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An interview with Lee Know


“Benefits of Cannabis without the High” By Jason Sebeslav

LEE KNOW is a licensed naturopathic doctor, recipient of several awards, and has held positions as medical advisor, scientific evaluator, and director of R&D for major organizations. He’s the author of Mitochondria and the Future of Medicine (Chelsea Green Publishing, 2018) and the Director of Scientific Affairs for Cannanda. I had the opportunity to speak with Dr. Know recently about the role of terpenes in stimulating the body’s endocannabinoid system for pain relief and other health benefits. Jason Sebeslav: Dr. Know, there seems to be plenty

of research on the therapeutic potential of terpenes, particularly for pain. First, what are terpenes, and second, why haven’t we heard very much about them until now? Lee Know: Terpenes are considered the “active” compounds in essential oils, and although the scientific community has known about these for many years, it’s only recently that they’re gaining recognition from the general public. JS: So, are terpenes the compounds that make aromatherapy effective? LK: Exactly. When we inhale the vapours of essential oils, we breathe in the terpenes, which then get absorbed through our lungs. JS: What makes the terpenes used in Cannanda’s product line unique and so effective? LK: Unlike essential oils, which contain a mix of various terpenes—many of which may not contribute to the effect you’re looking for, or just function as a scent—Cannanda starts with isolated terpenes to create our own blends where 100% of the formula is committed to the therapeutic effect you’re after. Think of our blends as super-potent essential oils that are highly targeted to specific biological processes. For example, our CB2 products effectively target the endocannabinoid system. JS: Most of us were not aware that we had an “endocannabinoid system.” What is it? LK: The endocannabinoid system (ECS) functions as the master regulator of homeostasis—balance within the body— and found within every tissue and organ. It’s made up of two main cannabinoid receptors (called CB1 and CB2) and “endocannabinoids” (which are produced by the body and mimics compounds from cannabis). When the normal function of our tissues or organs are disrupted, that specific area of the body produces more cannabinoid receptors, which are then activated by our endocannabinoids to bring things back into balance.




HWS ~ Health, Wellness & Safety Magazine Volume 9 Issue 3  
HWS ~ Health, Wellness & Safety Magazine Volume 9 Issue 3