving intelligence in: • In vitro Metabolism • In vivo DMPK • Drug Interactions • Quantitative Bioanalysis • Permeability and Transporters • Physicochemistry and Binding • In vitro Toxicology • HTS ADME REFERENCES Currently, we serve customers on four continents and in 20 different countries. Our team has also participated in publishing more than 100 peer-reviewed scientific papers.

� Head offices: Oulu, Finland Size: 16 employees Established 2011 CONTACTS Admescope Ltd Typpitie 1 90620 Oulu, Finland www.admescope.com info@admescope.com Tel: +358 (0)207 429 970


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

AICA LTD Aica was founded by young and enthusiastic entrepreneurs with a huge vision: www.tohtorille.fi will be the number one service for Finns when they book their HealthCare Appointments. The company’s mission is clear: Aica wants to revolutionize the online booking, by building a unique meeting place for patients and health care professionals.

SPECIAL KNOW HOW In Aica, we have deep and comprehensive know-how about the business potential and the value chain of health care sector, especially from the customer acquisition point of view. We are focused on online booking and digital marketing. Aica has developed Tohtorille.fi environment, where patients can independently find the best health care professional, book an appointment, compare prices and evaluate the treatment. PRODUCTS/SERVICES The website Tohtorille.fi was founded in 2013. The aim is to improve availability and patient orientation of health care services. For patients, it offers a safe, smart and easy 24/7 way to book an appointment. Tohtorille.fi is a meeting place where professionals inform about available appointments to be booked by patients. This is how the location, time, and caring professional can easily be selected by the customer. Tohtorille.fi is free-of-charge for patients. Finding the next available appointment means that it is possible get to a treatment the same day.

The health care professionals registered in Tohtorille.fi are leading professionals in Finland offering high-quality and readily available treatment in order to fulfill the requirements of patients in the digital era. The service helps professionals to have more patients, to handle the bookings smoother and to inform about their specialities (or attach a CV)

� Staff number 7 CONTACT Aica Ltd. Miikka Hätälä Torikatu 23, 90230 Oulu 045 2003711 miikka.hatala@tohtorille.fi www.tohtorille.fi

MAJOR ACKNOWLEDGEMENTS • One of the seven companies that enrolled in Oulu Business Accelerator program in 2013 among many significant gazelle companies • Three angel investors • Participating in TEKES – Ideat kiertoon REFERENCES Tohtorille.fi is a leading online booking environment in Finland. Nearly half of all private dentists in Oulu and totally around 400 health care professionals have chosen Tohtorille.fi as their online booking equipment. (See the full list of references in Tohtorille.fi) More than 2,000 patients have booked their health care via Tohtorille.fi.

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BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

BIOSILTA LTD BioSilta is a privately-held, entrepreneurial company that utilizes the company’s proprietary EnBase technology platform to develop innovative EnPresso reagent-based microbial growth systems that significantly increase yields of high quality biomolecules when compared to conventional growth media.

SPECIAL KNOW HOW EnBase technology is a key element within every EnPresso growth system, offering a novel approach to control the feeding of microbial cultures. A glucose-releasing agent breaks down long chains of polysaccharides releasing glucose units to feed the microbial culture. Controlling glucose release (the ‘feed’) controls the rate of growth, microbes remain in linear growth. PRODUCTS/SERVICES EnPresso growth systems revolutionize the role of microbial cell culture in the lab – solving the well-recognized problems of low yield and poor quality – making it easier than ever for scientists to focus on their research and deliver high-quality results. Together with standard laboratory equipment, simple-to-use EnPresso tablets have the power to increase the yield and quality of a recombinant protein. MAJOR ACKNOWLEDGEMENTS Enpresso Growth systems reduce hands-on time, improve reproducibility • Cultures ready to induce the next morning • EnPresso tablets dissolve into sterile water - no media autoclaving • Optimized protocols ensure controlled growth and metabolism in shake flasks or 24 deepwell plates Save media and time • No need to change media, temperature, pH or induction conditions • No OD measurements to determine exact moment for induction • Smaller volumes to centrifuge, harvest and purify

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REFERENCES Customer feedback • Significantly reduced labor in downstream processing with smaller volumes and fewer shake flasks. • Greatly improved yield and reproducibility, saved costs by reducing IPTG consumption

� Founded in 2007, BioSilta is a privatelyheld, entrepreneurial company that utilizes its unique, proprietary EnBase® technology, bringing in-depth knowledge and experience from the world of large scale biomolecule production into the research laboratory. BioSilta is a spin-out company of the Bioprocess Engineering Laboratory at the University of Oulu, currently supported by the investment companies Omega Funds, Inveni Capital and Oulun Seudun Hyvinvointirahasto. The company comprises a multi-national group. Offices: Cambridge (headquarters), Oulu and Berlin Staff: 7 CONTACT BioSilta Ltd P.O. BOX 5000 90014 University of Oulu Tel +358 44 557 1865 info@biosilta.com www.biosilta.com


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HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

BBS-BIOACTIVE BONE SUBSTITUTES LTD BBS-Bioactive Bone Substitutes (BBS) is a biomedical technology company developing innovative next generation, biologically active medical device implants to be used in orthopedic surgery. BBS has its production facilities in Reisjärvi. In September 2015, BBS receivedan authorization for manufacturing medicinal substance from FIMEA.

SPECIAL KNOW HOW BBS’s core competence is in R&D and manufacturing next generation bone substitute implants. Currently, the development status is in clinical trials. BBS will initially enter foot and ankle area and at a later stage expand to other indications as spinal fusions. PRODUCTS/SERVICES Pastes form bone substitute implant to be used in bone healing problems. The implant is based on reindeer none protein extract containing the whole spectrum of natural bone growth factors and proteins. The combination of the extract and optimised scaffold material is the solution of BBS for an ideal bone substitute to be used in key indication areas as an osteoconductive/ osteoinductive bone void filler. The Products are aimed at orthopaedic, trauma dental, maxillofacial and veterinary indications. The trade name is ARTEBONE®.

MAJOR ACKNOWLEDGEMENTS • Outstanding performance at a moderate price. • Extremely safe, no human disease transmission • Easy and ready to use syringe • Reduces operating time and costs • Excellent batch-to-batch consistency • A natural product of a new generation • Renewable raw material

� CONTACT BBS-Bioactive Bone Substitutes Oy info@bbs-artebone.fi www.bbs-artebone.fi Phone: +358 207 924 700

REFERENCES BBS is globally well-connected with orthobiologic companies. The CEO Pekka Jalovaara (MD, PhD, Professor of Orthopaedic Surgery) is internationally highly recognized expert in the field of bone healing. The patent portfolio is comprehensive, more details on www.bbs-artebone.fi.

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BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

BITTIUM Bittium develops advanced technology and transforms it into enriching end user experiences. Bittium specializes in demanding embedded software and hardware solutions for the automotive industry and wireless technologies.

SPECIAL KNOW-HOW Bittium specializes in developing reliable, secure communications and connectivity solutions using the latest technologies and its expertise in wireless system design. Bittium provides innovative products and customized solutions based on its product platforms, and R&D services for customers in various industries. Bittium also offers high-quality information security solutions for mobile devices and portable computers. PRODUCTS & SERVICES For the health care and wellness companies Bittium offers • Secure and easy-to-use remote access solutions for mobile care workers • Connected wearable devices and connectivity gateway platforms, reference devices and design services • Cloud based design services • Applications e.g. iOS, Android • System integration services MAJOR ACKNOWLEDGEMENTS • The Bittium Wearable Platform was utilized in Adidas miCoach SMART RUN launched in 2013. • Enterprise smart watch reference design was launched in October 6 at Internet of Things World Europe 2015 conference

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REFERENCES During the past years, Bittium has contributed to numerous wireless wellness and health product development programs. We have helped our customers to bring products swiftly to market, solved challenging technology implementations and integrations, and developed products all the way to mass market quality. In addition, we have worked with several health care districts in Finland and NHS Trusts in UK to allow mobile care workers easy and secure access to their office and clinical tools wherever they are, helping them to save time and thus improve patient care. Our customer relations are confidential; we are a partner you can trust.

� Bittium is headquartered in Oulu, Finland, with additional offices in Kajaani, Tampere and Espoo. Other locations: USA, UK and Singapore. In total, we have about 500 employees. Company net sales: €52.7M in 2014. The company was established in 1985. CONTACT Sami Toljamo Tutkijantie 8, 90590 Oulu, Finland +358 40 344 3805 sami.toljamo@bittium.com www.bittium.com


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

CHECKMYLEVEL LTD Checkmylevel is a fitness technology company with an intelligent solution for professional and recreational athletes to exercise for maximum impact.

SPECIAL KNOW HOW Checkmylevel has specialized in neuromuscular body assessment. The methodology is based on the ability of the peripheral nervous system to carry impulses, which is especially important in sports that require speed, strength, skill and coordination. The result reveals the bodily state faster and more accurately than measurements based on heart rate variability (HRV). PRODUCTS/SERVICES Checkmylevel is the fastest, most accurate and truly real-time solution for the assessment of recovery monitoring and training readiness. It assesses the recovery level of muscles by using a portable assessment device and a mobile app. The 30 second assessment of muscular and nervous readiness before training guides you to keep going, train harder, or slow down to recover.

The Checkmylevel assessment is based on personal baseline, not on nominal values. Therefore, it is the most accurate method for recovery analysis. The assessment is recommended every day but can also be used from time to time depending on your personal training schedule. MAJOR ACKNOWLEDGEMENTS • Vuoden Liikuntatuote (Sports Product of the Year) Finalist 2013 • Sports Technology Award Finalist 2013 REFERENCES Many world-class individual athletes, e.g. World Champions, use Checkmylevel. Also, a number elite teams from NBA, NFL and NHL as well as top-European football and ice hockey players are among happy customers.

� Offices: Oulu (HQ), Espoo, Finland Size: 5 full-time 2008 * The history of the company dates back to early 2000s when the first adaptation of the method and technology was introduced by a physiotherapist. Years later, the first product was released for professional users. The current Checkmylevel solution is aimed at both professional and recreational users. *Development of Checkmylevel started in 2011 CONTACT Minna Saloranta, Co-Founder Elektroniikkatie 3, 90590 Oulu +358 40 5646498 minna.saloranta@checkmylevel.com www.checkmylevel.com

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BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

EAGLE VISION MANAGEMENT LTD Eagle Vision Management Ltd, founded in 2013, provides management solutions optimizing daily workload in healthcare and technology sector. We are an active partner and co-operate with different institutions within education, research and science along with other companies..

SPECIAL KNOW HOW • Multiple companies in different industries are not able to exploit the massive amount of data their processes generate • New technologies are in place to measure the use of resources, e.g. consumption in energy sector, and use of resources in health care, but the raw data is seldom refined into any analysis, and following actions. • Companies have stated the need for benefiting of this data mine. • We provide management solutions for observing, orienting, and making decisions to enable optimal actions for increased profitability. PRODUCTS & SERVICES Situational awareness solution Tilannekuva for companies in different industries. Tilannekuva (Situational Awareness interface) Easy-to-use interface for management,

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enabling up-to-date view of the situation of the company, and various ongoing processes. The desired data is collected from different sources, e.g. sensor and information systems. After analyzing the data, TIKE produces desired information for the management. Turvapallo™ Based on real-time information which enables proactive reaction to possible disorders. The system will use different information from sensor and information systems for automated status updates and alarms, which enable preventive actions. REFERENCES Currently, Tilannekuva is used in medical technology development, elderly care and energy sector.

� CONTACT Eagle Vision Management Ltd. Ollilantie 4 90440 KEMPELE, FINLAND Robert Huuhilo robert.huuhiloeaglevision.fi +358 40 544 7427 www.eaglevision.fi


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

EMFIT LTD People want to improve their health and keep fit, but to keep the motivation, the measuring and tracking of physical training and recovery as well as stress and sleep quality should be fully automatic and worry free.

OUR SOLUTION Emfit QS is the first non-contact heart-rate variability enabled sleep monitor. HRV is the best indicator of training recovery and stress level. It also provides essential sleep data including the REM and deep sleep, heart and breathing rates, turn & toss, even snoring. Because it is necessary for the recovery of your brain to get enough of REM sleep, and for the recovery of your body to get enough deep sleep, our product has a true 3-stage sleep classification (REM, Deep, Light). Emfit QS consists of a thin, flexible and durable under mattress bed sensor and small electronics with embedded Wi-Fi or cellular data module. User-friendly web application enables customers to access the data from our server with a browser. It is non-contact, always on, and uses mobile optimized web application instead of a phone app that has to be turned on every night.

product that does all that the customer needs: heartrate-variability (HRV), all sleep classes, heart and breathing rate, and movement activity through all night. This is why Emfit QS is the best device helping customers to keep track of their recovery, and stress and sleep quality. Its proprietary and patented sensor technology is backed up by hundreds of nonbiased publications. Business Model: Our business model is selling hardware and online data service. The pricing is incremental, starting with no monthly fee. The business model includes OEM-type, private label and own brand sales.

� MISSION We help customers to keep track of their daily recovery, and stress and sleep quality without needing to wear a device or trying to remember to turn the equipment ON AND OFF COMPANY PROFILE URL: www.emfit.com Industry: Electro-active sensors and sensory solutions Founded: 1990 Locations: Finland, USA Staff: total 17 situated in Finland, Germany, USA, Canada, and China. CONTACT PERSON: CEO Heikki Raisanen Phone: +358-500-678767 heikki.raisanen@emfit.com Twitter: @heikkiraisanen

TARGET MARKET Although our product is non-wearable, we consider ourselves as part of the wearable market where medical, fitness and wellness merge. The wearable market is expected to grow five-fold in the next four years, from 2,7 billion USD to 13 billion USD. Our product is targeted at athletes, corporate wellbeing and self-tracking. COMPETITION AND OUR COMPETITIVE ADVANTAGE There are other non-contact sleep monitors from Withings, BAM Labs and Beddit on the market. There are wearable devices from Basis, Fitbit and Jawbone that now count even heart rate and REM sleep. But there is no other

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BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

FJUUL LTD Fjuul is a mobile app that turns everyday activities into meaningful exercise. It provides guidance for changing daily behavior and building healthy routines to feel energized and keep in shape.

OUR SOLUTION Unlike most of the existing apps and gadgets, the Fjuul technology has a strong scientific foundation. It translates daily, casual movement into a new measurement unit called Fjuul Points – a universal “currency” of healthy activities. They measure the intensity of movements and related energy consumption (in medical units called METs). Instead of just counting the steps one takes, with Fjuul users can realize the difference of the daily choices they make, such as taking the stairs instead of using the elevator – they can now learn how the mix of intensities impact their exercise levels. This makes an excellent platform for bringing more value to the millions of mainstream users. We also provide a turnkey SaaS solution to new and existing business customers to enter the wellness space.

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� CONTACT Simo Pahkamaa, COO simo@fjuul.com +358 45 8448863 www.fjuul.com


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

FOCALSPEC LTD FocalSpec is a privately-held Finnish high tech company offering laboratory level topographic imaging for online quality control and process optimization. Our product range consists of sensors, profilers and scanners for metal, electronics, plastics and medical industries and systems integrators.

SPECIAL KNOW HOW Our innovation is built on line confocal imaging (LCI) ensuring the most accurate measurement results without the limitations of the traditional measurement methods. Our technology works even on the most challenging surfaces such as dark matte, glossy and transparent surfaces. There is no speckle noise nor interference and a submicron measurement accuracy is guaranteed be the samples moving or not. The automated optical testing procedure is free of any physical contact.

REFERENCES FocalSpec is working with the industry leading companies, who require extreme measurement precision and repeatability in their FA testing or DFM guidelines, have thin components or otherwise challenging surfaces (transparent or glossy) to analyze.

� MISSION FocalSpec is a VTT (Technical Research Center of Finland Ltd) spin-off founded in 2009. There are 15 professionals working at the headquarters in Oulu, Finland. We operate globally through a skilled sales network and partners. CONTACT PERSON: FocalSpec Ltd./ Business Development Director, Heimo Keränen Kaitoväylä 1, 90590 Oulu, Finland +358 10 231 2810 info@focalspec.com www.focalspec.com

PRODUCTS/SERVICES Our product range consists of scanners, profilers and sensors: • FocalSpec 3D Scanner for at-line factory acceptance testing of circuit boards in electronics industry • FocalSpec Edge Profilers (EP) for slitting process QC in metal industry • FocalSpec Seal Profilers (SP) for seal integrity inspection in plastics and medical industries • FocalSpec MicroProfilers (MP) for measuring surface roughness of moving webs, cables, tubing and extrudates online • FocalSpec LCI Sensors for systems developers and integrators

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BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

GINOLIS LTD Ginolis specializes in developing and providing cost-efficient, disposable test platforms combined with automatic manufacturing solutions for the global diagnostic and medtech industries.

The global diagnostic industry is beginning a transition towards automated production and digitalized services, and Ginolis wants to be one of the leading global systems suppliers to enable that shift. Ginolis solutions are characterized by high precision, modularity and an ability to handle fluids in nano-scale. AUTOMATION Ginolis’s compact, modular automation solutions are based on our patented technology, which facilitate the combination of flexibility and precision required for diagnostics production. We offer automated production systems for the manufacture of diagnostic disposables, as well as automated laboratory workflow solutions.

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DIAGNOSTIC DISPOSABLES Ginolis also develops and provides disposable test platforms. We are experienced in various microstructures including microfluidics, microspikes and micropillars. Our proven and highly efficient platform development process takes you from concept to full-scale production. In addition, we offer original design manufacturing proposals based on our patented precision and fluid dispensing technology. Our facilities are ISO 13485 certified. REFERENCES We are privileged to work in co-operation with many of the world’s leading diagnostic companies. For more information, please visit ginolis.com.

� Established in 2010, Ginolis is privately owned and headquartered in Oulu, Finland with subsidiaries in Uppsala, Sweden and San Diego, USA.. COMPANY PROFILE Ginolis Ltd. Automaatiotie 1 tel. +358 (0) 8 819 2200 90460 Oulunsalo Finland info@ginolis.com www.ginolis.com CONTACT Mr. Markku Känsäkoski VP, Technology Innovation tel. +358 40 545 0903 E-mail: markku.kansakoski@ginolis.com


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

GRANT4COM LTD Grant4Com’s testing and certification services contribute to product, technology, service or module development enabling fast fact-based decision-making and timely sales with high quality making sure that customers are delighted by your solutions!

PRODUCTS/SERVICES Overall product and service quality assurance including: • Audio verifications • Bluetooth tests and certifications • Requlatory certifications and market access services (CE, FCC, GCF, PTCRB etc.) • Mechanical and material reliability • Failure analysis • EMC, ESD, SAR measurements • Operator/Country approvals • Production quality assurance • User testing • Field testing • M2M • EM/PM measurements • Design corrective activities

� Head office: Yrttipellontie 6 90230, Oulu Side office: Elektroniikkatie 10 90590, Oulu Size: 10-15, revenue 1m+ Establishment 2008 Has acquired Nokia’s world-class test capabilities to enable Oulu area growth. CONTACT DETAILS Janne Siltari Yrttipellontie 6, 90230, Oulu +358405170196 janne.siltari@grant4com.fi www.grant4com.fi

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BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

HALTIAN LTD Haltian is a visionary engineering house, established in 2012. We design, develop and give life to high-technology electronics, ranging from miniaturized wearables combined with sensors and radio technology to high quality software, all incorporated in a beautiful user experience. We focus on new challenges by bringing mobile technologies to new frontiers, creatively realizing any mobile and sensor technology need. You can find everything you need to design and execute under the same roof. Owned by its workers, we are the fastest growing company in Northern Finland with a current headcount of around 80 world class mobile technology professionals.

SPECIAL KNOW-HOW Besides the courage to do something for the first time in the world, new innovations require a fact-based design, the right choice of hardware, and technology that makes the experience come to life. With us, you get all design, software, hardware, testing, certification and productization services from a single source, with a single project management. This ensures the creation of premium user experience, quality end products and services. We are experts at making almost any idea into a product. We can start the design and development work from a blank slate and turn it into a wireless device that can be mass produced with bigger or smaller volumes PRODUCTS/SERVICES “We make your vision define tomorrow!” We are actively involved in research projects with universities and the health care industry to find affordable and continuous methods of measuring human health and well-being. We keep up with the latest development in the field, and we know that with the right choice of components and expertise we can create new, exciting and innovative solutions for life science and really make a difference in people’s lives.

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Smaller device components and the development in primary construction of mechanics and production technologies make it possible to get the same performance with less required space and size. Our HW teams know how to create an optimal HW integration with a functional embedded SW for a unique wearable product that really stands out with its performance, usability and looks. This is how we can go from portable health care products to wearable ones and beyond. REFERENCES Please see our references on our web page: www.haltian.com.

� Headquartered in Oulu, another location in Silicon Valley. Employs around 80 professionals with an average of 15 years of experience in mobile electronics. The revenue for the second year of operation (2014) was over €7M. CONTACT Haltian Ltd Yrttipellontie 1D 90230 Oulu, Finland +358 (0) 10 322 3400 www.haltian.com


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

HAPPYWISE LTD HappyWise is an expert in e-learning and serious games. Our aim is to change the way the health care sector educates their staff and patients. E-learning and gamified solutions can decrease costs and at the same time intensify the learning experience, making the it fun and motivating.

SPECIAL KNOW-HOW We at HappyWise want to make learning and education fun and effective. Our special knowledge is in gamification, games and e-learning. Our company provides the full package: from content creation to graphics, illustration and animations, all the way to programming and testing. SERVICES HappyWise Trainer is an easy-to-use and motivating e-learning solution for informing patients and training staff in hospitals and health care clinics. The solution can be highly tailored to meet different needs. With HappyWise Trainer, health care personnel

can save time and improve the quality of service, for example by giving instructions to post-operation patients or persons with newly diagnosed illnesses. MAJOR ACKNOWLEDGEMENTS We have received positive feedback from our clients on the easy-to-use, fun and motivating solutions that have enhanced their businesses.

� Head office: Oulu Size: 4-10 persons The year of the establishment 2006 CONTACT HappyWise Ltd Paula Karppinen paula.karppinen@happywise.com www.happywise.com

REFERENCES We have various client companies, for example in the education, dentistry, cleaning and service sectors.

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BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

HEALTH INNOVATION ACADEMY LTD We help executives, entrepreneurs, educators and health professionals to succeed with health technology and innovations. We create health tech training platform with digital content and share our expertise. Our values are clarity, openness and collaboration.

SPECIAL KNOW-HOW We have 20 years of experience in health technology and innovations. PRODUCTS/SERVICES • Training and education: We arrange health technology and innovation workshops, courses, executive briefings and lectures. • E-tools and content: We create columns, articles, videos, interviews, guidebooks and e-books about health technology and innovations. • Expert services: We produce innovation events, executive briefings, digital health product concepts and conference reports. REFERENCES Health Innovation Academy is a trusted innovation partner and advisor for many world class medtech and pharma companies and education providers. Many of our clients are new to health tech and we can help them jump in this fast developing category. Our clients say they like our hands-on spirit, high quality and nimble yes-can-do attitude. Our public portfolio can be found on our website.

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� • 1 person + co-operation network • 2014 CONTACT Eeva Kiuru +358-40-5886237 eeva.kiuru@healthinnovationacademy. com www.healthinnovationacademy.com twitter: @HIAforHealth, @eevakiuru LinkedIn: eevakiuru


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNSS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

HORSEGENETEST EUROPE LTD HorseGeneTest Europe is a Finnish company founded in 2012. The company provides innovative and reliable genetic tests for equestrian sports’ needs. The tests give accurate and beneficial information on the genetic parameters and abilities of horses. Tests offered by HorseGeneTest Europe have been developed in partnership with Asper Biotech.

HorseGeneTest Europe’s mission is to bring a modern scientific approach and tools for equestrian sports’ needs. The company’s goal is to serve clients globally with innovative, reliable and beneficial products and make them easily accessible for everyone involved in sport horse industry.

� CONTACT Sakari Juusola HorseGeneTest Pääskystie 28 90650 Oulu - Finland mobile: +358 40 838 4955 e-mail: sakari@horsegenetest.com

ABOUT OUR PRODUCT SYNCHROGAIT SynchroGait gives proof of genetic ability for speed, coordination & rhythm in harness racing. It explains why some horses are good at trotting or pacing while others are not. With the help of a SynchroGait test result you can define an optimal development and training plan for the horse at an early stage. This helps to minimize training effort and saves time and money. SynchroGait test gives also valuable information for the breeding process.

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BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

INNOKAS MEDICAL LTD Innokas Medical provides services in product development, manufacturing and life-cycle management for medical and in-vitro diagnostic Equipment. With over 200 employees in engineering and manufacturing teams, Innokas has become a well-known service provider in medical device Industry.

SPECIAL KNOW-HOW Product development, manufacturing and lifecycle management for medical and in-vitro diagnostic equipments. PRODUCTS / SERVICES Innokas Medical is a Finnish contract design and manufacturing company in the health technology. We offer tailored, comprehensive service solutions in healthcare technology. Our service solutions cover the entire life cycle of products: our high-quality, advanced design and manufacturing processes allow us to serve our customers from the idea phase to the production of high-quality final products. We also provide comprehensive repair and maintenance services throughout the entire life cycle of medical products, even after their production has ended. Our method and model of operating allow significant expansion of capacity according to customer needs. The life cycle of medical devices is long, and we are committed to serving our customers during the entire life cycle of the products. Indeed, our business operation is based on a customer-oriented andventhusiastic attitude, and robust experience and expertise in the health technology sector.

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We have a very enthusiastic, professional, and motivated staff that serves our customers in a flexible and experienced manner. We have a high level of special expertise in the medical field which goes back decades—our staff is comprised of competent, well-rounded specialists who have robust experience in the field of health technology. MAJOR ACKNOWLEDGEMENTS ISO 9001:2008 and ISO 13485:2003 Certified and FDA-registered company. REFERENCES Elekta Oy HLD Healthy Life Devices Oy Modz Oy Nexstim Plc Orion Diagnostica Oy Relaxbirth Ltd Sartorius Biohit Liquid Handling Oy Sooma Oy

� Head offices, other offices: Headquarters in Kempele, Finland and other sites in Helsinki, Finland and Tallinn, Estonia Size (Staff, revenue etc.): Staff n. 200, revenue n. 23M€ The year of the establishment: 1994 CONTACT Headquarters: Innokas Medical Vihikari 10 90440 Kempele Finland Tel. +358 8 562 3100 innokas@innokasmedical.fi www.innokasmedical.fi


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

INSPECTOR SEC LTD Inspector Sec Ltd. is strongly growing indoor air quality expert in Finland. We are the leading company in health-based indoor air measurements. Our superior products are the room & building specific and individual risk analyses. We focus on solving indoor air quality problems effectively and economically with satisfaction guarantee by using air purifier and ventilation systems. The advanced solutions are generated in cooperation with leading researchers. Our company has a strong competence in measuring and decreasing indoor air related health risks.

SPECIAL KNOW-HOW • Target the indoor air problem by using risk assessment building. Rooms are divided into three categories by using risk assessment: low, elevated and high-risk areas. That’s how the health protection actions can be applied to appropriate areas to achieve maximum effectiveness with fewer resources. Risk assessment is based on the toxicity measurements of dust, user survey and expert analysis. • A strong competence in measuring and decreasing health risks related to indoor air. Well-chosen and timely response actions, building-related ill health symptoms can be minimized.

REFERENCES Inspector Sec Ltd has dozens of big customers in Finland. We have, among other things, toxicity-related inventions and IPR rights. World’s widest research of indoor air toxicity and the link between the building-related ill health symptoms used Inspector Sec Ltd’s sampling methods, and the samples were examined in our laboratory in Oulu 1). Inspector Sec Ltd. is cooperating with the leading researchers of this area, e.g. Department of Applied Chemistry and Microbiology, University of Helsinki.

� Head office: Oulu Other office: Vantaa, Jyväskylä Laboratory: Oulu (www.finas.fi) Size: over 20 employees. 80 % of employees have University degree. Turnover 8/14: 1 065 000 € The year of establishment: 2006 Sales have increased more than fifty percent per year in last two years. Preparing to be a global player in indoor air sector. CONTACT Inspector Sec Ltd. Address: Kääpätie 3, 90820 Kello. Telephone number: +358 50 386 9194. E-mail: info@inspectorsec.fi Internet: www.inspectorsec.fi

PRODUCTS/SERVICES • The room and building-specific risk assessment • Multivariate analysis • Indoor dust cell toxicity measurement • User survey • Fast indoor air quality problem reduction with satisfaction guarantee • Airstatic air purifier and ventilation systems • Monitor the effectiveness of actions making successful health protection • Symptom questionnaire before and after indoor air problem decreasing actions MAJOR ACKNOWLEDGEMENTS Inspector Sec Ltd ethics are formed by professionalism, loyalty, confidentiality and responsibility.

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BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

J. NUOSMAA LTD J. Nuosmaa Oy is a multiply skilled company of ecological heating systems. Wood is our main field of expertise. We help you to find the best possible heating system that combines an ecological approach with efficiency.

SPECIAL KNOW-HOW We offer tailored heating system solutions for your home. Ecologically. PRODUCTS/SERVICES We have chosen the best products from leading European manufactures. Our product category is as follows: • Boilers (wood, pellets, woodchips) • Boiler stoves • PVT-panels • Accumulator tanks • Fan convectors We proudly offer the following brands: Akvaterm, Atago Design, ETA, Smith’s, Vigas and Wiosun. MAJOR ACKNOWLEDGEMENTS Co-operating with high-quality manufacturers, we guarantee you the most effective and reliable products and an optimal combination. REFERENCES J. Nuosmaa Oy is the first Finnish company importing most of these trademarks.

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� J. Nuosmaa Ltd Size of staff: 4 The year of the establishment: 2006 Having made a strong career in many technology industry companies and having worked in Finland and abroad, our CEO Juho Nuosmaa has gained strong experience in the area of heating systems. During these years, he has met the leading European manufactures. Thanks to his ambition, knowledge and skills, he founded the company which now imports the best available products to Finland. CONTACT J. Nuosmaa Oy Rantatie 11, 85410 Sievi 044 585 1041 sami.ronkainen@nuosmaa.fi www.nuosmaa.fi


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

JOUZENET CONSULTING LTD JouZeNet Consulting Ltd is specialized to consult company managements in the field of life-sciences, diagnostics and biotechnology.

SPECIAL KNOW-HOW • The company offers expertise in planning and managing development projects and programs requiring external funding in the field of life-sciences, diagnostics and biotechnology. • Recently, the company has been in charge of the financial management of research programs related to strategic health and well-being with a total research budget of 60 million €. • The company has long-term experience in development, manufacturing and marketing in vitro diagnostic medical devices, including domestic networks with academia and bioindustry, international partnerships, IP management and FDA registrations.

PRODUCTS/SERVICES • Consultation in development projects and programs in health and well-being (including Tekes funding, networks) • Consultation in crucial areas of in vitro diagnostic medical device industry (including IPR , FDA, partnerships)

� Head office: Kempele, Finland Size : Staff 2+ The year of the establishment : 2012 CONTACT Jouko Haapalahti, MD.PhD(hc.), eMBA President & CEO JouZeNet Consulting Ltd Köykkyrintie 28, 90450 Kempele +358 440 419 477 consulting@jouzenet.fi www.jouzenet.fi

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BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

KIDE CLINICAL SYSTEMS LTD Kide Clinical Systems was founded in 2015 by four medical imaging professionals with over 50 years of experience in the sector. Their long history in the sector has resulted in an extensive network covering service providers, hardware vendors and customer organizations. Kide Clinical Systems’solutions are used in over 300 optic shops in all Nordic countries and in several hospitals and hospital districts in Finland. SPECIAL KNOW-HOW Kide Clinical Systems specializes in providing solutions to visible light clinical market (e.g. ophthalmology, endoscopy). Our main target is to provide the whole workflow from the imaging device connection to archiving and telemedicine. KIDE web based solutions work with all modern browsers and operating systems and are designed to match current and especially future requirements of clinical imaging. Our solutions have been designed in cooperation with physicians and other healthcare professionals to offer excellent usability and performance. PRODUCTS/SERVICES The uniqueness of our products lies in a holistic service and technological innovation. All the software components are provided via web, which removes the need for local installations.

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We offer holistic solutions for the whole imaging process to be used in the following fields: • Ophthalmology • Endoscopy • Optometry • Sonography • Hospital’s generic imaging needs

� Staff: 6 Established: 2015 CONTACT Kide Clinical Systems Ltd Head office in Oulu: Hallituskatu 13-17 F 53, 90100 OULU, Finland Sales office in Helsinki: Viikinkaari 6, 00790 HELSINKI, Finland info@kidegroup.com www.kidegroup.com +358 20 734 8190


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

LATURI LTD Laturi designs and delivers high-energy corporate wellness tools. Our goal is to help people adopt a healthy and active lifestyle. We believe that physical fitness is the foundation upon which a business can build a productive and profitable future.

SPECIAL KNOW-HOW As healthcare costs are rising companies seek solutions to take action to improve wellness at work. Laturi’s tool helps businesses producing corporate fitness services to map out the fitness level even in a larger work community in a cost-efficient manner. The Energy Test is also an excellent tool to boost and support the work of a personal trainer. This easy-to-use fitness assessment tool helps to motivate the customer. PRODUCTS/SERVICES The Energy Test is a new type of fitness assessment tool. After having done the Energy Test developed by Laturi, you receive a personal Energy Index. The Energy Index indicates the amount of time during which you can experience your peak energy output. The whole test is comprised of easy-to-perform subtests that include a fitness assessment, a wellness questionnaire and biometric data. These subtests estimate different health risks reliably and provide useful results for people of all fitness levels. The Energy Test is specifically designed for corporate wellness purposes. The test takes the most important factors into acccount when assessing a person’s ability to work.

MAJOR ACKNOWLEDGEMENTS In 2013, Laturi won the first prize in the competition of most innovative enterprise ideas (Pohjois-Pohjanmaan Yrittäjien Innovatiivinen Yritysidea -kilpailu). Laturi’s Energy Test was picked out from more than 20 enterprise ideas. According to the jury, “the winner has commercialized its idea extremely well. The product is easy to use and easy to understand.”

� Laturi Corporation was founded in Oulu, Finland in 2012. It employs 6 people and has offices in Oulu, Vantaa and San Francisco. Laturi’s team has more than 60 years of experience in wellness technology. CONTACT Laturi Corporation +358 (0)400 179 200 info@laturi.com www.laturi.com

REFERENCES/SELECTED REFERENCES The Energy Test was selected as the 2013 Sports Product of the Year in the service and concept category. The competition was held in Finland with 44 companies taking part in it. A jury selected a winner for three different categories evaluating the product’s innovativeness, market potential, quality and usability. One of the additional criterias was the product’s ability to motivate people to exercise in a fun and engaging way.

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BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMA CEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

LEWEL GROUP FINLAND LTD Lewel Group Finland Oy is an R&D services provider company. Lewel is a strategic onestop product development partner, providing its customers with high-quality wireless, medical and industrial solutions with R&D and productization services. The company has three sites in Finland and over 80 engineering experts in different fields of technologies. Lewel Group - Excellence in every step.

SPECIAL KNOW-HOW • We understand the qualitative and regulative requirements like MDD/IVD EU and FDA regulations, IEC 60601 and ISO 13485. • We know how to integrate wireless technologies into medical and health care devices. • We have vast experience in designing products for harsh environments. • We have an extensive partner network for validation and clinical trials. • Our global partner network for NPI services and ISO 13485:2003 manufacturing is available for our customers. • Our customers get everything they need from one partner! PRODUCTS/SERVICES Please note that the most important information about the products and services concerning life science sector is valid. From technical implementation through R&D resources to specific product development. Our service products cover all aspects of product development – tailored to meet the customer’s requirements. Technology studies and concept - A precise plan as a base for product development. Well-performed preliminary work ensures that your product will be a success when launched on the market. Our service includes product definition and concept design, finding the right technological solution, analysis of technological risks and a preliminary estimate of the material costs. Design Engineering – Our design services include system engineering, RF Electronics Engineering, Analog and digital Electronics engineering, PCB design, DSP and embedded SW development, mechanical design engineering and industrial design. Product testing - The careful product testing is 38 / LIFE SCIENCE IN OULU

an essential part of the product development process. It improves the product quality and ensures that the product will meet the requirements. We offer a wide range of testing services including R&D testing, type approvals, failure mechanism and root cause analyses. New Product introduction (NPI) - With our NPI service package we ensure that the product can move from product development to manufacturing fluently and trouble-free. Our services include production and supplier approvals, production testing planning and realization of testers and product maintenance throughout its life cycle. As a result, customer’s product is cost-efficiently launched on the market. Product maintenance services We ensure the quality of a new or existing product, minimize the costs related to product manufacturing or maintenance, and ensure that the product life cycle continues. REFERENCES • Wellness products such as sports computers, heart rate monitors and monitoring systems for the elderly • Home and remote control medical and in- vitro-diagnostic devices, such as blood glucose meters and ECG monitors • Hospital, treatment and laboratory testing devices, such as analyzers, biomedical signal processing • Components of surgical equipment and imaging systems, i.e. surgical navigators and imaging systems

� Head offices: Oulu other offices: Kuopio, Espoo STAFF: 87 ESTABLISHED: 2010 CONTACT Lewel Group Ltd Elektroniikkatie 10 90590 Oulu www.lewelgroup.com


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

LOJER LTD Lojer Group is a Finnish market leader in hospital and care furniture, and the country’s biggest employer in the field. The company was founded nearly 100 years ago and is still privately owned. Its manufacturing facilities are located in Sastamala, Kempele and Pennala. Lojer’s unit in Kempele is specialized in manufacturing hospital and nursing beds.

SPECIAL KNOW-HOW Finnish medical furniture specialist Lojer designs and manufactures hospital equipment to serve healthcare professionals in demanding environments. Lojer has over 30 years of experience in designing and manufacturing hospital equipment that fulfil the European medical standards. Our wide range of products and services means that we are able to offer everything needed to equip hospitals with modern hospital and care furniture. PRODUCTS/SERVICES Lojer Group is a leading producer of medical furniture and physiotherapy equipment in the Nordic countries. Our range of products covers hospital and care beds, examination tables, operating tables, medical fitness equipment and massage tables as well as equipment for physiotherapy. We provide innovative and unique products manufactured in Finland to the highest quality standards, marketed around the globe by skillful and dedicated staff. We are committed to giving healthcare professionals easy access to sustainable medical equipment and tools for effective patient care and treatment today and in the future.

REFERENCES Lojer products are in use in over 100 countries around the world, and our retailer network covers over 50 countries. Our products are currently being used in numerous public and private hospitals, clinics, care homes, health centres and physiotherapy chains throughout Europe. Finnish customers include Terveystalo, Mehiläinen, PPSHP, HUS, Caritas-Säätiö, Esperi Care, Diacor and Red Cross.

� Net sales: 20,5 Meur (2014) Employees: 140 (30 in Kempele) Head office: Sastamala Manufacturing facilities: Sastamala, Kempele, Orimattila Sales offices: Moscow, Stockholm, Espoo, Hollola Established 1919 (Vammalan Konepaja) History: Lojer Group was founded when leading Finnish producers of furniture for health care and physiotherapy - Vammalan Konepaja Oy, Temelex Oy and Rainer Rajala Oy - and the leading Swedish supplier of physiotherapy equipment, Medema Physio, decided to merge. CONTACT Lojer Oy Pikkutie 4 90440 Kempele Email myynti@lojer.com Tel +358 10 830 6700 www.lojer.com

Lojer complements its comprehensive range of hospital equipment by offering its customers a wide range of maintenance and service solutions to keep the products in good order. A totally new kind of concept, our Functioning Care Facility service, ensures that a hospital or care facility always has safe, working equipment. Lojer owns and takes full responsibility for the equipment and their maintenance; the customer has a facility with modernand well-functioning equipment, and where equipment is fully maintained and regularlyserviced by the manufacturer. LIFE SCIENCE IN OULU \ 39


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

MEDANETS LTD We are developing and providing mHealth solutions for healthcare professionals to improve and optimize care processes and improve patient security.

SPECIAL KNOW-HOW We deliver overall system solutions for healthcare professionals. Our solutions are always extremely user-friendly and secure. We are forerunners in utilizing barcode and RFID/NFC technology for user, patient and device identifications. We are also one of the few companie that are utilizing automatic Bluetooth connections for filing measurement data in a quick and secure way. Our solutions are always integrated in hospital information systems.

are integrated with all the main hospital information systems in Finland. Our quality system is ISO-13485 certified.

PRODUCTS/SERVICES Medanets ABS Wireless Filing: Nursing staff can record, save, and browse the results of patient measurements and medication by the bedside using smartphone, tablet or light weight PDA.

We have also partnerships with main hospital information system providers in Finland, and Medanets ABS solution is integrated with their systems.

Medanets ABS Automatic Filing: Solution enables an automatic transfer of measurements and readings from patient monitoring systems all the way to the hospital information system through Medanets ABS platform server. Medanets ABS Wristband Management: Easy patient wristband management solution integrated with the hospital information system. Medanets ABS Mobile EPR: The best smartphone and tablet solution for healthcare sector, especially for doctors. MAJOR ACKNOWLEDGEMENTS 13 out of 20 healthcare regions in Finland are our customers and our solutions

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REFERENCES E.g. Varsinais-Suomi healthcare region, Etelä-Pohjanmaa healthcare region, Itä-Savo healthcare region, Pirkanmaa healthcare region, Satakunta healthcare region, Carea healthcare region, Eksote healthcare region, Vaasa Central Hospital and Hämeenlinna Central Hospital.

� Oulu-based company with 8 employees, founded in 2004. The development of Medanets ABS Wireless Filing started in 2008 and today it’s our flagship product. We have achieved significant growth with this solutionand expect the good performance to continue. CONTACT Juha-Matti Ranta Kiilakiventie 1 90250, Oulu tel +358 44 566 4999 juha-matti.ranta@medanets.com


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

MEDENGINE LTD MedEngine, founded in 2014, bridges medical science with business. We provide expert scientific research, fully customized digital and traditional communications, tailored medical affairs, and advisory services to the medical and pharmaceutical industries. Diversity, attention to detail and agility are our strongest assets, and we move nimbly from endeavor to endeavor – be it a multi-year research project, scientific advisory for the commercialization phase of a drug, or conceptualization for a health-tech startup.

SPECIAL KNOW-HOW Our team has extensive academic expertise and years of experience working in the medical and pharmaceutical industries where standards for science and quality are rigorous. We’re also scientists and thinkers with a passion for business and entrepreneurship — we actually understand the science behind your product. PRODUCTS/SERVICES Our science and research consists of fully tailored medical science research projects and exclusive access to data of immense value. We carry out the entire process, from the initial study design to the final publications. MedEngine’s Communications team consists of highly skilled copywriters with PhDs in medical sciences, a communications department with a native, MFA-level English speaker, and an art department that provides brilliant and compelling graphics and visuals. MedEngine also handles complex medical affairs.

uses science-based marketing practices to add credibility to your campaigns, while our Concept Accelerator utilizes science, research and gut instinct to help you determine your company’s long-term strategy and big-picture conceptualization. REFERENCES MedEngine works for some of the largest pharmaceutical companies in the world, including Pfizer, Otsuka, Takeda, Teva and many others.

� Size: 7-10 employees History: MedEngine, established in 2014, grew out of the need for a comprehensive medical science agency that bridges medical science with business. MedEngine combines scientific expertise with industry know-how to provide the highest quality scientific data, clear and precise communications and elite scientific advisory. CONTACT MedEngine Oy +358 40 901 2975 info@medengine.fi www.medengine.fi

We do everything from classical scientific advisory to planning and management of complex projects, including: key opinion leader relations; advisory board management; market access support; medical education programs and materials; event planning; marketing materials review and medical information services. We offer venture services to medical, biotech and health-tech enterprises. Our Optimized Marketing service

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BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

MEDFILES LTD Contract Research Organization: Analytical & Formulation Laboratories – Local & International Services, Partnership in Clinical Development & Marketing, Authorization Services. Access to expertise in more than 90 countries, Food and Nutrition services.

SPECIAL KNOW-HOW Medical Device • In-house expertise within combinational products & IVDs. Public Healthcare • Supporting public and private healthcare providers with services such as investigator initiated studies, training, health economics reporting & consulting Pharmaceutical & Biotech • Providing insourced and outsourced solutions e.g. Expert know-how, Clinical studies, Pharmacovigilance, Regulatory Affairs, CAPA Training, Pricing and Reimbursement services & Laboratory R&D/ Analytical services. Food and Nutrition • Regulatory affairs and clinical studies PRODUCTS/SERVICES Key offering: • Market Access Services • Analytical & Formulation Laboratory Services • Healthcare & Therapeutic Focused Services i. Key fields: Oncology, Vaccines, Paediatrics, Respiratory, Endocrinology, Rheumatology, Cardiology ii. Key Areas: Medical Devices- combinational products & IVDs • Food and nutrition • Operational study management services

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MAJOR ACKNOWLEDGEMENTS • “The Strongest in Finland 2014” certificate • “Kauppalehti’s Achiever 2014” certificate REFERENCES • Sanquin • Nordic Infu Care AB • Orion • Biotie Therapies • Genzyme • Novo Nordirk • Accord Healthcare

� Nordics: 5 offices Baltics: 4 offices Established in 1987, privately owned. With more than 150 staff members, Medfiles is a well-established Contract Research Organization (CRO) with over 25 years of serving the needs of our healthcare clients. Our service portfolio describes the changes in those needs as well as the adaptability of our company. We have maintained strong growth and continually seek out new services as well as new locations. Our customers are an integral part of our company´s strategy and the people that work for Medfiles reflect this through their responsive, responsible and friendly attitude. CONTACT Oy Medfiles Ltd Otavansakara 10 90630 Oulu Finland www.medfiles.fi


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

MEDIRACER LTD We specialize in Point of Care products in clinical neurophysiology. Our hand-held nerve conduction system helps medical doctors with diagnosing of carpal tunnel syndrome and ulnaris entrapment in the elbow at an early stage of the treatment path, contributing to reduce medical and sickness absence costs by enabling the right kind of treatment for patients, which is faster compared to conventional methods. Our multidisciplinary team of experts includes internationally recognized medical specialists, biomedical engineers, software engineers and business professionals.

SPECIAL KNOW-HOW Mediracer® NCS enables testing of both carpal tunnel syndrome and ulnar nerve entrapment, resulting to 80% of upper extremity nerve entrapments. Carpal tunnel syndrome is one of the most common upper extremity problems with 3-5% prevalence in the adult population. In addition, about 15% of the population suffer from occasional carpal tunnel syndrome symptoms; numbness, tingling and pain in the hand. Undiagnosed and untreated carpal tunnel syndrome may have long lasting illeffects. Whether the treatment is non-surgical or surgical, an early diagnosis is crucial. With the Mediracer®NCS you will be able to confirm carpal tunnel syndrome quickly, costeffectively and reliably; sensitivity 94% and specificity 98%. PRODUCTS/SERVICES Mediracer® NCS is an accurate, efficient and reliable tool for general practices, occupational health care, surgeons, health care professionals and allied clinical support staff. Mediracer products are developed in collaboration with specialists in clinical neurophysiology, hand surgery, and occupational health. Testing method is noninvasive and it is easy to carry out the test using disposal electrode. With Mediracer® NCS nerve conduction examination can be done by medical staff in just 15 minutes, and it doesn’t require extensive training. It is also a costeffective method compared to conventional methods.

MAJOR ACKNOWLEDGEMENTS Mediracer Ltd. has achieved ISO 13485:2003 certification for its quality system. Mediracer Ltd. received Winner of the Medical futures innovation award/Best Diagnostic in the Bone & Joint Innovation Awards 2007 in London, UK. REFERENCES Mediracer nerve conduction system is used in over 100 locations worldwide. In Finland, over 2,000 Mediracer nerve conduction studies are conducted in 50 health care locations annually. • Green, T., Kallio, M., Clarke, M., Pathak, P., Lesonen, V. and Tolonen, U. (2011) Carpal tunnel syndrome diagnosis: validation of a clinic-based nerve conduction measurement device. Journal of Biomedical Science and Engineering, 4, 282-288. doi: 10.4236/jbise.2011.44038. • Tolonen, U., Kallio, M., Ryhänen, J., Raatikainen, T., Honkala, V., Lesonen, V. and The Study Group. A handheld nerve conduction measuring device in carpal tunnel syndrome. ActaNeurol Scand: DOI:10.1111/j.1600-0404.2007.00799.x 2007 The Authors Journal compilation 2007 Blackwell Munksgaard.

� Mediracer Ltd was founded in 2002. The company is headquartered in Oulu, Finland andhas distributors in Japan, UK, Denmark and Australia. Mediracer Ltd is a part of the Oulu-based Head Invest Group, which owns several companies in Oulu, Finland and worldwide. CONTACT Mediracer Ltd. Rantakatu 4 90100 Oulu Finland +358 45 899 2626 info@mediracer.com www.mediracer.com Yoko Keränen +358 (0)400 11 4175 yoko.keranen@mediracer.com

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BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

MEDKIT FINLAND LTD MedKit Finland is professional company providing first aid equipment. The company relies strongly on the experience gained from major global catastrophe regions. Founded in 2008, we are now the leading emergency medical equipment supplier in Finland. Our values: Customer first! Ease, speed and high-quality service. Our belief: Accidents do happen, be prepared! Our vision: To be a global player in emergency medical supply business by 2020.

SPECIAL KNOW-HOW The key person behind the company is MD Tuukka Toivio who had the business idea of importing EMS to Finland while he was helping Royal Med launch its air ambulance operations in Dubai during 2003-2007 . Mr Toivio is one of Medkit’s founders, and has been confronted with several international emergency situations such as: earthquakes in India, the tsunami in Thailandand the war in Afghanistan and Nigeria. In addition, he has over 15 years of experience in helicopter rescue operations in Finland. This extensive experience and expertise is the backbone when Medkit’s initial product catalogue was developed. PRODUCTS/SERVICES 1816 Products listed online: • tactical first aid • first aid & emercency medical services • emercency care education & training • consumer products • defibrillators & electrodes • first aid & first care bags • sports first aid & care • workplace safety & first aid

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From a single product to a comprehensive one stop shop solution! MEDKIT’S SINGLE VENDOR MODEL is something our clients have appreciated. MAJOR ACKNOWLEDGEMENTS We also specialize in complete, single source solutions for our customers’ needsmaking the whole purchasing process as easy and costeffective as possible. REFERENCES • hospitals, health centers, clinics • first aid centers • rescue stations (transportation), first responder operations • police • cities, municipalities • government agencies (inc. Finnish defense forces) • industries, private companies • sports, clubs • emercency medical services • www.medkit.fi/asiakkaitamme

� Head offices: Oulu, Finland Size: 6 person Annual turnover: In 2014, appr. 1,5 Meur, Annual growth rate: appr. 20-75%. Founded: 2008 History: The enterpreneurs decided to invest on an e-commerce channel within a very conservative field of business – and did it successfully. CONTACT CEO Minna Åman-Toivio MedKit Finland Oy Haarasuontie 6 90240 Oulu, Finland Tel. +358 40 502 5761 Minna@medkit.fi www.medkit.fi


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

MEKITEC LTD With years of dedication to develop a new generation of food quality control, we now provide the most innovative X-ray food quality inspection systems that detect and remove physical contamination and irregularities in food products. Founded in 1991, we are the leading Nordic manufacturer of X-ray food inspection systems. Our headquarters is located in Oulu and with our foreign offices in Germany, USA, Hong Kong, China together with our distributor network we operate in three different continents and employ over 40 people.

SPECIAL KNOW-HOW The founders of Mekitec have a combined experience of several decades in the development, industrialization and manufacturing of X-ray imaging systems applied in medical, security and safety areas. This unique combination of in-depth knowledge of various industries has enabled the company to do long-term research and development in the food industry.

inspecting productions of very high volume. To create a fully integrated inspection system we also offer our own rejecters, rejecter box and scales to ensure safety and quality of our customer products. With our own software to manage the system and our distributor network we can provide the best support and maintenance to our systems.

� CONTACT Mekitec Oy Juho Ojuva, Key Account Manager Juho.Ojuva@mekitec.com +358 (0) 40 546 1881 Teknologiantie 3, Oulu 90590 www.mekitec.com

Currently, our food inspection system product line consist of three main products: MEKI, MIDMEKI and BULKMEKI. They are designed to work in various factory environments, such as in high humidity or freefall applications. They simultaneously perform several functions from shape and weight inspection to complete content inspection. Because of the highly adaptive system, we have clientele in various food industries such as bakery, meat, cheese, nutrition protein powder, bulk sugar, rice, grain, frozen shrimps and convenience food. MEKI is our first product that has the accuracy and efficacy of a traditional x-ray system, but in a much smaller and compact size and at a significantly reduced cost. MIDMEKI is designed for the inspection of larger food products, trays of smaller products and multiple lines BULKMEKI is designed to inspect product flow in an adjustable angle, which makes it the first x-ray device to inspect conveyor free continuous flow. Due to the large crosssection of the high-speed and continuous flow, BULKMEKI is capable of reliably

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BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

NORTAL LTD Nortal Oy is a high-end software development solutions and on-line services provider. Nortal Oy is a part of the international Nortal Group, which is the biggest software development solutions provider in the Baltics and one of the fastest growing software companies in Northern Europe. Nortal’s success is built on long-lasting customer relations, understanding customers’ business processes and successful deployment of mission-critical solutions and services.

SPECIAL KNOW-HOW A key to our success in Health-IT has been working closely with both administrators and medical specialists to achieve appropriate solutions with superior usability. When put in use properly, IT can deliver serious gains. It is important to clearly map the goals of a project or organization and think how the results can help a health care center ora patient in one of these ways: • Improved access to data supports medical specialists in decision-making - which improves care quality and reduces waste on redundant procedures • Providing access to patients empowers them and increases accountability within the system • Process standardization and automation increase operational efficiency, improve user experience for both patients and medical specialists and help secure service quality • In addition to lowering costs, this also helps medical specialists to focus on patients instead of refilling or searching for data • Consolidation of data and wider access also facilitate better decision-making on health care administration levels

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PRODUCTS/SERVICES Nortal’s health care offering: • Hospital management • Patient portal • Family doctor portal • eDiagnostics • Picture Bank • National Health Record • Health Integration Platform • Big Data REFERENCES Nortal’s Healthcare references: • Tartu University Hospital • East-Tallinn Central Hospital • Estonian Medical Image Bank • Estonian eHealth Foundation • Estonian Agricultural University • Lithuanian National Health Record • Lithuanian National Patient Portal • Lithuanian National Doctor Portal • Labquality • Quattrome

� Main office: Tietotie 2, 90640 Oulunsalo Other offices: Helsinki, Turku, and Uusikaupunki Nortal Group Head office: Lõõtsa St 6C, Tallinn 11415, Estonia Staff: in Finland 150 of 620 in total Revenue: 36 million € Nortal has been operating in Finland since 1985 CONTACT Jaana Kähönen Business Development Manager Tel: +358 50 500 4095 jaana.kahonen@nortal.com Juha Manninen, Director Tel: +358 40 671 6145 juha.manninen@nortal.com www.nortal.com


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

OPTOMED LTD Optomed Oy (Ltd.) is an innovative Finnish medical technology company that specializes in retinal imaging devices and solutions.

SPECIAL KNOW-HOW A unique skill set of optical, electrical and software expertise combined with extensive health care and medical device business skills. Optomed’s mission is to drive down the cost of treating eye diseases to a level where it will be no more a bottle neck in the path to eradicate avoidable blindness in the world. Optomed is committed to develop and manufacture more effective and affordable eye fundus imaging devices, image management solutions, automatic diagnostics algorithms and innovative services, and offer these through most effective sales and distribution channels.

REFERENCES Optomed has a global distributor network with more than 20 leading distributors. Devices are being used by private clinics, public hospitals, non-government organizations and charities around the world.

� Optomed is a privately owned company headquartered in Oulu, Finland, with a subsidiary Optomed China Ltd., and offices also in Southern Finland and in India Optomed has over 50 employees. CONTACT Optomed Oy (Ltd.) Hallituskatu 13-17 D 90100 Oulu, Finland +358 20 741 3380 info@optomed.com www.optomed.com

PRODUCTS/SERVICES The product portfolio consists of unique digital imaging instruments that provide retinal, anterior, otoscopic and dermatoscopic imaging with one portable device. Optomed’s key product is Smartscope® M5, a modular hand-held retinal camera for screening and diagnosis of various eye diseases, such as diabetic retinopathy, glaucoma and AMD. It is the smallest product on the market with high image quality that meets international ISO 10940 fundus camera standard requirements. MAJOR ACKNOWLEDGEMENTS Thousands of Smartscope® M5 cameras have been sold since 2011 and it is registered in major key markets: Europe, China, Russia, Japan, Korea and US. Smartscope is also on IAPB’s (The International Agency for the Prevention of Blindness) standard list since September 2012, and has become one of the best-selling fundus cameras in the world.

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BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

OTOMETRI LTD Otometri, founded 2010, has developed an ear infection measurement solution available 24/7 for home use. The solution is based on acoustic measurement and advanced internet technologies. The product is available on Finnish markets and is applied in selected health care processes. The company has a giant market opportunity – ear infection is the most common reason for small children’s visits to doctor in Finland (500 000 visits every year). The problem is global, and the solution is easy to scale.

SPECIAL KNOW-HOW Ear infection is most common reason for small children’s visits to doctor in Finland (500 000 doctor visits every year), the total cost amounting to more than 100M€/year. The problem is global. Otometri’s speciality is to manage the entire health care need, measurement technology, science and commercializing in its focus field by effective co-operation with required partners. PRODUCTS/SERVICES The product is Otometri measurement device and web-service establishing quantitative ear infection measurement. The measurement is an essential part of an advanced ear infection care process. The measurement system has proven clear benefits, which have resulted in an expanding integration of Otometri health care service providers.

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MAJOR ACKNOWLEDGEMENTS Several local innovation awards (PohjoisPohjanmaan Innosuomi 2011 1st prize, Pohjois-Pohjanmaan Yrittäjien Innovatiivinen Yritysidea -kilpailu 2011 1st prize, 100 Actions from Oulu, nr 25).

� Head office: Otometri Oy, Ollilantie 4, 90440 Kempele, Finland. The company established year 2010. CONTACT Manne Hannula Ollilantie 4 90440 Kempele +358 45 3219 440 manne.hannula@otometri.fi www.otometri.fi


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

PARAS BIOPHARMACEUTICALS FINLAND Paras Biopharmaceuticals Finland is an acclaimed enabler of biopharmaceutical manufacturing technologies for biosimilars and long therapeutic peptides. Our facilities in Oulu are dedicated to the development, scale-up and GMP production of recombinant products. We offer optimized scale-up technologies and products for clinical and commercial manufacturing.

SPECIAL KNOW-HOW Paras Biopharmaceuticals offers a unique combination of technologies and facilities to deliver biosimilars for the following areas: Osteoporosis, Rheumatoid Arthritis, Diabetes and Oncology. Paras has successfully developed a Propriety Technology platform resulting in high yielding biosimilar technologies within biologic APIs. PRODUCTS/SERVICES Paras’ work revolves around three main streams: • Biosimilars comprised of osteoporosisteriparatide, analog insulins and therapeutic fragment of mAbs • High value recombinant enzymes such as Enterokinase (other enzymes in pipeline). • Innovative Oncology molecule in partnership with an esteemed research institution. Paras’ expanding portfolio of propriety technologies include: • Diabrid® • NobleCleav® • Biomultifold®

MAJOR ACKNOWLEDGEMENTS At Paras, we work on the principle –“Why At Paras, we work on the principle –“Why have complications that you can avoid? Rational design of processes combining academic and industrial expertise means increased efficiency without compromising quality. At Paras, our ultimate objective is to use innovative scientific ideas to make health care more affordable.

� Established in 2012, Paras Biopharmaceuticals is a joint venture between a team of scientists and technologists who have extensive research experience and skills in the development of biologics and biosimilar technologies. Based in Oulu, Finland, Paras’ facilities include modern R&D laboratories and classified cleanrooms. CONTACT Paras Biopharmaceuticals Finland Oy Kiviharjunlenkki 2 90220 OULU, Finland info@parasbiopharma.com Tel: +358 (0) 442709462 www.parasbiopharma.com Skype: Paras.Finland

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BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

PEDIHEALTH LTD Pedihealth is a producer and a distributor of health care products. Our customers are bothpublic and private healthcare units and private consumers. The company was founded in 1986.

SPECIAL KNOW-HOW Pedihealth manufacturers, sells and markets health care products to Finnish and international health care centres, hospitals, private clinics, rehabilitation centers, schools, pharmacies and private consumers. Pedihealth uses the long-term medical experience of its founder, M.D. Pediatrician Seppo Similä. Pedihealth co-operates with companies and educational institutions in the region and with Oulu University Hospital. PRODUCTS/SERVICES Pedihealth is a Finnish producer and distributor of healthcare products. The product range consists of about 2,000 items for primary and special health care for premature babies to elderly people.

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The main product categories are: • Rehabilitation and Therapy • Primary Care • Obstetrics and Gynecology • Specialty Care • Infant Care • Bedwetting Treatment MAJOR ACKNOWLEDGEMENTS The goal of Pedihealth is to provide high quality and competitive products for customers. The aim is to offer customer-orientated and costeffective service. REFERENCES / SELECTED REFERENCES Pedihealth has worked with Finnish hospitals and health care centres since 1986. The company has delivered products to Finnish Maternity Package since 1996.

� Pedihealth Ltd. was founded in 1986. The office is located in Oulu. The Managing director is Mrs. Päivi Kaasinen. The staff consists of 7 persons with different educational background and work experience. CONTACT Pedihealth Oy Svaanintie 4 FI-90230 OULU Tel. +358 207 401 330 Fax. +358 207 401 339 info@pedihealth.fi www.pedihealth.fi www.pedihealth.se www.pedihealth.eu


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

PHARMATORY LTD Pharmatory Ltd. is one of the leading European custom manufacturers of active pharmaceutical ingredients for animal and human health. Pharmatory specialises in route scouting, process research and development, scale-up and cGMP manufacturing of small molecule key intermediates and active pharmaceutical ingredients with focus on quality operation and timely delivery.

SPECIAL KNOW-HOW Pharmatory offers a full range of services related to the chemical development and cGMP manufacturing of active pharmaceutical ingredients. The service highlights are process R&D, enzyme catalysis, isotope labelling and pilot scale manufacturing. Pharmatory is capable of manufacturing GMP batches from milligram scale to tens of kilograms, making Pharmatory a perfect partner for orphan drug and veterinary companies. The key components in all projects are customer orientation and operational excellence with high confidentiality and commitment to exceptional customer service. Pharmatory is routinely inspected by Regulatory Authorities as well as its customers with a clean track record since it was founded in 2001. PRODUCTS/SERVICES The cornerstone of all operations is long experience in the field of human and veterinary health and understanding the customers’ needs and requirements. Pharmatory is committed to continuous improvement and developing sustainable chemistry, in order to better serve its customers in the changing world.

You can find more information about Pharmatory on www.pharmatory.com. MAJOR ACKNOWLEDGEMENTS Pharmatory is committed to operating in accordance with current Good Manufacturing Practise (cGMP) as defined by the current EU, ICH and FDA Guidelines to Active Pharmaceutical Ingredients. Pharmatory has been routinely inspected since 2001 by its customers and the Finnish Medicines Agency making the company a reliable supplier of active pharmaceutical ingredients.

Head office: Oulu, Finland Size: Staff 18 Established 2001 Staff has the industrial and academic research background. CONTACT Pharmatory Ltd. P.O. Box 346, Typpitie 1 FI-90101 Oulu +358 (0)20 765 9988 info@pharmatory.come www.pharmatory.com

REFERENCES/SELECTED REFERENCES Pharmatory tailors the service package according to customers’ individual needs and the company cooperates closely with the customers in Europe, USA and South-Korea. The shared mission is to keep the project running smoothly at all times.

Pharmatory offers the following services: • Route scouting • Custom synthesis and development • Process research and development, scale- up and optimization • cGMP pilot scale manufacturing • Reference material management • Isotope labelling • Enzyme catalysis • Stability testing, impurity profiling • Development and validation of analytical methods. LIFE SCIENCE IN OULU \ 51


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

PROWELLNESS LTD ProWellness has developed and marketed regional solutions for the prevention, care and management of chronic diseases to public and private health care organizations for over a decade. Our mission is to provide best-of-breed tools for preventing growth of chronic diseases and for improving the overall life quality of patients with long-term conditions.

SPECIAL KNOW-HOW The number of patients with a chronic disease will rapidly increase globally in the future. About 45 % of the population have one or more chronic illnesses where 20 % of the diseases cause 80% of the health care costs. Thereforeherefore the role of preventive care and monitoring people with high risk is getting even more important. ProWellness offers a unique product portfolio that covers the whole care pathway from prevention to disease management with extensive auditing and reporting tools that adhere to national audit guidelines. Our objective is to achieve a traceable and reportable care path that helpshealth care professionals and administrators to better manage the increasing amount of information and workload. PRODUCTS/SERVICES Web-based software product solutions for health care and wellness. Our product range includes the following solutions: ProWellness Chronic Diseases Management system including modules for diabetes, chronic lung and heart diseases and retinal screening for the clinical users and SelfCare service for patients. MAJOR ACKNOWLEDGEMENTS British Thoracic Society’s (BTS) Award to NHS Westminster/Imperial College’s COPD team at the BTS Summer Meeting 2013. The

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team was awarded for their COPD CDMS project in which they studied whether the use of ProWellness Chronic Diseases Management system can improve communication and care delivery for patients with COPD across primary (community) and secondary (hospital) care settings. REFERENCES/SELECTED REFERENCES ProWellness has a large customer base in Finland, in more than 50% of the health districts ProWellness solutions are used in primary and/or secondary care. Widely in use in the UK and Ireland. Penetrating into Asia, Middle-East and Africa.

� Head office: Oulu, Finland Subsidiary: London, United Kingdom Representatives in 4 other countries The company established year 1996 CONTACT Oy ProWellness Ltd Teknologiantie 3 D 90590 Oulu Tel. +358 424 55551 prowellness@prowellness.com www.prowellness.com Mr. Markku Savusalo CEO tel. +358 40 154 7970 markku.savusalo@prowellness.com


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

QAAMOS LTD The best applications and services are created based on everyday needs. Those little things that can be done better, easier or funnier. Our mission is to make those little things to ease everyday life.

SPECIAL KNOW-HOW We know the whole package to implement today’s services: cloud services, databases, server back-ends, web interfaces, social media services, crowdsourcing, mobile platforms, native and web applications, user interfaces and graphical design. And yes, we are experienced but agile.

MAJOR ACKNOWLEDGEMENTS During 2013, got a remarkable award for Somefood.org Windows Phone application development from AppCampus, mobile application accelerator program managed by Aalto University and funded by Nokia and Microsoft.

� Headquarted from Oulu Crew of four Established on June 2012 CONTACT Qaamos Viskaalintie 220, 91510 Muhos, Finland +358 40 746 5473 info@qaamos.com www.qaamos.com

PRODUCTS/SERVICES Social Media Food Database – somefood. org. Somefood.org provides personalized and localized food and grocery information to be used wherever and whenever. The main goal is to help people to find the food and groceries suitable for their personal diet and taste. Use, share and contribute – the community is open, neutral and respects privacy. The service consist of solid database, vivid web interface and easy-to-use applications. Check the Finnish version at finland.somefood.org. Interested in establishing a local somefood. org in your country? Get in touch and let’s make it happen together.

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BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

QLU LTD Qlu provides expert services in hearing accessibility to owners of premises and organizations operating in those premises. Our primary product is a proprietary mapping service, where the quality of the signal produced by a hearing loop system is characterized, converted to clear visual form and published as a quality map, locally in a poster and globally in a maps.qlu.fi internet service.

With the help of our services, event organizers can find the premises where the hearing accessibility is properly organized, so they can make sure their customers can hear all the details in the porogram. We help the end user to easily find the best possible seat in the conference, concert, training, church, etc. This results in better customer satisfaction and increases business potential. SPECIAL KNOW HOW We are experts in hearing accessibility technologies and services. We provide hearing technologies related consultancy, training, design and assembly services to our customers.

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PRODUCTS AND SERVICES • Hearing loop signal quality mapping service • Consultant services in hearing accessibility solutions • Training • Design services • Installation projects MAJOR ACKNOWLEDGEMENTS Qlu works in good co-operation with Kuuloliitto (Finnish Federation of Hard of Hearing FFHOH). REFERENCES References can be found in a web service; maps.qlu.fi.

� Head office: Torikatu 19, 90100, Oulu Staff: Team: 10 persons Established 2013 CONTACT DETAILS Juha Nikula Torikatu 19, 90100, Oulu +358 40 5881138 juha.nikula@qlu.fi www.qlu.fi maps.qlu.fi


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

SCREENTEC LTD Our company is a well-known developer and manufacturer of flexible substrate products. The product portfolio consists of user interface products, lightning and illumination products, medical electrodes and integrated hybrid electrodes. In the medical industry, strong product groups for Screentec are specialized user interfaces used in dentistry, operation rooms, diagnostics electrodes and wellness sensors & electrodes. All of our products are customer and application specific and products are based on experience in silk screen printing, converting, assembly technologies and materials to the customer.

SPECIAL KNOW-HOW Our strength lies in the wide expertise of different manufacturing technologies and the flexibility to combine them to reach the best end results. We can integrate printed flexible plastics with traditional electronic components, printed illumination into molded and encapsulated flexible materials to meet the customer needs. Depending on the end product, the result can be a simple medical electrode or a complex multilayered illuminated user interface for harsh environment. We design, prototype and make series production in our own house, which means that we take manufacturability into account already in early stages of design.

� Turnover: <2M€ Personnel: 21 personnel Founded: 1989 CONTACT Antti Tauriainen antti.tauriainen@screentec.com +358 44 5565 822 Screentec Oy Konekuja 2 (P.O. Box 66) 90620 Oulu (90651) Finland www.screentec.com info@screentec.com +3588 556 3160

PRODUCTS/SERVICES Services: • Product development • Manufacturing development • Usability Products: • Medical electrodes • Iontoforesis pads • Stimulation electrodes • Microfluidics components • User interfaces • Flexible product components MAJOR ACKNOWLEDGEMENTS Our company can produce small series with high mix to large volumes.

LIFE SCIENCE IN OULU \ 55


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

SPEKTIKOR LTD Spektikor Ltd. is an Oulu-based company established in 2010. Our mission is to create a series of new disposable electronical products for health care professionals. With all of our products we will save time and lives.

SPECIAL KNOW-HOW We at Spektikor Ltd. are specialized in disposable health care electronics. Our products Spektikor DHBI-1 and 2, both disposable ECG indicators, are already approved according to the Medical Device Directive. Our know-how is based on vast experience with mobile devices, heart rate monitors and manufacturing solutions. PRODUCTS/SERVICES Spektikor’s products, disposable ECG indicators, have been developed to assist the medical personnel in first aid and follow-up situations. Spektikor saves time by making it easy to monitor the patient’s heart rate in all circumstances. The indicators are adhered to the patient with a sticker located in the base of the sensor in the same way as with a normal ECG. The LED unit is placed in a visible area and the device indicates the ECG rhythm by flashing the light whenever it recognizes the R-peak of a patient’s heart. A blue LED light indicates that the rhythm is over 40 and below 120 beats per minute. In case the rhythm goes over or under the set limits, this will be indicated with red LED lights. The numeric display enables to monitor even smaller changes in heartrate. By using our product you can easily monitor multiple patients at once and even from a distance. Spektikor saves time by enabling the followup of a patient’s condition without interrupting in first aid. Spektikor is a very light and small disposable ECG-indicator to be used by first aid professionals.

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MAJOR ACKNOWLEDGEMENTS Start-Up Sauna winner, Innovative Business Idea 2011 finalist. REFERENCES/SELECTED REFERENCES Spektikor is being used by The University Hospital of Oulu, several hospital districts in Finland, Finnish Defense Forces, Ambulance companies and Police. Spektikor products are also approved for NATO NSPA stock in Luxemburg with NATO NGACE-code A653G.

� Head offices Spektikor Oy in Oulu Size Staff 3 2010 First product approved with European Medical Directive CONTACT Spektikor Oy Elektroniikkatie 3, 90590 Oulu +358407453167 info@spektikor.com www.spektikor.com


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

TIETO HEALTHCARE & WELFARE LTD Tieto is the leading health care and welfare ICT solution provider in the Nordic countries. We help health care and welfare organizations to make their services more efficient, while improving safety and quality at the same time. We focus on digitalizing health care and welfare services and opening new opportunities for integrated Lifecare – a seamless care and service chain from birth to old age. As the largest Nordic IT services company, Tieto provides full lifecycle services for both private and public sectors. Our work puts us at the frontline of a wide range of industries. Today we are a team of more than 13,000 technology professionals in 20 countries.

PRODUCTS/SERVICES Comprehensive IT solutions and services for health care & welfare. REFERENCES/SELECTED REFERENCES • Over 40 years of experience in Nordic health care and welfare • Over 1,500 healthcare & welfare customers in the Nordic countries • Over 1,200 healthcare & welfare IT professionals • ISO9001 and ISO13485 certificates

Tieto is the largest Nordic IT services company. Founded in 1968, headquartered in Helsinki, Finland and with approximately 13,000 experts, the company operates in over 20 countries with a net sales volume of approximately EUR 1.5 billion. Tieto’s shares are listed on NASDAQ OMX in Helsinki and Stockholm.

� Tieto is the largest Nordic IT services company. Founded 1968, headquartered in Helsinki, Finland and with approximately 13 000 experts, the company operates in over 20 countries with net sales of approximately EUR 1.5 billion. Tieto’s shares are listed on NASDAQ OMX in Helsinki and Stockholm. CONTACT Esa Haverinen, Sales Director esa.haverinen@tieto.com Yrttipellontie 1 A, P.O. Box 140, 90101 Oulu www.tieto.com/lifecare

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BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

USBIMED USBIMED monitors actively trends and factors affecting health technology development and business domain. USBIMED wants to be your partner in promoting usability, safety, entrepreneurship and market success of health technology.

SPECIAL KNOW-HOW USBIMED has expert knowledge of the special features and regulatory requirements related to medical devices and software, as well as safety-related user interface characteristics and usability. The company contributes to collaboration between clinical environment and industry. A multiprofessional background enables a holistic understanding and approach to all aspects of heath technology. USBIMED’s clients also benefit from high quality in-house professional training services. PRODUCTS/SERVICES USBIMED supports the medical device and software industry both directly and by working together with organizations promoting the health technology business sector. The company also collaborates with clinical environments and various health technology research and development projects. USBIMED offers e.g. the following services: • mHealth expert services for industry and clinical environments • Support for medical device and software usability requirements and process • Regulatory affairs training packages • Support and development services to promote collaboration between industry and clinical environments • Expert article writing for professional publications and other media • Steering group and Board Member working for companies and associations MAJOR ACKNOWLEDGEMENTS For the past years, USBIMED has been operating nationwide and with global partners, with great enthusiasm and earning trust among peers and clients.

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Positive feedback from clients and partners encourages company to work hard every day to contribute to the development of the health technology community. REFERENCES/SELECTED REFERENCES Since the founding of USBIMED in 2011, the company has completed several health technology expert projects, as well as organized and prepared dozens of public and private training packages and presentations. USBIMED was founded in February 2011. The owner of USBIMED has more than 20 years of experience in the health technology field and almost a decade of experience in the medical field.

� USBIMED was founded in February 2011. The owner of USBIMED has more than 20 years of experience in the health technology field and almost a decade of prior experience in the medical field. CONTACT Terhi Holappa Suopunkitie 4 A 90650 Oulu Finland +358 40 5595 726 terhi.holappa@usbimed.fi www.usbimed.fi


BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

VALIRX FINLAND LTD �

SPECIAL KNOW-HOW • Oncology preclinical and early stage clinical product development • In and out technology licensing • Patent protection • Fundraising and access to capital

• NAV3 oncology biomarker and cancer screening test for finding cancer cells in tissue or cell samples

PRODUCTS/SERVICES Therapeutic development (a) and diagnostics (b): (a) Val201 in clinical development for prostate cancer, preclinical development for other hormone-induced cancer indications such as breast and ovarian cancer as well as endometriosis • Val101 in preclinical development for apoptosis induction in oncological indications (a and b) Oncology biomarker development for hormone induced cancer indications and apoptosis (a and b) GeneICE technology discovery and development platform for specific downregulation of gene activity

REFERENCES/SELECTED REFERENCES www.valirx.com/investor relations www.oamk.fi/laboratoriopalvelut • ValiRx Finland is a fully owned subsidiary of ValiRx Plc • Valirx Plc listed on London AIM market Oct 2006 • Valirx Finland Oy Acquired Dec 2011 • The company was established in 2009

• • • •

(b) Biomarker diagnostics services for health biomarkers

ValiRx Finland is a fully owned subsidiary of ValiRx Plc Valirx Plc listed on London AIM market Oct 2006 Valirx Finland Oy Acquired Dec 2011 The company established year 2009

CONTACT Head office: ValiRx Plc 48-49 Russell Square London WC1B 4JP, UK +44 (0) 207 580 6693 Finland office: ValiRx Finland Oulun Seudun Ammattikorkeakoulu Kiviharjuntie 8 90220 Oulu, Finland +358 (0) 40 506 4497

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BUSINESS AREA:

HEALTH IT Ÿ HEALTH / WELLNESS SERVICES Ÿ DIAGNOSTICS Ÿ MEDTECH Ÿ

PHARMACEUTICALS Ÿ BIOTECH Ÿ OTHER PRODUCTS AND SERVICES

VALKEE LTD Valkee, a young and innovative company from Oulu, Finland, has developed a portable Valkee Bright Light Headset. Valkee substitutes the mood-elevating effects of the sun by channeling bright light directly to photosensitive regions of the brain through the ear canal. Valkee’s potential health effects are wide and yet only partly explored. The Valkee Bright Light Headset is based on a strong scientific foundation: Research cooperation with the University of Oulu has continued since 2008. Valkee has found light-sensitive proteins in the human brain and proved that the human brain is directly responsive to light. Valkee has a medical device approval with the CE Class II(a) certification in EU. The effectiveness against seasonal affective disorder (SAD) has been clinically tested.

SPECIAL KNOW-HOW Human physiology; life science technology; impacts of bright light on health and wellness. PRODUCTS/SERVICES • Valkee 2 Bright Light Headset (black and silver) • Valkee Accessories (silicone ear plugs, wall charger, micro-USB cable, carrying bags) MyValkee web application MAJOR ACKNOWLEDGEMENTS • CE Class II(a) medical device certification RedDot Design Award 2014 • INNOSUOMI 2010 award in Finland (for young, innovative companies) • INNOSUOMI 2010 prize in Finland (for young, innovative companies) REFERENCES/SELECTED REFERENCES Summary of published, peer-reviewed articles in scientific journals: 1. Transcranial bright light exposure via ear canals does not suppress nocturnal melatonin in healthy adults - a single-blind, shamcontrolled, crossover trial. Journal: Chronobiol Int. 2014 Aug;31(7):855-60. 2. Effects of bright light treatment on psychomotor speed in athletes. Journal: Front Physiol. 2014 May 3. Can transcranial brain-targeted bright light treatment via ear canals be effective in relieving symptoms in seasonal affective disorder? A pilot study. Journal: Med Hypotheses. 2012 Apr;78(4):511-5. 60/ LIFE SCIENCE IN OULU

4. Stimulating brain tissue with bright light alters functional connectivity in brain at the resting state. Journal: World Journal of Neuroscience 2012; 2:81-90. 5. Altered resting-state activity in seasonal affective disorder. Journal: Hum Brain Mapp. 2014 Jan;35(1):161-72. 6. Group-ICA model order highlights patterns of functional brain connectivity. Journal: Front Syst Neurosci 2011;5(37):1-17. 7. Encephalopsin (OPN3) protein abundance in the adult mouse brain. Journal: J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2012 Nov;198(11):833-9

� Head office in Oulu, office in Helsinki. Size: 15 permanent employees + occasional, seasonal help; Turnover in 2012: 2M The company was established in 2007. History: In 2005, biologist Juuso Nissilä introduced his childhood friend Antti Aunio to the concept of in-ear bright light therapy. Since his time as a student of biology, Juuso had been conducting research to test and prove that the human brain is photosensitive, in the same way that the brains of many animals have been proven to be. From this exploration Nissilä developed the concept of Valkee, and with the help of Aunio, quickly turned this brain science into the current Valkee product. CONTACT Annikka Impiö Elektroniikkatie 4 90590 Oulu, Finland tel: +358 8 415 21 200 email: info@valkee.com www.valkee.com


BUSINESS AREA:

INVEST IN SPECTACULAR

life sciences Oulu offers a world-class ecosystem in Life science sector. Expertise arises from co-operation with research, public operators and private companies. Active promotion is managed by OuluHealth players, who have formed a strong network between the private and public sector. 240

HI-TECH COMPANIES â&#x201A;Ź

TURNOVER (EUR)

500 MILLION

EMPLOYEES

4.900

PL 22, 90015 Oulun kaupunki Yrttipellontie 6, 90230 Oulu (08) 558 558 10 info@businessoulu.com www.businessoulu.com LIFE SCIENCE IN OULU \ 61

LIFE SCIENCE IN OULU – Company Cataloque 2016  

The life science ecosystem in Oulu is one of the strongest in Finland. It is based on a combination of business- and scientific disciplines...

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